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Items: 10


CRISPR/Cas9-Directed Gene Editing for the Generation of Loss-of-Function Mutants in High-Throughput Zebrafish F0 Screens.

Shankaran SS, Dahlem TJ, Bisgrove BW, Yost HJ, Tristani-Firouzi M.

Curr Protoc Mol Biol. 2017 Jul 5;119:31.9.1-31.9.22. doi: 10.1002/cpmb.42.


Genome-Wide CRISPR-Cas9 Screen Identifies MicroRNAs That Regulate Myeloid Leukemia Cell Growth.

Wallace J, Hu R, Mosbruger TL, Dahlem TJ, Stephens WZ, Rao DS, Round JL, O'Connell RM.

PLoS One. 2016 Apr 15;11(4):e0153689. doi: 10.1371/journal.pone.0153689. eCollection 2016.


Silencing of end-joining repair for efficient site-specific gene insertion after TALEN/CRISPR mutagenesis in Aedes aegypti.

Basu S, Aryan A, Overcash JM, Samuel GH, Anderson MA, Dahlem TJ, Myles KM, Adelman ZN.

Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):4038-43. doi: 10.1073/pnas.1502370112. Epub 2015 Mar 16.


Rapid and efficient zebrafish genotyping using PCR with high-resolution melt analysis.

Xing L, Quist TS, Stevenson TJ, Dahlem TJ, Bonkowsky JL.

J Vis Exp. 2014 Feb 5;(84):e51138. doi: 10.3791/51138.


Comparing zinc finger nucleases and transcription activator-like effector nucleases for gene targeting in Drosophila.

Beumer KJ, Trautman JK, Christian M, Dahlem TJ, Lake CM, Hawley RS, Grunwald DJ, Voytas DF, Carroll D.

G3 (Bethesda). 2013 Oct 3;3(10):1717-25. doi: 10.1534/g3.113.007260.


Deletion of Snai2 and Snai3 results in impaired physical development compounded by lymphocyte deficiency.

Pioli PD, Dahlem TJ, Weis JJ, Weis JH.

PLoS One. 2013 Jul 16;8(7):e69216. doi: 10.1371/journal.pone.0069216. Print 2013.


Targeting human microRNA genes using engineered Tal-effector nucleases (TALENs).

Hu R, Wallace J, Dahlem TJ, Grunwald DJ, O'Connell RM.

PLoS One. 2013 May 7;8(5):e63074. doi: 10.1371/journal.pone.0063074. Print 2013.


Efficient identification of TALEN-mediated genome modifications using heteroduplex mobility assays.

Ota S, Hisano Y, Muraki M, Hoshijima K, Dahlem TJ, Grunwald DJ, Okada Y, Kawahara A.

Genes Cells. 2013 Jun;18(6):450-8. doi: 10.1111/gtc.12050. Epub 2013 Apr 11.


Simple methods for generating and detecting locus-specific mutations induced with TALENs in the zebrafish genome.

Dahlem TJ, Hoshijima K, Jurynec MJ, Gunther D, Starker CG, Locke AS, Weis AM, Voytas DF, Grunwald DJ.

PLoS Genet. 2012;8(8):e1002861. doi: 10.1371/journal.pgen.1002861. Epub 2012 Aug 16.


Transcriptional control of Pactolus: evidence of a negative control region and comparison with its evolutionary paralogue, CD18 (beta2 integrin).

Hale JS, Dahlem TJ, Margraf RL, Debnath I, Weis JJ, Weis JH.

J Leukoc Biol. 2006 Aug;80(2):383-98. Epub 2006 May 30.


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