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Items: 32

1.

Involvement of DNA mismatch repair in the maintenance of heterochromatic DNA stability in Saccharomyces cerevisiae.

Dahal BK, Kadyrova LY, Delfino KR, Rogozin IB, Gujar V, Lobachev KS, Kadyrov FA.

PLoS Genet. 2017 Oct 25;13(10):e1007074. doi: 10.1371/journal.pgen.1007074. eCollection 2017 Oct.

2.

Interaction of proliferating cell nuclear antigen with PMS2 is required for MutLα activation and function in mismatch repair.

Genschel J, Kadyrova LY, Iyer RR, Dahal BK, Kadyrov FA, Modrich P.

Proc Natl Acad Sci U S A. 2017 May 9;114(19):4930-4935. doi: 10.1073/pnas.1702561114. Epub 2017 Apr 24.

3.

Pressure overload leads to an increased accumulation and activity of mast cells in the right ventricle.

Luitel H, Sydykov A, Schymura Y, Mamazhakypov A, Janssen W, Pradhan K, Wietelmann A, Kosanovic D, Dahal BK, Weissmann N, Seeger W, Grimminger F, Ghofrani HA, Schermuly RT.

Physiol Rep. 2017 Mar;5(6). pii: e13146. doi: 10.14814/phy2.13146.

4.

The Major Replicative Histone Chaperone CAF-1 Suppresses the Activity of the DNA Mismatch Repair System in the Cytotoxic Response to a DNA-methylating Agent.

Kadyrova LY, Dahal BK, Kadyrov FA.

J Biol Chem. 2016 Dec 30;291(53):27298-27312. doi: 10.1074/jbc.M116.760561. Epub 2016 Nov 21.

5.

miR-223-IGF-IR signalling in hypoxia- and load-induced right-ventricular failure: a novel therapeutic approach.

Shi L, Kojonazarov B, Elgheznawy A, Popp R, Dahal BK, Böhm M, Pullamsetti SS, Ghofrani HA, Gödecke A, Jungmann A, Katus HA, Müller OJ, Schermuly RT, Fisslthaler B, Seeger W, Fleming I.

Cardiovasc Res. 2016 Aug 1;111(3):184-93. doi: 10.1093/cvr/cvw065. Epub 2016 Mar 24.

PMID:
27013635
6.

Endothelial actions of atrial natriuretic peptide prevent pulmonary hypertension in mice.

Werner F, Kojonazarov B, Gaßner B, Abeßer M, Schuh K, Völker K, Baba HA, Dahal BK, Schermuly RT, Kuhn M.

Basic Res Cardiol. 2016 Mar;111(2):22. doi: 10.1007/s00395-016-0541-x. Epub 2016 Feb 24.

7.

Evidence that the DNA mismatch repair system removes 1-nucleotide Okazaki fragment flaps.

Kadyrova LY, Dahal BK, Kadyrov FA.

J Biol Chem. 2015 Oct 2;290(40):24051-65. doi: 10.1074/jbc.M115.660357. Epub 2015 Jul 29.

8.

Chymase: a multifunctional player in pulmonary hypertension associated with lung fibrosis.

Kosanovic D, Luitel H, Dahal BK, Cornitescu T, Janssen W, Danser AH, Garrelds IM, De Mey JG, Fazzi G, Schiffers P, Iglarz M, Fischli W, Ghofrani HA, Weissmann N, Grimminger F, Seeger W, Reiss I, Schermuly RT.

Eur Respir J. 2015 Oct;46(4):1084-94. doi: 10.1183/09031936.00018215. Epub 2015 Jun 25.

9.

Hypoxia- or PDGF-BB-dependent paxillin tyrosine phosphorylation in pulmonary hypertension is reversed by HIF-1α depletion or imatinib treatment.

Veith C, Zakrzewicz D, Dahal BK, Bálint Z, Murmann K, Wygrecka M, Seeger W, Schermuly RT, Weissmann N, Kwapiszewska G.

Thromb Haemost. 2014 Dec;112(6):1288-303. doi: 10.1160/TH13-12-1031. Epub 2014 Sep 18.

PMID:
25231004
10.

Histological characterization of mast cell chymase in patients with pulmonary hypertension and chronic obstructive pulmonary disease.

Kosanovic D, Dahal BK, Peters DM, Seimetz M, Wygrecka M, Hoffmann K, Antel J, Reiss I, Ghofrani HA, Weissmann N, Grimminger F, Seeger W, Schermuly RT.

Pulm Circ. 2014 Mar;4(1):128-36. doi: 10.1086/675642.

11.

The peroxisome proliferator-activated receptor β/δ agonist GW0742 has direct protective effects on right heart hypertrophy.

Kojonazarov B, Luitel H, Sydykov A, Dahal BK, Paul-Clark MJ, Bonvini S, Reed A, Schermuly RT, Mitchell JA.

Pulm Circ. 2013 Dec;3(4):926-35. doi: 10.1086/674755. Erratum in: Pulm Circ. 2014 Jun;4(2):352.

12.

Rhodiola: an ordinary plant or a promising future therapy for pulmonary hypertension? a brief review.

Kosanovic D, Tian X, Pak O, Lai YJ, Hsieh YL, Seimetz M, Weissmann N, Schermuly RT, Dahal BK.

Pulm Circ. 2013 Sep;3(3):499-506. doi: 10.1086/674303. Epub 2013 Nov 11.

13.

ASSESSMENT OF DETECTION EFFICACY OF MYCOBACTERIUM TUBERCULOSIS IN SPUTUM SAMPLES BY REAL TIME PCR BASED METHOD.

Upadhyaya SK, Dixit SM, Shrestha S, Dangol SD, Pokhrel D, Banjara S, Shrestha KS, Hengoju S, Dahal BK.

J Sci Eng Technol. 2013 Jul;9(1):181-188.

14.

Mast cells and fibroblasts work in concert to aggravate pulmonary fibrosis: role of transmembrane SCF and the PAR-2/PKC-α/Raf-1/p44/42 signaling pathway.

Wygrecka M, Dahal BK, Kosanovic D, Petersen F, Taborski B, von Gerlach S, Didiasova M, Zakrzewicz D, Preissner KT, Schermuly RT, Markart P.

Am J Pathol. 2013 Jun;182(6):2094-108. doi: 10.1016/j.ajpath.2013.02.013. Epub 2013 Apr 4.

PMID:
23562441
15.

Mast cell chymase: an indispensable instrument in the pathological symphony of idiopathic pulmonary fibrosis?

Kosanovic D, Dahal BK, Wygrecka M, Reiss I, Günther A, Ghofrani HA, Weissmann N, Grimminger F, Seeger W, Schermuly RT, Banat GA.

Histol Histopathol. 2013 Jun;28(6):691-9. doi: 10.14670/HH-28.691. Epub 2013 Feb 25. Review.

PMID:
23436625
16.

Cofilin, a hypoxia-regulated protein in murine lungs identified by 2DE: role of the cytoskeletal protein cofilin in pulmonary hypertension.

Veith C, Schmitt S, Veit F, Dahal BK, Wilhelm J, Klepetko W, Marta G, Seeger W, Schermuly RT, Grimminger F, Ghofrani HA, Fink L, Weissmann N, Kwapiszewska G.

Proteomics. 2013 Jan;13(1):75-88. doi: 10.1002/pmic.201200206.

PMID:
23161571
17.

Immune and inflammatory cell involvement in the pathology of idiopathic pulmonary arterial hypertension.

Savai R, Pullamsetti SS, Kolbe J, Bieniek E, Voswinckel R, Fink L, Scheed A, Ritter C, Dahal BK, Vater A, Klussmann S, Ghofrani HA, Weissmann N, Klepetko W, Banat GA, Seeger W, Grimminger F, Schermuly RT.

Am J Respir Crit Care Med. 2012 Nov 1;186(9):897-908. doi: 10.1164/rccm.201202-0335OC. Epub 2012 Sep 6.

PMID:
22955318
18.

Effects of multikinase inhibitors on pressure overload-induced right ventricular remodeling.

Kojonazarov B, Sydykov A, Pullamsetti SS, Luitel H, Dahal BK, Kosanovic D, Tian X, Majewski M, Baumann C, Evans S, Phillips P, Fairman D, Davie N, Wayman C, Kilty I, Weissmann N, Grimminger F, Seeger W, Ghofrani HA, Schermuly RT.

Int J Cardiol. 2013 Sep 10;167(6):2630-7. doi: 10.1016/j.ijcard.2012.06.129. Epub 2012 Jul 31.

PMID:
22854298
19.

Role of Src tyrosine kinases in experimental pulmonary hypertension.

Pullamsetti SS, Berghausen EM, Dabral S, Tretyn A, Butrous E, Savai R, Butrous G, Dahal BK, Brandes RP, Ghofrani HA, Weissmann N, Grimminger F, Seeger W, Rosenkranz S, Schermuly RT.

Arterioscler Thromb Vasc Biol. 2012 Jun;32(6):1354-65. doi: 10.1161/ATVBAHA.112.248500. Epub 2012 Apr 19.

PMID:
22516066
20.

PAR-2 inhibition reverses experimental pulmonary hypertension.

Kwapiszewska G, Markart P, Dahal BK, Kojonazarov B, Marsh LM, Schermuly RT, Taube C, Meinhardt A, Ghofrani HA, Steinhoff M, Seeger W, Preissner KT, Olschewski A, Weissmann N, Wygrecka M.

Circ Res. 2012 Apr 27;110(9):1179-91. doi: 10.1161/CIRCRESAHA.111.257568. Epub 2012 Mar 29.

PMID:
22461388
21.

Inhibition of microRNA-17 improves lung and heart function in experimental pulmonary hypertension.

Pullamsetti SS, Doebele C, Fischer A, Savai R, Kojonazarov B, Dahal BK, Ghofrani HA, Weissmann N, Grimminger F, Bonauer A, Seeger W, Zeiher AM, Dimmeler S, Schermuly RT.

Am J Respir Crit Care Med. 2012 Feb 15;185(4):409-19. doi: 10.1164/rccm.201106-1093OC. Epub 2011 Dec 8.

PMID:
22161164
22.

Hypoxic pulmonary hypertension in mice with constitutively active platelet-derived growth factor receptor-β.

Dahal BK, Heuchel R, Pullamsetti SS, Wilhelm J, Ghofrani HA, Weissmann N, Seeger W, Grimminger F, Schermuly RT.

Pulm Circ. 2011 Apr-Jun;1(2):259-68. doi: 10.4103/2045-8932.83448.

23.

Therapeutic efficacy of TBC3711 in monocrotaline-induced pulmonary hypertension.

Kosanovic D, Kojonazarov B, Luitel H, Dahal BK, Sydykov A, Cornitescu T, Janssen W, Brandes RP, Davie N, Ghofrani HA, Weissmann N, Grimminger F, Seeger W, Schermuly RT.

Respir Res. 2011 Jun 23;12:87. doi: 10.1186/1465-9921-12-87.

24.

The role of dimethylarginine dimethylaminohydrolase in idiopathic pulmonary fibrosis.

Pullamsetti SS, Savai R, Dumitrascu R, Dahal BK, Wilhelm J, Konigshoff M, Zakrzewicz D, Ghofrani HA, Weissmann N, Eickelberg O, Guenther A, Leiper J, Seeger W, Grimminger F, Schermuly RT.

Sci Transl Med. 2011 Jun 15;3(87):87ra53. doi: 10.1126/scitranslmed.3001725.

25.

Involvement of mast cells in monocrotaline-induced pulmonary hypertension in rats.

Dahal BK, Kosanovic D, Kaulen C, Cornitescu T, Savai R, Hoffmann J, Reiss I, Ghofrani HA, Weissmann N, Kuebler WM, Seeger W, Grimminger F, Schermuly RT.

Respir Res. 2011 May 2;12:60. doi: 10.1186/1465-9921-12-60.

26.

Hypoxia enhances platelet-derived growth factor signaling in the pulmonary vasculature by down-regulation of protein tyrosine phosphatases.

ten Freyhaus H, Dagnell M, Leuchs M, Vantler M, Berghausen EM, Caglayan E, Weissmann N, Dahal BK, Schermuly RT, Ostman A, Kappert K, Rosenkranz S.

Am J Respir Crit Care Med. 2011 Apr 15;183(8):1092-102. doi: 10.1164/rccm.200911-1663OC. Epub 2010 Dec 22.

PMID:
21177885
27.

Nebulization of the acidified sodium nitrite formulation attenuates acute hypoxic pulmonary vasoconstriction.

Egemnazarov B, Schermuly RT, Dahal BK, Elliott GT, Hoglen NC, Surber MW, Weissmann N, Grimminger F, Seeger W, Ghofrani HA.

Respir Res. 2010 Jun 21;11:81. doi: 10.1186/1465-9921-11-81.

28.

Inflammation, immunological reaction and role of infection in pulmonary hypertension.

Pullamsetti SS, Savai R, Janssen W, Dahal BK, Seeger W, Grimminger F, Ghofrani HA, Weissmann N, Schermuly RT.

Clin Microbiol Infect. 2011 Jan;17(1):7-14. doi: 10.1111/j.1469-0691.2010.03285.x. Review.

29.

Therapeutic efficacy of azaindole-1 in experimental pulmonary hypertension.

Dahal BK, Kosanovic D, Pamarthi PK, Sydykov A, Lai YJ, Kast R, Schirok H, Stasch JP, Ghofrani HA, Weissmann N, Grimminger F, Seeger W, Schermuly RT.

Eur Respir J. 2010 Oct;36(4):808-18. doi: 10.1183/09031936.00140309. Epub 2010 Jun 7.

30.

Role of epidermal growth factor inhibition in experimental pulmonary hypertension.

Dahal BK, Cornitescu T, Tretyn A, Pullamsetti SS, Kosanovic D, Dumitrascu R, Ghofrani HA, Weissmann N, Voswinckel R, Banat GA, Seeger W, Grimminger F, Schermuly RT.

Am J Respir Crit Care Med. 2010 Jan 15;181(2):158-67. doi: 10.1164/rccm.200811-1682OC. Epub 2009 Oct 22.

PMID:
19850946
31.

The soluble guanylate cyclase activator HMR1766 reverses hypoxia-induced experimental pulmonary hypertension in mice.

Weissmann N, Hackemack S, Dahal BK, Pullamsetti SS, Savai R, Mittal M, Fuchs B, Medebach T, Dumitrascu R, Eickels Mv, Ghofrani HA, Seeger W, Grimminger F, Schermuly RT.

Am J Physiol Lung Cell Mol Physiol. 2009 Oct;297(4):L658-65. doi: 10.1152/ajplung.00189.2009. Epub 2009 Jul 17.

32.

Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation.

Raes G, Brys L, Dahal BK, Brandt J, Grooten J, Brombacher F, Vanham G, Noël W, Bogaert P, Boonefaes T, Kindt A, Van den Bergh R, Leenen PJ, De Baetselier P, Ghassabeh GH.

J Leukoc Biol. 2005 Mar;77(3):321-7. Epub 2004 Dec 9.

PMID:
15591125

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