Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 683

1.

Complement Therapeutics in the Multi-Organ Donor: Do or Don't?

van Zanden JE, Jager NM, Daha MR, Erasmus ME, Leuvenink HGD, Seelen MA.

Front Immunol. 2019 Feb 27;10:329. doi: 10.3389/fimmu.2019.00329. eCollection 2019. Review.

2.

Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population.

Gaya da Costa M, Poppelaars F, van Kooten C, Mollnes TE, Tedesco F, Würzner R, Trouw LA, Truedsson L, Daha MR, Roos A, Seelen MA.

Front Immunol. 2018 Nov 20;9:2664. doi: 10.3389/fimmu.2018.02664. eCollection 2018.

3.

Taming hemodialysis-induced inflammation: Are complement C3 inhibitors a viable option?

Mastellos DC, Reis ES, Biglarnia AR, Waldman M, Quigg RJ, Huber-Lang M, Seelen MA, Daha MR, Lambris JD.

Clin Immunol. 2019 Jan;198:102-105. doi: 10.1016/j.clim.2018.11.010. Epub 2018 Nov 22.

PMID:
30472267
4.

Protocol and rationale for the first South Asian 5-year prospective longitudinal observational cohort study and biomarker evaluation investigating the clinical course and risk profile of IgA nephropathy: GRACE IgANI cohort.

Alexander S, John GT, Korula A, Vijayakumar TS, David VG, Mohapatra A, Valson AT, Jacob S, Koshy PM, Rajan G, John EE, Matthai SM, Jeyaseelan L, Ponnusamy B, Cook T, Pusey C, Daha MR, Feehally J, Barratt J, Varughese S.

Wellcome Open Res. 2018 Jul 26;3:91. doi: 10.12688/wellcomeopenres.14644.1. eCollection 2018.

5.

Properdin binds independent of complement activation in an in vivo model of anti-glomerular basement membrane disease.

O'Flynn J, Kotimaa J, Faber-Krol R, Koekkoek K, Klar-Mohamad N, Koudijs A, Schwaeble WJ, Stover C, Daha MR, van Kooten C.

Kidney Int. 2018 Dec;94(6):1141-1150. doi: 10.1016/j.kint.2018.06.030. Epub 2018 Oct 12.

PMID:
30322716
6.

Intradialytic Complement Activation Precedes the Development of Cardiovascular Events in Hemodialysis Patients.

Poppelaars F, Gaya da Costa M, Faria B, Berger SP, Assa S, Daha MR, Medina Pestana JO, van Son WJ, Franssen CFM, Seelen MA.

Front Immunol. 2018 Sep 13;9:2070. doi: 10.3389/fimmu.2018.02070. eCollection 2018.

7.

IgA nephropathy: new insights into the role of complement.

Floege J, Daha MR.

Kidney Int. 2018 Jul;94(1):16-18. doi: 10.1016/j.kint.2018.03.009.

PMID:
29933843
8.

Novel Approaches to Control of the Alternative Complement Pathway for the Treatment of C3 Glomerulopathies.

Daha MR, Seelen M.

J Am Soc Nephrol. 2018 Aug;29(8):2032-2033. doi: 10.1681/ASN.2018050554. Epub 2018 Jun 19. No abstract available.

9.

Complement Activation During Ischemia/Reperfusion Injury Induces Pericyte-to-Myofibroblast Transdifferentiation Regulating Peritubular Capillary Lumen Reduction Through pERK Signaling.

Castellano G, Franzin R, Stasi A, Divella C, Sallustio F, Pontrelli P, Lucarelli G, Battaglia M, Staffieri F, Crovace A, Stallone G, Seelen M, Daha MR, Grandaliano G, Gesualdo L.

Front Immunol. 2018 May 23;9:1002. doi: 10.3389/fimmu.2018.01002. eCollection 2018.

10.

The lectin pathway in renal disease: old concept and new insights.

Gaya da Costa M, Poppelaars F, Berger SP, Daha MR, Seelen MA.

Nephrol Dial Transplant. 2018 Dec 1;33(12):2073-2079. doi: 10.1093/ndt/gfy073.

PMID:
29701808
11.

The Complement System in Dialysis: A Forgotten Story?

Poppelaars F, Faria B, Gaya da Costa M, Franssen CFM, van Son WJ, Berger SP, Daha MR, Seelen MA.

Front Immunol. 2018 Jan 25;9:71. doi: 10.3389/fimmu.2018.00071. eCollection 2018. Review.

12.

Genome-Wide Association Study Reveals Variants in CFH and CFHR4 Associated with Systemic Complement Activation: Implications in Age-Related Macular Degeneration.

Lorés-Motta L, Paun CC, Corominas J, Pauper M, Geerlings MJ, Altay L, Schick T, Daha MR, Fauser S, Hoyng CB, den Hollander AI, de Jong EK.

Ophthalmology. 2018 Jul;125(7):1064-1074. doi: 10.1016/j.ophtha.2017.12.023. Epub 2018 Feb 2.

13.

Endothelial heparan sulfate deficiency reduces inflammation and fibrosis in murine diabetic nephropathy.

Talsma DT, Katta K, Ettema MAB, Kel B, Kusche-Gullberg M, Daha MR, Stegeman CA, van den Born J, Wang L.

Lab Invest. 2018 Apr;98(4):427-438. doi: 10.1038/s41374-017-0015-2. Epub 2018 Jan 12.

14.

C1-Inhibitor Treatment Decreases Renal Injury in an Established Brain-Dead Rat Model.

Poppelaars F, Jager NM, Kotimaa J, Leuvenink HGD, Daha MR, van Kooten C, Seelen MA, Damman J.

Transplantation. 2018 Jan;102(1):79-87. doi: 10.1097/TP.0000000000001895.

PMID:
28731906
15.

Complement in renal transplantation: The road to translation.

Jager NM, Poppelaars F, Daha MR, Seelen MA.

Mol Immunol. 2017 Sep;89:22-35. doi: 10.1016/j.molimm.2017.05.014. Epub 2017 May 27. Review.

PMID:
28558950
16.

The bittersweet taste of tubulo-interstitial glycans.

Talsma DT, Daha MR, van den Born J.

Nephrol Dial Transplant. 2017 Apr 1;32(4):611-619. doi: 10.1093/ndt/gfw371. Review.

PMID:
28407128
17.

Critical role for complement receptor C5aR2 in the pathogenesis of renal ischemia-reperfusion injury.

Poppelaars F, van Werkhoven MB, Kotimaa J, Veldhuis ZJ, Ausema A, Broeren SGM, Damman J, Hempel JC, Leuvenink HGD, Daha MR, van Son WJ, van Kooten C, van Os RP, Hillebrands JL, Seelen MA.

FASEB J. 2017 Jul;31(7):3193-3204. doi: 10.1096/fj.201601218R. Epub 2017 Apr 10.

PMID:
28396344
18.

Properdin and factor H production by human dendritic cells modulates their T-cell stimulatory capacity and is regulated by IFN-γ.

Dixon KO, O'Flynn J, Klar-Mohamad N, Daha MR, van Kooten C.

Eur J Immunol. 2017 Mar;47(3):470-480. doi: 10.1002/eji.201646703.

19.

Distinct in vitro Complement Activation by Various Intravenous Iron Preparations.

Hempel JC, Poppelaars F, Gaya da Costa M, Franssen CF, de Vlaam TP, Daha MR, Berger SP, Seelen MA, Gaillard CA.

Am J Nephrol. 2017;45(1):49-59. doi: 10.1159/000451060. Epub 2016 Nov 26.

20.

Erratum to: Strong predictive value of mannose-binding lectin levels for cardiovascular risk of hemodialysis patients.

Poppelaars F, Gaya da Costa M, Berger SP, Assa S, Meter-Arkema AH, Daha MR, van Son WJ, Franssen CF, Seelen MA.

J Transl Med. 2016 Aug 24;14(1):245. No abstract available.

21.

Strong predictive value of mannose-binding lectin levels for cardiovascular risk of hemodialysis patients.

Poppelaars F, Gaya da Costa M, Berger SP, Assa S, Meter-Arkema AH, Daha MR, van Son WJ, Franssen CF, Seelen MA.

J Transl Med. 2016 Aug 5;14(1):236. doi: 10.1186/s12967-016-0995-5. Erratum in: J Transl Med. 2016;14(1):245.

22.

Can eculizumab be discontinued in aHUS?: Case report and review of the literature.

Sahutoglu T, Basturk T, Sakaci T, Koc Y, Ahbap E, Sevinc M, Kara E, Akgol C, Caglayan FB, Unsal A, Daha MR.

Medicine (Baltimore). 2016 Aug;95(31):e4330. doi: 10.1097/MD.0000000000004330. Review.

23.

Sex matters: Systemic complement activity of female C57BL/6J and BALB/cJ mice is limited by serum terminal pathway components.

Kotimaa J, Klar-Mohammad N, Gueler F, Schilders G, Jansen A, Rutjes H, Daha MR, van Kooten C.

Mol Immunol. 2016 Aug;76:13-21. doi: 10.1016/j.molimm.2016.06.004. Epub 2016 Jun 20.

24.

Analysis of Risk Alleles and Complement Activation Levels in Familial and Non-Familial Age-Related Macular Degeneration.

Saksens NT, Lechanteur YT, Verbakel SK, Groenewoud JM, Daha MR, Schick T, Fauser S, Boon CJ, Hoyng CB, den Hollander AI.

PLoS One. 2016 Jun 3;11(6):e0144367. doi: 10.1371/journal.pone.0144367. eCollection 2016.

25.

A Novel Complotype Combination Associates with Age-Related Macular Degeneration and High Complement Activation Levels in vivo.

Paun CC, Lechanteur YTE, Groenewoud JMM, Altay L, Schick T, Daha MR, Fauser S, Hoyng CB, den Hollander AI, de Jong EK.

Sci Rep. 2016 May 31;6:26568. doi: 10.1038/srep26568.

26.

Monomeric C-reactive protein inhibits renal cell-directed complement activation mediated by properdin.

O'Flynn J, van der Pol P, Dixon KO, Prohászka Z, Daha MR, van Kooten C.

Am J Physiol Renal Physiol. 2016 Jun 1;310(11):F1308-16. doi: 10.1152/ajprenal.00645.2014. Epub 2016 Mar 16.

27.

New insight into the effects of heparinoids on complement inhibition by C1-inhibitor.

Poppelaars F, Damman J, de Vrij EL, Burgerhof JG, Saye J, Daha MR, Leuvenink HG, Uknis ME, Seelen MA.

Clin Exp Immunol. 2016 Jun;184(3):378-88. doi: 10.1111/cei.12777. Epub 2016 Apr 13.

28.

Rare Genetic Variants Associated With Development of Age-Related Macular Degeneration.

Saksens NT, Geerlings MJ, Bakker B, Schick T, Daha MR, Fauser S, Boon CJ, de Jong EK, Hoyng CB, den Hollander AI.

JAMA Ophthalmol. 2016 Mar;134(3):287-93. doi: 10.1001/jamaophthalmol.2015.5592.

PMID:
26767664
29.

Mutations in Complement Factor H Impair Alternative Pathway Regulation on Mouse Glomerular Endothelial Cells in Vitro.

Loeven MA, Rops AL, Lehtinen MJ, van Kuppevelt TH, Daha MR, Smith RJ, Bakker M, Berden JH, Rabelink TJ, Jokiranta TS, van der Vlag J.

J Biol Chem. 2016 Mar 4;291(10):4974-81. doi: 10.1074/jbc.M115.702506. Epub 2016 Jan 4.

30.

Role of complement in IgA nephropathy.

Daha MR, van Kooten C.

J Nephrol. 2016 Feb;29(1):1-4. doi: 10.1007/s40620-015-0245-6. Epub 2015 Nov 13. Review.

31.

Functional assessment of mouse complement pathway activities and quantification of C3b/C3c/iC3b in an experimental model of mouse renal ischaemia/reperfusion injury.

Kotimaa JP, van Werkhoven MB, O'Flynn J, Klar-Mohamad N, van Groningen J, Schilders G, Rutjes H, Daha MR, Seelen MA, van Kooten C.

J Immunol Methods. 2015 Apr;419:25-34. doi: 10.1016/j.jim.2015.02.010. Epub 2015 Feb 28.

PMID:
25733354
32.

Bortezomib, C1-inhibitor and plasma exchange do not prolong the survival of multi-transgenic GalT-KO pig kidney xenografts in baboons.

Le Bas-Bernardet S, Tillou X, Branchereau J, Dilek N, Poirier N, Châtelais M, Charreau B, Minault D, Hervouet J, Renaudin K, Crossan C, Scobie L, Takeuchi Y, Diswall M, Breimer ME, Klar N, Daha MR, Simioni P, Robson SC, Nottle MB, Salvaris EJ, Cowan PJ, d'Apice AJ, Sachs DH, Yamada K, Lagutina I, Duchi R, Perota A, Lazzari G, Galli C, Cozzi E, Soulillou JP, Vanhove B, Blancho G.

Am J Transplant. 2015 Feb;15(2):358-70. doi: 10.1111/ajt.12988.

33.

The innate immune response.

Koenderman L, Buurman W, Daha MR.

Immunol Lett. 2014 Dec;162(2 Pt B):95-102. doi: 10.1016/j.imlet.2014.10.010. Epub 2014 Oct 19. Review.

PMID:
25455595
34.

Dysregulation of adaptive immune responses in complement C3-deficient patients.

Pekkarinen PT, Heikkilä N, Kisand K, Peterson P, Botto M, Daha MR, Drouet C, Isaac L, Helminen M, Haahtela T, Meri S, Jarva H, Arstila TP.

Eur J Immunol. 2015 Mar;45(3):915-21. doi: 10.1002/eji.201444948. Epub 2015 Jan 19.

35.

Hypoxia and Complement-and-Coagulation Pathways in the Deceased Organ Donor as the Major Target for Intervention to Improve Renal Allograft Outcome.

Damman J, Bloks VW, Daha MR, van der Most PJ, Sanjabi B, van der Vlies P, Snieder H, Ploeg RJ, Krikke C, Leuvenink HG, Seelen MA.

Transplantation. 2015 Jun;99(6):1293-300. doi: 10.1097/TP.0000000000000500.

PMID:
25427168
36.

Zinc supplementation inhibits complement activation in age-related macular degeneration.

Smailhodzic D, van Asten F, Blom AM, Mohlin FC, den Hollander AI, van de Ven JP, van Huet RA, Groenewoud JM, Tian Y, Berendschot TT, Lechanteur YT, Fauser S, de Bruijn C, Daha MR, van der Wilt GJ, Hoyng CB, Klevering BJ.

PLoS One. 2014 Nov 13;9(11):e112682. doi: 10.1371/journal.pone.0112682. eCollection 2014.

37.

Combined C4d and CD3 immunostaining predicts immunoglobulin (Ig)A nephropathy progression.

Faria B, Henriques C, Matos AC, Daha MR, Pestana M, Seelen M.

Clin Exp Immunol. 2015 Feb;179(2):354-61. doi: 10.1111/cei.12461.

38.

The role of heparan sulfate as determining pathogenic factor in complement factor H-associated diseases.

Loeven MA, Rops AL, Berden JH, Daha MR, Rabelink TJ, van der Vlag J.

Mol Immunol. 2015 Feb;63(2):203-8. doi: 10.1016/j.molimm.2014.08.005. Epub 2014 Sep 20. Review.

PMID:
25246018
39.

Functional assessment of rat complement pathway activities and quantification of soluble C5b-9 in an experimental model of renal ischemia/reperfusion injury.

Kotimaa J, van der Pol P, Leijtens S, Klar-Mohammad N, Schilders G, Daha MR, Rutjes H, van Kooten C.

J Immunol Methods. 2014 Oct;412:14-23. doi: 10.1016/j.jim.2014.06.011. Epub 2014 Jun 19.

PMID:
24953215
40.

Impact of the common genetic associations of age-related macular degeneration upon systemic complement component C3d levels.

Ristau T, Paun C, Ersoy L, Hahn M, Lechanteur Y, Hoyng C, de Jong EK, Daha MR, Kirchhof B, den Hollander AI, Fauser S.

PLoS One. 2014 Mar 27;9(3):e93459. doi: 10.1371/journal.pone.0093459. eCollection 2014.

41.

New insights into the pathogenesis of IgA nephropathy.

Floege J, Moura IC, Daha MR.

Semin Immunopathol. 2014 Jul;36(4):431-42. doi: 10.1007/s00281-013-0411-7. Epub 2014 Jan 18. Review.

PMID:
24442210
42.

Complement activation by ceramide transporter proteins.

Bode GH, Losen M, Buurman WA, Veerhuis R, Molenaar PC, Steinbusch HW, De Baets MH, Daha MR, Martinez-Martinez P.

J Immunol. 2014 Feb 1;192(3):1154-61. doi: 10.4049/jimmunol.1301673. Epub 2014 Jan 6.

43.

Myeloperoxidase directs properdin-mediated complement activation.

O'Flynn J, Dixon KO, Faber Krol MC, Daha MR, van Kooten C.

J Innate Immun. 2014;6(4):417-25. doi: 10.1159/000356980. Epub 2013 Dec 20.

44.

Allergy is a protective factor against age-related macular degeneration.

Ristau T, Ersoy L, Lechanteur Y, den Hollander AI, Daha MR, Hahn M, Hoyng CB, Fauser S.

Invest Ophthalmol Vis Sci. 2014 Jan 9;55(1):210-4. doi: 10.1167/iovs.13-13248.

PMID:
24235017
45.

Purification and functional analysis of human properdin.

O'Flynn J, Krol MC, Daha MR, van Kooten C.

Methods Mol Biol. 2014;1100:161-7. doi: 10.1007/978-1-62703-724-2_13.

PMID:
24218258
46.

Heparin/heparan sulphate interactions with complement--a possible target for reduction of renal function loss?

Zaferani A, Talsma D, Richter MK, Daha MR, Navis GJ, Seelen MA, van den Born J.

Nephrol Dial Transplant. 2014 Mar;29(3):515-22. doi: 10.1093/ndt/gft243. Epub 2013 Jul 22. Review.

PMID:
23880790
47.

A functional variant in the CFI gene confers a high risk of age-related macular degeneration.

van de Ven JP, Nilsson SC, Tan PL, Buitendijk GH, Ristau T, Mohlin FC, Nabuurs SB, Schoenmaker-Koller FE, Smailhodzic D, Campochiaro PA, Zack DJ, Duvvari MR, Bakker B, Paun CC, Boon CJ, Uitterlinden AG, Liakopoulos S, Klevering BJ, Fauser S, Daha MR, Katsanis N, Klaver CC, Blom AM, Hoyng CB, den Hollander AI.

Nat Genet. 2013 Jul;45(7):813-7. doi: 10.1038/ng.2640. Epub 2013 May 19.

PMID:
23685748
48.

Complement mediated renal inflammation induced by donor brain death: role of renal C5a-C5aR interaction.

van Werkhoven MB, Damman J, van Dijk MCRF, Daha MR, de Jong IJ, Leliveld A, Krikke C, Leuvenink HG, van Goor H, van Son WJ, Olinga P, Hillebrands JL, Seelen MAJ.

Am J Transplant. 2013 Apr;13(4):875-882. doi: 10.1111/ajt.12130. Epub 2013 Feb 7.

49.

Unexpected role for properdin in complement C3 glomerulopathies.

Daha MR.

J Am Soc Nephrol. 2013 Jan;24(1):5-7. doi: 10.1681/ASN.2012111110. Epub 2012 Dec 14. No abstract available.

50.

Deposition of IgA in primary IgA nephropathy: it takes at least four to tango.

Daha MR, van Kooten C.

Nephrol Dial Transplant. 2013 Apr;28(4):794-7. doi: 10.1093/ndt/gfs445. Epub 2012 Dec 12. Review.

PMID:
23234754

Supplemental Content

Support Center