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Items: 24

1.

HOXA9 Cooperates with Activated JAK/STAT Signaling to Drive Leukemia Development.

de Bock CE, Demeyer S, Degryse S, Verbeke D, Sweron B, Gielen O, Vandepoel R, Vicente C, Vanden Bempt M, Dagklis A, Geerdens E, Bornschein S, Gijsbers R, Soulier J, Meijerink JP, Heinäniemi M, Teppo S, Bouvy-Liivrand M, Lohi O, Radaelli E, Cools J.

Cancer Discov. 2018 May;8(5):616-631. doi: 10.1158/2159-8290.CD-17-0583. Epub 2018 Mar 1.

PMID:
29496663
2.

The Second-Generation Exportin-1 Inhibitor KPT-8602 Demonstrates Potent Activity against Acute Lymphoblastic Leukemia.

Vercruysse T, De Bie J, Neggers JE, Jacquemyn M, Vanstreels E, Schmid-Burgk JL, Hornung V, Baloglu E, Landesman Y, Senapedis W, Shacham S, Dagklis A, Cools J, Daelemans D.

Clin Cancer Res. 2017 May 15;23(10):2528-2541. doi: 10.1158/1078-0432.CCR-16-1580. Epub 2016 Oct 25.

3.

Hedgehog pathway activation in T-cell acute lymphoblastic leukemia predicts response to SMO and GLI1 inhibitors.

Dagklis A, Demeyer S, De Bie J, Radaelli E, Pauwels D, Degryse S, Gielen O, Vicente C, Vandepoel R, Geerdens E, Uyttebroeck A, Boeckx N, de Bock CE, Cools J.

Blood. 2016 Dec 8;128(23):2642-2654. Epub 2016 Sep 30.

4.

Hedgehog pathway mutations in T-cell acute lymphoblastic leukemia.

Dagklis A, Pauwels D, Lahortiga I, Geerdens E, Bittoun E, Cauwelier B, Tousseyn T, Uyttebroeck A, Maertens J, Verhoef G, Vandenberghe P, Cools J.

Haematologica. 2015 Mar;100(3):e102-5. doi: 10.3324/haematol.2014.119248. Epub 2014 Dec 19. No abstract available.

5.

SIGLEC-G deficiency increases susceptibility to develop B-cell lymphoproliferative disorders.

Simonetti G, Bertilaccio MT, Rodriguez TV, Apollonio B, Dagklis A, Rocchi M, Innocenzi A, Casola S, Winkler TH, Nitschke L, Ponzoni M, Caligaris-Cappio F, Ghia P.

Haematologica. 2014 Aug;99(8):1356-64. doi: 10.3324/haematol.2013.100230. Epub 2014 May 23.

6.

Monoclonal B-cell lymphocytosis in healthy blood donors: an unexpectedly common finding.

Shim YK, Rachel JM, Ghia P, Boren J, Abbasi F, Dagklis A, Venable G, Kang J, Degheidy H, Plapp FV, Vogt RF, Menitove JE, Marti GE.

Blood. 2014 Feb 27;123(9):1319-26. doi: 10.1182/blood-2013-08-523704. Epub 2013 Dec 17.

7.

Immunogenetics shows that not all MBL are equal: the larger the clone, the more similar to CLL.

Vardi A, Dagklis A, Scarfò L, Jelinek D, Newton D, Bennett F, Almeida J, Rodriguez-Caballero A, Allgood S, Lanasa M, Cortelezzi A, Orlandi E, Veronese S, Montillo M, Rawstron A, Shanafelt T, Orfao A, Stamatopoulos K, Ghia P.

Blood. 2013 May 30;121(22):4521-8. doi: 10.1182/blood-2012-12-471698. Epub 2013 Apr 17.

8.

Bone marrow histopathology in the diagnostic evaluation of splenic marginal-zone and splenic diffuse red pulp small B-cell lymphoma: a reliable substitute for spleen histopathology?

Ponzoni M, Kanellis G, Pouliou E, Baliakas P, Scarfò L, Ferreri AJ, Doglioni C, Bikos V, Dagklis A, Anagnostopoulos A, Ghia P, Stamatopoulos K, Papadaki T.

Am J Surg Pathol. 2012 Nov;36(11):1609-18. doi: 10.1097/PAS.0b013e318271243d.

PMID:
23073320
9.

Selection of antigen receptors in splenic marginal-zone lymphoma: further support from the analysis of the immunoglobulin light-chain gene repertoire.

Bikos V, Stalika E, Baliakas P, Darzentas N, Davis Z, Traverse-Glehen A, Dagklis A, Kanellis G, Anagnostopoulos A, Tsaftaris A, Ponzoni M, Berger F, Felman P, Ghia P, Papadaki T, Oscier D, Belessi C, Stamatopoulos K.

Leukemia. 2012 Dec;26(12):2567-9. doi: 10.1038/leu.2012.207. Epub 2012 Jun 18. No abstract available.

PMID:
22858907
10.

KAP1 regulates gene networks controlling mouse B-lymphoid cell differentiation and function.

Santoni de Sio FR, Massacand J, Barde I, Offner S, Corsinotti A, Kapopoulou A, Bojkowska K, Dagklis A, Fernandez M, Ghia P, Thomas JH, Pinschewer D, Harris N, Trono D.

Blood. 2012 May 17;119(20):4675-85. doi: 10.1182/blood-2011-12-401117. Epub 2012 Mar 27.

11.

KIBRA gene methylation is associated with unfavorable biological prognostic parameters in chronic lymphocytic leukemia.

Shinawi T, Hill V, Dagklis A, Baliakas P, Stamatopoulos K, Agathanggelou A, Stankovic T, Maher ER, Ghia P, Latif F.

Epigenetics. 2012 Mar;7(3):211-5. doi: 10.4161/epi.7.3.19222.

PMID:
22430796
12.

Over 30% of patients with splenic marginal zone lymphoma express the same immunoglobulin heavy variable gene: ontogenetic implications.

Bikos V, Darzentas N, Hadzidimitriou A, Davis Z, Hockley S, Traverse-Glehen A, Algara P, Santoro A, Gonzalez D, Mollejo M, Dagklis A, Gangemi F, Bosler DS, Bourikas G, Anagnostopoulos A, Tsaftaris A, Iannitto E, Ponzoni M, Felman P, Berger F, Belessi C, Ghia P, Papadaki T, Dogan A, Degano M, Matutes E, Piris MA, Oscier D, Stamatopoulos K.

Leukemia. 2012 Jul;26(7):1638-46. doi: 10.1038/leu.2012.3. Epub 2012 Jan 6.

PMID:
22222599
13.

Immunoglobulin gene repertoire in ocular adnexal lymphomas: hints on the nature of the antigenic stimulation.

Dagklis A, Ponzoni M, Govi S, Cangi MG, Pasini E, Charlotte F, Vino A, Doglioni C, Davì F, Lossos IS, Ntountas I, Papadaki T, Dolcetti R, Ferreri AJ, Stamatopoulos K, Ghia P.

Leukemia. 2012 Apr;26(4):814-21. doi: 10.1038/leu.2011.276. Epub 2011 Oct 25.

PMID:
22024723
14.

Partial versus productive immunoglobulin heavy locus rearrangements in chronic lymphocytic leukemia: implications for B-cell receptor stereotypy.

Tsakou E, Agathangelidis A, Boudjoghra M, Raff T, Dagklis A, Chatzouli M, Smilevska T, Bourikas G, Merle-Beral H, Manioudaki-Kavallieratou E, Anagnostopoulos A, Brüggemann M, Davi F, Stamatopoulos K, Belessi C.

Mol Med. 2012 Feb 10;18:138-45. doi: 10.2119/molmed.2011.00216. Erratum in: Mol Med. 2013;19:332. Agathagelidis, Andreas [corrected to Agathangelidis, Andreas].

15.

General population low-count CLL-like MBL persists over time without clinical progression, although carrying the same cytogenetic abnormalities of CLL.

Fazi C, Scarfò L, Pecciarini L, Cottini F, Dagklis A, Janus A, Talarico A, Scielzo C, Sala C, Toniolo D, Caligaris-Cappio F, Ghia P.

Blood. 2011 Dec 15;118(25):6618-25. doi: 10.1182/blood-2011-05-357251. Epub 2011 Aug 29.

16.

Is there a role for antigen selection in mantle cell lymphoma? Immunogenetic support from a series of 807 cases.

Hadzidimitriou A, Agathangelidis A, Darzentas N, Murray F, Delfau-Larue MH, Pedersen LB, Lopez AN, Dagklis A, Rombout P, Beldjord K, Kolstad A, Dreyling MH, Anagnostopoulos A, Tsaftaris A, Mavragani-Tsipidou P, Rosenwald A, Ponzoni M, Groenen P, Ghia P, Sander B, Papadaki T, Campo E, Geisler C, Rosenquist R, Davi F, Pott C, Stamatopoulos K.

Blood. 2011 Sep 15;118(11):3088-95. doi: 10.1182/blood-2011-03-343434. Epub 2011 Jul 26.

17.

Lack of TIR8/SIGIRR triggers progression of chronic lymphocytic leukemia in mouse models.

Bertilaccio MT, Simonetti G, Dagklis A, Rocchi M, Rodriguez TV, Apollonio B, Mantovani A, Ponzoni M, Ghia P, Garlanda C, Caligaris-Cappio F, Muzio M.

Blood. 2011 Jul 21;118(3):660-9. doi: 10.1182/blood-2011-01-329870. Epub 2011 Jun 7. Erratum in: Blood. 2012 Sep 27;120(13):2773.

18.

Monoclonal B cell lymphocytosis in hepatitis C virus infected individuals.

Fazi C, Dagklis A, Cottini F, Scarfò L, Bertilaccio MT, Finazzi R, Memoli M, Ghia P.

Cytometry B Clin Cytom. 2010;78 Suppl 1:S61-8. doi: 10.1002/cyto.b.20545.

19.

CLL-like monoclonal B-cell lymphocytosis: are we all bound to have it?

Scarfò L, Dagklis A, Scielzo C, Fazi C, Ghia P.

Semin Cancer Biol. 2010 Dec;20(6):384-90. doi: 10.1016/j.semcancer.2010.08.005. Epub 2010 Sep 15. Review.

PMID:
20816789
20.

HS1 has a central role in the trafficking and homing of leukemic B cells.

Scielzo C, Bertilaccio MT, Simonetti G, Dagklis A, ten Hacken E, Fazi C, Muzio M, Caiolfa V, Kitamura D, Restuccia U, Bachi A, Rocchi M, Ponzoni M, Ghia P, Caligaris-Cappio F.

Blood. 2010 Nov 4;116(18):3537-46. doi: 10.1182/blood-2009-12-258814. Epub 2010 Jun 8.

21.

Activation-induced cytidine deaminase splicing patterns in chronic lymphocytic leukemia.

Marantidou F, Dagklis A, Stalika E, Korkolopoulou P, Saetta A, Anagnostopoulos A, Laoutaris N, Stamatopoulos K, Belessi C, Scouras Z, Patsouris E.

Blood Cells Mol Dis. 2010 Apr 15;44(4):262-7. doi: 10.1016/j.bcmd.2009.12.005. Epub 2010 Feb 8. Erratum in: Blood Cells Mol Dis. 2010 Aug 15;45(2):180. Korkolopoulou, Panagiota [corrected to Korkolopoulou, Penelope].

PMID:
20117026
22.

Monoclonal B lymphocytosis in the general population.

Dagklis A, Fazi C, Scarfo L, Apollonio B, Ghia P.

Leuk Lymphoma. 2009 Mar;50(3):490-2. doi: 10.1080/10428190902763475.

PMID:
19347732
23.

The immunoglobulin gene repertoire of low-count chronic lymphocytic leukemia (CLL)-like monoclonal B lymphocytosis is different from CLL: diagnostic implications for clinical monitoring.

Dagklis A, Fazi C, Sala C, Cantarelli V, Scielzo C, Massacane R, Toniolo D, Caligaris-Cappio F, Stamatopoulos K, Ghia P.

Blood. 2009 Jul 2;114(1):26-32. doi: 10.1182/blood-2008-09-176933. Epub 2008 Nov 24.

24.

A woman and her canary: a tale of chlamydiae and lymphomas.

Ferreri AJ, Dolcetti R, Magnino S, Doglioni C, Cangi MG, Pecciarini L, Ghia P, Dagklis A, Pasini E, Vicari N, Dognini GP, Resti AG, Ponzoni M.

J Natl Cancer Inst. 2007 Sep 19;99(18):1418-9. Epub 2007 Sep 11. No abstract available.

PMID:
17848672

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