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Items: 8

1.

Selective inhibition of TGFβ1 activation overcomes primary resistance to checkpoint blockade therapy by altering tumor immune landscape.

Martin CJ, Datta A, Littlefield C, Kalra A, Chapron C, Wawersik S, Dagbay KB, Brueckner CT, Nikiforov A, Danehy FT Jr, Streich FC Jr, Boston C, Simpson A, Jackson JW, Lin S, Danek N, Faucette RR, Raman P, Capili AD, Buckler A, Carven GJ, Schürpf T.

Sci Transl Med. 2020 Mar 25;12(536). pii: eaay8456. doi: 10.1126/scitranslmed.aay8456.

PMID:
32213632
2.

Structural basis for specific inhibition of extracellular activation of pro- or latent myostatin by the monoclonal antibody SRK-015.

Dagbay KB, Treece E, Streich FC Jr, Jackson JW, Faucette RR, Nikiforov A, Lin SC, Boston CJ, Nicholls SB, Capili AD, Carven GJ.

J Biol Chem. 2020 Feb 19. pii: jbc.RA119.012293. doi: 10.1074/jbc.RA119.012293. [Epub ahead of print]

3.

Chemoproteomics Using Nucleotide Acyl Phosphates Reveals an ATP Binding Site at the Dimer Interface of Procaspase-6.

Okerberg ES, Dagbay KB, Green JL, Soni I, Aban A, Nomanbhoy TK, Savinov SN, Hardy JA, Kozarich JW.

Biochemistry. 2019 Dec 31;58(52):5320-5328. doi: 10.1021/acs.biochem.9b00290. Epub 2019 May 24.

4.

Multiple Mechanisms of Zinc-Mediated Inhibition for the Apoptotic Caspases-3, -6, -7, and -8.

Eron SJ, MacPherson DJ, Dagbay KB, Hardy JA.

ACS Chem Biol. 2018 May 18;13(5):1279-1290. doi: 10.1021/acschembio.8b00064. Epub 2018 Apr 11.

5.

Multiple proteolytic events in caspase-6 self-activation impact conformations of discrete structural regions.

Dagbay KB, Hardy JA.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):E7977-E7986. doi: 10.1073/pnas.1704640114. Epub 2017 Sep 1.

6.

Tumor-Associated Mutations in Caspase-6 Negatively Impact Catalytic Efficiency.

Dagbay KB, Hill ME, Barrett E, Hardy JA.

Biochemistry. 2017 Aug 29;56(34):4568-4577. doi: 10.1021/acs.biochem.7b00357. Epub 2017 Aug 16.

7.

Caspase-6 Undergoes a Distinct Helix-Strand Interconversion upon Substrate Binding.

Dagbay KB, Bolik-Coulon N, Savinov SN, Hardy JA.

J Biol Chem. 2017 Mar 24;292(12):4885-4897. doi: 10.1074/jbc.M116.773499. Epub 2017 Feb 2.

8.

Factors affecting degradation of polyethylene terephthalate (PET) during pre-flotation conditioning.

Caparanga AR, Basilia BA, Dagbay KB, Salvacion JW.

Waste Manag. 2009 Sep;29(9):2425-8. doi: 10.1016/j.wasman.2009.03.025. Epub 2009 Apr 25.

PMID:
19394808

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