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Nasopharyngeal carriage of invasive pneumococcal serotypes during childhood community-acquired alveolar pneumonia is associated with specific clinical presentation.

Faingelernt Y, Dagan R, Givon-Lavi N, Ben-Shimol S, Bar-Ziv J, Greenberg D.

J Infect Dis. 2019 Oct 5. pii: jiz513. doi: 10.1093/infdis/jiz513. [Epub ahead of print]


Proton therapy following induction chemotherapy for pediatric and adolescent nasopharyngeal carcinoma.

Uezono H, Indelicato DJ, Rotondo RL, Sandler ES, Katzenstein HM, Dagan R, Mendenhall WM, Mailhot Vega R, Brennan BM, Bradley JA.

Pediatr Blood Cancer. 2019 Sep 16:e27990. doi: 10.1002/pbc.27990. [Epub ahead of print]


Use of Chest Radiography Examination as a Probe for PCV Impact on Lower Respiratory Tract Infections in Young Children.

Ben-Shimol S, Dagan R, Givon-Lavi N, Avital D, Bar-Ziv J, Greenberg D.

Clin Infect Dis. 2019 Aug 15. pii: ciz768. doi: 10.1093/cid/ciz768. [Epub ahead of print]


Stable dynamics of pneumococcal carriage over a decade in the pre-PCV era.

Wagner BG, Althouse BM, Givon-Lavi N, Hu H, Dagan R.

Vaccine. 2019 Sep 3;37(37):5625-5629. doi: 10.1016/j.vaccine.2019.07.077. Epub 2019 Aug 2.


In regards to Orlandi et al HED-19-0487.

Dagan R, Bryant C.

Head Neck. 2019 Oct;41(10):3736. doi: 10.1002/hed.25854. Epub 2019 Jul 17. No abstract available.


Interaction With Nontypeable Haemophilus influenzae Alters Progression of Streptococcus pneumoniae From Colonization to Disease in a Site-Specific Manner.

Lewnard JA, Givon-Lavi N, Dagan R.

J Infect Dis. 2019 Sep 13;220(8):1367-1376. doi: 10.1093/infdis/jiz312.


Relationship between immune response to pneumococcal conjugate vaccines in infants and indirect protection after vaccine implementation.

Dagan R.

Expert Rev Vaccines. 2019 Jun;18(6):641-661. doi: 10.1080/14760584.2019.1627207. Epub 2019 Jun 22.


Hospital-onset adult invasive pneumococcal disease in Israel: Sicker patients, different pathogens.

Kenig A, Regev-Yochay G, Khakshoor S, Cohen-Poradosu R, Bishara J, Glikman D, Hershman-Sarafov M, Dagan R, Zimhony O; IAIPD Research Group.

Int J Infect Dis. 2019 Aug;85:195-202. doi: 10.1016/j.ijid.2019.06.013. Epub 2019 Jun 18.


Pinch-Off Formation in Monolayer and Multilayers MoS2 Field-Effect Transistors.

Vaknin Y, Dagan R, Rosenwaks Y.

Nanomaterials (Basel). 2019 Jun 14;9(6). pii: E882. doi: 10.3390/nano9060882.


Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study.

Lo SW, Gladstone RA, van Tonder AJ, Lees JA, du Plessis M, Benisty R, Givon-Lavi N, Hawkins PA, Cornick JE, Kwambana-Adams B, Law PY, Ho PL, Antonio M, Everett DB, Dagan R, von Gottberg A, Klugman KP, McGee L, Breiman RF, Bentley SD; Global Pneumococcal Sequencing Consortium.

Lancet Infect Dis. 2019 Jul;19(7):759-769. doi: 10.1016/S1473-3099(19)30297-X. Epub 2019 Jun 10.


Putative novel cps loci in a large global collection of pneumococci.

van Tonder AJ, Gladstone RA, Lo SW, Nahm MH, du Plessis M, Cornick J, Kwambana-Adams B, Madhi SA, Hawkins PA, Benisty R, Dagan R, Everett D, Antonio M, Klugman KP, von Gottberg A, Breiman RF, McGee L, Bentley SD, The Global Pneumococcal Sequencing Consortium.

Microb Genom. 2019 Jul;5(7). doi: 10.1099/mgen.0.000274. Epub 2019 Jun 11.


Incidence of respiratory syncytial virus bronchiolitis in hospitalized infants born at 33-36 weeks of gestational age compared with those born at term: a retrospective cohort study.

Greenberg D, Dagan R, Shany E, Ben-Shimol S, Givon-Lavi N.

Clin Microbiol Infect. 2019 Jun 7. pii: S1198-743X(19)30288-5. doi: 10.1016/j.cmi.2019.05.025. [Epub ahead of print]


Rapid Clearance Profile of Plasma Circulating Tumor HPV Type 16 DNA during Chemoradiotherapy Correlates with Disease Control in HPV-Associated Oropharyngeal Cancer.

Chera BS, Kumar S, Beaty BT, Marron D, Jefferys S, Green R, Goldman EC, Amdur R, Sheets N, Dagan R, Hayes DN, Weiss J, Grilley-Olson JE, Zanation A, Hackman T, Blumberg JM, Patel S, Weissler M, Tan XM, Parker JS, Mendenhall W, Gupta GP.

Clin Cancer Res. 2019 Aug 1;25(15):4682-4690. doi: 10.1158/1078-0432.CCR-19-0211. Epub 2019 May 14.


International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact.

Gladstone RA, Lo SW, Lees JA, Croucher NJ, van Tonder AJ, Corander J, Page AJ, Marttinen P, Bentley LJ, Ochoa TJ, Ho PL, du Plessis M, Cornick JE, Kwambana-Adams B, Benisty R, Nzenze SA, Madhi SA, Hawkins PA, Everett DB, Antonio M, Dagan R, Klugman KP, von Gottberg A, McGee L, Breiman RF, Bentley SD; Global Pneumococcal Sequencing Consortium.

EBioMedicine. 2019 May;43:338-346. doi: 10.1016/j.ebiom.2019.04.021. Epub 2019 Apr 16.


Isolated leptomeningeal progression from sinonasal carcinomas: Implications for staging workup and treatment.

Dagan R, Bryant CM, Mendenhall WM, Amdur RJ, Morris CG, Lanza DC, Dziegielewski PT, Justice JM, Lobo BC, Silver NL, Fernandes R, Bunnell A, Guthrie T, Gopalan PK, Rahman M, Tavanaiepour D.

Head Neck. 2019 Aug;41(8):2647-2654. doi: 10.1002/hed.25741. Epub 2019 Mar 25.


Streptococcus pneumoniae Cell Wall-Localized Trigger Factor Elicits a Protective Immune Response and Contributes to Bacterial Adhesion to the Host.

Cohen A, Troib S, Dotan S, Najmuldeen H, Yesilkaya H, Kushnir T, Shagan M, Portnoi M, Nachmani H, Benisty R, Tal M, Ellis R, Chalifa-Caspi V, Dagan R, Nebenzahl YM.

Sci Rep. 2019 Mar 12;9(1):4295. doi: 10.1038/s41598-019-40779-0.


Oligometastatic squamous cell carcinoma of the head and neck treated with stereotactic body ablative radiotherapy: Single-institution outcomes.

Bates JE, De Leo AN, Morris CG, Amdur RJ, Dagan R.

Head Neck. 2019 Jul;41(7):2309-2314. doi: 10.1002/hed.25695. Epub 2019 Feb 20.


An in-silico quality assurance study of contouring target volumes in thoracic tumors within a cooperative group setting.

Elhalawani H, Elgohari B, Lin TA, Mohamed ASR, Fitzgerald TJ, Laurie F, Ulin K, Kalpathy-Cramer J, Guerrero T, Holliday EB, Russo G, Patel A, Jones W, Walker GV, Awan M, Choi M, Dagan R, Mahmoud O, Shapiro A, Kong FS, Gomez D, Zeng J, Decker R, Spoelstra FOB, Gaspar LE, Kachnic LA, Thomas CR Jr, Okunieff P, Fuller CD.

Clin Transl Radiat Oncol. 2019 Jan 6;15:83-92. doi: 10.1016/j.ctro.2019.01.001. eCollection 2019 Feb.


Can CT imaging improve targeting accuracy in clip-based proton therapy of ocular melanoma?

Slopsema RL, Mamalui M, Bolling J, Flampouri S, Yeung D, Li Z, Rutenberg MS, Dagan R.

Phys Med Biol. 2019 Jan 24;64(3):035010. doi: 10.1088/1361-6560/aaf9c9.


Shoulder symptoms and quality of life impact of limited neck dissection after de-intensified chemoradiotherapy: Secondary analysis of two prospective trials.

Wang K, Moon DH, Amdur RJ, Dagan R, Sheets NC, Shen CJ, Green R, Patel SN, Zanation AM, Thorp BD, Hackman TG, Weissler MC, Mendenhall WM, Chera BS.

Head Neck. 2019 May;41(5):1213-1219. doi: 10.1002/hed.25535. Epub 2018 Dec 15.


Studying PCV impact on clinical presentation of otitis media helps to understand its pathogenesis.

Ben-Shimol S, Givon-Lavi N, Leibovitz E, Greenberg D, Dagan R.

Vaccine. 2019 Jan 3;37(1):1-6. doi: 10.1016/j.vaccine.2018.11.054. Epub 2018 Nov 26.


Impact of pneumococcal conjugate vaccines introduction on antibiotic resistance of Streptococcus pneumoniae meningitis in children aged 5 years or younger, Israel, 2004 to 2016.

Ben-Shimol S, Givon-Lavi N, Greenberg D, Stein M, Megged O, Bar-Yochai A, Negari S, Dagan R, On Behalf Of The Israel Bacteremia And Meningitis Active Surveillance Group.

Euro Surveill. 2018 Nov;23(47). doi: 10.2807/1560-7917.ES.2018.23.47.1800081. No abstract available.


Association Between the Decline in Pneumococcal Disease in Unimmunized Adults and Vaccine-Derived Protection Against Colonization in Toddlers and Preschool-Aged Children.

Weinberger DM, Pitzer VE, Regev-Yochay G, Givon-Lavi N, Dagan R.

Am J Epidemiol. 2019 Jan 1;188(1):160-168. doi: 10.1093/aje/kwy219.


Radiation Oncology for Head and Neck Cancer: Current Standards and Future Changes.

Mendenhall WM, Dagan R, Bryant CM, Fernandes RP.

Oral Maxillofac Surg Clin North Am. 2019 Feb;31(1):31-38. doi: 10.1016/j.coms.2018.08.003. Epub 2018 Oct 25. Review.


First Otitis Media and Pneumococcal Conjugate Vaccine Serotypes in Infants.

Dagan R, Pelton S, Bakaletz L, Cohen R.

Pediatr Infect Dis J. 2018 Dec;37(12):e351-e352. doi: 10.1097/INF.0000000000002030. No abstract available.


Quality of Life for Patients With Favorable-Risk HPV-Associated Oropharyngeal Cancer After De-intensified Chemoradiotherapy.

Pearlstein KA, Wang K, Amdur RJ, Shen CJ, Dagan R, Weiss J, Grilley-Olson JE, Zanation A, Hackman TG, Thorp BD, Blumberg JM, Patel S, Sheets N, Weissler MC, Mendenhall WM, Chera BS.

Int J Radiat Oncol Biol Phys. 2019 Mar 1;103(3):646-653. doi: 10.1016/j.ijrobp.2018.10.033. Epub 2018 Nov 2.


Understanding the evolution of antibiotic-nonsusceptible pneumococcal nasopharyngeal colonization following pneumococcal conjugate vaccines implementation in young children.

Danino D, Givon-Lavi N, Ben-Shimol S, Greenberg D, Dagan R.

Clin Infect Dis. 2018 Oct 29. doi: 10.1093/cid/ciy926. [Epub ahead of print]


Maternal Education Is Inversely Related to Vaccination Delay among Infants and Toddlers.

Hazan G, Dagan R, Friger M.

J Pediatr. 2019 Feb;205:120-125.e2. doi: 10.1016/j.jpeds.2018.09.030. Epub 2018 Oct 16.


The relative invasive disease potential of Streptococcus pneumoniae among children after PCV introduction: A systematic review and meta-analysis.

Balsells E, Dagan R, Yildirim I, Gounder PP, Steens A, Muñoz-Almagro C, Mameli C, Kandasamy R, Givon Lavi N, Daprai L, van der Ende A, Trzciński K, Nzenze SA, Meiring S, Foster D, Bulkow LR, Rudolph K, Valero-Rello A, Ducker S, Vestrheim DF, von Gottberg A, Pelton SI, Zuccotti G, Pollard AJ, Sanders EAM, Campbell H, Madhi SA, Nair H, Kyaw MH.

J Infect. 2018 Nov;77(5):368-378. doi: 10.1016/j.jinf.2018.06.004. Epub 2018 Jun 30.


Pneumococcal Meningitis in Adults after Introduction of PCV7 and PCV13, Israel, July 2009-June 20151.

Regev-Yochay G, Reisenberg K, Katzir M, Wiener-Well Y, Rahav G, Strahilevitz J, Istomin V, Tsyba E, Peretz A, Khakshoor S, Dagan R; Israeli Adult Invasive Pneumococcal Disease Group.

Emerg Infect Dis. 2018 Jul;24(7):1275-1284. doi: 10.3201/eid2407.170721.


On King Saul, Two Missing Mules, and Kingella kingae: The Serendipitous Discovery of a Pediatric Pathogen.

Yagupsky P, Dagan R.

Pediatr Infect Dis J. 2018 Dec;37(12):1264-1266. doi: 10.1097/INF.0000000000002110.


Dynamics of Severe and Non-severe Invasive Pneumococcal Disease in Young Children in Israel Following PCV7/PCV13 Introduction.

Glikman D, Dagan R, Barkai G, Averbuch D, Guri A, Givon-Lavi N, Ben-Shimol S; Israel Bacteremia and Meningitis Active Surveillance Group.

Pediatr Infect Dis J. 2018 Oct;37(10):1048-1053. doi: 10.1097/INF.0000000000002100.


A toddler PCV booster dose following 3 infancy priming doses increases circulating serotype-specific IGG levels but does not increase protection against carriage.

Dagan R, Ben-Shimol S, Simell B, Greenberg D, Porat N, Käyhty H, Givon-Lavi N.

Vaccine. 2018 May 11;36(20):2774-2782. doi: 10.1016/j.vaccine.2018.04.007. Epub 2018 Apr 11.


Emergence of Streptococcus pneumoniae Serotype 12F after Sequential Introduction of 7- and 13-Valent Vaccines, Israel.

Rokney A, Ben-Shimol S, Korenman Z, Porat N, Gorodnitzky Z, Givon-Lavi N, Ron M, Agmon V, Dagan R, Valinsky L.

Emerg Infect Dis. 2018 Mar;24(3):453-461. doi: 10.3201/eid2403.170769.


Pneumococcal Phenotype and Interaction with Nontypeable Haemophilus influenzae as Determinants of Otitis Media Progression.

Lewnard JA, Givon-Lavi N, Tähtinen PA, Dagan R.

Infect Immun. 2018 May 22;86(6). pii: e00727-17. doi: 10.1128/IAI.00727-17. Print 2018 Jun.


Flavin Reductase Contributes to Pneumococcal Virulence by Protecting from Oxidative Stress and Mediating Adhesion and Elicits Protection Against Pneumococcal Challenge.

Morozov GI, Porat N, Kushnir T, Najmuldeen H, Adawi A, Chalifa-Caspi V, Benisty R, Ohayon A, Liron O, Azriel S, Malka I, Dotan S, Portnoi M, Piotrowski AA, Kafka D, Hajaj B, Fishilevich T, Shagan M, Tal M, Ellis R, Morrison DA, Mitchell AM, Mitchell TJ, Dagan R, Yesilkaya H, Nebenzahl YM.

Sci Rep. 2018 Jan 10;8(1):314. doi: 10.1038/s41598-017-18645-8.


Serotype-specific immune responses to pneumococcal conjugate vaccine among children are significantly correlated by individual: Analysis of randomized controlled trial data.

Lipsitch M, Li LM, Patterson S, Trammel J, Juergens C, Gruber WC, Scott DA, Dagan R.

Vaccine. 2018 Jan 25;36(4):473-478. doi: 10.1016/j.vaccine.2017.12.015. Epub 2017 Dec 14.


Nitric oxide inhalations in bronchiolitis: A pilot, randomized, double-blinded, controlled trial.

Tal A, Greenberg D, Av-Gay Y, Golan-Tripto I, Feinstein Y, Ben-Shimol S, Dagan R, Goldbart AD.

Pediatr Pulmonol. 2018 Jan;53(1):95-102. doi: 10.1002/ppul.23905. Epub 2017 Nov 27.


Patterns of Progression in Metastatic Estrogen Receptor Positive Breast Cancer: An Argument for Local Therapy.

Kelly P, Ma Z, Baidas S, Moroose R, Shah N, Dagan R, Mamounas E, Rineer J.

Int J Breast Cancer. 2017;2017:1367159. doi: 10.1155/2017/1367159. Epub 2017 Sep 25.


Pan-serotype Reduction in Progression of Streptococcus pneumoniae to Otitis Media After Rollout of Pneumococcal Conjugate Vaccines.

Lewnard JA, Givon-Lavi N, Weinberger DM, Lipsitch M, Dagan R.

Clin Infect Dis. 2017 Nov 13;65(11):1853-1861. doi: 10.1093/cid/cix673.


Reply to Nevens et al.

Amdur RJ, Dagan R, Mendenhall WM.

Radiother Oncol. 2017 Aug;124(2):335. doi: 10.1016/j.radonc.2017.03.024. Epub 2017 Jul 7. No abstract available.


Comparative incidence dynamics and serotypes of meningitis, bacteremic pneumonia and other-IPD in young children in the PCV era: Insights from Israeli surveillance studies.

Ben-Shimol S, Givon-Lavi N, Grisaru-Soen G, Megged O, Greenberg D, Dagan R; Israel Bacteremia and Meningitis Active Surveillance Group.

Vaccine. 2018 Aug 28;36(36):5477-5484. doi: 10.1016/j.vaccine.2017.05.059. Epub 2017 Jun 1.


Stereotactic body radiation therapy for oligoprogression of metastatic disease from gastrointestinal cancers: A novel approach to extend chemotherapy efficacy.

Wray J, Hawamdeh RF, Hasija N, Dagan R, Yeung AR, Lightsey JL, Okunieff P, Daily KC, George TJ, Zlotecki RA, Trevino J, Dang LH.

Oncol Lett. 2017 Mar;13(3):1087-1094. doi: 10.3892/ol.2016.5540. Epub 2016 Dec 27.


The herd effects of infant PCV7/PCV13 sequential implementation on adult invasive pneumococcal disease, six years post implementation; a nationwide study in Israel.

Regev-Yochay G, Katzir M, Strahilevitz J, Rahav G, Finn T, Miron D, Maor Y, Chazan B, Schindler Y, Dagan R; IAIPD group.

Vaccine. 2017 Apr 25;35(18):2449-2456. doi: 10.1016/j.vaccine.2017.03.031. Epub 2017 Mar 22.


Preoperative Protective Endovascular Covered Stent Placement Followed by Surgery for Management of the Cervical Common and Internal Carotid Arteries with Tumor Encasement.

Markiewicz MR, Pirgousis P, Bryant C, Cunningham JC, Dagan R, Sandhu SJ, Siragusa DA, Gopinath A, Fernandes R.

J Neurol Surg B Skull Base. 2017 Feb;78(1):52-58. doi: 10.1055/s-0036-1584298. Epub 2016 Jun 20.


A multinational report of technical factors on stereotactic body radiotherapy for oligometastases.

Redmond KJ, Lo SS, Dagan R, Poon I, Foote MC, Erler D, Lee Y, Lohr F, Biswas T, Ricardi U, Sahgal A.

Future Oncol. 2017 May;13(12):1081-1089. doi: 10.2217/fon-2016-0479. Epub 2017 Feb 3.


PCV13-vaccinated children still carrying PCV13 additional serotypes show similar carriage density to a control group of PCV7-vaccinated children.

Dagan R, Juergens C, Trammel J, Patterson S, Greenberg D, Givon-Lavi N, Porat N, Gruber WC, Scott DA.

Vaccine. 2017 Feb 7;35(6):945-950. doi: 10.1016/j.vaccine.2016.12.052. Epub 2017 Jan 11.


Nasopharyngeal Pneumococcal Carriage During Childhood Community-Acquired Alveolar Pneumonia: Relationship Between Specific Serotypes and Coinfecting Viruses.

Greenberg D, Givon-Lavi N, Faingelernt Y, Ben-Shimol S, Avni YS, Bar-Ziv J, Dagan R.

J Infect Dis. 2017 Apr 1;215(7):1111-1116. doi: 10.1093/infdis/jiw613.


Cocontribution of Rotavirus and Pneumococcal Conjugate Vaccines to the Reduction of Pediatric Hospital Visits in Young Children.

Ben-Shimol S, Givon-Lavi N, Greenberg D, Dagan R.

J Pediatr. 2017 Mar;182:253-259.e2. doi: 10.1016/j.jpeds.2016.11.041. Epub 2016 Dec 8.


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