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Items: 17

1.

Thioredoxin-1 confines T cell alloresponse and pathogenicity in graft-versus-host disease.

Sofi MH, Wu Y, Schutt SD, Dai M, Daenthanasanmak A, Heinrichs Voss J, Nguyen H, Bastian D, Iamsawat S, Selvam SP, Liu C, Maulik N, Ogretmen B, Jin J, Mehrotra S, Yu XZ.

J Clin Invest. 2019 May 2;129(8):2760-2774. doi: 10.1172/JCI122899.

2.

Complement C3a and C5a receptors promote GVHD by suppressing mitophagy in recipient dendritic cells.

Nguyen H, Kuril S, Bastian D, Kim J, Zhang M, Vaena SG, Dany M, Dai M, Heinrichs JL, Daenthanasanmak A, Iamsawat S, Schutt S, Fu J, Wu Y, Fairlie DP, Atkinson C, Ogretmen B, Tomlinson S, Yu XZ.

JCI Insight. 2018 Dec 20;3(24). pii: 121697. doi: 10.1172/jci.insight.121697.

3.

Targeting Sirt-1 controls GVHD by inhibiting T-cell allo-response and promoting Treg stability in mice.

Daenthanasanmak A, Iamsawat S, Chakraborty P, Nguyen HD, Bastian D, Liu C, Mehrotra S, Yu XZ.

Blood. 2019 Jan 17;133(3):266-279. doi: 10.1182/blood-2018-07-863233. Epub 2018 Dec 4.

PMID:
30514750
4.

Targeting PIM Kinase with PD1 Inhibition Improves Immunotherapeutic Antitumor T-cell Response.

Chatterjee S, Chakraborty P, Daenthanasanmak A, Iamsawat S, Andrejeva G, Luevano LA, Wolf M, Baliga U, Krieg C, Beeson CC, Mehrotra M, Hill EG, Rathmell JC, Yu XZ, Kraft AS, Mehrotra S.

Clin Cancer Res. 2019 Feb 1;25(3):1036-1049. doi: 10.1158/1078-0432.CCR-18-0706. Epub 2018 Oct 16.

PMID:
30327305
5.

Stabilization of Foxp3 by Targeting JAK2 Enhances Efficacy of CD8 Induced Regulatory T Cells in the Prevention of Graft-versus-Host Disease.

Iamsawat S, Daenthanasanmak A, Voss JH, Nguyen H, Bastian D, Liu C, Yu XZ.

J Immunol. 2018 Nov 1;201(9):2812-2823. doi: 10.4049/jimmunol.1800793. Epub 2018 Sep 21.

PMID:
30242073
6.

Inducible T-Cell Co-Stimulator Impacts Chronic Graft-Versus-Host Disease by Regulating Both Pathogenic and Regulatory T Cells.

Zhang M, Wu Y, Bastian D, Iamsawat S, Chang J, Daenthanasanmak A, Nguyen HD, Schutt S, Dai M, Chen F, Suh WK, Yu XZ.

Front Immunol. 2018 Jun 22;9:1461. doi: 10.3389/fimmu.2018.01461. eCollection 2018.

7.

PIM-2 protein kinase negatively regulates T cell responses in transplantation and tumor immunity.

Daenthanasanmak A, Wu Y, Iamsawat S, Nguyen HD, Bastian D, Zhang M, Sofi MH, Chatterjee S, Hill EG, Mehrotra S, Kraft AS, Yu XZ.

J Clin Invest. 2018 Jul 2;128(7):2787-2801. doi: 10.1172/JCI95407. Epub 2018 May 21.

8.

Targeting JAK2 reduces GVHD and xenograft rejection through regulation of T cell differentiation.

Betts BC, Bastian D, Iamsawat S, Nguyen H, Heinrichs JL, Wu Y, Daenthanasanmak A, Veerapathran A, O'Mahony A, Walton K, Reff J, Horna P, Sagatys EM, Lee MC, Singer J, Chang YJ, Liu C, Pidala J, Anasetti C, Yu XZ.

Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1582-1587. doi: 10.1073/pnas.1712452115. Epub 2018 Jan 30.

9.

IL-27 Receptor Signaling on T cells Augments GVHD Severity through Enhancing Th1 Responses.

Bastian D, Liu Y, Wu Y, Schutt S, Nguyen HD, Daenthanasanmak A, Sofi MH, Zhang M, Iamsuwat S, Yu XZ.

J Immunol Res Ther. 2018;3(1):151-157. Epub 2018 Jun 7.

10.

CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response.

Chatterjee S, Daenthanasanmak A, Chakraborty P, Wyatt MW, Dhar P, Selvam SP, Fu J, Zhang J, Nguyen H, Kang I, Toth K, Al-Homrani M, Husain M, Beeson G, Ball L, Helke K, Husain S, Garrett-Mayer E, Hardiman G, Mehrotra M, Nishimura MI, Beeson CC, Bupp MG, Wu J, Ogretmen B, Paulos CM, Rathmell J, Yu XZ, Mehrotra S.

Cell Metab. 2018 Jan 9;27(1):85-100.e8. doi: 10.1016/j.cmet.2017.10.006. Epub 2017 Nov 9.

11.

Ceramide synthesis regulates T cell activity and GVHD development.

Sofi MH, Heinrichs J, Dany M, Nguyen H, Dai M, Bastian D, Schutt S, Wu Y, Daenthanasanmak A, Gencer S, Zivkovic A, Szulc Z, Stark H, Liu C, Chang YJ, Ogretmen B, Yu XZ.

JCI Insight. 2017 May 18;2(10). pii: 91701. doi: 10.1172/jci.insight.91701. eCollection 2017 May 18.

12.

Metabolic reprogramming of alloantigen-activated T cells after hematopoietic cell transplantation.

Nguyen HD, Chatterjee S, Haarberg KM, Wu Y, Bastian D, Heinrichs J, Fu J, Daenthanasanmak A, Schutt S, Shrestha S, Liu C, Wang H, Chi H, Mehrotra S, Yu XZ.

J Clin Invest. 2016 Apr 1;126(4):1337-52. doi: 10.1172/JCI82587. Epub 2016 Mar 7.

13.

Generation of lentivirus-induced dendritic cells under GMP-compliant conditions for adaptive immune reconstitution against cytomegalovirus after stem cell transplantation.

Sundarasetty BS, Kloess S, Oberschmidt O, Naundorf S, Kuehlcke K, Daenthanasanmak A, Gerasch L, Figueiredo C, Blasczyk R, Ruggiero E, Fronza R, Schmidt M, von Kalle C, Rothe M, Ganser A, Koehl U, Stripecke R.

J Transl Med. 2015 Jul 22;13:240. doi: 10.1186/s12967-015-0599-5.

14.

Engineered dendritic cells from cord blood and adult blood accelerate effector T cell immune reconstitution against HCMV.

Daenthanasanmak A, Salguero G, Sundarasetty BS, Waskow C, Cosgun KN, Guzman CA, Riese P, Gerasch L, Schneider A, Ingendoh A, Messerle M, Gabaev I, Woelk B, Ruggiero E, Schmidt M, von Kalle C, Figueiredo C, Eiz-Vesper B, von Kaisenberg C, Ganser A, Stripecke R.

Mol Ther Methods Clin Dev. 2015 Jan 7;1:14060. doi: 10.1038/mtm.2014.60. eCollection 2015.

15.

Dendritic cell-mediated immune humanization of mice: implications for allogeneic and xenogeneic stem cell transplantation.

Salguero G, Daenthanasanmak A, Münz C, Raykova A, Guzmán CA, Riese P, Figueiredo C, Länger F, Schneider A, Macke L, Sundarasetty BS, Witte T, Ganser A, Stripecke R.

J Immunol. 2014 May 15;192(10):4636-47. doi: 10.4049/jimmunol.1302887. Epub 2014 Apr 16.

16.

Integrase-defective lentiviral vectors encoding cytokines induce differentiation of human dendritic cells and stimulate multivalent immune responses in vitro and in vivo.

Daenthanasanmak A, Salguero G, Borchers S, Figueiredo C, Jacobs R, Sundarasetty BS, Schneider A, Schambach A, Eiz-Vesper B, Blasczyk R, Weissinger EM, Ganser A, Stripecke R.

Vaccine. 2012 Jul 20;30(34):5118-31. doi: 10.1016/j.vaccine.2012.05.063. Epub 2012 Jun 9.

17.

Growing bacteria shed elicitors of Drosophila humoral immunity.

Karlsson J, Oldenvi S, Fahlander C, Daenthanasanmak A, Steiner H.

J Innate Immun. 2012;4(1):111-6. doi: 10.1159/000329224. Epub 2011 Aug 9.

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