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Items: 1 to 50 of 149


Radioimmunotherapy of Blastomycosis in a Mouse Model With a (1→3)-β-Glucans Targeting Antibody.

Helal M, Allen KJH, van Dijk B, Nosanchuk JD, Snead E, Dadachova E.

Front Microbiol. 2020 Feb 7;11:147. doi: 10.3389/fmicb.2020.00147. eCollection 2020.


Comparison of various radioactive payloads for a human monoclonal antibody to glycoprotein 41 for elimination of HIV-infected cells.

Garg R, Mills K, Allen KJH, Causey P, Perron RW, Gendron D, Sanche S, Berman JW, Gorny MK, Dadachova E.

Nucl Med Biol. 2020 Feb 19;82-83:80-88. doi: 10.1016/j.nucmedbio.2020.02.009. [Epub ahead of print]


Evaluating the Combination of Radioimmunotherapy and Immunotherapy in a Melanoma Mouse Model.

Jiao R, Allen KJH, Malo ME, Rickles D, Dadachova E.

Int J Mol Sci. 2020 Jan 24;21(3). pii: E773. doi: 10.3390/ijms21030773.


Future Vistas in Alpha Therapy of Infectious Diseases.

Dadachova E.

J Med Imaging Radiat Sci. 2019 Dec;50(4 Suppl 1):S49-S52. doi: 10.1016/j.jmir.2019.06.052. Epub 2019 Aug 16. No abstract available.


Daratumumab-225Actinium conjugate demonstrates greatly enhanced antitumor activity against experimental multiple myeloma tumors.

Dawicki W, Allen KJH, Jiao R, Malo ME, Helal M, Berger MS, Ludwig DL, Dadachova E.

Oncoimmunology. 2019 May 1;8(8):1607673. doi: 10.1080/2162402X.2019.1607673. eCollection 2019.


Detection and targeting insulin growth factor receptor type 2 (IGF2R) in osteosarcoma PDX in mouse models and in canine osteosarcoma tumors.

Karkare S, Allen KJH, Jiao R, Malo ME, Dawicki W, Helal M, Godson DL, Dickinson R, MacDonald-Dickinson V, Yang R, Hoang B, Gorlick R, Geller DS, Dadachova E.

Sci Rep. 2019 Aug 7;9(1):11476. doi: 10.1038/s41598-019-47808-y.


Monoclonal Antibodies Against Human Papillomavirus E6 and E7 Oncoproteins Inhibit Tumor Growth in Experimental Cervical Cancer.

Jiang Z, Albanese J, Kesterson J, Warrick J, Karabakhtsian R, Dadachova E, Phaëton R.

Transl Oncol. 2019 Oct;12(10):1289-1295. doi: 10.1016/j.tranon.2019.06.003. Epub 2019 Jul 17.


Comparative Radioimmunotherapy of Experimental Melanoma with Novel Humanized Antibody to Melanin Labeled with 213Bismuth and 177Lutetium.

Allen KJH, Jiao R, Malo ME, Frank C, Fisher DR, Rickles D, Dadachova E.

Pharmaceutics. 2019 Jul 18;11(7). pii: E348. doi: 10.3390/pharmaceutics11070348.


Evaluation of novel highly specific antibodies to cancer testis antigen Centrin-1 for radioimmunoimaging and radioimmunotherapy of pancreatic cancer.

Jiao R, Allen KJH, Malo ME, Helal M, Jiang Z, Smart K, Buhl SV, Rickles D, Bryan RA, Dadachova E.

Cancer Med. 2019 Sep;8(11):5289-5300. doi: 10.1002/cam4.2379. Epub 2019 Jul 16.


Usefulness of continuous probability distributions of rates for modelling radionuclide biokinetics in humans and animals.

Shuryak I, Dadachova E.

Sci Rep. 2019 Feb 4;9(1):1218. doi: 10.1038/s41598-018-38046-9.


Biodistribution of a Radiolabeled Antibody in Mice as an Approach to Evaluating Antibody Pharmacokinetics.

Allen KJH, Jiao R, Malo ME, Frank C, Dadachova E.

Pharmaceutics. 2018 Dec 5;10(4). pii: E262. doi: 10.3390/pharmaceutics10040262.


Survival and redox activity of Friedmanniomyces endolithicus, an Antarctic endemic black meristematic fungus, after gamma rays exposure.

Pacelli C, Bryan RA, Onofri S, Selbmann L, Zucconi L, Shuryak I, Dadachova E.

Fungal Biol. 2018 Dec;122(12):1222-1227. doi: 10.1016/j.funbio.2018.10.002. Epub 2018 Oct 23.


Radioimmunotherapy as a Novel Approach in HIV, Bacterial, and Fungal Infectious Diseases.

Helal M, Dadachova E.

Cancer Biother Radiopharm. 2018 Oct;33(8):330-335. doi: 10.1089/cbr.2018.2481. Epub 2018 Aug 22. Review.


Responses of the Black Fungus Cryomyces antarcticus to Simulated Mars and Space Conditions on Rock Analogs.

Pacelli C, Selbmann L, Zucconi L, Coleine C, de Vera JP, Rabbow E, Böttger U, Dadachova E, Onofri S.

Astrobiology. 2019 Feb;19(2):209-220. doi: 10.1089/ast.2016.1631. Epub 2018 Aug 1.


Evaluation of N-Succinimidyl S-Acetylthioacetate Ligand for Radiolabeling of Humanized Antibodies with 188Rhenium.

Allen KJH, Jiao R, Malo ME, Dadachova E.

Cancer Biother Radiopharm. 2018 Oct;33(8):349-355. doi: 10.1089/cbr.2018.2480. Epub 2018 Jul 16.


Fungal strategies for dealing with environment- and agriculture-induced stresses.

Rangel DEN, Finlay RD, Hallsworth JE, Dadachova E, Gadd GM.

Fungal Biol. 2018 Jun;122(6):602-612. doi: 10.1016/j.funbio.2018.02.002. Epub 2018 Feb 16. Review.


Resistance of an Antarctic cryptoendolithic black fungus to radiation gives new insights of astrobiological relevance.

Selbmann L, Pacelli C, Zucconi L, Dadachova E, Moeller R, de Vera JP, Onofri S.

Fungal Biol. 2018 Jun;122(6):546-554. doi: 10.1016/j.funbio.2017.10.012. Epub 2017 Nov 4.


Morphological changes in melanized and non-melanized Cryptococcus neoformans cells post exposure to sparsely and densely ionizing radiation demonstrate protective effect of melanin.

Malo ME, Bryan RA, Shuryak I, Dadachova E.

Fungal Biol. 2018 Jun;122(6):449-456. doi: 10.1016/j.funbio.2017.08.010. Epub 2017 Sep 6.


The second International Symposium on Fungal Stress: ISFUS.

Alder-Rangel A, Bailão AM, da Cunha AF, Soares CMA, Wang C, Bonatto D, Dadachova E, Hakalehto E, Eleutherio ECA, Fernandes ÉKK, Gadd GM, Braus GH, Braga GUL, Goldman GH, Malavazi I, Hallsworth JE, Takemoto JY, Fuller KK, Selbmann L, Corrochano LM, von Zeska Kress MR, Bertolini MC, Schmoll M, Pedrini N, Loera O, Finlay RD, Peralta RM, Rangel DEN.

Fungal Biol. 2018 Jun;122(6):386-399. doi: 10.1016/j.funbio.2017.10.011. Epub 2017 Nov 20.


In vivo Evaluation of Free and Chelated Accelerator-produced Actinium- 225 - Radiation Dosimetry and Toxicity Results.

Jiang Z, Revskaya E, Fisher DR, Dadachova E.

Curr Radiopharm. 2018;11(3):215-222. doi: 10.2174/1874471011666180423120707.


Structure-function analysis and therapeutic efficacy of antibodies to fungal melanin for melanoma radioimmunotherapy.

Nosanchuk JD, Jeyakumar A, Ray A, Revskaya E, Jiang Z, Bryan RA, Allen KJH, Jiao R, Malo ME, Gómez BL, Morgenstern A, Bruchertseifer F, Rickles D, Thornton GB, Bowen A, Casadevall A, Dadachova E.

Sci Rep. 2018 Apr 3;8(1):5466. doi: 10.1038/s41598-018-23889-z.


The effect of protracted X-ray exposure on cell survival and metabolic activity of fast and slow growing fungi capable of melanogenesis.

Pacelli C, Bryan RA, Onofri S, Selbmann L, Zucconi L, Shuryak I, Dadachova E.

Environ Microbiol Rep. 2018 Jun;10(3):255-263. doi: 10.1111/1758-2229.12632. Epub 2018 Mar 25.


Spectroelectrochemical Reverse Engineering DemonstratesThat Melanin's Redox and Radical Scavenging Activities Are Linked.

Kim E, Kang M, Tschirhart T, Malo M, Dadachova E, Cao G, Yin JJ, Bentley WE, Wang Z, Payne GF.

Biomacromolecules. 2017 Dec 11;18(12):4084-4098. doi: 10.1021/acs.biomac.7b01166. Epub 2017 Nov 1.


A Radiolabeled Fully Human Antibody to Human Aspartyl (Asparaginyl) β-Hydroxylase Is a Promising Agent for Imaging and Therapy of Metastatic Breast Cancer.

Revskaya E, Jiang Z, Morgenstern A, Bruchertseifer F, Sesay M, Walker S, Fuller S, Lebowitz MS, Gravekamp C, Ghanbari HA, Dadachova E.

Cancer Biother Radiopharm. 2017 Mar;32(2):57-65. doi: 10.1089/cbr.2016.2141.


Melanin, Radiation, and Energy Transduction in Fungi.

Casadevall A, Cordero RJB, Bryan R, Nosanchuk J, Dadachova E.

Microbiol Spectr. 2017 Mar;5(2). doi: 10.1128/microbiolspec.FUNK-0037-2016. Review.


32-Phosphorus selectively delivered by listeria to pancreatic cancer demonstrates a strong therapeutic effect.

Chandra D, Selvanesan BC, Yuan Z, Libutti SK, Koba W, Beck A, Zhu K, Casadevall A, Dadachova E, Gravekamp C.

Oncotarget. 2017 Mar 28;8(13):20729-20740. doi: 10.18632/oncotarget.15117.


Melanin is effective in protecting fast and slow growing fungi from various types of ionizing radiation.

Pacelli C, Bryan RA, Onofri S, Selbmann L, Shuryak I, Dadachova E.

Environ Microbiol. 2017 Apr;19(4):1612-1624. doi: 10.1111/1462-2920.13681. Epub 2017 Feb 22.


Targeted therapy of osteosarcoma with radiolabeled monoclonal antibody to an insulin-like growth factor-2 receptor (IGF2R).

Geller DS, Morris J, Revskaya E, Kahn M, Zhang W, Piperdi S, Park A, Koirala P, Guzik H, Hall C, Hoang B, Yang R, Roth M, Gill J, Gorlick R, Dadachova E.

Nucl Med Biol. 2016 Dec;43(12):812-817. doi: 10.1016/j.nucmedbio.2016.07.008. Epub 2016 Jul 30.


Combination of Antiretroviral Drugs and Radioimmunotherapy Specifically Kills Infected Cells from HIV-Infected Individuals.

Tsukrov D, McFarren A, Morgenstern A, Bruchertseifer F, Dolce E, Gorny MK, Zolla-Pazner S, Berman JW, Schoenbaum E, Zingman BS, Casadevall A, Dadachova E.

Front Med (Lausanne). 2016 Sep 26;3:41. eCollection 2016.


Targeted Radionuclide Therapy of Melanoma.

Norain A, Dadachova E.

Semin Nucl Med. 2016 May;46(3):250-9. doi: 10.1053/j.semnuclmed.2015.12.005. Review.


Quantitative Modeling of Microbial Population Responses to Chronic Irradiation Combined with Other Stressors.

Shuryak I, Dadachova E.

PLoS One. 2016 Jan 25;11(1):e0147696. doi: 10.1371/journal.pone.0147696. eCollection 2016.


Beta emitters rhenium-188 and lutetium-177 are equally effective in radioimmunotherapy of HPV-positive experimental cervical cancer.

Phaeton R, Jiang Z, Revskaya E, Fisher DR, Goldberg GL, Dadachova E.

Cancer Med. 2016 Jan;5(1):9-16. doi: 10.1002/cam4.562. Epub 2015 Dec 2.


A fully human antibody to gp41 selectively eliminates HIV-infected cells that transmigrated across a model human blood brain barrier.

McFarren A, Lopez L, Williams DW, Veenstra M, Bryan RA, Goldsmith A, Morgenstern A, Bruchertseifer F, Zolla-Pazner S, Gorny MK, Eugenin EA, Berman JW, Dadachova E.

AIDS. 2016 Feb 20;30(4):563-72. doi: 10.1097/QAD.0000000000000968.


Structural Characterization of Melanin Pigments from Commercial Preparations of the Edible Mushroom Auricularia auricula.

Prados-Rosales R, Toriola S, Nakouzi A, Chatterjee S, Stark R, Gerfen G, Tumpowsky P, Dadachova E, Casadevall A.

J Agric Food Chem. 2015 Aug 26;63(33):7326-32. doi: 10.1021/acs.jafc.5b02713. Epub 2015 Aug 11.


Targeted radionuclide therapies for pancreatic cancer.

Shah M, Da Silva R, Gravekamp C, Libutti SK, Abraham T, Dadachova E.

Cancer Gene Ther. 2015 Aug;22(8):375-9. doi: 10.1038/cgt.2015.32. Epub 2015 Jul 31. Review.


New Approaches for Modeling Radiopharmaceutical Pharmacokinetics Using Continuous Distributions of Rates.

Shuryak I, Dadachova E.

J Nucl Med. 2015 Oct;56(10):1622-8. doi: 10.2967/jnumed.115.160515. Epub 2015 Jul 23.


Preclinical testing of radiopharmaceuticals for novel applications in HIV, bacterial and fungal infectious diseases.

Shah M, Garg G, Dadachova E.

Q J Nucl Med Mol Imaging. 2015 Sep;59(3):317-26. Epub 2015 Jul 22. Review.


Fungal stress biology: a preface to the Fungal Stress Responses special edition.

Rangel DE, Alder-Rangel A, Dadachova E, Finlay RD, Kupiec M, Dijksterhuis J, Braga GU, Corrochano LM, Hallsworth JE.

Curr Genet. 2015 Aug;61(3):231-8. doi: 10.1007/s00294-015-0500-3. Epub 2015 Jun 27.


Radiolabeled Antibodies for Therapy of Infectious Diseases.

Dadachova E, Casadevall A.

Microbiol Spectr. 2014 Dec;2(6). doi: 10.1128/microbiolspec.AID-0023-2014. Review.


The International Symposium on Fungal Stress: ISFUS.

Rangel DE, Alder-Rangel A, Dadachova E, Finlay RD, Dijksterhuis J, Braga GU, Corrochano LM, Hallsworth JE.

Curr Genet. 2015 Aug;61(3):479-87. doi: 10.1007/s00294-015-0501-2. Epub 2015 Jun 23.


Naive and radiolabeled antibodies to E6 and E7 HPV-16 oncoproteins show pronounced antitumor activity in experimental cervical cancer.

Phaëton R, Gutierrez J, Jiang Z, Karabakhtsian RG, Albanese J, Sunkara J, Fisher DR, Goldberg GL, Dadachova E.

Immunotherapy. 2015;7(6):631-40. doi: 10.2217/imt.15.18. Epub 2015 Jun 22.


Non-invasive nuclear imaging for localization of viral reservoirs.

Dadachova E, Berman JW.

Nat Methods. 2015 May;12(5):399-400. doi: 10.1038/nmeth.3373. No abstract available.


Effects of radiation type and delivery mode on a radioresistant eukaryote Cryptococcus neoformans.

Shuryak I, Bryan RA, Broitman J, Marino SA, Morgenstern A, Apostolidis C, Dadachova E.

Nucl Med Biol. 2015 Jun;42(6):515-23. doi: 10.1016/j.nucmedbio.2015.02.006. Epub 2015 Mar 11.


Radiolabeled antibodies for therapy of infectious diseases.

Dadachova E, Casadevall A.

Microbiol Spectr. 2014 Nov;2(6):0023.


Effect of AIDS on women who have sex-determined health issues.

Sathekge M, Maes A, Van de Wiele C, Dadachova E.

Semin Nucl Med. 2014;44(6):489-98. doi: 10.1053/j.semnuclmed.2014.06.001. Review.


Treatment of experimental pancreatic cancer with 213-Bismuth-labeled chimeric antibody to single-strand DNA.

Bryan RA, Jiang Z, Jandl T, Strauss J, Koba W, Onyedika C, Morgenstern A, Bruchertseifer F, Epstein AL, Dadachova E.

Expert Rev Anticancer Ther. 2014 Oct;14(10):1243-9. doi: 10.1586/14737140.2014.952285. Epub 2014 Aug 26.


Role of nuclear medicine in neuroHIV: PET, SPECT, and beyond.

Sathekge M, McFarren A, Dadachova E.

Nucl Med Commun. 2014 Aug;35(8):792-6. doi: 10.1097/MNM.0000000000000139. Review.


The potential of radioimmunotherapy as a new hope for HIV patients.

Tsukrov D, Dadachova E.

Expert Rev Clin Immunol. 2014 May;10(5):553-5. doi: 10.1586/1744666X.2014.908706.


Branched amphiphilic peptide capsules: cellular uptake and retention of encapsulated solutes.

Sukthankar P, Avila LA, Whitaker SK, Iwamoto T, Morgenstern A, Apostolidis C, Liu K, Hanzlik RP, Dadachova E, Tomich JM.

Biochim Biophys Acta. 2014 Sep;1838(9):2296-305. doi: 10.1016/j.bbamem.2014.02.005. Epub 2014 Feb 22.


166Ho and 90Y labeled 6D2 monoclonal antibody for targeted radiotherapy of melanoma: comparison with 188Re radiolabel.

Thompson S, Ballard B, Jiang Z, Revskaya E, Sisay N, Miller WH, Cutler CS, Dadachova E, Francesconi LC.

Nucl Med Biol. 2014 Mar;41(3):276-81. doi: 10.1016/j.nucmedbio.2013.12.015. Epub 2013 Dec 30.

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