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Items: 7

1.

Ribosomal protein RPL26 is the principal target of UFMylation.

Walczak CP, Leto DE, Zhang L, Riepe C, Muller RY, DaRosa PA, Ingolia NT, Elias JE, Kopito RR.

Proc Natl Acad Sci U S A. 2019 Jan 22;116(4):1299-1308. doi: 10.1073/pnas.1816202116. Epub 2019 Jan 9.

2.

A Bifunctional Role for the UHRF1 UBL Domain in the Control of Hemi-methylated DNA-Dependent Histone Ubiquitylation.

DaRosa PA, Harrison JS, Zelter A, Davis TN, Brzovic P, Kuhlman B, Klevit RE.

Mol Cell. 2018 Nov 15;72(4):753-765.e6. doi: 10.1016/j.molcel.2018.09.029. Epub 2018 Nov 1.

3.

Structural basis for tankyrase-RNF146 interaction reveals noncanonical tankyrase-binding motifs.

DaRosa PA, Klevit RE, Xu W.

Protein Sci. 2018 Jun;27(6):1057-1067. doi: 10.1002/pro.3413. Epub 2018 Apr 25.

4.

Tuning BRCA1 and BARD1 activity to investigate RING ubiquitin ligase mechanisms.

Stewart MD, Duncan ED, Coronado E, DaRosa PA, Pruneda JN, Brzovic PS, Klevit RE.

Protein Sci. 2017 Mar;26(3):475-483. doi: 10.1002/pro.3091. Epub 2017 Jan 23.

5.

Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1.

Harrison JS, Cornett EM, Goldfarb D, DaRosa PA, Li ZM, Yan F, Dickson BM, Guo AH, Cantu DV, Kaustov L, Brown PJ, Arrowsmith CH, Erie DA, Major MB, Klevit RE, Krajewski K, Kuhlman B, Strahl BD, Rothbart SB.

Elife. 2016 Sep 6;5. pii: e17101. doi: 10.7554/eLife.17101.

6.

Structural insights into SAM domain-mediated tankyrase oligomerization.

DaRosa PA, Ovchinnikov S, Xu W, Klevit RE.

Protein Sci. 2016 Sep;25(9):1744-52. doi: 10.1002/pro.2968. Epub 2016 Jul 4.

7.

Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal.

DaRosa PA, Wang Z, Jiang X, Pruneda JN, Cong F, Klevit RE, Xu W.

Nature. 2015 Jan 8;517(7533):223-6. doi: 10.1038/nature13826. Epub 2014 Oct 19.

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