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Items: 1 to 50 of 205

1.
2.

Structure-function relationships of mitochondrial monoamine oxidase A and B: chimaeric enzymes and site-directed mutagenesis studies.

Cesura AM, Gottowik J, Lang G, Malherbe P, Da Prada M.

J Neural Transm Suppl. 1998;52:189-200.

PMID:
9564619
3.

Investigation on the structure of the active site of monoamine oxidase-B by affinity labeling with the selective inhibitor lazabemide and by site-directed mutagenesis.

Cesura AM, Gottowik J, Lahm HW, Lang G, Imhof R, Malherbe P, Röthlisberger U, Da Prada M.

Eur J Biochem. 1996 Mar 15;236(3):996-1002.

4.

Molecular neuroanatomy of human monoamine oxidases A and B revealed by quantitative enzyme radioautography and in situ hybridization histochemistry.

Saura J, Bleuel Z, Ulrich J, Mendelowitsch A, Chen K, Shih JC, Malherbe P, Da Prada M, Richards JG.

Neuroscience. 1996 Feb;70(3):755-74.

PMID:
9045087
5.

Response to Garrido et al.: "Side effects of the catechol-O-methyl-transferase inhibitor Ro 40-7592 in rabbits".

Da Prada M, Jorga KM.

Clin Neuropharmacol. 1996 Feb;19(1):98-9. No abstract available.

PMID:
8867524
6.

Assessment of catechol-O-methyltransferase activity and its inhibition in erythrocytes of animals and humans.

Zürcher G, Da Prada M, Dingemanse J.

Biomed Chromatogr. 1996 Jan-Feb;10(1):32-6.

PMID:
8821869
7.

Cellular expression of mRNAs encoding monoamine oxidases A and B in the rat central nervous system.

Luque JM, Kwan SW, Abell CW, Da Prada M, Richards JG.

J Comp Neurol. 1995 Dec 25;363(4):665-680.

PMID:
8847423
8.

Pharmacokinetic-pharmacodynamic interaction between the COMT inhibitor tolcapone and single-dose levodopa.

Dingemanse J, Jorga K, Zürcher G, Schmitt M, Sedek G, Da Prada M, Van Brummelen P.

Br J Clin Pharmacol. 1995 Sep;40(3):253-62.

9.

Structure/function relationships of mitochondrial monoamine oxidase A and B chimeric forms.

Gottowik J, Malherbe P, Lang G, Da Prada M, Cesura AM.

Eur J Biochem. 1995 Jun 15;230(3):934-42.

10.

Integrated pharmacokinetics and pharmacodynamics of the novel catechol-O-methyltransferase inhibitor tolcapone during first administration to humans.

Dingemanse J, Jorga KM, Schmitt M, Gieschke R, Fotteler B, Zürcher G, Da Prada M, van Brummelen P.

Clin Pharmacol Ther. 1995 May;57(5):508-17.

PMID:
7768073
11.

Effects of tolcapone, a novel catechol-O-methyltransferase inhibitor, on striatal metabolism of L-dopa and dopamine in rats.

Napolitano A, Zürcher G, Da Prada M.

Eur J Pharmacol. 1995 Feb 6;273(3):215-21.

PMID:
7737328
12.

The role of monoamine oxidase and catechol O-methyltransferase in dopaminergic neurotransmission.

Napolitano A, Cesura AM, Da Prada M.

J Neural Transm Suppl. 1995;45:35-45. Review.

PMID:
8748607
13.

Increased monoamine oxidase B activity in plaque-associated astrocytes of Alzheimer brains revealed by quantitative enzyme radioautography.

Saura J, Luque JM, Cesura AM, Da Prada M, Chan-Palay V, Huber G, Löffler J, Richards JG.

Neuroscience. 1994 Sep;62(1):15-30.

PMID:
7816197
14.

A novel acetylcholinesterase inhibitor, Ro 46-5934, which interacts with muscarinic M2 receptors.

Borroni E, Damsma G, Giovacchini C, Mutel V, Jakob-Rötne R, Da Prada M.

Biochem Soc Trans. 1994 Aug;22(3):755-8. No abstract available.

PMID:
7821679
16.

Radioautographic evidence that the GABAA receptor antagonist SR 95531 is a substrate inhibitor of MAO-A in the rat and human locus coeruleus.

Luque JM, Erat R, Kettler R, Cesura A, Da Prada M, Richards JG.

Eur J Neurosci. 1994 Jun 1;6(6):1038-49.

PMID:
7952273
17.

Molecular cloning and functional expression of human 3-hydroxyanthranilic-acid dioxygenase.

Malherbe P, Köhler C, Da Prada M, Lang G, Kiefer V, Schwarcz R, Lahm HW, Cesura AM.

J Biol Chem. 1994 May 13;269(19):13792-7.

18.

Estimation of rate constants for serotonin uptake and compartmentation in normal human platelets.

Launay G, Costa JL, Da Prada M, Launay JM.

Am J Physiol. 1994 Mar;266(3 Pt 2):R1061-75.

PMID:
8160855
19.

Species differences in changes of heart monoamine oxidase activities with age.

Strolin Benedetti M, Thomassin J, Tocchetti P, Dostert P, Kettler R, Da Prada M.

J Neural Transm Suppl. 1994;41:83-7.

PMID:
7931269
20.

Lazabemide (Ro 19-6327), a reversible and highly sensitive MAO-B inhibitor: preclinical and clinical findings.

Henriot S, Kuhn C, Kettler R, Da Prada M.

J Neural Transm Suppl. 1994;41:321-5.

PMID:
7931245
21.

Neurochemical and behavioral evidence that Ro 41-9067 is a selective presynaptic dopamine receptor agonist.

Nisoli E, Tonello C, Imhof R, Scherschlicht R, da Prada M, Carruba MO.

J Pharmacol Exp Ther. 1993 Jul;266(1):97-105.

PMID:
8101225
22.
23.

Characterisation of wild-type and mutant forms of human monoamine oxidase A and B expressed in a mammalian cell line.

Gottowik J, Cesura AM, Malherbe P, Lang G, Da Prada M.

FEBS Lett. 1993 Feb 8;317(1-2):152-6.

24.

Potent COMT inhibition by Ro 40-7592 in the periphery and in the brain. Preclinical and clinical findings.

Zürcher G, Dingemanse J, Da Prada M.

Adv Neurol. 1993;60:641-7. No abstract available.

PMID:
8420203
25.
26.

One-step purification of the serotonin transporter located at the human platelet plasma membrane.

Launay JM, Geoffroy C, Mutel V, Buckle M, Cesura A, Alouf JE, Da Prada M.

J Biol Chem. 1992 Jun 5;267(16):11344-51.

28.

Expression of functional membrane-bound and soluble catechol-O-methyltransferase in Escherichia coli and a mammalian cell line.

Malherbe P, Bertocci B, Caspers P, Zürcher G, Da Prada M.

J Neurochem. 1992 May;58(5):1782-9.

PMID:
1560233
29.

New insight into structural and stereochemical requirements for selective, high affinity ligands at the dopamine D2 receptor.

Imhof R, Godel T, Burkard WP, Keller HH, Da Prada M, Scherschlicht R.

Neurochem Int. 1992 Mar;20 Suppl:75S-80S. Review. No abstract available.

PMID:
1365460
30.

Catecholamine and serotonin depletion from rat spinal cord: effects on morphine and footshock induced analgesia.

Carruba MO, Nisoli E, Garosi V, Sacerdote P, Panerai AE, Da Prada M.

Pharmacol Res. 1992 Feb-Mar;25(2):187-94.

PMID:
1635896
31.

Biochemistry and pharmacology of moclobemide, a prototype RIMA.

Haefely W, Burkard WP, Cesura AM, Kettler R, Lorez HP, Martin JR, Richards JG, Scherschlicht R, Da Prada M.

Psychopharmacology (Berl). 1992;106 Suppl:S6-14. Review.

PMID:
1546143
32.

Interaction of moclobemide and tricyclic antidepressants with the tyramine pressor effect in rats.

Burkard W, d'Agostini F, Kettler R, Da Prada M.

Psychopharmacology (Berl). 1992;106 Suppl:S35-6.

PMID:
1546137
33.

Tyramine content of preserved and fermented foods or condiments of Far Eastern cuisine.

Da Prada M, Zürcher G.

Psychopharmacology (Berl). 1992;106 Suppl:S32-4.

PMID:
1546136
34.

Molecular neuroanatomy of monoamine oxidases in human brainstem.

Richards JG, Saura J, Ulrich J, Da Prada M.

Psychopharmacology (Berl). 1992;106 Suppl:S21-3.

PMID:
1546134
35.

Brain microdialysis in rats: a technique to reveal competition in vivo between endogenous dopamine and moclobemide, a RIMA antidepressant.

Colzi A, d'Agostini F, Cesura AM, Da Prada M.

Psychopharmacology (Berl). 1992;106 Suppl:S17-20.

PMID:
1546133
36.

Mode of action and characteristics of monoamine oxidase-A inhibition by moclobemide.

Cesura AM, Kettler R, Imhof R, Da Prada M.

Psychopharmacology (Berl). 1992;106 Suppl:S15-6.

PMID:
1546132
37.

Immunoaffinity purification and partial amino acid sequence analysis of catechol-O-methyltransferase from pig liver.

Bertocci B, Garotta G, Da Prada M, Lahm HW, Zürcher G, Virgallita G, Miggiano V.

Biochim Biophys Acta. 1991 Oct 25;1080(2):103-9.

PMID:
1932084
38.

New approaches to the treatment of age-related brain disorders.

Da Prada M.

Can J Neurol Sci. 1991 Aug;18(3 Suppl):384-6. Review.

PMID:
1933685
39.

Human catechol-O-methyltransferase: cloning and expression of the membrane-associated form.

Bertocci B, Miggiano V, Da Prada M, Dembic Z, Lahm HW, Malherbe P.

Proc Natl Acad Sci U S A. 1991 Feb 15;88(4):1416-20.

40.

Measurement of human cerebral monoamine oxidase type B (MAO-B) activity with positron emission tomography (PET): a dose ranging study with the reversible inhibitor Ro 19-6327.

Bench CJ, Price GW, Lammertsma AA, Cremer JC, Luthra SK, Turton D, Dolan RJ, Kettler R, Dingemanse J, Da Prada M, et al.

Eur J Clin Pharmacol. 1991;40(2):169-73.

PMID:
1906004
41.

Serotonin organelles of rabbit platelets contain synaptophysin.

Bähler M, Cesura AM, Fischer G, Kuhn H, Klein RL, Da Prada M.

Eur J Biochem. 1990 Dec 27;194(3):825-9.

42.

Simple automated high-performance liquid chromatographic column-switching technique for the measurement of dopa and 3-O-methyldopa in plasma.

Zürcher G, Da Prada M.

J Chromatogr. 1990 Sep 14;530(2):253-62. Erratum in: J Chromatogr 1990 Nov 16;532(2):466.

PMID:
2127780
43.
44.

Characterization of the binding of [3H]Ro 41-1049 to the active site of human monoamine oxidase-A.

Cesura AM, Bös M, Galva MD, Imhof R, Da Prada M.

Mol Pharmacol. 1990 Mar;37(3):358-66.

PMID:
2314388
45.

Characterization of [3H]Ro 16-6491 binding to digitonin solubilized monoamine oxidase-B and purification of the enzyme from human platelets by affinity chromatography.

Cesura AM, Imhof R, Muggli-Maniglio D, Picotti GB, Da Prada M.

Biochem Pharmacol. 1990 Jan 1;39(1):216-20. No abstract available.

PMID:
2297358
46.

Some basic aspects of reversible inhibitors of monoamine oxidase-A.

Da Prada M, Kettler R, Burkard WP, Lorez HP, Haefely W.

Acta Psychiatr Scand Suppl. 1990;360:7-12.

PMID:
2248079
47.

Species-specific biotransformation of moclobemide: a comparative study in rats and humans.

Schoerlin MP, Da Prada M.

Acta Psychiatr Scand Suppl. 1990;360:108-10.

PMID:
2248061
48.

Hypotensive action and weak potentiation of tyramine effect by moclobemide in rats.

Da Prada M, Burkard WP.

Acta Psychiatr Scand Suppl. 1990;360:106-7. Review.

PMID:
2248060
49.

Short-lasting and reversible inhibition of monoamine oxidase-A by moclobemide.

Da Prada M, Kettler R, Keller HH, Burkard WP.

Acta Psychiatr Scand Suppl. 1990;360:103-5. Review.

PMID:
2248059
50.

Comparison of monoamine oxidase-A inhibition by moclobemide in vitro and ex vivo in rats.

Kettler R, Da Prada M, Burkard WP.

Acta Psychiatr Scand Suppl. 1990;360:101-2. Review.

PMID:
2248058

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