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Items: 6

1.

Revertants, low temperature, and correctors reveal the mechanism of F508del-CFTR rescue by VX-809 and suggest multiple agents for full correction.

Farinha CM, King-Underwood J, Sousa M, Correia AR, Henriques BJ, Roxo-Rosa M, Da Paula AC, Williams J, Hirst S, Gomes CM, Amaral MD.

Chem Biol. 2013 Jul 25;20(7):943-55. doi: 10.1016/j.chembiol.2013.06.004.

2.

Phosphorylation-dependent 14-3-3 protein interactions regulate CFTR biogenesis.

Liang X, Da Paula AC, Bozóky Z, Zhang H, Bertrand CA, Peters KW, Forman-Kay JD, Frizzell RA.

Mol Biol Cell. 2012 Mar;23(6):996-1009. doi: 10.1091/mbc.E11-08-0662. Epub 2012 Jan 25.

3.

Folding and rescue of a cystic fibrosis transmembrane conductance regulator trafficking mutant identified using human-murine chimeric proteins.

Da Paula AC, Sousa M, Xu Z, Dawson ES, Boyd AC, Sheppard DN, Amaral MD.

J Biol Chem. 2010 Aug 27;285(35):27033-44. doi: 10.1074/jbc.M110.120352. Epub 2010 Jun 15.

4.

Chimeric constructs endow the human CFTR Cl- channel with the gating behavior of murine CFTR.

Scott-Ward TS, Cai Z, Dawson ES, Doherty A, Da Paula AC, Davidson H, Porteous DJ, Wainwright BJ, Amaral MD, Sheppard DN, Boyd AC.

Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16365-70. Epub 2007 Oct 3.

5.

CFTR gene transfer to human cystic fibrosis pancreatic duct cells using a Sendai virus vector.

Rakonczay Z Jr, Hegyi P, Hasegawa M, Inoue M, You J, Iida A, Ignáth I, Alton EW, Griesenbach U, Ovári G, Vág J, Da Paula AC, Crawford RM, Varga G, Amaral MD, Mehta A, Lonovics J, Argent BE, Gray MA.

J Cell Physiol. 2008 Feb;214(2):442-55.

PMID:
17654517
6.

Characterization of novel airway submucosal gland cell models for cystic fibrosis studies.

da Paula AC, Ramalho AS, Farinha CM, Cheung J, Maurisse R, Gruenert DC, Ousingsawat J, Kunzelmann K, Amaral MD.

Cell Physiol Biochem. 2005;15(6):251-62.

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