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Items: 10

1.

Optimization of Potent and Selective Ataxia Telangiectasia-Mutated Inhibitors Suitable for a Proof-of-Concept Study in Huntington's Disease Models.

Toledo-Sherman L, Breccia P, Cachope R, Bate JR, Angulo-Herrera I, Wishart G, Matthews KL, Martin SL, Cox HC, McAllister G, Penrose SD, Vater H, Esmieu W, Van de Poël A, Van de Bospoort R, Strijbosch A, Lamers M, Leonard P, Jarvis RE, Blackaby W, Barnes K, Eznarriaga M, Dowler S, Smith GD, Fischer DF, Lazari O, Yates D, Rose M, Jang SW, Muñoz-Sanjuan I, Dominguez C.

J Med Chem. 2019 Mar 28;62(6):2988-3008. doi: 10.1021/acs.jmedchem.8b01819. Epub 2019 Mar 19.

PMID:
30840447
2.

A monoclonal antibody TrkB receptor agonist as a potential therapeutic for Huntington's disease.

Todd D, Gowers I, Dowler SJ, Wall MD, McAllister G, Fischer DF, Dijkstra S, Fratantoni SA, van de Bospoort R, Veenman-Koepke J, Flynn G, Arjomand J, Dominguez C, Munoz-Sanjuan I, Wityak J, Bard JA.

PLoS One. 2014 Feb 4;9(2):e87923. doi: 10.1371/journal.pone.0087923. eCollection 2014.

3.

Reducing the complexity of the N-FINDR algorithm for hyperspectral image analysis.

Dowler SW, Takashima R, Andrews M.

IEEE Trans Image Process. 2013 Jul;22(7):2835-48. doi: 10.1109/TIP.2012.2219546. Epub 2012 Sep 28.

PMID:
23033430
4.

In vivo analysis of 3-phosphoinositide dynamics during Dictyostelium phagocytosis and chemotaxis.

Dormann D, Weijer G, Dowler S, Weijer CJ.

J Cell Sci. 2004 Dec 15;117(Pt 26):6497-509. Epub 2004 Nov 30.

5.

Protein lipid overlay assay.

Dowler S, Kular G, Alessi DR.

Sci STKE. 2002 Apr 23;2002(129):pl6.

PMID:
11972359
7.

Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities.

Dowler S, Currie RA, Campbell DG, Deak M, Kular G, Downes CP, Alessi DR.

Biochem J. 2000 Oct 1;351(Pt 1):19-31.

8.
9.

DAPP1: a dual adaptor for phosphotyrosine and 3-phosphoinositides.

Dowler S, Currie RA, Downes CP, Alessi DR.

Biochem J. 1999 Aug 15;342 ( Pt 1):7-12.

10.

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