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Items: 18

1.

Anticancer efficacy of the hypoxia-activated prodrug evofosfamide is enhanced in combination with proapoptotic receptor agonists against osteosarcoma.

Liapis V, Zysk A, DeNichilo M, Zinonos I, Hay S, Panagopoulos V, Shoubridge A, Difelice C, Ponomarev V, Ingman W, Atkins GJ, Findlay DM, Zannettino ACW, Evdokiou A.

Cancer Med. 2017 Sep;6(9):2164-2176. doi: 10.1002/cam4.1115. Epub 2017 Aug 10.

2.

Inflammatory peroxidases promote breast cancer progression in mice via regulation of the tumour microenvironment.

Panagopoulos V, Leach DA, Zinonos I, Ponomarev V, Licari G, Liapis V, Ingman WV, Anderson P, DeNichilo MO, Evdokiou A.

Int J Oncol. 2017 Apr;50(4):1191-1200. doi: 10.3892/ijo.2017.3883. Epub 2017 Feb 20.

PMID:
28260049
3.

Adoptive transfer of ex vivo expanded Vγ9Vδ2 T cells in combination with zoledronic acid inhibits cancer growth and limits osteolysis in a murine model of osteolytic breast cancer.

Zysk A, DeNichilo MO, Panagopoulos V, Zinonos I, Liapis V, Hay S, Ingman W, Ponomarev V, Atkins G, Findlay D, Zannettino A, Evdokiou A.

Cancer Lett. 2017 Feb 1;386:141-150. doi: 10.1016/j.canlet.2016.11.013. Epub 2016 Nov 16.

4.

Peroxidase enzymes inhibit osteoclast differentiation and bone resorption.

Panagopoulos V, Liapis V, Zinonos I, Hay S, Leach DA, Ingman W, DeNichilo MO, Atkins GJ, Findlay DM, Zannettino ACW, Evdokiou A.

Mol Cell Endocrinol. 2017 Jan 15;440:8-15. doi: 10.1016/j.mce.2016.11.007. Epub 2016 Nov 9.

PMID:
27836774
5.

Anticancer efficacy of the hypoxia-activated prodrug evofosfamide (TH-302) in osteolytic breast cancer murine models.

Liapis V, Zinonos I, Labrinidis A, Hay S, Ponomarev V, Panagopoulos V, Zysk A, DeNichilo M, Ingman W, Atkins GJ, Findlay DM, Zannettino AC, Evdokiou A.

Cancer Med. 2016 Mar;5(3):534-45. doi: 10.1002/cam4.599. Epub 2016 Jan 9.

6.

Peroxidase Enzymes Regulate Collagen Biosynthesis and Matrix Mineralization by Cultured Human Osteoblasts.

DeNichilo MO, Shoubridge AJ, Panagopoulos V, Liapis V, Zysk A, Zinonos I, Hay S, Atkins GJ, Findlay DM, Evdokiou A.

Calcif Tissue Int. 2016 Mar;98(3):294-305. doi: 10.1007/s00223-015-0090-6. Epub 2015 Dec 7.

PMID:
26643175
7.

Uncovering a new role for peroxidase enzymes as drivers of angiogenesis.

Panagopoulos V, Zinonos I, Leach DA, Hay SJ, Liapis V, Zysk A, Ingman WV, DeNichilo MO, Evdokiou A.

Int J Biochem Cell Biol. 2015 Nov;68:128-38. doi: 10.1016/j.biocel.2015.09.006. Epub 2015 Sep 18.

PMID:
26386352
8.

Peroxidase enzymes regulate collagen extracellular matrix biosynthesis.

DeNichilo MO, Panagopoulos V, Rayner TE, Borowicz RA, Greenwood JE, Evdokiou A.

Am J Pathol. 2015 May;185(5):1372-84. doi: 10.1016/j.ajpath.2015.01.013. Epub 2015 Mar 7.

PMID:
25759268
9.

Doxorubicin overcomes resistance to drozitumab by antagonizing Inhibitor of Apoptosis Proteins (IAPs).

Zinonos I, Labrinidis A, Liapis V, Hay S, Panagopoulos V, Denichilo M, Ponomarev V, Ingman W, Atkins GJ, Findlay DM, Zannettino AC, Evdokiou A.

Anticancer Res. 2014 Dec;34(12):7007-20.

PMID:
25503127
10.

Hypoxia-activated pro-drug TH-302 exhibits potent tumor suppressive activity and cooperates with chemotherapy against osteosarcoma.

Liapis V, Labrinidis A, Zinonos I, Hay S, Ponomarev V, Panagopoulos V, DeNichilo M, Ingman W, Atkins GJ, Findlay DM, Zannettino ACW, Evdokiou A.

Cancer Lett. 2015 Feb 1;357(1):160-169. doi: 10.1016/j.canlet.2014.11.020. Epub 2014 Nov 15.

11.

Pharmacologic inhibition of bone resorption prevents cancer-induced osteolysis but enhances soft tissue metastasis in a mouse model of osteolytic breast cancer.

Zinonos I, Luo KW, Labrinidis A, Liapis V, Hay S, Panagopoulos V, Denichilo M, Ko CH, Yue GG, Lau CB, Ingman W, Ponomarev V, Atkins GJ, Findlay DM, Zannettino AC, Evdokiou A.

Int J Oncol. 2014 Aug;45(2):532-40. doi: 10.3892/ijo.2014.2468. Epub 2014 May 27.

12.

Maternal milk, but not formula, regulates the immune response to beta-lactoglobulin in allergy-prone rat pups.

Tooley KL, El-Merhibi A, Cummins AG, Grose RH, Lymn KA, DeNichilo M, Penttila IA.

J Nutr. 2009 Nov;139(11):2145-51. doi: 10.3945/jn.109.108845. Epub 2009 Sep 16.

PMID:
19759244
13.

Supplementation with a whey protein hydrolysate enhances recovery of muscle force-generating capacity following eccentric exercise.

Buckley JD, Thomson RL, Coates AM, Howe PR, DeNichilo MO, Rowney MK.

J Sci Med Sport. 2010 Jan;13(1):178-81. doi: 10.1016/j.jsams.2008.06.007. Epub 2008 Sep 2.

PMID:
18768358
14.

Urinary CCN2 (CTGF) as a possible predictor of diabetic nephropathy: preliminary report.

Riser BL, Cortes P, DeNichilo M, Deshmukh PV, Chahal PS, Mohammed AK, Yee J, Kahkonen D.

Kidney Int. 2003 Aug;64(2):451-8.

15.

Connective tissue growth factor in tubulointerstitial injury of diabetic nephropathy.

Wang S, Denichilo M, Brubaker C, Hirschberg R.

Kidney Int. 2001 Jul;60(1):96-105.

16.

In vitro evidence for differential involvement of CTGF, TGFbeta, and PDGF-BB in mesangial response to injury.

Blom IE, van Dijk AJ, Wieten L, Duran K, Ito Y, Kleij L, deNichilo M, Rabelink TJ, Weening JJ, Aten J, Goldschmeding R.

Nephrol Dial Transplant. 2001 Jun;16(6):1139-48.

PMID:
11390712
17.

Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis.

Riser BL, Denichilo M, Cortes P, Baker C, Grondin JM, Yee J, Narins RG.

J Am Soc Nephrol. 2000 Jan;11(1):25-38.

18.

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