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Items: 34

1.

TETRABENAZINE FACILITATES EXOCYTOSIS BY ENHANCING CALCIUM-INDUCED CALCIUM RELEASE THROUGH RYANODINE RECEPTORS.

DE Pascual R, Alvarez-Ortego N, de Los Rios C, Jacob-Mazariego G, Garcia AG.

J Pharmacol Exp Ther. 2019 Jun 17. pii: jpet.119.256560. doi: 10.1124/jpet.119.256560. [Epub ahead of print]

2.

Otilonium and pinaverium trigger mitochondrial-mediated apoptosis in rat embryo cortical neurons in vitro.

García-Alvarado F, Govoni G, de Pascual R, Ruiz-Ruiz C, Muñoz-Montero A, Gandía L, de Diego AMG, García AG.

Neurotoxicology. 2019 Jan;70:99-111. doi: 10.1016/j.neuro.2018.11.003. Epub 2018 Nov 15.

PMID:
30448301
3.

Distinct patterns of exocytosis elicited by Ca2+, Sr2+ and Ba2+ in bovine chromaffin cells.

Baraibar AM, de Pascual R, Camacho M, Domínguez N, David Machado J, Gandía L, Borges R.

Pflugers Arch. 2018 Oct;470(10):1459-1471. doi: 10.1007/s00424-018-2166-4. Epub 2018 Jun 21.

PMID:
29926228
4.

Hydrogen sulphide facilitates exocytosis by regulating the handling of intracellular calcium by chromaffin cells.

de Pascual R, Baraibar AM, Méndez-López I, Pérez-Ciria M, Polo-Vaquero I, Gandía L, Ohia SE, García AG, de Diego AMG.

Pflugers Arch. 2018 Aug;470(8):1255-1270. doi: 10.1007/s00424-018-2147-7. Epub 2018 May 2.

PMID:
29721607
5.

Simultaneous monitoring of monoamines, amino acids, nucleotides and neuropeptides by liquid chromatography-tandem mass spectrometry and its application to neurosecretion in bovine chromaffin cells.

Wojnicz A, Avendaño-Ortiz J, de Pascual R, Ruiz-Pascual L, García AG, Ruiz-Nuño A.

J Mass Spectrom. 2016 Aug;51(8):651-664. doi: 10.1002/jms.3794.

PMID:
28239974
6.

Regulation by L channels of Ca(2+)-evoked secretory responses in ouabain-treated chromaffin cells.

De Pascual R, Colmena I, Ruiz-Pascual L, Baraibar AM, Egea J, Gandía L, García AG.

Pflugers Arch. 2016 Oct;468(10):1779-92. doi: 10.1007/s00424-016-1866-x. Epub 2016 Aug 24.

PMID:
27558258
7.

Novel synthetic sulfoglycolipid IG20 facilitates exocytosis in chromaffin cells through the regulation of sodium channels.

Crespo-Castrillo A, Punzón E, de Pascual R, Maroto M, Padín JF, García-Álvarez I, Nanclares C, Ruiz-Pascual L, Gandía L, Fernández-Mayoralas A, García AG.

J Neurochem. 2015 Dec;135(5):880-96. doi: 10.1111/jnc.13357. Epub 2015 Oct 14.

8.

Depressed excitability and ion currents linked to slow exocytotic fusion pore in chromaffin cells of the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.

Calvo-Gallardo E, de Pascual R, Fernández-Morales JC, Arranz-Tagarro JA, Maroto M, Nanclares C, Gandía L, de Diego AM, Padín JF, García AG.

Am J Physiol Cell Physiol. 2015 Jan 1;308(1):C1-19. doi: 10.1152/ajpcell.00272.2014. Epub 2014 Nov 5.

9.

Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.

Hermann PC, Sancho P, Cañamero M, Martinelli P, Madriles F, Michl P, Gress T, de Pascual R, Gandia L, Guerra C, Barbacid M, Wagner M, Vieira CR, Aicher A, Real FX, Sainz B Jr, Heeschen C.

Gastroenterology. 2014 Nov;147(5):1119-33.e4. doi: 10.1053/j.gastro.2014.08.002. Epub 2014 Aug 12.

PMID:
25127677
10.

Selective activation of α7 nicotinic acetylcholine receptor (nAChRα7) inhibits muscular degeneration in mdx dystrophic mice.

Leite PE, Gandía L, de Pascual R, Nanclares C, Colmena I, Santos WC, Lagrota-Candido J, Quirico-Santos T.

Brain Res. 2014 Jul 21;1573:27-36. doi: 10.1016/j.brainres.2014.05.004. Epub 2014 May 14.

11.

Plasmalemmal sodium-calcium exchanger shapes the calcium and exocytotic signals of chromaffin cells at physiological temperature.

Padín JF, Fernández-Morales JC, Olivares R, Vestring S, Arranz-Tagarro JA, Calvo-Gallardo E, de Pascual R, Gandía L, García AG.

Am J Physiol Cell Physiol. 2013 Jul 15;305(2):C160-72. doi: 10.1152/ajpcell.00016.2013. Epub 2013 Apr 17.

12.

Lower density of L-type and higher density of P/Q-type of calcium channels in chromaffin cells of hypertensive, compared with normotensive rats.

de Pascual R, Miranda-Ferreira R, Galvão KM, Lameu C, Ulrich H, Smaili SS, Jurkiewicz A, García AG, Gandía L.

Eur J Pharmacol. 2013 Apr 15;706(1-3):25-35. doi: 10.1016/j.ejphar.2013.02.046. Epub 2013 Mar 13.

PMID:
23499685
13.

Regulation by L-type calcium channels of endocytosis: an overview.

Rosa JM, Nanclares C, Orozco A, Colmena I, de Pascual R, García AG, Gandía L.

J Mol Neurosci. 2012 Oct;48(2):360-7. Epub 2012 May 12. Review.

PMID:
22581437
14.

Paradoxical facilitation of exocytosis by inhibition of L-type calcium channels of bovine chromaffin cells.

Rosa JM, Conde M, Nanclares C, Orozco A, Colmena I, de Pascual R, García AG, Gandía L.

Biochem Biophys Res Commun. 2011 Jul 1;410(2):307-11. doi: 10.1016/j.bbrc.2011.05.138. Epub 2011 May 31.

PMID:
21663733
15.

Greater cytosolic and mitochondrial calcium transients in adrenal medullary slices of hypertensive, compared with normotensive rats.

Miranda-Ferreira R, de Pascual R, Smaili SS, Caricati-Neto A, Gandía L, García AG, Jurkiewicz A.

Eur J Pharmacol. 2010 Jun 25;636(1-3):126-36. doi: 10.1016/j.ejphar.2010.03.044. Epub 2010 Mar 31.

PMID:
20361955
16.

Use of transgenic (knockout) mice reveals a site distinct from the alpha2A-adrenoceptors for agmatine in the vas deferens.

Santos WC, Garcez-do-Carmo L, da Silva EC, de Pascual R, Jurkiewicz NH, Jurkiewicz A, Gandía L.

Pharmacol Rep. 2009 Mar-Apr;61(2):325-9.

17.

Role of the endoplasmic reticulum and mitochondria on quantal catecholamine release from chromaffin cells of control and hypertensive rats.

Miranda-Ferreira R, de Pascual R, Caricati-Neto A, Gandía L, Jurkiewicz A, García AG.

J Pharmacol Exp Ther. 2009 Apr;329(1):231-40. doi: 10.1124/jpet.108.147413. Epub 2009 Jan 8.

PMID:
19131584
18.

Single-vesicle catecholamine release has greater quantal content and faster kinetics in chromaffin cells from hypertensive, as compared with normotensive, rats.

Miranda-Ferreira R, de Pascual R, de Diego AM, Caricati-Neto A, Gandía L, Jurkiewicz A, García AG.

J Pharmacol Exp Ther. 2008 Feb;324(2):685-93. Epub 2007 Oct 25.

PMID:
17962518
19.
20.

[Anticholinesterases in the treatment of Alzheimer's disease].

Gandía L, Alvarez RM, Hernández-Guijo JM, González-Rubio JM, de Pascual R, Rojo J, Tapia L.

Rev Neurol. 2006 Apr 16-30;42(8):471-7. Review. Spanish.

21.

Preclinical profile of PF9404C, a nitric oxide donor with beta receptor blocking properties.

Villarroya M, López MG, de Pascual R, García AG.

Cardiovasc Drug Rev. 2005 Summer;23(2):149-60. Review.

PMID:
16007231
22.

Altered regulation of calcium channels and exocytosis in single human pheochromocytoma cells.

Hernández-Guijo JM, Gandía L, Cuchillo-Ibáñez I, Albillos A, Novalbos J, Gilsanz F, Larrañaga E, de Pascual R, Abad F, García AG.

Pflugers Arch. 2000 Jun;440(2):253-63.

PMID:
10898526
23.

PF9404C, a new slow NO donor with beta receptor blocking properties.

Villarroya M, Herrero CJ, Ruíz-Nuño A, de Pascual R, del Valle M, Michelena P, Grau M, Carrasco E, López MG, García AG.

Br J Pharmacol. 1999 Dec;128(8):1713-22.

24.

Voltage inactivation of Ca2+ entry and secretion associated with N- and P/Q-type but not L-type Ca2+ channels of bovine chromaffin cells.

Villarroya M, Olivares R, Ruíz A, Cano-Abad MF, de Pascual R, Lomax RB, López MG, Mayorgas I, Gandía L, García AG.

J Physiol. 1999 Apr 15;516 ( Pt 2):421-32.

25.

Human adrenal chromaffin cell calcium channels: drastic current facilitation in cell clusters, but not in isolated cells.

Gandía L, Mayorgas I, Michelena P, Cuchillo I, de Pascual R, Abad F, Novalbos JM, Larrañaga E, García AG.

Pflugers Arch. 1998 Oct;436(5):696-704.

PMID:
9716702
26.

Separation of calcium channel current components in mouse chromaffin cells superfused with low- and high-barium solutions.

Hernández-Guijo JM, de Pascual R, García AG, Gandía L.

Pflugers Arch. 1998 Jun;436(1):75-82.

PMID:
9560449
27.

Differential effects of the neuroprotectant lubeluzole on bovine and mouse chromaffin cell calcium channel subtypes.

Hernández-Guijo JM, Gandía L, de Pascual R, García AG.

Br J Pharmacol. 1997 Sep;122(2):275-85.

28.

Effects of omega-toxins on noradrenergic neurotransmission in beating guinea pig atria.

Vega T, De Pascual R, Bulbena O, García AG.

Eur J Pharmacol. 1995 Apr 4;276(3):231-8.

PMID:
7601208
29.

Endothelium-independent relaxation by 17-alpha-estradiol of pig coronary arteries.

Salas E, López MG, Villarroya M, Sánchez-García P, De Pascual R, Dixon WR, García AG.

Eur J Pharmacol. 1994 Jun 2;258(1-2):47-55.

PMID:
7925599
30.

PCA 50941, a novel Ca2+ channel agonist.

Priego J, González-Morales MA, Cillero FJ, Villarroya M, Sunkel C, de Casa-Juana MF, López MG, Artalejo CR, de Pascual R, García AG.

Eur J Pharmacol. 1993 Oct 12;243(1):25-34.

PMID:
7504630
31.

Membrane-mediated effects of the steroid 17-alpha-estradiol on adrenal catecholamine release.

López MG, Abad F, Sancho C, de Pascual R, Borges R, Maroto R, Dixon W, Garcia AG.

J Pharmacol Exp Ther. 1991 Oct;259(1):279-85.

PMID:
1920120
32.

Different sensitivities to dihydropyridines of catecholamine release from cat and ox adrenals.

Gandía L, Michelena P, de Pascual R, López MG, García AG.

Neuroreport. 1990 Oct;1(2):119-22.

PMID:
1717038
33.

Voltage-dependent inactivation of catecholamine secretion evoked by brief calcium pulses in the cat adrenal medulla.

Garrido B, López MG, Moro MA, de Pascual R, García AG.

J Physiol. 1990 Sep;428:615-37.

34.

Voltage-dependence of nitrendipine provides direct evidence for dihydropyridine receptor coupling to calcium channels in intact cat adrenals.

Artalejo CR, López MG, Moro MA, Castillo CF, de Pascual R, García AG.

Biochem Biophys Res Commun. 1988 Jun 30;153(3):912-8.

PMID:
2455516

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