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Items: 38

1.

Soluble Markers of Antibody Secreting Cell Function as Predictors of Infection Risk in Rheumatoid Arthritis.

Gutierrez MJ, Desiderio SV, Wang NY, Darrah E, Cappelli L, Nino G, Jones M, Bingham CO 3rd.

J Immunol Res. 2019 Apr 28;2019:3658215. doi: 10.1155/2019/3658215. eCollection 2019.

2.

Conserved Gammaherpesvirus Protein Kinase Selectively Promotes Irrelevant B Cell Responses.

Darrah EJ, Jondle CN, Johnson KE, Xin G, Lange PT, Cui W, Olteanu H, Tarakanova VL.

J Virol. 2019 Apr 3;93(8). pii: e01760-18. doi: 10.1128/JVI.01760-18. Print 2019 Apr 15.

PMID:
30728267
3.

Clinical Utility of Antipeptidyl Arginine Deiminase Type 4 Antibodies.

Darrah E, Martinez-Prat L, Mahler M.

J Rheumatol. 2019 Mar;46(3):329-330. doi: 10.3899/jrheum.180905. Epub 2019 Jan 15. No abstract available.

PMID:
30647163
4.

LXR Alpha Restricts Gammaherpesvirus Reactivation from Latently Infected Peritoneal Cells.

Lange PT, Jondle CN, Darrah EJ, Johnson KE, Tarakanova VL.

J Virol. 2019 Mar 5;93(6). pii: e02071-18. doi: 10.1128/JVI.02071-18. Print 2019 Mar 15.

PMID:
30602604
5.

Association of Baseline Peptidylarginine Deiminase 4 Autoantibodies With Favorable Response to Treatment Escalation in Rheumatoid Arthritis.

Darrah E, Yu F, Cappelli LC, Rosen A, O'Dell JR, Mikuls TR.

Arthritis Rheumatol. 2019 May;71(5):696-702. doi: 10.1002/art.40791. Epub 2019 Apr 10.

PMID:
30507066
6.

Autoantibodies to Peptidylarginine Deiminase 2 Are Associated With Less Severe Disease in Rheumatoid Arthritis.

Darrah E, Giles JT, Davis RL, Naik P, Wang H, Konig MF, Cappelli LC, Bingham CO 3rd, Danoff SK, Andrade F.

Front Immunol. 2018 Nov 20;9:2696. doi: 10.3389/fimmu.2018.02696. eCollection 2018.

7.

Smoking is not linked to the development of anti-peptidylarginine deiminase 4 autoantibodies in rheumatoid arthritis.

Cappelli LC, Konig MF, Gelber AC, Bingham CO 3rd, Darrah E.

Arthritis Res Ther. 2018 Mar 23;20(1):59. doi: 10.1186/s13075-018-1533-z.

8.

Affinity maturation shapes the function of agonistic antibodies to peptidylarginine deiminase type 4 in rheumatoid arthritis.

Shi J, Darrah E, Sims GP, Mustelin T, Sampson K, Konig MF, Bingham CO 3rd, Rosen A, Andrade F.

Ann Rheum Dis. 2018 Jan;77(1):141-148. doi: 10.1136/annrheumdis-2017-211489. Epub 2017 Oct 25.

9.

Spontaneous Secretion of the Citrullination Enzyme PAD2 and Cell Surface Exposure of PAD4 by Neutrophils.

Zhou Y, Chen B, Mittereder N, Chaerkady R, Strain M, An LL, Rahman S, Ma W, Low CP, Chan D, Neal F, Bingham CO 3rd, Sampson K, Darrah E, Siegel RM, Hasni S, Andrade F, Vousden KA, Mustelin T, Sims GP.

Front Immunol. 2017 Sep 25;8:1200. doi: 10.3389/fimmu.2017.01200. eCollection 2017.

10.

Rheumatoid arthritis and citrullination.

Darrah E, Andrade F.

Curr Opin Rheumatol. 2018 Jan;30(1):72-78. doi: 10.1097/BOR.0000000000000452. Review.

11.

ATM supports gammaherpesvirus replication by attenuating type I interferon pathway.

Darrah EJ, Stoltz KP, Ledwith M, Tarakanova VL.

Virology. 2017 Oct;510:137-146. doi: 10.1016/j.virol.2017.07.014. Epub 2017 Jul 18.

12.

B Cell-Specific Expression of Ataxia-Telangiectasia Mutated Protein Kinase Promotes Chronic Gammaherpesvirus Infection.

Darrah EJ, Kulinski JM, Mboko WP, Xin G, Malherbe LP, Gauld SB, Cui W, Tarakanova VL.

J Virol. 2017 Sep 12;91(19). pii: e01103-17. doi: 10.1128/JVI.01103-17. Print 2017 Oct 1.

13.

Distorted Immunodominance by Linker Sequences or other Epitopes from a Second Protein Antigen During Antigen-Processing.

Kim A, Boronina TN, Cole RN, Darrah E, Sadegh-Nasseri S.

Sci Rep. 2017 Apr 19;7:46418. doi: 10.1038/srep46418.

14.

Association of anti-peptidyl arginine deiminase antibodies with radiographic severity of rheumatoid arthritis in African Americans.

Navarro-Millán I, Darrah E, Westfall AO, Mikuls TR, Reynolds RJ, Danila MI, Curtis JR; CLEAR Investigators, Rosen A, Bridges SL Jr.

Arthritis Res Ther. 2016 Oct 22;18(1):241.

15.

Proteolysis by Granzyme B Enhances Presentation of Autoantigenic Peptidylarginine Deiminase 4 Epitopes in Rheumatoid Arthritis.

Darrah E, Kim A, Zhang X, Boronina T, Cole RN, Fava A, Giles JT, Bingham III CO, Chalmers MJ, Griffin PR, Sadegh-Nasseri S, Rosen A.

J Proteome Res. 2017 Jan 6;16(1):355-365. doi: 10.1021/acs.jproteome.6b00617. Epub 2016 Oct 20.

16.

Anti-peptidyl-arginine deaminase 3 (PAD3) antibodies as a promising marker to measure joint damage in patients with rheumatoid arthritis.

Seaman A, Darrah E, Infantino M, Meacci F, Manfredi M, Benucci M, Mahler M.

Autoimmun Rev. 2016 Jul;15(7):776-80. doi: 10.1016/j.autrev.2016.03.016. Epub 2016 Mar 18. Review.

PMID:
26997641
17.

Gammaherpesvirus targets peritoneal B-1 B cells for long-term latency.

Rekow MM, Darrah EJ, Mboko WP, Lange PT, Tarakanova VL.

Virology. 2016 May;492:140-4. doi: 10.1016/j.virol.2016.02.022. Epub 2016 Mar 21.

18.

Type I Interferon Counteracts Antiviral Effects of Statins in the Context of Gammaherpesvirus Infection.

Lange PT, Darrah EJ, Vonderhaar EP, Mboko WP, Rekow MM, Patel SB, Sidjanin DJ, Tarakanova VL.

J Virol. 2016 Jan 6;90(7):3342-54. doi: 10.1128/JVI.02277-15.

19.

Tumor Suppressor Interferon-Regulatory Factor 1 Counteracts the Germinal Center Reaction Driven by a Cancer-Associated Gammaherpesvirus.

Mboko WP, Olteanu H, Ray A, Xin G, Darrah EJ, Kumar SN, Kulinski JM, Cui W, Dittel BN, Gauld SB, Tarakanova VL.

J Virol. 2015 Dec 30;90(6):2818-29. doi: 10.1128/JVI.02774-15.

20.

ATM facilitates mouse gammaherpesvirus reactivation from myeloid cells during chronic infection.

Kulinski JM, Darrah EJ, Broniowska KA, Mboko WP, Mounce BC, Malherbe LP, Corbett JA, Gauld SB, Tarakanova VL.

Virology. 2015 Sep;483:264-74. doi: 10.1016/j.virol.2015.04.026. Epub 2015 May 21.

21.

Editorial: citrullination, and carbamylation, and malondialdehyde-acetaldehyde! Oh my! Entering the forest of autoantigen modifications in rheumatoid arthritis.

Darrah E, Andrade F.

Arthritis Rheumatol. 2015 Mar;67(3):604-8. doi: 10.1002/art.38970. No abstract available.

22.

Association of cross-reactive antibodies targeting peptidyl-arginine deiminase 3 and 4 with rheumatoid arthritis-associated interstitial lung disease.

Giles JT, Darrah E, Danoff S, Johnson C, Andrade F, Rosen A, Bathon JM.

PLoS One. 2014 Jun 5;9(6):e98794. doi: 10.1371/journal.pone.0098794. eCollection 2014.

24.

Interferon regulatory factor 1 restricts gammaherpesvirus replication in primary immune cells.

Mboko WP, Mounce BC, Emmer J, Darrah E, Patel SB, Tarakanova VL.

J Virol. 2014 Jun;88(12):6993-7004. doi: 10.1128/JVI.00638-14. Epub 2014 Apr 9.

25.

Association of the autoimmune disease scleroderma with an immunologic response to cancer.

Joseph CG, Darrah E, Shah AA, Skora AD, Casciola-Rosen LA, Wigley FM, Boin F, Fava A, Thoburn C, Kinde I, Jiao Y, Papadopoulos N, Kinzler KW, Vogelstein B, Rosen A.

Science. 2014 Jan 10;343(6167):152-7. doi: 10.1126/science.1246886. Epub 2013 Dec 5.

26.

UNC79 and UNC80, putative auxiliary subunits of the NARROW ABDOMEN ion channel, are indispensable for robust circadian locomotor rhythms in Drosophila.

Lear BC, Darrah EJ, Aldrich BT, Gebre S, Scott RL, Nash HA, Allada R.

PLoS One. 2013 Nov 5;8(11):e78147. doi: 10.1371/journal.pone.0078147. eCollection 2013.

27.

Immune-mediated pore-forming pathways induce cellular hypercitrullination and generate citrullinated autoantigens in rheumatoid arthritis.

Romero V, Fert-Bober J, Nigrovic PA, Darrah E, Haque UJ, Lee DM, van Eyk J, Rosen A, Andrade F.

Sci Transl Med. 2013 Oct 30;5(209):209ra150. doi: 10.1126/scitranslmed.3006869.

28.

Prevalence of anti-peptidylarginine deiminase type 4 antibodies in rheumatoid arthritis and unaffected first-degree relatives in indigenous North American Populations.

Ferucci ED, Darrah E, Smolik I, Choromanski TL, Robinson DB, Newkirk MM, Fritzler MJ, Rosen A, El-Gabalawy HS.

J Rheumatol. 2013 Sep;40(9):1523-8. doi: 10.3899/jrheum.130293. Epub 2013 Aug 1.

29.

Erosive rheumatoid arthritis is associated with antibodies that activate PAD4 by increasing calcium sensitivity.

Darrah E, Giles JT, Ols ML, Bull HG, Andrade F, Rosen A.

Sci Transl Med. 2013 May 22;5(186):186ra65. doi: 10.1126/scitranslmed.3005370.

30.

NETs: the missing link between cell death and systemic autoimmune diseases?

Darrah E, Andrade F.

Front Immunol. 2013 Jan 17;3:428. doi: 10.3389/fimmu.2012.00428. eCollection 2012.

31.

Peptidylarginine deiminase 2, 3 and 4 have distinct specificities against cellular substrates: novel insights into autoantigen selection in rheumatoid arthritis.

Darrah E, Rosen A, Giles JT, Andrade F.

Ann Rheum Dis. 2012 Jan;71(1):92-8. doi: 10.1136/ard.2011.151712. Epub 2011 Aug 21.

32.

Autoimmunity to peptidyl arginine deiminase type 4 precedes clinical onset of rheumatoid arthritis.

Kolfenbach JR, Deane KD, Derber LA, O'Donnell CI, Gilliland WR, Edison JD, Rosen A, Darrah E, Norris JM, Holers VM.

Arthritis Rheum. 2010 Sep;62(9):2633-9. doi: 10.1002/art.27570.

33.

Autocitrullination of human peptidyl arginine deiminase type 4 regulates protein citrullination during cell activation.

Andrade F, Darrah E, Gucek M, Cole RN, Rosen A, Zhu X.

Arthritis Rheum. 2010 Jun;62(6):1630-40. doi: 10.1002/art.27439.

34.

Granzyme B cleavage of autoantigens in autoimmunity.

Darrah E, Rosen A.

Cell Death Differ. 2010 Apr;17(4):624-32. doi: 10.1038/cdd.2009.197. Epub 2010 Jan 15. Review.

35.

Association of autoimmunity to peptidyl arginine deiminase type 4 with genotype and disease severity in rheumatoid arthritis.

Harris ML, Darrah E, Lam GK, Bartlett SJ, Giles JT, Grant AV, Gao P, Scott WW Jr, El-Gabalawy H, Casciola-Rosen L, Barnes KC, Bathon JM, Rosen A.

Arthritis Rheum. 2008 Jul;58(7):1958-67. doi: 10.1002/art.23596.

36.

The voltage-gated potassium channel Kv1.3 is highly expressed on inflammatory infiltrates in multiple sclerosis brain.

Rus H, Pardo CA, Hu L, Darrah E, Cudrici C, Niculescu T, Niculescu F, Mullen KM, Allie R, Guo L, Wulff H, Beeton C, Judge SI, Kerr DA, Knaus HG, Chandy KG, Calabresi PA.

Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):11094-9. Epub 2005 Jul 25.

37.

An enlarging abdominal mass.

Torkington J, Darrah ER, O'Riordan B.

Postgrad Med J. 1998 Oct;74(876):623-4. No abstract available.

38.

Radiology of the duodenum.

Darrah ER, Nolan DJ.

Hosp Med. 1999 Jan;60(1):10-8. Review.

PMID:
10197092

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