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Items: 14

1.

Brain-targeted stem cell gene therapy corrects mucopolysaccharidosis type II via multiple mechanisms.

Gleitz HF, Liao AY, Cook JR, Rowlston SF, Forte GM, D'Souza Z, O'Leary C, Holley RJ, Bigger BW.

EMBO Mol Med. 2018 Jun 8. pii: e8730. doi: 10.15252/emmm.201708730. [Epub ahead of print]

2.

A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency.

Tordo J, O'Leary C, Antunes ASLM, Palomar N, Aldrin-Kirk P, Basche M, Bennett A, D'Souza Z, Gleitz H, Godwin A, Holley RJ, Parker H, Liao AY, Rouse P, Youshani AS, Dridi L, Martins C, Levade T, Stacey KB, Davis DM, Dyer A, Clément N, Björklund T, Ali RR, Agbandje-McKenna M, Rahim AA, Pshezhetsky A, Waddington SN, Linden RM, Bigger BW, Henckaerts E.

Brain. 2018 May 16. doi: 10.1093/brain/awy126. [Epub ahead of print]

PMID:
29788236
3.

Macrophage enzyme and reduced inflammation drive brain correction of mucopolysaccharidosis IIIB by stem cell gene therapy.

Holley RJ, Ellison SM, Fil D, O'Leary C, McDermott J, Senthivel N, Langford-Smith AWW, Wilkinson FL, D'Souza Z, Parker H, Liao A, Rowlston S, Gleitz HFE, Kan SH, Dickson PI, Bigger BW.

Brain. 2018 Jan 1;141(1):99-116. doi: 10.1093/brain/awx311.

PMID:
29186350
4.

Hemidesmosomal linker proteins regulate cell motility, invasion and tumorigenicity in oral squamous cell carcinoma derived cells.

Chaudhari PR, Charles SE, D'Souza ZC, Vaidya MM.

Exp Cell Res. 2017 Nov 15;360(2):125-137. doi: 10.1016/j.yexcr.2017.08.034. Epub 2017 Sep 1.

PMID:
28867478
5.

Vimentin regulates differentiation switch via modulation of keratin 14 levels and their expression together correlates with poor prognosis in oral cancer patients.

Dmello C, Sawant S, Alam H, Gangadaran P, Mogre S, Tiwari R, D'Souza Z, Narkar M, Thorat R, Patil K, Chaukar D, Kane S, Vaidya M.

PLoS One. 2017 Feb 22;12(2):e0172559. doi: 10.1371/journal.pone.0172559. eCollection 2017.

6.

De novo DNA methylation drives 5hmC accumulation in mouse zygotes.

Amouroux R, Nashun B, Shirane K, Nakagawa S, Hill PW, D'Souza Z, Nakayama M, Matsuda M, Turp A, Ndjetehe E, Encheva V, Kudo NR, Koseki H, Sasaki H, Hajkova P.

Nat Cell Biol. 2016 Feb;18(2):225-233. doi: 10.1038/ncb3296. Epub 2016 Jan 11.

7.

Kcnn4 is a regulator of macrophage multinucleation in bone homeostasis and inflammatory disease.

Kang H, Kerloc'h A, Rotival M, Xu X, Zhang Q, D'Souza Z, Kim M, Scholz JC, Ko JH, Srivastava PK, Genzen JR, Cui W, Aitman TJ, Game L, Melvin JE, Hanidu A, Dimock J, Zheng J, Souza D, Behera AK, Nabozny G, Cook HT, Bassett JH, Williams GR, Li J, Vignery A, Petretto E, Behmoaras J.

Cell Rep. 2014 Aug 21;8(4):1210-24. doi: 10.1016/j.celrep.2014.07.032. Epub 2014 Aug 14.

8.

Experimental crescentic glomerulonephritis: a new bicongenic rat model.

D'Souza Z, McAdoo SP, Smith J, Pusey CD, Cook HT, Behmoaras J, Aitman TJ.

Dis Model Mech. 2013 Nov;6(6):1477-86. doi: 10.1242/dmm.012328. Epub 2013 Aug 15.

9.

Combined ChIP-Seq and transcriptome analysis identifies AP-1/JunD as a primary regulator of oxidative stress and IL-1β synthesis in macrophages.

Hull RP, Srivastava PK, D'Souza Z, Atanur SS, Mechta-Grigoriou F, Game L, Petretto E, Cook HT, Aitman TJ, Behmoaras J.

BMC Genomics. 2013 Feb 11;14:92. doi: 10.1186/1471-2164-14-92.

10.

Role of novel rat-specific Fc receptor in macrophage activation associated with crescentic glomerulonephritis.

Page TH, D'Souza Z, Nakanishi S, Serikawa T, Pusey CD, Aitman TJ, Cook HT, Behmoaras J.

J Biol Chem. 2012 Feb 17;287(8):5710-9. doi: 10.1074/jbc.M111.260695. Epub 2011 Dec 19.

11.

AP-1 transcription factor JunD confers protection from accelerated nephrotoxic nephritis and control podocyte-specific Vegfa expression.

Cook HT, Tarzi R, D'Souza Z, Laurent G, Lin WC, Aitman TJ, Mechta-Grigoriou F, Behmoaras J.

Am J Pathol. 2011 Jul;179(1):134-40. doi: 10.1016/j.ajpath.2011.03.006. Epub 2011 May 3.

12.

Characterization of the macrophage transcriptome in glomerulonephritis-susceptible and -resistant rat strains.

Maratou K, Behmoaras J, Fewings C, Srivastava P, D'Souza Z, Smith J, Game L, Cook T, Aitman T.

Genes Immun. 2011 Mar;12(2):78-89. doi: 10.1038/gene.2010.61. Epub 2010 Dec 23.

13.

Genetic loci modulate macrophage activity and glomerular damage in experimental glomerulonephritis.

Behmoaras J, Smith J, D'Souza Z, Bhangal G, Chawanasuntoropoj R, Tam FW, Pusey CD, Aitman TJ, Cook HT.

J Am Soc Nephrol. 2010 Jul;21(7):1136-44. doi: 10.1681/ASN.2009090968. Epub 2010 May 20.

14.

Urinary tract infection during pregnancy--dipstick urinalysis vs. culture and sensitivity.

D'Souza Z, D'Souza D.

J Obstet Gynaecol. 2004 Jan;24(1):22-4.

PMID:
14675975

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