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Items: 42

1.

A manganese oxide nanozyme prevents the oxidative damage of biomolecules without affecting the endogenous antioxidant system.

Singh N, Savanur MA, Srivastava S, D'Silva P, Mugesh G.

Nanoscale. 2019 Feb 28;11(9):3855-3863. doi: 10.1039/c8nr09397k.

PMID:
30758009
2.

A Redox Modulatory Mn3 O4 Nanozyme with Multi-Enzyme Activity Provides Efficient Cytoprotection to Human Cells in a Parkinson's Disease Model.

Singh N, Savanur MA, Srivastava S, D'Silva P, Mugesh G.

Angew Chem Int Ed Engl. 2017 Nov 6;56(45):14267-14271. doi: 10.1002/anie.201708573. Epub 2017 Oct 4.

PMID:
28922532
3.

Regulation of mitochondrial protein import by the nucleotide exchange factors GrpEL1 and GrpEL2 in human cells.

Srivastava S, Savanur MA, Sinha D, Birje A, R V, Saha PP, D'Silva P.

J Biol Chem. 2017 Nov 3;292(44):18075-18090. doi: 10.1074/jbc.M117.788463. Epub 2017 Aug 28.

4.

Iron-Sulfur Protein Assembly in Human Cells.

Saha PP, Vishwanathan V, Bankapalli K, D'Silva P.

Rev Physiol Biochem Pharmacol. 2018;174:25-65. doi: 10.1007/112_2017_5. Review.

PMID:
28828516
5.

Methylglyoxal detoxification by a DJ-1 family protein provides dual abiotic and biotic stress tolerance in transgenic plants.

Melvin P, Bankapalli K, D'Silva P, Shivaprasad PV.

Plant Mol Biol. 2017 Jul;94(4-5):381-397. doi: 10.1007/s11103-017-0613-9. Epub 2017 Apr 25.

PMID:
28444544
6.

Role of Tim17 Transmembrane Regions in Regulating the Architecture of Presequence Translocase and Mitochondrial DNA Stability.

Matta SK, Pareek G, Bankapalli K, Oblesha A, D'Silva P.

Mol Cell Biol. 2017 Mar 1;37(6). pii: e00491-16. doi: 10.1128/MCB.00491-16. Print 2017 Mar 15.

7.

Functional Diversity of Human Mitochondrial J-proteins Is Independent of Their Association with the Inner Membrane Presequence Translocase.

Sinha D, Srivastava S, D'Silva P.

J Biol Chem. 2016 Aug 12;291(33):17345-59. doi: 10.1074/jbc.M116.738146. Epub 2016 Jun 21.

8.

Immunity to hepatitis A and B persists for at least 15 years after immunisation of adolescents with a combined hepatitis A and B vaccine.

Beran J, Van Der Meeren O, Leyssen M, D'silva P.

Vaccine. 2016 May 23;34(24):2686-91. doi: 10.1016/j.vaccine.2016.04.033. Epub 2016 Apr 20.

9.

Robust glyoxalase activity of Hsp31, a ThiJ/DJ-1/PfpI family member protein, is critical for oxidative stress resistance in Saccharomyces cerevisiae.

Bankapalli K, Saladi S, Awadia SS, Goswami AV, Samaddar M, D'Silva P.

J Biol Chem. 2015 Oct 30;290(44):26491-507. doi: 10.1074/jbc.M115.673624. Epub 2015 Sep 14.

10.

Mapping Key Residues of ISD11 Critical for NFS1-ISD11 Subcomplex Stability: IMPLICATIONS IN THE DEVELOPMENT OF MITOCHONDRIAL DISORDER, COXPD19.

Saha PP, Srivastava S, Kumar S K P, Sinha D, D'Silva P.

J Biol Chem. 2015 Oct 23;290(43):25876-90. doi: 10.1074/jbc.M115.678508. Epub 2015 Sep 4.

11.

A Pd8 Tetrafacial Molecular Barrel as Carrier for Water Insoluble Fluorophore.

Roy B, Ghosh AK, Srivastava S, D'Silva P, Mukherjee PS.

J Am Chem Soc. 2015 Sep 23;137(37):11916-9. doi: 10.1021/jacs.5b08008. Epub 2015 Sep 10.

PMID:
26340646
12.

Highly Efficient Glutathione Peroxidase and Peroxiredoxin Mimetics Protect Mammalian Cells against Oxidative Damage.

Bhowmick D, Srivastava S, D'Silva P, Mugesh G.

Angew Chem Int Ed Engl. 2015 Jul 13;54(29):8449-53. doi: 10.1002/anie.201502430. Epub 2015 Jun 1.

PMID:
26032473
13.

An antioxidant nanozyme that uncovers the cytoprotective potential of vanadia nanowires.

Vernekar AA, Sinha D, Srivastava S, Paramasivam PU, D'Silva P, Mugesh G.

Nat Commun. 2014 Nov 21;5:5301. doi: 10.1038/ncomms6301.

PMID:
25412933
14.

Magmas functions as a ROS regulator and provides cytoprotection against oxidative stress-mediated damages.

Srivastava S, Sinha D, Saha PP, Marthala H, D'Silva P.

Cell Death Dis. 2014 Aug 28;5:e1394. doi: 10.1038/cddis.2014.355.

15.

Role of the loop L4,5 in allosteric regulation in mtHsp70s: in vivo significance of domain communication and its implications in protein translocation.

Samaddar M, Goswami AV, Purushotham J, Hegde P, D'Silva P.

Mol Biol Cell. 2014 Jul 15;25(14):2129-42. doi: 10.1091/mbc.E14-03-0821. Epub 2014 May 14.

16.

Unraveling the intricate organization of mammalian mitochondrial presequence translocases: existence of multiple translocases for maintenance of mitochondrial function.

Sinha D, Srivastava S, Krishna L, D'Silva P.

Mol Cell Biol. 2014 May;34(10):1757-75. doi: 10.1128/MCB.01527-13. Epub 2014 Mar 17.

17.

Chaperoning mitochondrial permeability transition: regulation of transition pore complex by a J-protein, DnaJC15.

Sinha D, D'Silva P.

Cell Death Dis. 2014 Mar 6;5:e1101. doi: 10.1038/cddis.2014.72.

18.

The presence of multiple cellular defects associated with a novel G50E iron-sulfur cluster scaffold protein (ISCU) mutation leads to development of mitochondrial myopathy.

Saha PP, Kumar SK, Srivastava S, Sinha D, Pareek G, D'Silva P.

J Biol Chem. 2014 Apr 11;289(15):10359-77. doi: 10.1074/jbc.M113.526665. Epub 2014 Feb 26.

19.

Are medical students inclined to do research?".

Jimmy R, Palatty PL, D'Silva P, Baliga MS, Singh A.

J Clin Diagn Res. 2013 Dec;7(12):2892-5. doi: 10.7860/JCDR/2013/6698.3786. Epub 2013 Dec 15.

20.

Molecular insights revealing interaction of Tim23 and channel subunits of presequence translocase.

Pareek G, Krishnamoorthy V, D'Silva P.

Mol Cell Biol. 2013 Dec;33(23):4641-59. doi: 10.1128/MCB.00876-13. Epub 2013 Sep 23.

21.

Rapid characterization of hydrogen exchange in proteins.

Thakur A, Chandra K, Dubey A, D'Silva P, Atreya HS.

Angew Chem Int Ed Engl. 2013 Feb 25;52(9):2440-3. doi: 10.1002/anie.201206828. Epub 2013 Jan 22.

PMID:
23341333
22.

HSPIR: a manually annotated heat shock protein information resource.

R RK, N S N, S P A, Sinha D, Veedin Rajan VB, Esthaki VK, D'Silva P.

Bioinformatics. 2012 Nov 1;28(21):2853-5. doi: 10.1093/bioinformatics/bts520. Epub 2012 Aug 24.

23.

Enhanced J-protein interaction and compromised protein stability of mtHsp70 variants lead to mitochondrial dysfunction in Parkinson's disease.

Goswami AV, Samaddar M, Sinha D, Purushotham J, D'Silva P.

Hum Mol Genet. 2012 Aug 1;21(15):3317-32. doi: 10.1093/hmg/dds162. Epub 2012 Apr 27.

24.

Structure and mechanistic insights into novel iron-mediated moonlighting functions of human J-protein cochaperone, Dph4.

Thakur A, Chitoor B, Goswami AV, Pareek G, Atreya HS, D'Silva P.

J Biol Chem. 2012 Apr 13;287(16):13194-205. doi: 10.1074/jbc.M112.339655. Epub 2012 Feb 24.

25.

Primary sequence that determines the functional overlap between mitochondrial heat shock protein 70 Ssc1 and Ssc3 of Saccharomyces cerevisiae.

Pareek G, Samaddar M, D'Silva P.

J Biol Chem. 2011 May 27;286(21):19001-13. doi: 10.1074/jbc.M110.197434. Epub 2011 Apr 7.

26.

Amino acid selective unlabeling for sequence specific resonance assignments in proteins.

Krishnarjuna B, Jaipuria G, Thakur A, D'Silva P, Atreya HS.

J Biomol NMR. 2011 Jan;49(1):39-51. doi: 10.1007/s10858-010-9459-z. Epub 2010 Dec 9.

27.

High-resolution methyl edited GFT NMR experiments for protein resonance assignments and structure determination.

Jaipuria G, Thakur A, D'Silva P, Atreya HS.

J Biomol NMR. 2010 Nov;48(3):137-45. doi: 10.1007/s10858-010-9444-6. Epub 2010 Sep 14.

PMID:
20838855
28.

Outcome of children with sickle cell disease admitted to intensive care - a single institution experience.

Bartram JL, Thein SL, Gardner K, Egberongbe Y, D'Silva P, Height SE, Dick MC, O'Driscoll S, Rees DC.

Br J Haematol. 2010 Sep;150(5):614-7. doi: 10.1111/j.1365-2141.2010.08272.x. Epub 2010 Jun 15.

PMID:
20560966
29.

Understanding the functional interplay between mammalian mitochondrial Hsp70 chaperone machine components.

Goswami AV, Chittoor B, D'Silva P.

J Biol Chem. 2010 Jun 18;285(25):19472-82. doi: 10.1074/jbc.M110.105957. Epub 2010 Apr 14.

30.

Role of Magmas in protein transport and human mitochondria biogenesis.

Sinha D, Joshi N, Chittoor B, Samji P, D'Silva P.

Hum Mol Genet. 2010 Apr 1;19(7):1248-62. doi: 10.1093/hmg/ddq002. Epub 2010 Jan 6.

31.

Arabidopsis thaliana J-class heat shock proteins: cellular stress sensors.

Rajan VB, D'Silva P.

Funct Integr Genomics. 2009 Nov;9(4):433-46. doi: 10.1007/s10142-009-0132-0. Epub 2009 Jul 25. Review.

PMID:
19633874
32.

Interaction of the J-protein heterodimer Pam18/Pam16 of the mitochondrial import motor with the translocon of the inner membrane.

D'Silva PR, Schilke B, Hayashi M, Craig EA.

Mol Biol Cell. 2008 Jan;19(1):424-32. Epub 2007 Nov 14.

33.

Evolution of mitochondrial chaperones utilized in Fe-S cluster biogenesis.

Schilke B, Williams B, Knieszner H, Pukszta S, D'Silva P, Craig EA, Marszalek J.

Curr Biol. 2006 Aug 22;16(16):1660-5.

34.

An essential connection: link between Hsp70's domains at last.

D'Silva P, Marszalek J, Craig EA.

Mol Cell. 2005 Nov 23;20(4):493-4.

35.

Role of Pam16's degenerate J domain in protein import across the mitochondrial inner membrane.

D'Silva PR, Schilke B, Walter W, Craig EA.

Proc Natl Acad Sci U S A. 2005 Aug 30;102(35):12419-24. Epub 2005 Aug 16.

36.

Compensation for a defective interaction of the hsp70 ssq1 with the mitochondrial Fe-S cluster scaffold isu.

Knieszner H, Schilke B, Dutkiewicz R, D'Silva P, Cheng S, Ohlson M, Craig EA, Marszalek J.

J Biol Chem. 2005 Aug 12;280(32):28966-72. Epub 2005 Jun 15.

37.

Regulated interactions of mtHsp70 with Tim44 at the translocon in the mitochondrial inner membrane.

D'Silva P, Liu Q, Walter W, Craig EA.

Nat Struct Mol Biol. 2004 Nov;11(11):1084-91. Epub 2004 Oct 17.

PMID:
15489862
38.

J protein cochaperone of the mitochondrial inner membrane required for protein import into the mitochondrial matrix.

D'Silva PD, Schilke B, Walter W, Andrew A, Craig EA.

Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):13839-44. Epub 2003 Nov 6.

39.

Regulated cycling of mitochondrial Hsp70 at the protein import channel.

Liu Q, D'Silva P, Walter W, Marszalek J, Craig EA.

Science. 2003 Apr 4;300(5616):139-41.

40.

Organization of diphtheria toxin in membranes. A hydrophobic photolabeling study.

D'Silva PR, Lala AK.

J Biol Chem. 2000 Apr 21;275(16):11771-7. Erratum in: J Biol Chem 2000 Sep 1;275(35):27500.

42.

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