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Items: 47

1.

Generation of stable PDX derived cell lines using conditional reprogramming.

Borodovsky A, McQuiston TJ, Stetson D, Ahmed A, Whitston D, Zhang J, Grondine M, Lawson D, Challberg SS, Zinda M, Pollok BA, Dougherty BA, D'Cruz CM.

Mol Cancer. 2017 Dec 6;16(1):177. doi: 10.1186/s12943-017-0745-1.

2.

Effective combination therapies in preclinical endocrine resistant breast cancer models harboring ER mutations.

Ladd B, Mazzola AM, Bihani T, Lai Z, Bradford J, Collins M, Barry E, Goeppert AU, Weir HM, Hearne K, Renshaw JG, Mohseni M, Hurt E, Jalla S, Bao H, Hollingsworth R, Reimer C, Zinda M, Fawell S, D'Cruz CM.

Oncotarget. 2016 Aug 23;7(34):54120-54136. doi: 10.18632/oncotarget.10852.

3.

Acquired savolitinib resistance in non-small cell lung cancer arises via multiple mechanisms that converge on MET-independent mTOR and MYC activation.

Henry RE, Barry ER, Castriotta L, Ladd B, Markovets A, Beran G, Ren Y, Zhou F, Adam A, Zinda M, Reimer C, Qing W, Su W, Clark E, D'Cruz CM, Schuller AG.

Oncotarget. 2016 Sep 6;7(36):57651-57670. doi: 10.18632/oncotarget.10859.

4.

AZD9496: An Oral Estrogen Receptor Inhibitor That Blocks the Growth of ER-Positive and ESR1-Mutant Breast Tumors in Preclinical Models.

Weir HM, Bradbury RH, Lawson M, Rabow AA, Buttar D, Callis RJ, Curwen JO, de Almeida C, Ballard P, Hulse M, Donald CS, Feron LJ, Karoutchi G, MacFaul P, Moss T, Norman RA, Pearson SE, Tonge M, Davies G, Walker GE, Wilson Z, Rowlinson R, Powell S, Sadler C, Richmond G, Ladd B, Pazolli E, Mazzola AM, D'Cruz C, De Savi C.

Cancer Res. 2016 Jun 1;76(11):3307-18. doi: 10.1158/0008-5472.CAN-15-2357. Epub 2016 Mar 28.

5.

Whole transcriptome profiling of patient-derived xenograft models as a tool to identify both tumor and stromal specific biomarkers.

Bradford JR, Wappett M, Beran G, Logie A, Delpuech O, Brown H, Boros J, Camp NJ, McEwen R, Mazzola AM, D'Cruz C, Barry ST.

Oncotarget. 2016 Apr 12;7(15):20773-87. doi: 10.18632/oncotarget.8014.

6.

The Legend of the Pediatric Pathology Club and its Infamous Knights (with Apologies to Monty Python and the Holy Grail).

D'Cruz C.

Pediatr Dev Pathol. 2015 Nov-Dec;18(6):522-3. doi: 10.2350/15-10-1718-OA.1. Epub 2015 Dec 23. No abstract available.

PMID:
26699242
7.

AZD2014, an Inhibitor of mTORC1 and mTORC2, Is Highly Effective in ER+ Breast Cancer When Administered Using Intermittent or Continuous Schedules.

Guichard SM, Curwen J, Bihani T, D'Cruz CM, Yates JW, Grondine M, Howard Z, Davies BR, Bigley G, Klinowska T, Pike KG, Pass M, Chresta CM, Polanska UM, McEwen R, Delpuech O, Green S, Cosulich SC.

Mol Cancer Ther. 2015 Nov;14(11):2508-18. doi: 10.1158/1535-7163.MCT-15-0365. Epub 2015 Sep 10.

8.

Tumors with AKT1E17K Mutations Are Rational Targets for Single Agent or Combination Therapy with AKT Inhibitors.

Davies BR, Guan N, Logie A, Crafter C, Hanson L, Jacobs V, James N, Dudley P, Jacques K, Ladd B, D'Cruz CM, Zinda M, Lindemann J, Kodaira M, Tamura K, Jenkins EL.

Mol Cancer Ther. 2015 Nov;14(11):2441-51. doi: 10.1158/1535-7163.MCT-15-0230. Epub 2015 Sep 8.

9.

Validation of a predictive modeling approach to demonstrate the relative efficacy of three different schedules of the AKT inhibitor AZD5363.

Yates JW, Dudley P, Cheng J, D'Cruz C, Davies BR.

Cancer Chemother Pharmacol. 2015 Aug;76(2):343-56. doi: 10.1007/s00280-015-2795-7. Epub 2015 Jun 20.

PMID:
26092323
10.

The MET Inhibitor AZD6094 (Savolitinib, HMPL-504) Induces Regression in Papillary Renal Cell Carcinoma Patient-Derived Xenograft Models.

Schuller AG, Barry ER, Jones RD, Henry RE, Frigault MM, Beran G, Linsenmayer D, Hattersley M, Smith A, Wilson J, Cairo S, Déas O, Nicolle D, Adam A, Zinda M, Reimer C, Fawell SE, Clark EA, D'Cruz CM.

Clin Cancer Res. 2015 Jun 15;21(12):2811-9. doi: 10.1158/1078-0432.CCR-14-2685. Epub 2015 Mar 16.

11.

Resistance to everolimus driven by epigenetic regulation of MYC in ER+ breast cancers.

Bihani T, Ezell SA, Ladd B, Grosskurth SE, Mazzola AM, Pietras M, Reimer C, Zinda M, Fawell S, D'Cruz CM.

Oncotarget. 2015 Feb 10;6(4):2407-20.

12.

Inhibition of PI3Kβ signaling with AZD8186 inhibits growth of PTEN-deficient breast and prostate tumors alone and in combination with docetaxel.

Hancox U, Cosulich S, Hanson L, Trigwell C, Lenaghan C, Ellston R, Dry H, Crafter C, Barlaam B, Fitzek M, Smith PD, Ogilvie D, D'Cruz C, Castriotta L, Wedge SR, Ward L, Powell S, Lawson M, Davies BR, Harrington EA, Foster E, Cumberbatch M, Green S, Barry ST.

Mol Cancer Ther. 2015 Jan;14(1):48-58. doi: 10.1158/1535-7163.MCT-14-0406. Epub 2014 Nov 14.

13.

Learning curve for endobronchial ultrasound‑guided transbronchial needle aspiration: experience of a community‑based teaching hospital.

Wang H, D'Cruz C, Yam DC, Dilla LM, Tsang P.

Mol Med Rep. 2014 Nov;10(5):2441-6. doi: 10.3892/mmr.2014.2533. Epub 2014 Sep 3.

PMID:
25189939
14.

Follow-up of breast papillary lesion on core needle biopsy: experience in African-American population.

Wang H, Tsang P, D'Cruz C, Clarke K.

Diagn Pathol. 2014 Apr 24;9:86. doi: 10.1186/1746-1596-9-86.

15.

Thyroid papillary carcinoma in a 3-year-old American boy with a family history of thyroid cancer: a case report and literature review.

Khara L, Silverman A, Bethel C, D'Cruz C, Sun X.

J Pediatr Hematol Oncol. 2010 Apr;32(3):e118-21. doi: 10.1097/MPH.0b013e3181c97c57. Review.

PMID:
20216232
16.

Singular value decomposition-based regression identifies activation of endogenous signaling pathways in vivo.

Liu Z, Wang M, Alvarez JV, Bonney ME, Chen CC, D'Cruz C, Pan TC, Tadesse MG, Chodosh LA.

Genome Biol. 2008;9(12):R180. doi: 10.1186/gb-2008-9-12-r180. Epub 2008 Dec 18.

17.

Finite de Finetti theorem for infinite-dimensional systems.

D'Cruz C, Osborne TJ, Schack R.

Phys Rev Lett. 2007 Apr 20;98(16):160406. Epub 2007 Apr 19.

PMID:
17501401
18.

c-Myc transforms human mammary epithelial cells through repression of the Wnt inhibitors DKK1 and SFRP1.

Cowling VH, D'Cruz CM, Chodosh LA, Cole MD.

Mol Cell Biol. 2007 Jul;27(14):5135-46. Epub 2007 May 7.

19.

Homozygous transthyretin mutation in an African American Male.

Jacob EK, Edwards WD, Zucker M, D'Cruz C, Seshan SV, Crow FW, Highsmith WE.

J Mol Diagn. 2007 Feb;9(1):127-31.

20.

Lymphoepithelioma-like carcinoma of the vulva.

Niu W, Heller DS, D'Cruz C.

J Low Genit Tract Dis. 2003 Jul;7(3):184-6.

PMID:
17051066
21.

Hormone-induced protection against mammary tumorigenesis is conserved in multiple rat strains and identifies a core gene expression signature induced by pregnancy.

Blakely CM, Stoddard AJ, Belka GK, Dugan KD, Notarfrancesco KL, Moody SE, D'Cruz CM, Chodosh LA.

Cancer Res. 2006 Jun 15;66(12):6421-31. Erratum in: Cancer Res. 2007 Jan 15;67(2):844-6.

22.

Cardiac hemangioma of the right atrium in a neonate: fetal management and expedited surgical resection.

Sebastian V, Einzig S, D'Cruz C, Costello C, Kula M, Campbell A.

Images Paediatr Cardiol. 2005 Oct;7(4):5-9.

23.

Developmental stage determines the effects of MYC in the mammary epithelium.

Blakely CM, Sintasath L, D'Cruz CM, Hahn KT, Dugan KD, Belka GK, Chodosh LA.

Development. 2005 Mar;132(5):1147-60. Epub 2005 Feb 2. Erratum in: Development. 2005 Mar;132(6):1475.

24.

Pathologic quiz case: a newborn with a midline buccal mucosa mass. Congenital gingival granular cell tumor (congenital epulis).

Godra A, D'Cruz CA, Labat MF, Isaacson G.

Arch Pathol Lab Med. 2004 May;128(5):585-6. No abstract available.

PMID:
15086295
25.

Pathologic quiz case: a 5-day-old boy with hydrops fetalis. Mucolipidoses I (Sialidosis III).

Godra A, Kim DU, D'Cruz C.

Arch Pathol Lab Med. 2003 Aug;127(8):1051-2. No abstract available.

PMID:
12873188
26.

Persistent parity-induced changes in growth factors, TGF-beta3, and differentiation in the rodent mammary gland.

D'Cruz CM, Moody SE, Master SR, Hartman JL, Keiper EA, Imielinski MB, Cox JD, Wang JY, Ha SI, Keister BA, Chodosh LA.

Mol Endocrinol. 2002 Sep;16(9):2034-51.

PMID:
12198241
27.

Functional microarray analysis of mammary organogenesis reveals a developmental role in adaptive thermogenesis.

Master SR, Hartman JL, D'Cruz CM, Moody SE, Keiper EA, Ha SI, Cox JD, Belka GK, Chodosh LA.

Mol Endocrinol. 2002 Jun;16(6):1185-203.

PMID:
12040007
28.

Transcendental meditation, hypertension and heart disease.

King MS, Carr T, D'Cruz C.

Aust Fam Physician. 2002 Feb;31(2):164-8. Review.

PMID:
11917830
29.

Aluminum phagocytosis in quadriceps muscle following vaccination in children: relationship to macrophagic myofasciitis.

Lacson AG, D'Cruz CA, Gilbert-Barness E, Sharer L, Jacinto S, Cuenca R.

Pediatr Dev Pathol. 2002 Mar-Apr;5(2):151-8.

PMID:
11910509
30.

c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations.

D'Cruz CM, Gunther EJ, Boxer RB, Hartman JL, Sintasath L, Moody SE, Cox JD, Ha SI, Belka GK, Golant A, Cardiff RD, Chodosh LA.

Nat Med. 2001 Feb;7(2):235-9.

PMID:
11175856
31.

Mammary gland development, reproductive history, and breast cancer risk.

Chodosh LA, D'Cruz CM, Gardner HP, Ha SI, Marquis ST, Rajan JV, Stairs DB, Wang JY, Wang M.

Cancer Res. 1999 Apr 1;59(7 Suppl):1765-1771s; discussion 1771s-1772s. Review.

PMID:
10197594
32.

Production and characterization of a soluble, active form of Tva, the subgroup A avian sarcoma and leukosis virus receptor.

Balliet JW, Berson J, D'Cruz CM, Huang J, Crane J, Gilbert JM, Bates P.

J Virol. 1999 Apr;73(4):3054-61.

33.

Extensive vascular calcification in a patient with perinatally acquired AIDS.

Marquis JR, D'Cruz C.

Pediatr Radiol. 1996;26(5):365-6.

PMID:
8657470
34.

Molecular assays for chromosomal translocations in the diagnosis of pediatric soft tissue sarcomas.

Barr FG, Chatten J, D'Cruz CM, Wilson AE, Nauta LE, Nycum LM, Biegel JA, Womer RB.

JAMA. 1995 Feb 15;273(7):553-7.

PMID:
7530783
35.

Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma.

Davis RJ, D'Cruz CM, Lovell MA, Biegel JA, Barr FG.

Cancer Res. 1994 Jun 1;54(11):2869-72.

36.
37.

Sinus histiocytosis massive lymphadenopathy syndrome: histogenesis of the hepatic lesion.

Brown RE, D'Cruz CA.

Ann Clin Lab Sci. 1987 May-Jun;17(3):162-70.

PMID:
3606023
38.

Acardiac anomaly: review of the subject with case report and emphasis on practical sonography.

Gibson JY, D'Cruz CA, Patel RB, Palmer SM.

J Clin Ultrasound. 1986 Sep;14(7):541-5. Review.

PMID:
2945834
39.

Osseous pseudotumor. The sole manifestation of sinus histiocytosis with massive lymphadenopathy.

Lewin JR, Das SK, Blumenthal BI, D'Cruz C, Patel RB, Howell GE.

Am J Clin Pathol. 1985 Oct;84(4):547-50.

PMID:
4036885
40.

Reverse discordant behavior in microfollicular adenoma of thyroid. Case report.

Patel BR, D'Cruz CA.

Clin Nucl Med. 1985 Sep;10(9):653-4.

PMID:
2998673
41.

Necrotizing enterocolitis can be caused by polycythemic hyperviscosity in the newborn dog.

LeBlanc MH, D'Cruz C, Pate K.

J Pediatr. 1984 Nov;105(5):804-9.

PMID:
6502314
42.

Unusual scintiscan appearance of Meckel's diverticulum. A case report.

Patel BR, D'Cruz CA, McCay MB.

Clin Nucl Med. 1984 Oct;9(10):554-5.

PMID:
6091970
43.

Amyotrophic cerebellar hypoplasia: a specific form of infantile spinal atrophy.

de León GA, Grover WD, D'Cruz CA.

Acta Neuropathol. 1984;63(4):282-6.

PMID:
6475488
44.

Veno-occlusive disease of the liver in children following chemotherapy for acute myelocytic leukemia.

D'Cruz CA, Wimmer RS, Harcke HT, Huff DS, Naiman JL.

Cancer. 1983 Nov 15;52(10):1803-7.

PMID:
6578867
45.

Radiologic seminar CCXXXIII: Visualization of Meckel's diverticulum by radionuclide imaging.

Patel BR, D'Cruz CA, Sanders JA.

J Miss State Med Assoc. 1983 Nov;24(11):305-7. No abstract available.

PMID:
6606051
46.

Sonographic diagnosis of cervical teratoma in utero.

Patel RB, Gibson JY, D'Cruz CA, Burkhalter JL.

AJR Am J Roentgenol. 1982 Dec;139(6):1220-2. No abstract available.

PMID:
6983274
47.

Intracranial malignancy in patients with bilateral retinoblastoma.

Donoso LA, Shields JA, Felberg NT, Martyn LJ, Truex RC Jr, D'Cruz CA.

Retina. 1981;1(1):67-74.

PMID:
15633409

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