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Decoding the metabolic landscape of pathophysiological stress-induced cell death in anucleate red blood cells.

Nemkov T, Qadri SM, Sheffield WP, D'Alessandro A.

Blood Transfus. 2020 Feb 28:1-16. doi: 10.2450/2020.0256-19. [Epub ahead of print]


Trans-stomal single-port laparoscopic Hartmann's reversal is an efficacious and efficient procedure: a case-controlled study.

D'Alessandro A, Gumbs AA, Cartillone M, Elkary N, Chahine E, Chouillard E.

Tech Coloproctol. 2020 Mar 21. doi: 10.1007/s10151-020-02166-0. [Epub ahead of print]


Hypoxic Activation of G6PD Controls the Expression of Genes Involved in the Pathogenesis of Pulmonary Hypertension Through the Regulation of DNA Methylation.

Joshi SR, Kitagawa A, Jacob C, Hashimoto R, Dhagia V, Ramesh A, Zheng C, Zhang H, Jordan A, Waddell I, Leopold JA, Hu CJ, McMurtry IF, D'Alessandro A, Stenmark KR, Gupte SA.

Am J Physiol Lung Cell Mol Physiol. 2020 Mar 11. doi: 10.1152/ajplung.00001.2020. [Epub ahead of print]


Erythrocyte adaptive metabolic reprogramming under physiological and pathological hypoxia.

D'Alessandro A, Xia Y.

Curr Opin Hematol. 2020 Mar 5. doi: 10.1097/MOH.0000000000000574. [Epub ahead of print]


Publisher Correction: Stable isotope metabolomics of pulmonary artery smooth muscle and endothelial cells in pulmonary hypertension and with TGF-beta treatment.

Hernandez-Saavedra D, Sanders L, Freeman S, Reisz JA, Lee MH, Mickael C, Kumar R, Kassa B, Gu S, D' Alessandro A, Stenmark KR, Tuder RM, Graham BB.

Sci Rep. 2020 Mar 4;10(1):4349. doi: 10.1038/s41598-020-60500-w.


Study of vessel density in adult-onset foveomacular vitelliform dystrophy with Optical Coherence Tomography Angiography.

Cennamo G, Montorio D, Mirra F, Comune C, D'Alessandro A, Tranfa F.

Photodiagnosis Photodyn Ther. 2020 Feb 29:101702. doi: 10.1016/j.pdpdt.2020.101702. [Epub ahead of print]


Gene-Diet Interactions: Dietary Rescue of Metabolic Defects in spen-depleted Drosophila melanogaster.

Gillette CM, Hazegh KE, Nemkov T, Stefanoni D, D'Alessandro A, Taliaferro JM, Reis T.

Genetics. 2020 Feb 27. pii: genetics.303015.2019. doi: 10.1534/genetics.119.303015. [Epub ahead of print]


Hypoxic storage of red blood cells improves metabolism and post-transfusion recovery.

DʼAlessandro A, Yoshida T, Nestheide S, Nemkov T, Stocker S, Stefanoni D, Mohmoud F, Rugg N, Dunham A, Cancelas JA.

Transfusion. 2020 Feb 27. doi: 10.1111/trf.15730. [Epub ahead of print]


MDM2 and MDMX promote ferroptosis by PPARα-mediated lipid remodeling.

Venkatesh D, O'Brien NA, Zandkarimi F, Tong DR, Stokes ME, Dunn DE, Kengmana ES, Aron AT, Klein AM, Csuka JM, Moon SH, Conrad M, Chang CJ, Lo DC, D'Alessandro A, Prives C, Stockwell BR.

Genes Dev. 2020 Feb 20. doi: 10.1101/gad.334219.119. [Epub ahead of print]


A Weigh-in-Motion Characterization Algorithm for Smart Pavements Based on Conductive Cementitious Materials.

Birgin HB, Laflamme S, D'Alessandro A, Garcia-Macias E, Ubertini F.

Sensors (Basel). 2020 Jan 24;20(3). pii: E659. doi: 10.3390/s20030659.


Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia.

Pei S, Pollyea DA, Gustafson A, Stevens BM, Minhajuddin M, Fu R, Riemondy KA, Gillen AE, Sheridan RM, Kim J, Costello JC, Amaya ML, Inguva A, Winters A, Ye H, Krug A, Jones CL, Adane B, Khan N, Ponder J, Schowinsky J, Abbott D, Hammes A, Myers JR, Ashton JM, Nemkov T, D'Alessandro A, Gutman JA, Ramsey HE, Savona MR, Smith CA, Jordan CT.

Cancer Discov. 2020 Jan 23. doi: 10.1158/2159-8290.CD-19-0710. [Epub ahead of print]


Donor glucose-6-phosphate dehydrogenase deficiency decreases blood quality for transfusion.

Francis RO, D'Alessandro A, Eisenberger A, Soffing M, Yeh R, Coronel E, Sheikh A, Rapido F, La Carpia F, Reisz JA, Gehrke S, Nemkov T, Thomas T, Schwartz J, Divgi C, Kessler D, Shaz BH, Ginzburg Y, Zimring JC, Spitalnik SL, Hod EA.

J Clin Invest. 2020 Mar 23. pii: 133530. doi: 10.1172/JCI133530. [Epub ahead of print]


Methylglyoxal-Dependent Glycative Stress and Deregulation of SIRT1 Functional Network in the Ovary of PCOS Mice.

Emidio GD, Placidi M, Rea F, Rossi G, Falone S, Cristiano L, Nottola S, D'Alessandro AM, Amicarelli F, Palmerini MG, Tatone C.

Cells. 2020 Jan 14;9(1). pii: E209. doi: 10.3390/cells9010209.


Stable isotope metabolomics of pulmonary artery smooth muscle and endothelial cells in pulmonary hypertension and with TGF-beta treatment.

Hernandez-Saavedra D, Sanders L, Freeman S, Reisz JA, Lee MH, Mickael C, Kumar R, Kassa B, Gu S, D' Alessandro A, Stenmark KR, Tuder RM, Graham BB.

Sci Rep. 2020 Jan 15;10(1):413. doi: 10.1038/s41598-019-57200-5. Erratum in: Sci Rep. 2020 Mar 4;10(1):4349.


Targeted donor complement blockade after brain death prevents delayed graft function in a nonhuman primate model of kidney transplantation.

Danobeitia JS, Zens TJ, Chlebeck PJ, Zitur LJ, Reyes JA, Eerhart MJ, Coonen J, Capuano S, D'Alessandro AM, Torrealba JR, Burguete D, Brunner K, Van Amersfoort E, Ponstein Y, Van Kooten C, Jankowska-Gan E, Burlingham W, Sullivan J, Djamali A, Pozniak M, Yankol Y, Fernandez LA.

Am J Transplant. 2020 Jan 10. doi: 10.1111/ajt.15777. [Epub ahead of print]


Metabolic phenotypes of standard and cold-stored platelets.

D'Alessandro A, Thomas KA, Stefanoni D, Gamboni F, Shea SM, Reisz JA, Spinella PC.

Transfusion. 2019 Dec 27. doi: 10.1111/trf.15651. [Epub ahead of print]


Chemical-Sensory Traits of Fresh Cheese Made by Enzymatic Coagulation of Donkey Milk.

Faccia M, Gambacorta G, Martemucci G, Difonzo G, D'Alessandro AG.

Foods. 2019 Dec 23;9(1). pii: E16. doi: 10.3390/foods9010016.


Inflammation-Induced Alternative Pre-mRNA Splicing in Mouse Alveolar Macrophages.

Janssen WJ, Danhorn T, Harris C, Mould KJ, Lee FF, Hedin BR, D'Alessandro A, Leach SM, Alper S.

G3 (Bethesda). 2020 Feb 6;10(2):555-567. doi: 10.1534/g3.119.400935.


Male fetus susceptibility to maternal inflammation: C-reactive protein and brain development.

Hunter SK, Hoffman MC, D'Alessandro A, Noonan K, Wyrwa A, Freedman R, Law AJ.

Psychol Med. 2019 Dec 2:1-10. doi: 10.1017/S0033291719003313. [Epub ahead of print]


Short-term interleukin-37 treatment improves vascular endothelial function, endurance exercise capacity, and whole-body glucose metabolism in old mice.

Ballak DB, Brunt VE, Sapinsley ZJ, Ziemba BP, Richey JJ, Zigler MC, Johnson LC, Gioscia-Ryan RA, Culp-Hill R, Eisenmesser EZ, D'Alessandro A, Dinarello CA, Seals DR.

Aging Cell. 2020 Jan;19(1):e13074. doi: 10.1111/acel.13074. Epub 2019 Nov 21.


The plasma metabolome as a predictor of biological aging in humans.

Johnson LC, Parker K, Aguirre BF, Nemkov TG, D'Alessandro A, Johnson SA, Seals DR, Martens CR.

Geroscience. 2019 Dec;41(6):895-906. doi: 10.1007/s11357-019-00123-w. Epub 2019 Nov 9.


Red blood cell metabolism in Rhesus macaques and humans: comparative biology of blood storage.

Stefanoni D, Shin HKH, Baek JH, Champagne DP, Nemkov T, Thomas T, Francis RO, Zimring JC, Yoshida T, Reisz JA, Spitalnik SL, Buehler PW, D'Alessandro A.

Haematologica. 2019 Nov 7. pii: haematol.2019.229930. doi: 10.3324/haematol.2019.229930. [Epub ahead of print]


Drug Design Targeting T-Cell Factor-Driven Epithelial-Mesenchymal Transition as a Therapeutic Strategy for Colorectal Cancer.

Abraham AD, Esquer H, Zhou Q, Tomlinson N, Hamill BD, Abbott JM, Li L, Pike LA, Rinaldetti S, Ramirez DA, Lunghofer PJ, Gomez JD, Schaack J, Nemkov T, D'Alessandro A, Hansen KC, Gustafson DL, Messersmith WA, LaBarbera DV.

J Med Chem. 2019 Nov 27;62(22):10182-10203. doi: 10.1021/acs.jmedchem.9b01065. Epub 2019 Nov 18.


Prospective Study of Vessel Density by Optical Coherence Tomography Angiography After Intravitreal Bevacizumab in Exudative Age-Related Macular Degeneration.

Cennamo G, Montorio D, D'Alessandro A, Napolitano P, D'Andrea L, Tranfa F.

Ophthalmol Ther. 2020 Mar;9(1):77-85. doi: 10.1007/s40123-019-00221-0. Epub 2019 Oct 31.


Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors.

Powers RK, Culp-Hill R, Ludwig MP, Smith KP, Waugh KA, Minter R, Tuttle KD, Lewis HC, Rachubinski AL, Granrath RE, Carmona-Iragui M, Wilkerson RB, Kahn DE, Joshi M, Lleó A, Blesa R, Fortea J, D'Alessandro A, Costello JC, Sullivan KD, Espinosa JM.

Nat Commun. 2019 Oct 18;10(1):4766. doi: 10.1038/s41467-019-12739-9.


Predicting response to lisinopril in treating hypertension: a pilot study.

Sonn BJ, Saben JL, McWilliams G, Shelton SK, Flaten HK, D'Alessandro A, Monte AA.

Metabolomics. 2019 Oct 3;15(10):133. doi: 10.1007/s11306-019-1601-7.


Transfusional iron overload and intravenous iron infusions modify the mouse gut microbiota similarly to dietary iron.

La Carpia F, Wojczyk BS, Annavajhala MK, Rebbaa A, Culp-Hill R, D'Alessandro A, Freedberg DE, Uhlemann AC, Hod EA.

NPJ Biofilms Microbiomes. 2019 Sep 24;5:26. doi: 10.1038/s41522-019-0097-2. eCollection 2019.


Healthcare workers' knowledge, beliefs, and coverage regarding vaccinations in critical care units in Italy.

Napolitano F, Bianco A, D'Alessandro A, Papadopoli R, Angelillo IF.

Vaccine. 2019 Oct 31;37(46):6900-6906. doi: 10.1016/j.vaccine.2019.09.053. Epub 2019 Sep 26.


Production of cheese from donkey milk as influenced by addition of transglutaminase.

D'Alessandro AG, Martemucci G, Loizzo P, Faccia M.

J Dairy Sci. 2019 Dec;102(12):10867-10876. doi: 10.3168/jds.2019-16615. Epub 2019 Sep 25.


Runner With Abdominal Pain.

D'Alessandro AD, Smith AT, Binion TW, Shah KS.

Ann Emerg Med. 2019 Oct;74(4):491-508. doi: 10.1016/j.annemergmed.2019.03.034. No abstract available.


The metabolic time line of pancreatic cancer: Opportunities to improve early detection of adenocarcinoma.

Moore HB, Culp-Hill R, Reisz JA, Lawson PJ, Sauaia A, Schulick RD, Del Chiaro M, Nydam TL, Moore EE, Hansen KC, D'Alessandro A.

Am J Surg. 2019 Dec;218(6):1206-1212. doi: 10.1016/j.amjsurg.2019.08.015. Epub 2019 Aug 27.


Liquid crystal beyond displays: feature introduction.

Lin YH, Hu W, Lin TH, d'Alessandro A.

Opt Express. 2019 Jul 22;27(15):20785-20786. doi: 10.1364/OE.27.020785.


Skeletal muscle amino acid uptake is lower and alanine production is greater in late gestation intrauterine growth restricted fetal sheep hindlimb.

Chang EI, Wesolowski SR, Gilje EA, Baker PR 2nd, Reisz JA, D'Alessandro A, Hay WW Jr, Rozance PJ, Brown LD.

Am J Physiol Regul Integr Comp Physiol. 2019 Sep 4. doi: 10.1152/ajpregu.00115.2019. [Epub ahead of print]


Coordinate Regulation of Cholesterol and Bile Acid Metabolism by the Clock Modifier Nobiletin in Metabolically Challenged Old Mice.

Nohara K, Nemkov T, D'Alessandro A, Yoo SH, Chen Z.

Int J Mol Sci. 2019 Sep 1;20(17). pii: E4281. doi: 10.3390/ijms20174281.


Transfusion of Anaerobically or Conventionally Stored Blood After Hemorrhagic Shock.

Williams AT, Jani VP, Nemkov T, Lucas A, Yoshida T, Dunham A, D'Alessandro A, Cabrales P.

Shock. 2020 Mar;53(3):352-362. doi: 10.1097/SHK.0000000000001386.


Nobiletin fortifies mitochondrial respiration in skeletal muscle to promote healthy aging against metabolic challenge.

Nohara K, Mallampalli V, Nemkov T, Wirianto M, Yang J, Ye Y, Sun Y, Han L, Esser KA, Mileykovskaya E, D'Alessandro A, Green CB, Takahashi JS, Dowhan W, Yoo SH, Chen Z.

Nat Commun. 2019 Aug 28;10(1):3923. doi: 10.1038/s41467-019-11926-y.


Personalised Transfusion Medicine.

D'Alessandro A, Liumbruno G.

Blood Transfus. 2019 Jul;17(4):255-257. doi: 10.2450/2019.0142-19. No abstract available.


Metabolic impact of red blood cell exchange with rejuvenated red blood cells in sickle cell patients.

Gehrke S, Shah N, Gamboni F, Kamyszek R, Srinivasan AJ, Gray A, Landrigan M, Welsby I, D'Alessandro A.

Transfusion. 2019 Oct;59(10):3102-3112. doi: 10.1111/trf.15467. Epub 2019 Aug 5.


Interaction of maternal choline levels and prenatal Marijuana's effects on the offspring.

Hoffman MC, Hunter SK, D'Alessandro A, Noonan K, Wyrwa A, Freedman R.

Psychol Med. 2019 Jul 31:1-11. doi: 10.1017/S003329171900179X. [Epub ahead of print]


Differences in Steap3 expression are a mechanism of genetic variation of RBC storage and oxidative damage in mice.

Howie HL, Hay AM, de Wolski K, Waterman H, Lebedev J, Fu X, Culp-Hill R, D'Alessandro A, Gorham JD, Ranson MS, Roback JD, Thomson PC, Zimring JC.

Blood Adv. 2019 Aug 13;3(15):2272-2285. doi: 10.1182/bloodadvances.2019000605.


A Review of the Capacitive MEMS for Seismology.

D'Alessandro A, Scudero S, Vitale G.

Sensors (Basel). 2019 Jul 12;19(14). pii: E3093. doi: 10.3390/s19143093. Review.


TNF-α-driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging.

Davizon-Castillo P, McMahon B, Aguila S, Bark D, Ashworth K, Allawzi A, Campbell RA, Montenont E, Nemkov T, D'Alessandro A, Clendenen N, Shih L, Sanders NA, Higa K, Cox A, Padilla-Romo Z, Hernandez G, Wartchow E, Trahan GD, Nozik-Grayck E, Jones K, Pietras EM, DeGregori J, Rondina MT, Di Paola J.

Blood. 2019 Aug 29;134(9):727-740. doi: 10.1182/blood.2019000200. Epub 2019 Jul 16.


Gastric schwannoma misdiagnosed as a GIST.

Peltrini R, Greco PA, Nasto RA, D'Alessandro A, Iacobelli A, Insabato L, Bucci L.

Acta Chir Belg. 2019 Dec;119(6):411-413. doi: 10.1080/00015458.2019.1642597. Epub 2019 Jul 16. No abstract available.


Metabolic Systems Analysis of Shock-Induced Endotheliopathy (SHINE) in Trauma: A New Research Paradigm.

Henriksen HH, McGarrity S, SigurÐardóttir RS, Nemkov T, D'Alessandro A, Palsson BO, Stensballe J, Wade CE, Rolfsson Ó, Johansson PI.

Ann Surg. 2019 Jun 26. doi: 10.1097/SLA.0000000000003307. [Epub ahead of print]


Cell-Intrinsic Glycogen Metabolism Supports Early Glycolytic Reprogramming Required for Dendritic Cell Immune Responses.

Thwe PM, Pelgrom LR, Cooper R, Beauchamp S, Reisz JA, D'Alessandro A, Everts B, Amiel E.

Cell Metab. 2019 Jul 2;30(1):225. doi: 10.1016/j.cmet.2019.05.017. No abstract available.


Author Correction: The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD.

Soderborg TK, Clark SE, Mulligan CE, Janssen RC, Babcock L, Ir D, Young B, Krebs NF, Lemas DJ, Johnson LK, Weir T, Lenz LL, Frank DN, Hernandez TL, Kuhn KA, D'Alessandro A, Barbour LA, El Kasmi KC, Friedman JE.

Nat Commun. 2019 Jul 1;10(1):2965. doi: 10.1038/s41467-019-10943-1.


Circadian period 2: a missing beneficial factor in sickle cell disease by lowering pulmonary inflammation, iron overload, and mortality.

Adebiyi MG, Zhao Z, Ye Y, Manalo J, Hong Y, Lee CC, Xian W, McKeon F, Culp-Hill R, D' Alessandro A, Kellems RE, Yoo SH, Han L, Xia Y.

FASEB J. 2019 Sep;33(9):10528-10537. doi: 10.1096/fj.201900246RR. Epub 2019 Jun 29.


Parabiosis Incompletely Reverses Aging-Induced Metabolic Changes and Oxidant Stress in Mouse Red Blood Cells.

Morrison EJ, Champagne DP, Dzieciatkowska M, Nemkov T, Zimring JC, Hansen KC, Guan F, Huffman DM, Santambrogio L, D'Alessandro A.

Nutrients. 2019 Jun 14;11(6). pii: E1337. doi: 10.3390/nu11061337.


Multiple seasonality in soil radon time series.

Siino M, Scudero S, Cannelli V, Piersanti A, D'Alessandro A.

Sci Rep. 2019 Jun 13;9(1):8610. doi: 10.1038/s41598-019-44875-z.


Protect, repair, destroy or sacrifice: a role of oxidative stress biology in inter-donor variability of blood storage?

D'Alessandro A, Hansen KC, Eisenmesser EZ, Zimring JC.

Blood Transfus. 2019 Jul;17(4):281-288. doi: 10.2450/2019.0072-19. Epub 2019 Jun 6. Review.

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