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Items: 10

1.

Ptpn6 inhibits caspase-8- and Ripk3/Mlkl-dependent inflammation.

Speir M, Nowell CJ, Chen AA, O'Donnell JA, Shamie IS, Lakin PR, D'Cruz AA, Braun RO, Babon JJ, Lewis RS, Bliss-Moreau M, Shlomovitz I, Wang S, Cengia LH, Stoica AI, Hakem R, Kelliher MA, O'Reilly LA, Patsiouras H, Lawlor KE, Weller E, Lewis NE, Roberts AW, Gerlic M, Croker BA.

Nat Immunol. 2020 Jan;21(1):54-64. doi: 10.1038/s41590-019-0550-7. Epub 2019 Dec 9.

PMID:
31819256
2.

Deleting Suppressor of Cytokine Signaling-3 in chondrocytes reduces bone growth by disrupting mitogen-activated protein kinase signaling.

Liu X, D'Cruz AA, Hansen J, Croker BA, Lawlor KE, Sims NA, Wicks IP.

Osteoarthritis Cartilage. 2019 Oct;27(10):1557-1563. doi: 10.1016/j.joca.2019.05.018. Epub 2019 Jun 5.

PMID:
31176017
3.

The pseudokinase MLKL activates PAD4-dependent NET formation in necroptotic neutrophils.

D'Cruz AA, Speir M, Bliss-Moreau M, Dietrich S, Wang S, Chen AA, Gavillet M, Al-Obeidi A, Lawlor KE, Vince JE, Kelliher MA, Hakem R, Pasparakis M, Williams DA, Ericsson M, Croker BA.

Sci Signal. 2018 Sep 4;11(546). pii: eaao1716. doi: 10.1126/scisignal.aao1716.

4.

Identification of a second binding site on the TRIM25 B30.2 domain.

D'Cruz AA, Kershaw NJ, Hayman TJ, Linossi EM, Chiang JJ, Wang MK, Dagley LF, Kolesnik TB, Zhang JG, Masters SL, Griffin MDW, Gack MU, Murphy JM, Nicola NA, Babon JJ, Nicholson SE.

Biochem J. 2018 Jan 23;475(2):429-440. doi: 10.1042/BCJ20170427.

5.

Defining a therapeutic window for kinase inhibitors in leukemia to avoid neutropenia.

McArthur K, D'Cruz AA, Segal D, Lackovic K, Wilks AF, O'Donnell JA, Nowell CJ, Gerlic M, Huang DCS, Burns CJ, Croker BA.

Oncotarget. 2017 Jul 28;8(35):57948-57963. doi: 10.18632/oncotarget.19678. eCollection 2017 Aug 29.

6.

A motive for killing: effector functions of regulated lytic cell death.

Bliss-Moreau M, Chen AA, D'Cruz AA, Croker BA.

Immunol Cell Biol. 2017 Feb;95(2):146-151. doi: 10.1038/icb.2016.113. Epub 2016 Nov 9. Review.

7.

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL.

Lawlor KE, Khan N, Mildenhall A, Gerlic M, Croker BA, D'Cruz AA, Hall C, Kaur Spall S, Anderton H, Masters SL, Rashidi M, Wicks IP, Alexander WS, Mitsuuchi Y, Benetatos CA, Condon SM, Wong WW, Silke J, Vaux DL, Vince JE.

Nat Commun. 2015 Feb 18;6:6282. doi: 10.1038/ncomms7282.

8.

Crystal structure of the TRIM25 B30.2 (PRYSPRY) domain: a key component of antiviral signalling.

D'Cruz AA, Kershaw NJ, Chiang JJ, Wang MK, Nicola NA, Babon JJ, Gack MU, Nicholson SE.

Biochem J. 2013 Dec 1;456(2):231-40. doi: 10.1042/BJ20121425.

9.

Structure and function of the SPRY/B30.2 domain proteins involved in innate immunity.

D'Cruz AA, Babon JJ, Norton RS, Nicola NA, Nicholson SE.

Protein Sci. 2013 Jan;22(1):1-10. doi: 10.1002/pro.2185. Review.

10.

TLR regulation of SPSB1 controls inducible nitric oxide synthase induction.

Lewis RS, Kolesnik TB, Kuang Z, D'Cruz AA, Blewitt ME, Masters SL, Low A, Willson T, Norton RS, Nicholson SE.

J Immunol. 2011 Oct 1;187(7):3798-805. doi: 10.4049/jimmunol.1002993. Epub 2011 Aug 29.

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