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A phase Ib study of BGJ398, a pan-FGFR kinase inhibitor in combination with imatinib in patients with advanced gastrointestinal stromal tumor.

Kelly CM, Shoushtari AN, Qin LX, D'Angelo SP, Dickson MA, Gounder MM, Keohan ML, Mcfadyen C, Sjoberg A, Singer S, DeMatteo RP, Hwang S, Heinemann MH, Francis JH, Antonescu CR, Chi P, Tap WD.

Invest New Drugs. 2018 Aug 13. doi: 10.1007/s10637-018-0648-z. [Epub ahead of print]


COMMENTS ON "Short-term reasons for withdrawal and adverse events associated with apremilast therapy for psoriasis in real-world practice compared with in clinical trials: A multicenter retrospective study".

Favalli EG, Conti F, Atzeni F, Selmi C, D'Angelo S, Caporali R, Iannone F.

J Am Acad Dermatol. 2018 Aug 7. pii: S0190-9622(18)32359-4. doi: 10.1016/j.jaad.2018.07.052. [Epub ahead of print] No abstract available.


New Insights into Behçet's Syndrome Metabolic Reprogramming: Citrate Pathway Dysregulation.

Santarsiero A, Leccese P, Convertini P, Padula A, Abriola P, D'Angelo S, Bisaccia F, Infantino V.

Mediators Inflamm. 2018 Jun 28;2018:1419352. doi: 10.1155/2018/1419352. eCollection 2018.


Diffuse Idiopathic Skeletal Hyperostosis in an HLA-B27-Positive Subject.

Gilio M, Scarano E, Padula A, Tramontano G, DʼAngelo S, Olivieri I.

J Clin Rheumatol. 2018 Jul 25. doi: 10.1097/RHU.0000000000000865. [Epub ahead of print] No abstract available.


Comparison of lente insulin and NPH insulin therapy for the treatment of newly diagnosed diabetic dogs: a randomised study.

Fracassi F, Linari G, Del Baldo F, Di Cunzolo A, D'Angelo S, Malerba E, Carotenuto G, Bonfanti U, Corradini S.

Vet Rec. 2018 Jul 20. pii: vetrec-2017-104818. doi: 10.1136/vr.104818. [Epub ahead of print]


Standardization of red flags for referral to rheumatologists and ophthalmologists in patients with rheumatic diseases and ocular involvement: a consensus statement.

Olivieri I, Accorinti M, Abicca I, Bisceglia P, Cimino L, Latanza L, Leccese P, Lubrano E, Marchesoni A, Miserocchi E, Neri P, Salvarani C, Scarpa R, D'Angelo S; CORE Study Group.

Rheumatol Int. 2018 Jun 30. doi: 10.1007/s00296-018-4094-1. [Epub ahead of print]


Clinical Outcomes of Preloaded Descemet Membrane Endothelial Keratoplasty Grafts With Endothelium Tri-Folded Inwards.

Busin M, Leon P, D'Angelo S, Ruzza A, Ferrari S, Ponzin D, Parekh M.

Am J Ophthalmol. 2018 Jun 27;193:106-113. doi: 10.1016/j.ajo.2018.06.013. [Epub ahead of print]


Current treatment options for psoriatic arthritis: spotlight on abatacept.

Ursini F, Russo E, De Giorgio R, De Sarro G, D'Angelo S.

Ther Clin Risk Manag. 2018 Jun 6;14:1053-1059. doi: 10.2147/TCRM.S148586. eCollection 2018. Review.


Metformin and Autoimmunity: A "New Deal" of an Old Drug.

Ursini F, Russo E, Pellino G, D'Angelo S, Chiaravalloti A, De Sarro G, Manfredini R, De Giorgio R.

Front Immunol. 2018 Jun 4;9:1236. doi: 10.3389/fimmu.2018.01236. eCollection 2018. Review.


Physician's Global Assessment in Psoriatic Arthritis: A Multicenter GRAPPA Study.

Cauli A, Gladman DD, Mathieu A, Olivieri I, Porru G, Tak PP, Sardu C, Scarpa R, Marchesoni A, Taylor WJ, Salvarani C, Kalden J, Lubrano E, Carneiro S, Piga M, Floris A, Desiati F, Flynn JA, D'Angelo S, van Kuijk AWR, Catanoso MG, Caso F, Contu P, Ujfalussy I, Helliwell PS, Mease PJ; for the GRAPPA 3PPsA Study Group.

J Rheumatol. 2018 Jun 15. pii: jrheum.171183. doi: 10.3899/jrheum.171183. [Epub ahead of print]


Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1 c259T Cells in Synovial Sarcoma.

D'Angelo SP, Melchiori L, Merchant MS, Bernstein D, Glod J, Kaplan R, Grupp S, Tap WD, Chagin K, Binder GK, Basu S, Lowther DE, Wang R, Bath N, Tipping A, Betts G, Ramachandran I, Navenot JM, Zhang H, Wells DK, Van Winkle E, Kari G, Trivedi T, Holdich T, Pandite L, Amado R, Mackall CL.

Cancer Discov. 2018 Aug;8(8):944-957. doi: 10.1158/2159-8290.CD-17-1417. Epub 2018 Jun 11.


Rapid purification of billions of circulating CD19+ B cells directly from leukophoresis samples.

Ferrara F, Kolnik M, D'Angelo S, Erasmus FM, Vorholt D, Bradbury ARM.

N Biotechnol. 2018 Nov 25;46:14-21. doi: 10.1016/j.nbt.2018.05.006. Epub 2018 Jun 2.


Selection of phage-displayed accessible recombinant targeted antibodies (SPARTA): methodology and applications.

D'Angelo S, Staquicini FI, Ferrara F, Staquicini DI, Sharma G, Tarleton CA, Nguyen H, Naranjo LA, Sidman RL, Arap W, Bradbury AR, Pasqualini R.

JCI Insight. 2018 May 3;3(9). pii: 98305. doi: 10.1172/jci.insight.98305. [Epub ahead of print]


Dissecting the pathophysiology of immune thrombotic thrombocytopenic purpura: interplay between genes and environmental triggers.

Hrdinová J, D'Angelo S, Graça NAG, Ercig B, Vanhoorelbeke K, Veyradier A, Voorberg J, Coppo P.

Haematologica. 2018 Jul;103(7):1099-1109. doi: 10.3324/haematol.2016.151407. Epub 2018 Apr 19. Review.


ERAP1 molecular characterization: Identification of a de novo allelic variant.

Padula MC, Leccese P, Padula AA, D'Angelo S, Martelli G.

HLA. 2018 Mar 26. doi: 10.1111/tan.13262. [Epub ahead of print]


Many Routes to an Antibody Heavy-Chain CDR3: Necessary, Yet Insufficient, for Specific Binding.

D'Angelo S, Ferrara F, Naranjo L, Erasmus MF, Hraber P, Bradbury ARM.

Front Immunol. 2018 Mar 8;9:395. doi: 10.3389/fimmu.2018.00395. eCollection 2018.


Efficacy and Safety of First-line Avelumab Treatment in Patients With Stage IV Metastatic Merkel Cell Carcinoma: A Preplanned Interim Analysis of a Clinical Trial.

D'Angelo SP, Russell J, Lebbé C, Chmielowski B, Gambichler T, Grob JJ, Kiecker F, Rabinowits G, Terheyden P, Zwiener I, Bajars M, Hennessy M, Kaufman HL.

JAMA Oncol. 2018 Mar 22. doi: 10.1001/jamaoncol.2018.0077. [Epub ahead of print]


Multidisciplinary Management of Spondyloarthritis-Related Immune-Mediated Inflammatory Disease.

Rizzello F, Olivieri I, Armuzzi A, Ayala F, Bettoli V, Bianchi L, Cimino L, Costanzo A, Cristaudo A, D'Angelo S, Daperno M, Fostini AC, Galeazzi M, Gilio M, Gionchetti P, Gisondi P, Lubrano E, Marchesoni A, Offidani A, Orlando A, Pugliese D, Salvarani C, Scarpa R, Vecchi M, Girolomoni G.

Adv Ther. 2018 Apr;35(4):545-562. doi: 10.1007/s12325-018-0672-6. Epub 2018 Mar 7.


Is the recent increment in attributable deaths to type-2 diabetes (T2D) associated with the latest chikungunya outbreak in a major epidemic area in Brazil?

Cavalcanti LPG, D'angelo SM, Lemos DRQ, Barreto FKA, Siqueira AM, Miyajima F.

Rev Soc Bras Med Trop. 2018 Jan-Feb;51(1):63-65. doi: 10.1590/0037-8682-0440-2017.


Safety of treatment options for spondyloarthritis: a narrative review.

D'Angelo S, Carriero A, Gilio M, Ursini F, Leccese P, Palazzi C.

Expert Opin Drug Saf. 2018 May;17(5):475-486. doi: 10.1080/14740338.2018.1448785. Epub 2018 Mar 14. Review.


Prior fragility fracture and risk of incident ischaemic cardiovascular events: results from UK Biobank.

Paccou J, D'Angelo S, Rhodes A, Curtis EM, Raisi-Estabragh Z, Edwards M, Walker-Bone K, Cooper C, Petersen SE, Harvey NC.

Osteoporos Int. 2018 Jun;29(6):1321-1328. doi: 10.1007/s00198-018-4426-8. Epub 2018 Feb 26.


A step towards standardization: A method for end-point titer determination by fluorescence index of an automated microscope. End-point titer determination by fluorescence index.

Carbone T, Gilio M, Padula MC, Tramontano G, D'Angelo S, Pafundi V.

J Immunol Methods. 2018 May;456:67-71. doi: 10.1016/j.jim.2018.02.014. Epub 2018 Feb 19.


Primer Design and Inverse PCR on Yeast Display Antibody Selection Outputs.

Ferrara F, Bradbury ARM, D'Angelo S.

Methods Mol Biol. 2018;1721:35-45. doi: 10.1007/978-1-4939-7546-4_4.


The Sex Influence on Response to Tumor Necrosis Factor-α Inhibitors and Remission in Axial Spondyloarthritis.

Lubrano E, Perrotta FM, Manara M, D'Angelo S, Addimanda O, Ramonda R, Punzi L, Olivieri I, Salvarani C, Marchesoni A.

J Rheumatol. 2018 Feb;45(2):195-201. doi: 10.3899/jrheum.170666.


Nivolumab with or without ipilimumab treatment for metastatic sarcoma (Alliance A091401): two open-label, non-comparative, randomised, phase 2 trials.

D'Angelo SP, Mahoney MR, Van Tine BA, Atkins J, Milhem MM, Jahagirdar BN, Antonescu CR, Horvath E, Tap WD, Schwartz GK, Streicher H.

Lancet Oncol. 2018 Mar;19(3):416-426. doi: 10.1016/S1470-2045(18)30006-8. Epub 2018 Jan 19.


Updated efficacy of avelumab in patients with previously treated metastatic Merkel cell carcinoma after ≥1 year of follow-up: JAVELIN Merkel 200, a phase 2 clinical trial.

Kaufman HL, Russell JS, Hamid O, Bhatia S, Terheyden P, D'Angelo SP, Shih KC, Lebbé C, Milella M, Brownell I, Lewis KD, Lorch JH, von Heydebreck A, Hennessy M, Nghiem P.

J Immunother Cancer. 2018 Jan 19;6(1):7. doi: 10.1186/s40425-017-0310-x.


Calcium and Vitamin D Supplementation Are Not Associated With Risk of Incident Ischemic Cardiac Events or Death: Findings From the UK Biobank Cohort.

Harvey NC, D'Angelo S, Paccou J, Curtis EM, Edwards M, Raisi-Estabragh Z, Walker-Bone K, Petersen SE, Cooper C.

J Bone Miner Res. 2018 May;33(5):803-811. doi: 10.1002/jbmr.3375. Epub 2018 Feb 8.


Cytokine release syndrome after radiation therapy: case report and review of the literature.

Barker CA, Kim SK, Budhu S, Matsoukas K, Daniyan AF, D'Angelo SP.

J Immunother Cancer. 2018 Jan 3;6(1):1. doi: 10.1186/s40425-017-0311-9.


Langerhans-type dendritic cells electroporated with TRP-2 mRNA stimulate cellular immunity against melanoma: Results of a phase I vaccine trial.

Chung DJ, Carvajal RD, Postow MA, Sharma S, Pronschinske KB, Shyer JA, Singh-Kandah S, Dickson MA, D'Angelo SP, Wolchok JD, Young JW.

Oncoimmunology. 2017 Sep 21;7(1):e1372081. doi: 10.1080/2162402X.2017.1372081. eCollection 2017.


Effect of Saccharomyces boulardii in dog with chronic enteropathies: double-blinded, placebo-controlled study.

D'Angelo S, Fracassi F, Bresciani F, Galuppi R, Diana A, Linta N, Bettini G, Morini M, Pietra M.

Vet Rec. 2018 Mar 3;182(9):258. doi: 10.1136/vr.104241. Epub 2017 Dec 6.


Therapeutic targeting of membrane-associated GRP78 in leukemia and lymphoma: preclinical efficacy in vitro and formal toxicity study of BMTP-78 in rodents and primates.

Staquicini DI, D'Angelo S, Ferrara F, Karjalainen K, Sharma G, Smith TL, Tarleton CA, Jaalouk DE, Kuniyasu A, Baze WB, Chaffee BK, Hanley PW, Barnhart KF, Koivunen E, Marchiò S, Sidman RL, Cortes JE, Kantarjian HM, Arap W, Pasqualini R.

Pharmacogenomics J. 2018 May 22;18(3):436-443. doi: 10.1038/tpj.2017.46. Epub 2017 Dec 5.


Recommendations for the use of biologics and other novel drugs in the treatment of psoriatic arthritis: 2017 update from the Italian Society of Rheumatology.

Marchesoni A, Olivieri I, Salvarani C, Pipitone N, D'Angelo S, Mathieu A, Cauli A, Punzi L, Ramonda R, Scarpa R, Maccarone M, Lubrano E.

Clin Exp Rheumatol. 2017 Nov-Dec;35(6):991-1010. Epub 2017 Nov 28.


Pure red aplasia induced by sodium valproate in a patient with Behçet's syndrome.

Leccese P, Attolico I, Padula A, Diplomatico A, D'Angelo S, Olivieri I.

Clin Exp Rheumatol. 2017 Nov-Dec;35 Suppl 108(6):132. Epub 2017 Oct 27. No abstract available.


The Sex Influence on Response to Tumor Necrosis Factor-α Inhibitors and Remission in Axial Spondyloarthritis.

Lubrano E, Perrotta FM, Manara M, D'Angelo S, Addimanda O, Ramonda R, Punzi L, Olivieri I, Salvarani C, Marchesoni A.

J Rheumatol. 2017 Nov 15. pii: jrheum.17666. doi: 10.3899/jrheum.17666. [Epub ahead of print]


A phase 2 study of ontuxizumab, a monoclonal antibody targeting endosialin, in metastatic melanoma.

D'Angelo SP, Hamid OA, Tarhini A, Schadendorf D, Chmielowski B, Collichio FA, Pavlick AC, Lewis KD, Weil SC, Heyburn J, Schweizer C, O'Shannessy DJ, Carvajal RD.

Invest New Drugs. 2018 Feb;36(1):103-113. doi: 10.1007/s10637-017-0530-4. Epub 2017 Nov 11.


Is Repeat Pulmonary Metastasectomy Indicated for Soft Tissue Sarcoma?

Chudgar NP, Brennan MF, Tan KS, Munhoz RR, D'Angelo SP, Bains MS, Huang J, Park BJ, Adusumilli PS, Tap WD, Jones DR.

Ann Thorac Surg. 2017 Dec;104(6):1837-1845. doi: 10.1016/j.athoracsur.2017.07.024. Epub 2017 Nov 2.


Autoantibodies against the cell surface-associated chaperone GRP78 stimulate tumor growth via tissue factor.

Al-Hashimi AA, Lebeau P, Majeed F, Polena E, Lhotak Š, Collins CAF, Pinthus JH, Gonzalez-Gronow M, Hoogenes J, Pizzo SV, Crowther M, Kapoor A, Rak J, Gyulay G, D'Angelo S, Marchiò S, Pasqualini R, Arap W, Shayegan B, Austin RC.

J Biol Chem. 2017 Dec 22;292(51):21180-21192. doi: 10.1074/jbc.M117.799908. Epub 2017 Oct 24.


Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial.

Tawbi HA, Burgess M, Bolejack V, Van Tine BA, Schuetze SM, Hu J, D'Angelo S, Attia S, Riedel RF, Priebat DA, Movva S, Davis LE, Okuno SH, Reed DR, Crowley J, Butterfield LH, Salazar R, Rodriguez-Canales J, Lazar AJ, Wistuba II, Baker LH, Maki RG, Reinke D, Patel S.

Lancet Oncol. 2017 Nov;18(11):1493-1501. doi: 10.1016/S1470-2045(17)30624-1. Epub 2017 Oct 4. Erratum in: Lancet Oncol. 2017 Dec;18(12 ):e711. Lancet Oncol. 2018 Jan;19(1):e8.


Complement C3 and fatty liver disease in Rheumatoid arthritis patients: a cross-sectional study.

Ursini F, Russo E, Mauro D, Abenavoli L, Ammerata G, Serrao A, Grembiale RD, De Sarro G, Olivieri I, D'angelo S.

Eur J Clin Invest. 2017 Oct;47(10):728-735. doi: 10.1111/eci.12798. Epub 2017 Sep 2.


Pro-oxidant and pro-apoptotic activity of polyphenol extract from Annurca apple and its underlying mechanisms in human breast cancer cells.

D'Angelo S, Martino E, Ilisso CP, Bagarolo ML, Porcelli M, Cacciapuoti G.

Int J Oncol. 2017 Sep;51(3):939-948. doi: 10.3892/ijo.2017.4088. Epub 2017 Jul 31.


Anti-TNF-alpha agents and endothelial function in rheumatoid arthritis: a systematic review and meta-analysis.

Ursini F, Leporini C, Bene F, D'Angelo S, Mauro D, Russo E, De Sarro G, Olivieri I, Pitzalis C, Lewis M, Grembiale RD.

Sci Rep. 2017 Jul 13;7(1):5346. doi: 10.1038/s41598-017-05759-2.


Overall Survival in Patients With Advanced Melanoma Who Received Nivolumab Versus Investigator's Choice Chemotherapy in CheckMate 037: A Randomized, Controlled, Open-Label Phase III Trial.

Larkin J, Minor D, D'Angelo S, Neyns B, Smylie M, Miller WH Jr, Gutzmer R, Linette G, Chmielowski B, Lao CD, Lorigan P, Grossmann K, Hassel JC, Sznol M, Daud A, Sosman J, Khushalani N, Schadendorf D, Hoeller C, Walker D, Kong G, Horak C, Weber J.

J Clin Oncol. 2018 Feb 1;36(4):383-390. doi: 10.1200/JCO.2016.71.8023. Epub 2017 Jul 3.


Vitamin D deficiency in systemic sclerosis: a possible role of subclinical liver fibrosis? Retrospective analysis from an Italian cohort.

Ursini F, D'Angelo S, Padula A, Leccese P, Abignano G, Mennillo GA, Ammerata G, De Sarro G, Olivieri I.

Clin Rheumatol. 2017 Dec;36(12):2871-2872. doi: 10.1007/s10067-017-3709-3. Epub 2017 Jun 3. No abstract available.


Response to Antenatal Cholecalciferol Supplementation Is Associated With Common Vitamin D-Related Genetic Variants.

Moon RJ, Harvey NC, Cooper C, D'Angelo S, Curtis EM, Crozier SR, Barton SJ, Robinson SM, Godfrey KM, Graham NJ, Holloway JW, Bishop NJ, Kennedy S, Papageorghiou AT, Schoenmakers I, Fraser R, Gandhi SV, Prentice A, Inskip HM, Javaid MK; Maternal Vitamin D Osteoporosis Study Trial Group.

J Clin Endocrinol Metab. 2017 Aug 1;102(8):2941-2949. doi: 10.1210/jc.2017-00682.


Role of positron emission tomography for central nervous system involvement in systemic autoimmune diseases: status and perspectives.

Mauro D, Barbagallo G, D'Angelo S, Pasqualina S, Naty S, Bruno C, Olivieri I, Grembiale RD, Ursini F.

Curr Med Chem. 2017 May 23. doi: 10.2174/0929867324666170523144402. [Epub ahead of print]


Pulmonary metastasectomy with therapeutic intent for soft-tissue sarcoma.

Chudgar NP, Brennan MF, Munhoz RR, Bucciarelli PR, Tan KS, D'Angelo SP, Bains MS, Bott M, Huang J, Park BJ, Rusch VW, Adusumilli PS, Tap WD, Singer S, Jones DR.

J Thorac Cardiovasc Surg. 2017 Jul;154(1):319-330.e1. doi: 10.1016/j.jtcvs.2017.02.061. Epub 2017 Mar 21.


Plantar fascia enthesopathy is highly prevalent in diabetic patients without peripheral neuropathy and correlates with retinopathy and impaired kidney function.

Ursini F, Arturi F, Nicolosi K, Ammendolia A, D'Angelo S, Russo E, Naty S, Bruno C, De Sarro G, Olivieri I, Grembiale RD.

PLoS One. 2017 Mar 30;12(3):e0174529. doi: 10.1371/journal.pone.0174529. eCollection 2017.


Getting started with tables.

Inskip H, Ntani G, Westbury L, Di Gravio C, D'Angelo S, Parsons C, Baird J.

Arch Public Health. 2017 Mar 20;75:14. doi: 10.1186/s13690-017-0180-1. eCollection 2017.


Using a modified Delphi process to establish clinical consensus for the diagnosis, risk assessment and abatacept treatment in patients with aggressive rheumatoid arthritis.

Caporali R, Carletto A, Conti F, D'Angelo S, Foti R, Gremese E, Govoni M, Iannone F, Pellerito R, Sinigaglia L.

Clin Exp Rheumatol. 2017 Sep-Oct;35(5):772-776. Epub 2017 Mar 3.


Review of the treatment of psoriatic arthritis with biological agents: choice of drug for initial therapy and switch therapy for non-responders.

D'Angelo S, Tramontano G, Gilio M, Leccese P, Olivieri I.

Open Access Rheumatol. 2017 Mar 2;9:21-28. doi: 10.2147/OARRR.S56073. eCollection 2017. Review.

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