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Items: 1 to 50 of 831

1.

Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II.

Jones CL, Stevens BM, D'Alessandro A, Culp-Hill R, Reisz JA, Pei S, Gustafson A, Khan N, DeGregori J, Pollyea DA, Jordan CT.

Blood. 2019 May 17. pii: blood.2019898114. doi: 10.1182/blood.2019898114. [Epub ahead of print]

PMID:
31101624
2.

Clickable Methyltetrazine-Indocarbocyanine Lipids: A Multicolor Tool Kit for Efficient Modifications of Cell Membranes.

Gaikwad H, Wang G, Smith WJ, Alexander KL, D'Alessandro A, Zhang W, Purev E, Simberg D.

Bioconjug Chem. 2019 May 3. doi: 10.1021/acs.bioconjchem.9b00202. [Epub ahead of print]

PMID:
31050882
3.

The TP53 Apoptotic Network is a Primary Mediator of Resistance to BCL2 inhibition in AML Cells.

Nechiporuk T, Kurtz SE, Nikolova O, Liu T, Jones CL, D'Alessandro A, Culp-Hill R, d'Almeida A, Joshi SK, Rosenberg M, Tognon CE, Danilov AV, Druker BJ, Chang BH, McWeeney SK, Tyner JW.

Cancer Discov. 2019 May 2. pii: CD-19-0125. doi: 10.1158/2159-8290.CD-19-0125. [Epub ahead of print]

PMID:
31048320
4.

Mass spectrometry-based molecular mapping of native FXIIIa cross-links in insoluble fibrin clots.

Schmitt LR, Henderson R, Barrett A, Darula Z, Issaian A, D'Alessandro A, Clendenen N, Hansen KC.

J Biol Chem. 2019 Apr 26. pii: jbc.AC119.007981. doi: 10.1074/jbc.AC119.007981. [Epub ahead of print]

5.

Reexamination of the chromium-51-labeled posttransfusion red blood cell recovery method.

Francis RO, Mahajan S, Rapido F, La Carpia F, Soffing M, Divgi C, Yeh R, Mintz A, Leslie L, Agrest I, Karafin MS, Ginzburg Y, Shaz BH, Spitalnik SL, Schwartz J, Thomas T, Fu X, Amireault P, Buffet P, Zimring JC, D'Alessandro A, Hod EA.

Transfusion. 2019 Apr 19. doi: 10.1111/trf.15310. [Epub ahead of print]

PMID:
31002399
6.

Brain Death Enhances Activation of the Innate Immune System and Leads to Reduced Renal Metabolic Gene Expression.

Zitur LJ, Chlebeck PJ, Odorico SK, Danobeitia JS, Zens TJ, Van Kooten C, Eerhart M, Reyes JA, Springer ML, Coonen JM, Brunner KG, Capuano SV, D'Alessandro AM, Fernandez LA.

Transplantation. 2019 Apr 4. doi: 10.1097/TP.0000000000002744. [Epub ahead of print]

PMID:
30964836
7.

The Hematopoietic Oxidase NOX2 Regulates Self-Renewal of Leukemic Stem Cells.

Adane B, Ye H, Khan N, Pei S, Minhajuddin M, Stevens BM, Jones CL, D'Alessandro A, Reisz JA, Zaberezhnyy V, Gasparetto M, Ho TC, Kelly KK, Myers JR, Ashton JM, Siegenthaler J, Kume T, Campbell EL, Pollyea DA, Becker MW, Jordan CT.

Cell Rep. 2019 Apr 2;27(1):238-254.e6. doi: 10.1016/j.celrep.2019.03.009.

8.

Targeting Glutamine Metabolism and Redox State for Leukemia Therapy.

Gregory MA, Nemkov T, Park HJ, Zaberezhnyy V, Gehrke S, Adane B, Jordan CT, Hansen KC, D'Alessandro A, DeGregori J.

Clin Cancer Res. 2019 Apr 2. doi: 10.1158/1078-0432.CCR-18-3223. [Epub ahead of print]

PMID:
30940653
9.

Could the Less-Than Subtotal Parathyroidectomy Be an Option for Treating Young Patients With Multiple Endocrine Neoplasia Type 1-Related Hyperparathyroidism?

Montenegro FLM, Brescia MDG, Lourenço DM Jr, Arap SS, d'Alessandro AF, de Britto E Silva Filho G, Toledo SPA.

Front Endocrinol (Lausanne). 2019 Mar 7;10:123. doi: 10.3389/fendo.2019.00123. eCollection 2019.

10.

Effects of aged stored autologous red blood cells on human plasma metabolome.

D'Alessandro A, Reisz JA, Zhang Y, Gehrke S, Alexander K, Kanias T, Triulzi DJ, Donadee C, Barge S, Badlam J, Jain S, Risbano MG, Gladwin MT.

Blood Adv. 2019 Mar 26;3(6):884-896. doi: 10.1182/bloodadvances.2018029629.

11.

Higher Gestational Choline Levels in Maternal Infection Are Protective for Infant Brain Development.

Freedman R, Hunter SK, Law AJ, Wagner BD, D'Alessandro A, Christians U, Noonan K, Wyrwa A, Hoffman MC.

J Pediatr. 2019 May;208:198-206.e2. doi: 10.1016/j.jpeds.2018.12.010. Epub 2019 Mar 14.

PMID:
30879727
12.

Chronological storage age and metabolic age of stored red blood cells: are they the same?

D'Alessandro A, Zimring JC, Busch M.

Transfusion. 2019 May;59(5):1620-1623. doi: 10.1111/trf.15248. Epub 2019 Mar 13. Review.

PMID:
30865302
13.

Improved clinical outcome following liver transplant in patients with ethylmalonic encephalopathy.

Tam A, AlDhaheri NS, Mysore K, Tessier ME, Goss J, Fernandez LA, D'Alessandro AM, Schwoerer JS, Rice GM, Elsea SH, Scaglia F.

Am J Med Genet A. 2019 Jun;179(6):1015-1019. doi: 10.1002/ajmg.a.61104. Epub 2019 Mar 12.

PMID:
30864297
14.

Correction to: Massive Gastrointestinal Bleeding Due to Splenic Artery Erosion by a PigTail Drain in a Post Sleeve Gastrectomy Leak: a Case Report.

Chahine E, D'Alessandro A, Elhajjam M, Moryoussef F, Vitte RL, Carlier R, Alsabah S, Chouillard E.

Obes Surg. 2019 May;29(5):1657. doi: 10.1007/s11695-019-03787-7.

PMID:
30830532
15.

Quantitative metabolomics comparison of traditional blood draws and TAP capillary blood collection.

Catala A, Culp-Hill R, Nemkov T, D'Alessandro A.

Metabolomics. 2018 Jul 12;14(7):100. doi: 10.1007/s11306-018-1395-z.

PMID:
30830393
16.

Urea Cycle Sustains Cellular Energetics upon EGFR Inhibition in EGFR-Mutant NSCLC.

Pham-Danis C, Gehrke S, Danis E, Rozhok AI, Daniels MW, Gao D, Collins C, Paola JTD, D'Alessandro A, DeGregori J.

Mol Cancer Res. 2019 Feb 26. doi: 10.1158/1541-7786.MCR-18-1068. [Epub ahead of print]

PMID:
30808730
17.

Red Blood Cell Metabolic Responses to Torpor and Arousal in the Hibernator Arctic Ground Squirrel.

Gehrke S, Rice S, Stefanoni D, Wilkerson RB, Nemkov T, Reisz JA, Hansen KC, Lucas A, Cabrales P, Drew K, D'Alessandro A.

J Proteome Res. 2019 Apr 5;18(4):1827-1841. doi: 10.1021/acs.jproteome.9b00018. Epub 2019 Feb 28.

PMID:
30793910
18.

SIRT1 participates in the response to methylglyoxal-dependent glycative stress in mouse oocytes and ovary.

Di Emidio G, Santini SJ, D'Alessandro AM, Vetuschi A, Sferra R, Artini PG, Carta G, Falone S, Amicarelli F, Tatone C.

Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1389-1401. doi: 10.1016/j.bbadis.2019.02.011. Epub 2019 Feb 13.

PMID:
30771486
19.

Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells.

Jones CL, Stevens BM, D'Alessandro A, Reisz JA, Culp-Hill R, Nemkov T, Pei S, Khan N, Adane B, Ye H, Krug A, Reinhold D, Smith C, DeGregori J, Pollyea DA, Jordan CT.

Cancer Cell. 2019 Feb 11;35(2):333-335. doi: 10.1016/j.ccell.2019.01.013. No abstract available.

20.

Increase in post-reperfusion sensitivity to tissue plasminogen activator-mediated fibrinolysis during liver transplantation is associated with abnormal metabolic changes and increased blood product utilisation.

Moore HB, D'alessandro A, Moore EE, Wither M, Lawson PJ, Huebner BR, Hansen K, Choudhury R, Nydam TL.

Blood Transfus. 2019 Feb 4:1-9. doi: 10.2450/2019.0205-18. [Epub ahead of print]

21.

Selective organ ischaemia/reperfusion identifies liver as the key driver of the post-injury plasma metabolome derangements.

Clendenen N, Nunns GR, Moore EE, Gonzalez E, Chapman M, Reisz JA, Peltz E, Fragoso M, Nemkov T, Wither MJ, Sauaia A, Silliman CC, Hansen K, Banerjee A, D'alessandro A, Moore HB.

Blood Transfus. 2018 Dec 13:1-13. doi: 10.2450/2018.0188-18. [Epub ahead of print]

22.

Massive Gastrointestinal Bleeding Due to Splenic Artery Erosion by a PigTail Drain in a Post Sleeve Gastrectomy Leak: a Case Report.

Chahine E, D'Alessandro A, Elhajjam M, Moryoussef F, Vitte RL, Carlier R, Alsabah S, Chouillard E.

Obes Surg. 2019 May;29(5):1653-1656. doi: 10.1007/s11695-019-03765-z. No abstract available. Erratum in: Obes Surg. 2019 Mar 4;:.

PMID:
30747387
23.

Metabolomics assessment reveals oxidative stress and altered energy production in the heart after ischemic acute kidney injury in mice.

Fox BM, Gil HW, Kirkbride-Romeo L, Bagchi RA, Wennersten SA, Haefner KR, Skrypnyk NI, Brown CN, Soranno DE, Gist KM, Griffin BR, Jovanovich A, Reisz JA, Wither MJ, D'Alessandro A, Edelstein CL, Clendenen N, McKinsey TA, Altmann C, Faubel S.

Kidney Int. 2019 Mar;95(3):590-610. doi: 10.1016/j.kint.2018.10.020. Epub 2019 Jan 30.

PMID:
30709662
24.

High Throughput Metabolomics in Clinical Studies: Review and New Applications to Remote Ischemic Preconditioning.

Clendenen N, D'Alessandro A.

Curr Top Med Chem. 2018;18(25):2143-2153. doi: 10.2174/1568026619666181130140937. Review.

PMID:
30698107
25.

From omics technologies to personalized transfusion medicine.

D'Alessandro A.

Expert Rev Proteomics. 2019 Mar;16(3):215-225. doi: 10.1080/14789450.2019.1571917. Epub 2019 Jan 28.

PMID:
30654673
26.

Red blood cell storage lesion: causes and potential clinical consequences.

Yoshida T, Prudent M, D'alessandro A.

Blood Transfus. 2019 Jan;17(1):27-52. doi: 10.2450/2019.0217-18. Review.

27.

Crystal structure of E. coli PRPP synthetase.

Zhou W, Tsai A, Dattmore DA, Stives DP, Chitrakar I, D'alessandro AM, Patil S, Hicks KA, French JB.

BMC Struct Biol. 2019 Jan 15;19(1):1. doi: 10.1186/s12900-019-0100-4.

28.

Crocetin and crocin from saffron in cancer chemotherapy and chemoprevention.

Festuccia C, Colapietro A, Mancini A, D'alessandro A.

Anticancer Agents Med Chem. 2018 Dec 30. doi: 10.2174/1871520619666181231112453. [Epub ahead of print]

PMID:
30599111
29.

p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression.

Moon SH, Huang CH, Houlihan SL, Regunath K, Freed-Pastor WA, Morris JP 4th, Tschaharganeh DF, Kastenhuber ER, Barsotti AM, Culp-Hill R, Xue W, Ho YJ, Baslan T, Li X, Mayle A, de Stanchina E, Zender L, Tong DR, D'Alessandro A, Lowe SW, Prives C.

Cell. 2019 Jan 24;176(3):564-580.e19. doi: 10.1016/j.cell.2018.11.011. Epub 2018 Dec 20.

30.

Urinary Metabolic Signature of Primary Aldosteronism: Gender and Subtype-Specific Alterations.

Lana A, Alexander K, Castagna A, D'Alessandro A, Morandini F, Pizzolo F, Zorzi F, Mulatero P, Zolla L, Olivieri O.

Proteomics Clin Appl. 2018 Dec 23:e1800049. doi: 10.1002/prca.201800049. [Epub ahead of print]

PMID:
30580498
31.

Red blood cell phenotype fidelity following glycerol cryopreservation optimized for research purposes.

Rogers SC, Dosier LB, McMahon TJ, Zhu H, Timm D, Zhang H, Herbert J, Atallah J, Palmer GM, Cook A, Ernst M, Prakash J, Terng M, Towfighi P, Doctor R, Said A, Joens MS, Fitzpatrick JAJ, Hanna G, Lin X, Reisz JA, Nemkov T, D'Alessandro A, Doctor A.

PLoS One. 2018 Dec 21;13(12):e0209201. doi: 10.1371/journal.pone.0209201. eCollection 2018.

32.

Dietary effect of lemon verbena extract on selected blood parameters and on plasma oxidative profile in Avelignese horses.

Palazzo M, Vizzarri F, Cinone M, D'Alessandro AG, Martemucci G, Casamassima D.

Anim Sci J. 2019 Feb;90(2):222-228. doi: 10.1111/asj.13057. Epub 2018 Dec 16.

PMID:
30556324
33.

Macrovascular venous invasion of pancreatic neuroendocrine tumours: impact on surgical outcomes and survival.

Addeo P, d'Alessandro A, Averous G, Imperiale A, Faitot F, Goichot B, Bachellier P.

HPB (Oxford). 2018 Dec 3. pii: S1365-182X(18)34507-6. doi: 10.1016/j.hpb.2018.10.010. [Epub ahead of print]

PMID:
30522946
34.

Widespread Backtracking by RNA Pol II Is a Major Effector of Gene Activation, 5' Pause Release, Termination, and Transcription Elongation Rate.

Sheridan RM, Fong N, D'Alessandro A, Bentley DL.

Mol Cell. 2019 Jan 3;73(1):107-118.e4. doi: 10.1016/j.molcel.2018.10.031. Epub 2018 Nov 29.

PMID:
30503775
35.

Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells.

Jones CL, Stevens BM, D'Alessandro A, Reisz JA, Culp-Hill R, Nemkov T, Pei S, Khan N, Adane B, Ye H, Krug A, Reinhold D, Smith C, DeGregori J, Pollyea DA, Jordan CT.

Cancer Cell. 2018 Nov 12;34(5):724-740.e4. doi: 10.1016/j.ccell.2018.10.005. Erratum in: Cancer Cell. 2019 Feb 11;35(2):333-335.

PMID:
30423294
36.

Venetoclax with azacitidine disrupts energy metabolism and targets leukemia stem cells in patients with acute myeloid leukemia.

Pollyea DA, Stevens BM, Jones CL, Winters A, Pei S, Minhajuddin M, D'Alessandro A, Culp-Hill R, Riemondy KA, Gillen AE, Hesselberth JR, Abbott D, Schatz D, Gutman JA, Purev E, Smith C, Jordan CT.

Nat Med. 2018 Dec;24(12):1859-1866. doi: 10.1038/s41591-018-0233-1. Epub 2018 Nov 12.

PMID:
30420752
37.

Influence of Mediterranean Diet on Blood Pressure.

De Pergola G, D'Alessandro A.

Nutrients. 2018 Nov 7;10(11). pii: E1700. doi: 10.3390/nu10111700. Review.

38.

The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD.

Soderborg TK, Clark SE, Mulligan CE, Janssen RC, Babcock L, Ir D, Lemas DJ, Johnson LK, Weir T, Lenz LL, Frank DN, Hernandez TL, Kuhn KA, D'Alessandro A, Barbour LA, El Kasmi KC, Friedman JE.

Nat Commun. 2018 Oct 26;9(1):4462. doi: 10.1038/s41467-018-06929-0.

39.

Heterogeneity of blood processing and storage additives in different centers impacts stored red blood cell metabolism as much as storage time: lessons from REDS-III-Omics.

D'Alessandro A, Culp-Hill R, Reisz JA, Anderson M, Fu X, Nemkov T, Gehrke S, Zheng C, Kanias T, Guo Y, Page G, Gladwin MT, Kleinman S, Lanteri M, Stone M, Busch M, Zimring JC; Recipient Epidemiology and Donor Evaluation Study-III (REDS-III).

Transfusion. 2019 Jan;59(1):89-100. doi: 10.1111/trf.14979. Epub 2018 Oct 24.

PMID:
30353560
40.

Switching obese mothers to a healthy diet improves fetal hypoxemia, hepatic metabolites, and lipotoxicity in non-human primates.

Wesolowski SR, Mulligan CM, Janssen RC, Baker PR 2nd, Bergman BC, D'Alessandro A, Nemkov T, Maclean KN, Jiang H, Dean TA, Takahashi DL, Kievit P, McCurdy CE, Aagaard KM, Friedman JE.

Mol Metab. 2018 Dec;18:25-41. doi: 10.1016/j.molmet.2018.09.008. Epub 2018 Sep 28.

41.

Methylation of protein aspartates and deamidated asparagines as a function of blood bank storage and oxidative stress in human red blood cells.

Reisz JA, Nemkov T, Dzieciatkowska M, Culp-Hill R, Stefanoni D, Hill RC, Yoshida T, Dunham A, Kanias T, Dumont LJ, Busch M, Eisenmesser EZ, Zimring JC, Hansen KC, D'Alessandro A.

Transfusion. 2018 Dec;58(12):2978-2991. doi: 10.1111/trf.14936. Epub 2018 Oct 12.

PMID:
30312994
42.

Red blood cells as an organ? How deep omics characterization of the most abundant cell in the human body highlights other systemic metabolic functions beyond oxygen transport.

Nemkov T, Reisz JA, Xia Y, Zimring JC, D'Alessandro A.

Expert Rev Proteomics. 2018 Nov;15(11):855-864. doi: 10.1080/14789450.2018.1531710. Epub 2018 Oct 14.

PMID:
30278801
43.

Effects of red blood cell (RBC) transfusion on sickle cell disease recipient plasma and RBC metabolism.

Culp-Hill R, Srinivasan AJ, Gehrke S, Kamyszek R, Ansari A, Shah N, Welsby I, D'Alessandro A.

Transfusion. 2018 Dec;58(12):2797-2806. doi: 10.1111/trf.14931. Epub 2018 Sep 28.

PMID:
30265764
44.

The clinical impact of glucose-6-phosphate dehydrogenase deficiency in patients with sickle cell disease.

Karafin MS, Fu X, D'Alessandro A, Thomas T, Hod EA, Zimring JC, Field JJ, Francis RO.

Curr Opin Hematol. 2018 Nov;25(6):494-499. doi: 10.1097/MOH.0000000000000455.

PMID:
30239377
45.

Reversal of Triple-Negative Breast Cancer EMT by miR-200c Decreases Tryptophan Catabolism and a Program of Immunosuppression.

Rogers TJ, Christenson JL, Greene LI, O'Neill KI, Williams MM, Gordon MA, Nemkov T, D'Alessandro A, Degala GD, Shin J, Tan AC, Cittelly DM, Lambert JR, Richer JK.

Mol Cancer Res. 2019 Jan;17(1):30-41. doi: 10.1158/1541-7786.MCR-18-0246. Epub 2018 Sep 13.

PMID:
30213797
46.

Characterization and targeting of malignant stem cells in patients with advanced myelodysplastic syndromes.

Stevens BM, Khan N, D'Alessandro A, Nemkov T, Winters A, Jones CL, Zhang W, Pollyea DA, Jordan CT.

Nat Commun. 2018 Sep 12;9(1):3694. doi: 10.1038/s41467-018-05984-x.

47.

Clonal expansion of vaccine-elicited T cells is independent of aerobic glycolysis.

Klarquist J, Chitrakar A, Pennock ND, Kilgore AM, Blain T, Zheng C, Danhorn T, Walton K, Jiang L, Sun J, Hunter CA, D'Alessandro A, Kedl RM.

Sci Immunol. 2018 Sep 7;3(27). pii: eaas9822. doi: 10.1126/sciimmunol.aas9822.

48.

A Role for Tryptophan-2,3-dioxygenase in CD8 T-cell Suppression and Evidence of Tryptophan Catabolism in Breast Cancer Patient Plasma.

Greene LI, Bruno TC, Christenson JL, D'Alessandro A, Culp-Hill R, Torkko K, Borges VF, Slansky JE, Richer JK.

Mol Cancer Res. 2019 Jan;17(1):131-139. doi: 10.1158/1541-7786.MCR-18-0362. Epub 2018 Aug 24.

PMID:
30143553
49.

KLF5 controls glutathione metabolism to suppress p190-BCR-ABL+ B-cell lymphoblastic leukemia.

Zhang C, D'Alessandro A, Wellendorf AM, Mohmoud F, Serrano-Lopez J, Perentesis JP, Komurov K, Alexe G, Stegmaier K, Whitsett JA, Grimes HL, Cancelas JA.

Oncotarget. 2018 Jul 3;9(51):29665-29679. doi: 10.18632/oncotarget.25667. eCollection 2018 Jul 3.

50.

Mitochondrial redox sensing by the kinase ATM maintains cellular antioxidant capacity.

Zhang Y, Lee JH, Paull TT, Gehrke S, D'Alessandro A, Dou Q, Gladyshev VN, Schroeder EA, Steyl SK, Christian BE, Shadel GS.

Sci Signal. 2018 Jul 10;11(538). pii: eaaq0702. doi: 10.1126/scisignal.aaq0702.

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