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Items: 42

1.

Determination of free desmosine in human plasma and its application in two experimental medicine studies.

Lamerz J, Friedlein A, Soder N, Cutler P, Döbeli H.

Anal Biochem. 2013 May 15;436(2):127-36. doi: 10.1016/j.ab.2013.01.012. Epub 2013 Feb 8.

PMID:
23399390
2.

Bace2 is a β cell-enriched protease that regulates pancreatic β cell function and mass.

Esterházy D, Stützer I, Wang H, Rechsteiner MP, Beauchamp J, Döbeli H, Hilpert H, Matile H, Prummer M, Schmidt A, Lieske N, Boehm B, Marselli L, Bosco D, Kerr-Conte J, Aebersold R, Spinas GA, Moch H, Migliorini C, Stoffel M.

Cell Metab. 2011 Sep 7;14(3):365-77. doi: 10.1016/j.cmet.2011.06.018.

3.

Use of the immunodominant 18-kiloDalton small heat shock protein as a serological marker for exposure to Mycobacterium ulcerans.

Diaz D, Döbeli H, Yeboah-Manu D, Mensah-Quainoo E, Friedlein A, Soder N, Rondini S, Bodmer T, Pluschke G.

Clin Vaccine Immunol. 2006 Dec;13(12):1314-21. Epub 2006 Oct 4.

4.

High sensitivity analysis of amyloid-beta peptide composition in amyloid deposits from human and PS2APP mouse brain.

Güntert A, Döbeli H, Bohrmann B.

Neuroscience. 2006 Dec 1;143(2):461-75. Epub 2006 Sep 27.

PMID:
17008022
5.

3D structure of Alzheimer's amyloid-beta(1-42) fibrils.

Lührs T, Ritter C, Adrian M, Riek-Loher D, Bohrmann B, Döbeli H, Schubert D, Riek R.

Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17342-7. Epub 2005 Nov 17.

6.

Protection of rat primary hippocampal cultures from A beta cytotoxicity by pro-inflammatory molecules is mediated by astrocytes.

Ramírez G, Toro R, Döbeli H, von Bernhardi R.

Neurobiol Dis. 2005 Jun-Jul;19(1-2):243-54.

PMID:
15837580
7.

Quantification of the A beta peptide in Alzheimer's plaques by laser dissection microscopy combined with mass spectrometry.

Rüfenacht P, Güntert A, Bohrmann B, Ducret A, Döbeli H.

J Mass Spectrom. 2005 Feb;40(2):193-201.

PMID:
15706631
8.

Substrate and inhibitor profile of BACE (beta-secretase) and comparison with other mammalian aspartic proteases.

Grüninger-Leitch F, Schlatter D, Küng E, Nelböck P, Döbeli H.

J Biol Chem. 2002 Feb 15;277(7):4687-93. Epub 2001 Dec 7.

10.

Immobilized amyloid precursor protein constructs: a tool for the in vitro screening of glial cell reactivity.

von Bernhardi R, Ramírez G, Matile H, Döbeli H.

Eur J Neurosci. 2001 Sep;14(6):946-56.

PMID:
11595033
11.

Self-assembly of beta-amyloid 42 is retarded by small molecular ligands at the stage of structural intermediates.

Bohrmann B, Adrian M, Dubochet J, Kuner P, Müller F, Huber W, Nordstedt C, Döbeli H.

J Struct Biol. 2000 Jun;130(2-3):232-46.

PMID:
10940228
12.

Identification of beta-secretase-like activity using a mass spectrometry-based assay system.

Grüninger-Leitch F, Berndt P, Langen H, Nelboeck P, Döbeli H.

Nat Biotechnol. 2000 Jan;18(1):66-70.

PMID:
10625394
13.

Endogenous proteins controlling amyloid beta-peptide polymerization. Possible implications for beta-amyloid formation in the central nervous system and in peripheral tissues.

Bohrmann B, Tjernberg L, Kuner P, Poli S, Levet-Trafit B, Näslund J, Richards G, Huber W, Döbeli H, Nordstedt C.

J Biol Chem. 1999 Jun 4;274(23):15990-5.

14.

Recombinant fusion proteins for the industrial production of disulfide bridge containing peptides: purification, oxidation without concatamer formation, and selective cleavage.

Döbeli H, Andres H, Breyer N, Draeger N, Sizmann D, Zuber MT, Weinert B, Wipf B.

Protein Expr Purif. 1998 Apr;12(3):404-14.

PMID:
9535709
15.

Crystal structure of fructose-1,6-bisphosphate aldolase from the human malaria parasite Plasmodium falciparum.

Kim H, Certa U, Döbeli H, Jakob P, Hol WG.

Biochemistry. 1998 Mar 31;37(13):4388-96.

PMID:
9521758
16.

The toxicity of the Alzheimer's beta-amyloid peptide correlates with a distinct fiber morphology.

Seilheimer B, Bohrmann B, Bondolfi L, Müller F, Stüber D, Döbeli H.

J Struct Biol. 1997 Jun;119(1):59-71.

PMID:
9216088
17.

Rapid drug screening for Alzheimer's.

Döbeli H.

Nat Biotechnol. 1997 Mar;15(3):223-4. No abstract available.

PMID:
9062918
18.

Recombinant human renin produced in different expression systems: biochemical properties and 3D structure.

Mathews S, Döbeli H, Pruschy M, Bosser R, D'Arcy A, Oefner C, Zulauf M, Gentz R, Breu V, Matile H, Schlaeger J, Fischli W.

Protein Expr Purif. 1996 Feb;7(1):81-91.

PMID:
9172787
19.

Crystallization of the complex of human IFN-gamma and the extracellular domain of the IFN-gamma receptor.

Chène C, Fountoulakis M, Döbeli H, D'Arcy B, Winkler F, D'Arcy A.

Proteins. 1995 Dec;23(4):591-4.

PMID:
8749856
20.

A biotechnological method provides access to aggregation competent monomeric Alzheimer's 1-42 residue amyloid peptide.

Döbeli H, Draeger N, Huber G, Jakob P, Schmidt D, Seilheimer B, Stüber D, Wipf B, Zulauf M.

Biotechnology (N Y). 1995 Sep;13(9):988-93. Erratum in: Biotechnology 1995 Nov;13(11):1142.

PMID:
9636276
21.

6xHis-Ni-NTA chromatography as a superior technique in recombinant protein expression/purification.

Crowe J, Döbeli H, Gentz R, Hochuli E, Stüber D, Henco K.

Methods Mol Biol. 1994;31:371-87. Review. No abstract available.

PMID:
7921034
22.

Rat brain glyceraldehyde-3-phosphate dehydrogenase interacts with the recombinant cytoplasmic domain of Alzheimer's beta-amyloid precursor protein.

Schulze H, Schuler A, Stüber D, Döbeli H, Langen H, Huber G.

J Neurochem. 1993 May;60(5):1915-22.

PMID:
8473906
23.

Selective inhibition of Plasmodium falciparum aldolase by a tubulin derived peptide and identification of the binding site.

Itin C, Burki Y, Certa U, Döbeli H.

Mol Biochem Parasitol. 1993 Mar;58(1):135-43.

PMID:
8459825
24.

1H, 13C, and 15N NMR backbone assignments and secondary structure of human interferon-gamma.

Grzesiek S, Döbeli H, Gentz R, Garotta G, Labhardt AM, Bax A.

Biochemistry. 1992 Sep 8;31(35):8180-90.

PMID:
1525157
25.

Stage-specific expression of aldolase isoenzymes in the rodent malaria parasite Plasmodium berghei.

Meier B, Döbeli H, Certa U.

Mol Biochem Parasitol. 1992 May;52(1):15-27.

PMID:
1625704
26.

In vitro mutagenesis defines drug targets in aldolase of Plasmodium falciparum.

Certa U, Itin C, Döbeli H.

Mem Inst Oswaldo Cruz. 1992;87 Suppl 3:263-4. Review. No abstract available.

27.

Comparative evaluation of an ELISA based on recombinant polypeptides and IFA for serology of malaria.

Srivastava IK, Schmidt M, Grall M, Yerly S, Garcia AM, Bouvier M, Takacs B, Dobeli H, Perrin LH.

J Trop Med Hyg. 1991 Jun;94(3):189-94.

PMID:
2051524
28.

Is Plasmodium falciparum aldolase useful for rational drug design?

Döbeli H, Itin C, Meier B, Certa U.

Acta Leiden. 1991;60(1):135-40.

PMID:
1820702
29.

Expression, purification, biochemical characterization and inhibition of recombinant Plasmodium falciparum aldolase.

Döbeli H, Trzeciak A, Gillessen D, Matile H, Srivastava IK, Perrin LH, Jakob PE, Certa U.

Mol Biochem Parasitol. 1990 Jun;41(2):259-68.

PMID:
2204832
30.

Immunization of Aotus monkeys with Plasmodium falciparum blood-stage recombinant proteins.

Herrera S, Herrera MA, Perlaza BL, Burki Y, Caspers P, Döbeli H, Rotmann D, Certa U.

Proc Natl Acad Sci U S A. 1990 May;87(10):4017-21.

31.

Initiation of translation at a UAG stop codon in the aldolase gene of Plasmodium falciparum.

Ghersa P, Shrivastava IK, Perrin LH, Döbeli H, Becherer DJ, Matile H, Meier B, Certa U.

EMBO J. 1990 May;9(5):1645-9.

32.

Specificity and inhibitory activity of antibodies to Plasmodium falciparum aldolase.

Srivastava IK, Schmidt M, Certa U, Döbeli H, Perrin LH.

J Immunol. 1990 Feb 15;144(4):1497-503.

PMID:
2406342
33.

Aldolase activity of a Plasmodium falciparum protein with protective properties.

Certa U, Ghersa P, Döbeli H, Matile H, Kocher HP, Shrivastava IK, Shaw AR, Perrin LH.

Science. 1988 May 20;240(4855):1036-8.

PMID:
3285469
34.

Major surface antigen p190 of Plasmodium falciparum: detection of common epitopes present in a variety of plasmodia isolates.

Gentz R, Certa U, Takacs B, Matile H, Döbeli H, Pink R, Mackay M, Bone N, Scaife JG.

EMBO J. 1988 Jan;7(1):225-30. Erratum in: EMBO J 1988 May;7(5):1558.

35.

New metal chelate adsorbent selective for proteins and peptides containing neighbouring histidine residues.

Hochuli E, Döbeli H, Schacher A.

J Chromatogr. 1987 Dec 18;411:177-84.

PMID:
3443622
36.

Inhibition of the reactivation of acid-dissociated lactate dehydrogenase isoenzymes by their aminoterminal CNBr fragments.

Döbeli H, Gillessen D, Lergier W, Van Dijk A, Schoenenberger GA.

Peptides. 1987 Sep-Oct;8(5):773-8.

PMID:
3432124
37.
39.

A factor isolated from liver inhibits reassociation/reactivation of dissociated glyceraldehyde-3-phosphate dehydrogenase.

Döbeli H, Schoenenberger GA.

FEBS Lett. 1981 Oct 12;133(1):123-6. No abstract available.

40.

Peptides isolated from human liver with specific inhibitory effects on reassociation/reactivation of in vitro dissociated lactic dehydrogenase (LDH-M4 and -H4) isozymes.

Schoenenberger GA, Buser S, Cueni L, Döbeli H, Gillesen D, Lergier W, Schöttli G, Tobler HJ, Wilson K.

Regul Pept. 1980 Dec;1(3):223-44.

PMID:
7232772
42.

On the Importance and Dangers of "Rest in Pulmonary Consumption.".

Dobeli H.

Br Med J. 1873 Nov 22;2(673):599-600. No abstract available.

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