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Items: 10


Trans-toxin ion-sensitivity of charybdotoxin-blocked potassium-channels reveals unbinding transitional states.

Moldenhauer H, Díaz-Franulic I, Poblete H, Naranjo D.

Elife. 2019 Jul 4;8. pii: e46170. doi: 10.7554/eLife.46170.


Gating-induced large aqueous volumetric remodeling and aspartate tolerance in the voltage sensor domain of Shaker K+ channels.

Díaz-Franulic I, González-Pérez V, Moldenhauer H, Navarro-Quezada N, Naranjo D.

Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8203-8208. doi: 10.1073/pnas.1806578115. Epub 2018 Jul 23.


Thermally activated TRP channels: molecular sensors for temperature detection.

Castillo K, Diaz-Franulic I, Canan J, Gonzalez-Nilo F, Latorre R.

Phys Biol. 2018 Jan 24;15(2):021001. doi: 10.1088/1478-3975/aa9a6f. Review.


Knockdown of Myo-Inositol Transporter SMIT1 Normalizes Cholinergic and Glutamatergic Function in an Immortalized Cell Line Established from the Cerebral Cortex of a Trisomy 16 Fetal Mouse, an Animal Model of Human Trisomy 21 (Down Syndrome).

Cárdenas AM, Fernández-Olivares P, Díaz-Franulic I, González-Jamett AM, Shimahara T, Segura-Aguilar J, Caviedes R, Caviedes P.

Neurotox Res. 2017 Nov;32(4):614-623. doi: 10.1007/s12640-017-9775-0. Epub 2017 Jul 10.


Pore size matters for potassium channel conductance.

Naranjo D, Moldenhauer H, Pincuntureo M, Díaz-Franulic I.

J Gen Physiol. 2016 Oct;148(4):277-91. doi: 10.1085/jgp.201611625. Epub 2016 Sep 12. Review.


Structure-Driven Pharmacology of Transient Receptor Potential Channel Vanilloid 1.

Díaz-Franulic I, Caceres-Molina J, Sepulveda RV, Gonzalez-Nilo F, Latorre R.

Mol Pharmacol. 2016 Sep;90(3):300-8. doi: 10.1124/mol.116.104430. Epub 2016 Jun 22. Review.


Allosterism and Structure in Thermally Activated Transient Receptor Potential Channels.

Diaz-Franulic I, Poblete H, Miño-Galaz G, González C, Latorre R.

Annu Rev Biophys. 2016 Jul 5;45:371-98. doi: 10.1146/annurev-biophys-062215-011034. Epub 2016 May 23. Review.


Effective pore size and radius of capture for K(+) ions in K-channels.

Moldenhauer H, Díaz-Franulic I, González-Nilo F, Naranjo D.

Sci Rep. 2016 Feb 2;6:19893. doi: 10.1038/srep19893.


Pore dimensions and the role of occupancy in unitary conductance of Shaker K channels.

Díaz-Franulic I, Sepúlveda RV, Navarro-Quezada N, González-Nilo F, Naranjo D.

J Gen Physiol. 2015 Aug;146(2):133-46. doi: 10.1085/jgp.201411353.


K⁺ conduction and Mg²⁺ blockade in a shaker Kv-channel single point mutant with an unusually high conductance.

Moscoso C, Vergara-Jaque A, Márquez-Miranda V, Sepúlveda RV, Valencia I, Díaz-Franulic I, González-Nilo F, Naranjo D.

Biophys J. 2012 Sep 19;103(6):1198-207. doi: 10.1016/j.bpj.2012.08.015.

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