Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 17

1.

Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity.

Czirr E, Castello NA, Mosher KI, Castellano JM, Hinkson IV, Lucin KM, Baeza-Raja B, Ryu JK, Li L, Farina SN, Belichenko NP, Longo FM, Akassoglou K, Britschgi M, Cirrito JR, Wyss-Coray T.

J Exp Med. 2017 Apr 3;214(4):1081-1092. doi: 10.1084/jem.20162011. Epub 2017 Mar 15.

2.

Preclinical Assessment of Young Blood Plasma for Alzheimer Disease.

Middeldorp J, Lehallier B, Villeda SA, Miedema SS, Evans E, Czirr E, Zhang H, Luo J, Stan T, Mosher KI, Masliah E, Wyss-Coray T.

JAMA Neurol. 2016 Nov 1;73(11):1325-1333. doi: 10.1001/jamaneurol.2016.3185.

3.

Autoimmunity contributes to nociceptive sensitization in a mouse model of complex regional pain syndrome.

Li WW, Guo TZ, Shi X, Czirr E, Stan T, Sahbaie P, Wyss-Coray T, Kingery WS, Clark JD.

Pain. 2014 Nov;155(11):2377-89. doi: 10.1016/j.pain.2014.09.007. Epub 2014 Sep 10.

4.

TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis.

Kleinberger G, Yamanishi Y, Suárez-Calvet M, Czirr E, Lohmann E, Cuyvers E, Struyfs H, Pettkus N, Wenninger-Weinzierl A, Mazaheri F, Tahirovic S, Lleó A, Alcolea D, Fortea J, Willem M, Lammich S, Molinuevo JL, Sánchez-Valle R, Antonell A, Ramirez A, Heneka MT, Sleegers K, van der Zee J, Martin JJ, Engelborghs S, Demirtas-Tatlidede A, Zetterberg H, Van Broeckhoven C, Gurvit H, Wyss-Coray T, Hardy J, Colonna M, Haass C.

Sci Transl Med. 2014 Jul 2;6(243):243ra86. doi: 10.1126/scitranslmed.3009093.

5.

Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer's disease.

Lucin KM, O'Brien CE, Bieri G, Czirr E, Mosher KI, Abbey RJ, Mastroeni DF, Rogers J, Spencer B, Masliah E, Wyss-Coray T.

Neuron. 2013 Sep 4;79(5):873-86. doi: 10.1016/j.neuron.2013.06.046.

6.

The immunology of neurodegeneration.

Czirr E, Wyss-Coray T.

J Clin Invest. 2012 Apr;122(4):1156-63. doi: 10.1172/JCI58656. Epub 2012 Apr 2. Review.

7.

The ageing systemic milieu negatively regulates neurogenesis and cognitive function.

Villeda SA, Luo J, Mosher KI, Zou B, Britschgi M, Bieri G, Stan TM, Fainberg N, Ding Z, Eggel A, Lucin KM, Czirr E, Park JS, Couillard-Després S, Aigner L, Li G, Peskind ER, Kaye JA, Quinn JF, Galasko DR, Xie XS, Rando TA, Wyss-Coray T.

Nature. 2011 Aug 31;477(7362):90-4. doi: 10.1038/nature10357.

8.

Presenilin-1 but not amyloid precursor protein mutations present in mouse models of Alzheimer's disease attenuate the response of cultured cells to γ-secretase modulators regardless of their potency and structure.

Hahn S, Brüning T, Ness J, Czirr E, Baches S, Gijsen H, Korth C, Pietrzik CU, Bulic B, Weggen S.

J Neurochem. 2011 Feb;116(3):385-95. doi: 10.1111/j.1471-4159.2010.07118.x. Epub 2010 Dec 13.

9.

alpha-secretase mediated conversion of the amyloid precursor protein derived membrane stub C99 to C83 limits Abeta generation.

Jäger S, Leuchtenberger S, Martin A, Czirr E, Wesselowski J, Dieckmann M, Waldron E, Korth C, Koo EH, Heneka M, Weggen S, Pietrzik CU.

J Neurochem. 2009 Dec;111(6):1369-82. doi: 10.1111/j.1471-4159.2009.06420.x.

10.

Independent generation of Abeta42 and Abeta38 peptide species by gamma-secretase.

Czirr E, Cottrell BA, Leuchtenberger S, Kukar T, Ladd TB, Esselmann H, Paul S, Schubenel R, Torpey JW, Pietrzik CU, Golde TE, Wiltfang J, Baumann K, Koo EH, Weggen S.

J Biol Chem. 2008 Jun 20;283(25):17049-54. doi: 10.1074/jbc.M802912200. Epub 2008 Apr 21.

11.

Nonsteroidal anti-inflammatory drugs and ectodomain shedding of the amyloid precursor protein.

Leuchtenberger S, Maler J, Czirr E, Ness J, Lichtenthaler SF, Esselmann H, Pietrzik CU, Wiltfang J, Weggen S.

Neurodegener Dis. 2009;6(1-2):1-8. doi: 10.1159/000121391. Epub 2008 Mar 18.

PMID:
18349521
12.

Insensitivity to Abeta42-lowering nonsteroidal anti-inflammatory drugs and gamma-secretase inhibitors is common among aggressive presenilin-1 mutations.

Czirr E, Leuchtenberger S, Dorner-Ciossek C, Schneider A, Jucker M, Koo EH, Pietrzik CU, Baumann K, Weggen S.

J Biol Chem. 2007 Aug 24;282(34):24504-13. Epub 2007 Jun 15.

13.
14.

Inhibitors of Rho-kinase modulate amyloid-beta (Abeta) secretion but lack selectivity for Abeta42.

Leuchtenberger S, Kummer MP, Kukar T, Czirr E, Teusch N, Sagi SA, Berdeaux R, Pietrzik CU, Ladd TB, Golde TE, Koo EH, Weggen S.

J Neurochem. 2006 Jan;96(2):355-65. Epub 2005 Nov 21.

15.

Outer dense fibre protein 2 (ODF2) is a self-interacting centrosomal protein with affinity for microtubules.

Donkor FF, Mönnich M, Czirr E, Hollemann T, Hoyer-Fender S.

J Cell Sci. 2004 Sep 15;117(Pt 20):4643-51. Epub 2004 Aug 31.

16.

Genetic variation in oocyte phenotype revealed through parthenogenesis and cloning: correlation with differences in pronuclear epigenetic modification.

Gao S, Czirr E, Chung YG, Han Z, Latham KE.

Biol Reprod. 2004 Apr;70(4):1162-70. Epub 2003 Dec 17.

PMID:
14681201
17.

Localisation of histone macroH2A1.2 to the XY-body is not a response to the presence of asynapsed chromosome axes.

Hoyer-Fender S, Czirr E, Radde R, Turner JM, Mahadevaiah SK, Pehrson JR, Burgoyne PS.

J Cell Sci. 2004 Jan 15;117(Pt 2):189-98.

Supplemental Content

Support Center