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Items: 1 to 50 of 82

1.

Structural domains involved in the regulation of transmitter release by synapsins.

Hilfiker S, Benfenati F, Doussau F, Nairn AC, Czernik AJ, Augustine GJ, Greengard P.

J Neurosci. 2005 Mar 9;25(10):2658-69.

2.

Spatial and temporal regulation of Ca2+/calmodulin-dependent protein kinase II activity in developing neurons.

Menegon A, Verderio C, Leoni C, Benfenati F, Czernik AJ, Greengard P, Matteoli M, Valtorta F.

J Neurosci. 2002 Aug 15;22(16):7016-26.

3.

A protein kinase A-dependent molecular switch in synapsins regulates neurite outgrowth.

Kao HT, Song HJ, Porton B, Ming GL, Hoh J, Abraham M, Czernik AJ, Pieribone VA, Poo MM, Greengard P.

Nat Neurosci. 2002 May;5(5):431-7.

PMID:
11976703
4.

Bidirectional changes in synapsin I phosphorylation at MAP kinase-dependent sites by acute neuronal excitation in vivo.

Yamagata Y, Jovanovic JN, Czernik AJ, Greengard P, Obata K.

J Neurochem. 2002 Mar;80(5):835-42.

5.

Neuronal nitric-oxide synthase localization mediated by a ternary complex with synapsin and CAPON.

Jaffrey SR, Benfenati F, Snowman AM, Czernik AJ, Snyder SH.

Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3199-204. Epub 2002 Feb 26.

6.

Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+-dependent glutamate release in isolated nerve terminals.

Jovanovic JN, Sihra TS, Nairn AC, Hemmings HC Jr, Greengard P, Czernik AJ.

J Neurosci. 2001 Oct 15;21(20):7944-53.

7.

ARPP-16/ARPP-19: a highly conserved family of cAMP-regulated phosphoproteins.

Dulubova I, Horiuchi A, Snyder GL, Girault JA, Czernik AJ, Shao L, Ramabhadran R, Greengard P, Nairn AC.

J Neurochem. 2001 Apr;77(1):229-38.

8.

Phosphorylation of protein phosphatase inhibitor-1 by Cdk5.

Bibb JA, Nishi A, O'Callaghan JP, Ule J, Lan M, Snyder GL, Horiuchi A, Saito T, Hisanaga S, Czernik AJ, Nairn AC, Greengard P.

J Biol Chem. 2001 Apr 27;276(17):14490-7. Epub 2001 Jan 29.

9.

Tonically active protein kinase A regulates neurotransmitter release at the squid giant synapse.

Hilfiker S, Czernik AJ, Greengard P, Augustine GJ.

J Physiol. 2001 Feb 15;531(Pt 1):141-6.

10.

Identification of synapsin I peptides that insert into lipid membranes.

Cheetham JJ, Hilfiker S, Benfenati F, Weber T, Greengard P, Czernik AJ.

Biochem J. 2001 Feb 15;354(Pt 1):57-66.

11.

Use of phosphosynapsin I-specific antibodies for image analysis of signal transduction in single nerve terminals.

Menegon A, Dunlap DD, Castano F, Benfenati F, Czernik AJ, Greengard P, Valtorta F.

J Cell Sci. 2000 Oct;113 ( Pt 20):3573-82.

12.

Synapsins as mediators of BDNF-enhanced neurotransmitter release.

Jovanovic JN, Czernik AJ, Fienberg AA, Greengard P, Sihra TS.

Nat Neurosci. 2000 Apr;3(4):323-9.

PMID:
10725920
13.

Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons.

Bibb JA, Snyder GL, Nishi A, Yan Z, Meijer L, Fienberg AA, Tsai LH, Kwon YT, Girault JA, Czernik AJ, Huganir RL, Hemmings HC Jr, Nairn AC, Greengard P.

Nature. 1999 Dec 9;402(6762):669-71.

PMID:
10604473
14.

Synapsins as major neuronal Ca2+/S100A1-interacting proteins.

Heierhorst J, Mitchelhill KI, Mann RJ, Tiganis T, Czernik AJ, Greengard P, Kemp BE.

Biochem J. 1999 Dec 1;344 Pt 2:577-83.

15.

Regulation of synaptotagmin I phosphorylation by multiple protein kinases.

Hilfiker S, Pieribone VA, Nordstedt C, Greengard P, Czernik AJ.

J Neurochem. 1999 Sep;73(3):921-32.

16.

Phylogenetically conserved CK-II phosphorylation site of the murine homeodomain protein Hoxb-6.

Fienberg AA, Nordstedt C, Belting HG, Czernik AJ, Nairn AC, Gandy S, Greengard P, Ruddle FH.

J Exp Zool. 1999 Apr 15;285(1):76-84.

PMID:
10327653
17.

Phosphorylation of the cytoplasmic domain of Alzheimer's beta-amyloid precursor protein at Ser655 by a novel protein kinase.

Isohara T, Horiuchi A, Watanabe T, Ando K, Czernik AJ, Uno I, Greengard P, Nairn AC, Suzuki T.

Biochem Biophys Res Commun. 1999 May 10;258(2):300-5.

PMID:
10329382
18.

Synapsins as regulators of neurotransmitter release.

Hilfiker S, Pieribone VA, Czernik AJ, Kao HT, Augustine GJ, Greengard P.

Philos Trans R Soc Lond B Biol Sci. 1999 Feb 28;354(1381):269-79. Review.

19.

Two sites of action for synapsin domain E in regulating neurotransmitter release.

Hilfiker S, Schweizer FE, Kao HT, Czernik AJ, Greengard P, Augustine GJ.

Nat Neurosci. 1998 May;1(1):29-35. Erratum in: Nat Neurosci 1998 Aug;1(4):329.

PMID:
10195105
20.

Ca2+/calmodulin-dependent kinase II mediates simultaneous enhancement of gap-junctional conductance and glutamatergic transmission.

Pereda AE, Bell TD, Chang BH, Czernik AJ, Nairn AC, Soderling TR, Faber DS.

Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):13272-7.

21.

A third member of the synapsin gene family.

Kao HT, Porton B, Czernik AJ, Feng J, Yiu G, Häring M, Benfenati F, Greengard P.

Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4667-72.

22.

Regulation of secretion of Alzheimer amyloid precursor protein by the mitogen-activated protein kinase cascade.

Desdouits-Magnen J, Desdouits F, Takeda S, Syu LJ, Saltiel AR, Buxbaum JD, Czernik AJ, Nairn AC, Greengard P.

J Neurochem. 1998 Feb;70(2):524-30.

23.

Synapsin I interacts with c-Src and stimulates its tyrosine kinase activity.

Onofri F, Giovedì S, Vaccaro P, Czernik AJ, Valtorta F, De Camilli P, Greengard P, Benfenati F.

Proc Natl Acad Sci U S A. 1997 Oct 28;94(22):12168-73.

24.

Phosphorylation of connexin43 and the regulation of neonatal rat cardiac myocyte gap junctions.

Sáez JC, Nairn AC, Czernik AJ, Fishman GI, Spray DC, Hertzberg EL.

J Mol Cell Cardiol. 1997 Aug;29(8):2131-45.

PMID:
9281445
25.

Glutamate-dependent phosphorylation of elongation factor-2 and inhibition of protein synthesis in neurons.

Marin P, Nastiuk KL, Daniel N, Girault JA, Czernik AJ, Glowinski J, Nairn AC, Prémont J.

J Neurosci. 1997 May 15;17(10):3445-54.

26.

Evidence for phosphorylation and oligomeric assembly of presenilin 1.

Seeger M, Nordstedt C, Petanceska S, Kovacs DM, Gouras GK, Hahne S, Fraser P, Levesque L, Czernik AJ, George-Hyslop PS, Sisodia SS, Thinakaran G, Tanzi RE, Greengard P, Gandy S.

Proc Natl Acad Sci U S A. 1997 May 13;94(10):5090-4.

27.

The cytoplasmic domain of Alzheimer's amyloid precursor protein is phosphorylated at Thr654, Ser655, and Thr668 in adult rat brain and cultured cells.

Oishi M, Nairn AC, Czernik AJ, Lim GS, Isohara T, Gandy SE, Greengard P, Suzuki T.

Mol Med. 1997 Feb;3(2):111-23.

28.

Expression of synapsin I correlates with maturation of the neuromuscular synapse.

Lu B, Czernik AJ, Popov S, Wang T, Poo MM, Greengard P.

Neuroscience. 1996 Oct;74(4):1087-97.

PMID:
8895877
29.

Biochemical and functional characterization of the synaptic vesicle-associated form of CA2+/calmodulin-dependent protein kinase II.

Benfenati F, Onofri F, Czernik AJ, Valtorta F.

Brain Res Mol Brain Res. 1996 Sep 1;40(2):297-309.

PMID:
8872314
30.

Increased in vivo phosphorylation state of neuromodulin and synapsin I in striatum from rats treated with repeated amphetamine.

Iwata S, Hewlett GH, Ferrell ST, Czernik AJ, Meiri KF, Gnegy ME.

J Pharmacol Exp Ther. 1996 Sep;278(3):1428-34.

PMID:
8819530
31.

Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions.

Jovanovic JN, Benfenati F, Siow YL, Sihra TS, Sanghera JS, Pelech SL, Greengard P, Czernik AJ.

Proc Natl Acad Sci U S A. 1996 Apr 16;93(8):3679-83.

32.

Anti-immunoglobulin M activates nuclear calcium/calmodulin-dependent protein kinase II in human B lymphocytes.

Valentine MA, Czernik AJ, Rachie N, Hidaka H, Fisher CL, Cambier JC, Bomsztyk K.

J Exp Med. 1995 Dec 1;182(6):1943-9.

33.

Distinct pools of synaptic vesicles in neurotransmitter release.

Pieribone VA, Shupliakov O, Brodin L, Hilfiker-Rothenfluh S, Czernik AJ, Greengard P.

Nature. 1995 Jun 8;375(6531):493-7.

PMID:
7777058
34.

Calmodulin-dependent protein kinases in rat glioblastoma.

Cheng EH, Gorelick FS, Czernik AJ, Bagaglio DM, Hait WN.

Cell Growth Differ. 1995 May;6(5):615-21.

35.

Increase in synapsin I phosphorylation implicates a presynaptic component in septal kindling.

Yamagata Y, Obata K, Greengard P, Czernik AJ.

Neuroscience. 1995 Jan;64(1):1-4.

PMID:
7708197
37.

Antibodies to an epitope on synapsin I detect a protein associated with the endocytic compartment in non-neuronal cells.

Matovcik LM, Karapetian O, Czernik AJ, Marino CR, Kinder BK, Gorelick FS.

Eur J Cell Biol. 1994 Dec;65(2):327-40.

PMID:
7536673
38.

Calcium/calmodulin-dependent protein kinase II immunostaining is preserved in Alzheimer's disease hippocampal neurons.

Simonian NA, Elvhage T, Czernik AJ, Greengard P, Hyman BT.

Brain Res. 1994 Sep 19;657(1-2):294-9.

PMID:
7820630
39.

Interaction of Grb2 via its Src homology 3 domains with synaptic proteins including synapsin I.

McPherson PS, Czernik AJ, Chilcote TJ, Onofri F, Benfenati F, Greengard P, Schlessinger J, De Camilli P.

Proc Natl Acad Sci U S A. 1994 Jul 5;91(14):6486-90.

40.

Specificity of protein kinase inhibitor peptides and induction of long-term potentiation.

Hvalby O, Hemmings HC Jr, Paulsen O, Czernik AJ, Nairn AC, Godfraind JM, Jensen V, Raastad M, Storm JF, Andersen P, et al.

Proc Natl Acad Sci U S A. 1994 May 24;91(11):4761-5.

42.

Identification of the phosphorylation site for cAMP-dependent protein kinase on Na+,K(+)-ATPase and effects of site-directed mutagenesis.

Fisone G, Cheng SX, Nairn AC, Czernik AJ, Hemmings HC Jr, Höög JO, Bertorello AM, Kaiser R, Bergman T, Jörnvall H, et al.

J Biol Chem. 1994 Mar 25;269(12):9368-73.

43.

Cell cycle-dependent regulation of the phosphorylation and metabolism of the Alzheimer amyloid precursor protein.

Suzuki T, Oishi M, Marshak DR, Czernik AJ, Nairn AC, Greengard P.

EMBO J. 1994 Mar 1;13(5):1114-22.

44.

Calcium/calmodulin-dependent protein kinase I. cDNA cloning and identification of autophosphorylation site.

Picciotto MR, Czernik AJ, Nairn AC.

J Biol Chem. 1993 Dec 15;268(35):26512-21. Erratum in: J Biol Chem 1995 Apr 28;270(17):10358.

45.

Protein phosphorylation regulates relative utilization of processing pathways for Alzheimer beta/A4 amyloid precursor protein.

Gandy SE, Caporaso GL, Buxbaum JD, de Cruz Silva O, Iverfeldt K, Nordstedt C, Suzuki T, Czernik AJ, Nairn AC, Greengard P.

Ann N Y Acad Sci. 1993 Sep 24;695:117-21. Review.

PMID:
8239268
46.

Distribution of calcium/calmodulin-dependent protein kinase II in rat ileal enterocytes.

Matovcik LM, Haimowitz B, Goldenring JR, Czernik AJ, Gorelick FS.

Am J Physiol. 1993 Apr;264(4 Pt 1):C1029-36.

PMID:
8386447
47.

Synaptic vesicle phosphoproteins and regulation of synaptic function.

Greengard P, Valtorta F, Czernik AJ, Benfenati F.

Science. 1993 Feb 5;259(5096):780-5. Review.

PMID:
8430330
48.

Calcium-dependent serine phosphorylation of synaptophysin.

Rubenstein JL, Greengard P, Czernik AJ.

Synapse. 1993 Feb;13(2):161-72.

PMID:
8383357
49.

Proteolytic processing of human amyloid beta protein precursor in insect cells. Major carboxyl-terminal fragment is identical to its human counterpart.

Ramabhadran TV, Gandy SE, Ghiso J, Czernik AJ, Ferris D, Bhasin R, Goldgaber D, Frangione B, Greengard P.

J Biol Chem. 1993 Jan 25;268(3):2009-12.

50.

Characterization of alternative routes for processing of the Alzheimer beta/A4-amyloid precursor protein. Differential effects of phorbol esters and chloroquine.

Gandy SE, Caporaso GL, Ramabhadran TV, Suzuki T, Buxbaum JD, Nordstedt C, Iverfeldt K, Czernik AJ, Nairn AC, Greengard P.

Ann N Y Acad Sci. 1992 Dec 31;674:203-17. Review. No abstract available.

PMID:
1363189

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