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Association of DAT1 Genetic Variants with Habitual Sleep Duration in the UK Biobank.

Rhodes JA, Lane JM, Vlasac IM, Rutter MK, Czeisler C, Saxena R.

Sleep. 2018 Oct 8. doi: 10.1093/sleep/zsy193. [Epub ahead of print]


Cross-sectional analysis of sleep-promoting and wake-promoting drug use on health, fatigue-related error, and near-crashes in police officers.

Ogeil RP, Barger LK, Lockley SW, O'Brien CS, Sullivan JP, Qadri S, Lubman DI, Czeisler CA, Rajaratnam SMW.

BMJ Open. 2018 Sep 19;8(9):e022041. doi: 10.1136/bmjopen-2018-022041.


Development of a Novel FIJI-Based Method to Investigate Neuronal Circuitry in Neonatal Mice.

Mei-Ling Liu J, Fair SR, Kaya B, Zuniga JN, Mostafa HR, Alves MJ, Stephens JA, Jones M, Aslan MT, Czeisler C, Otero JJ.

Dev Neurobiol. 2018 Aug 23. doi: 10.1002/dneu.22636. [Epub ahead of print]


Sleep disorders, depression and anxiety are associated with adverse safety outcomes in healthcare workers: A prospective cohort study.

Weaver MD, Vetter C, Rajaratnam SMW, O'Brien CS, Qadri S, Benca RM, Rogers AE, Leary EB, Walsh JK, Czeisler CA, Barger LK.

J Sleep Res. 2018 Aug 1:e12722. doi: 10.1111/jsr.12722. [Epub ahead of print]


Young adults are more vulnerable to chronic sleep deficiency and recurrent circadian disruption than older adults.

Zitting KM, Münch MY, Cain SW, Wang W, Wong A, Ronda JM, Aeschbach D, Czeisler CA, Duffy JF.

Sci Rep. 2018 Jul 23;8(1):11052. doi: 10.1038/s41598-018-29358-x.


Sleep Education for College Students: The Time Is Now.

Quan SF, Ziporyn PS, Czeisler CA.

J Clin Sleep Med. 2018 Jul 15;14(7):1269. doi: 10.5664/jcsm.7246. No abstract available.


Housing Immigrant Children - The Inhumanity of Constant Illumination.

Czeisler CA.

N Engl J Med. 2018 Jul 12;379(2):e3. doi: 10.1056/NEJMp1808450. Epub 2018 Jun 22. No abstract available.


Resident physician extended work hours and burnout.

McHill AW, Czeisler CA, Shea SA.

Sleep. 2018 Aug 1;41(8). doi: 10.1093/sleep/zsy112. No abstract available.


Unrestricted evening use of light-emitting tablet computers delays self-selected bedtime and disrupts circadian timing and alertness.

Chinoy ED, Duffy JF, Czeisler CA.

Physiol Rep. 2018 May;6(10):e13692. doi: 10.14814/phy2.13692.


Increased vulnerability to attentional failure during acute sleep deprivation in women depends on menstrual phase.

Vidafar P, Gooley JJ, Burns AC, Rajaratnam SMW, Rueger M, Van Reen E, Czeisler CA, Lockley SW, Cain SW.

Sleep. 2018 Aug 1;41(8). doi: 10.1093/sleep/zsy098.


Chronic sleep curtailment, even without extended (>16-h) wakefulness, degrades human vigilance performance.

McHill AW, Hull JT, Wang W, Czeisler CA, Klerman EB.

Proc Natl Acad Sci U S A. 2018 Jun 5;115(23):6070-6075. doi: 10.1073/pnas.1706694115. Epub 2018 May 21.


Functional decoupling of melatonin suppression and circadian phase resetting in humans.

Rahman SA, St Hilaire MA, Gronfier C, Chang AM, Santhi N, Czeisler CA, Klerman EB, Lockley SW.

J Physiol. 2018 Jun;596(11):2147-2157. doi: 10.1113/JP275501. Epub 2018 Apr 29.


Suppression of Melatonin Secretion in Totally Visually Blind People by Ocular Exposure to White Light: Clinical Characteristics.

Hull JT, Czeisler CA, Lockley SW.

Ophthalmology. 2018 Aug;125(8):1160-1171. doi: 10.1016/j.ophtha.2018.01.036. Epub 2018 Apr 4.


Sleep deficiency and motor vehicle crash risk in the general population: a prospective cohort study.

Gottlieb DJ, Ellenbogen JM, Bianchi MT, Czeisler CA.

BMC Med. 2018 Mar 20;16(1):44. doi: 10.1186/s12916-018-1025-7.


Data and methods for studying commercial motor vehicle driver fatigue, highway safety and long-term driver health.

Stern HS, Blower D, Cohen ML, Czeisler CA, Dinges DF, Greenhouse JB, Guo F, Hanowski RJ, Hartenbaum NP, Krueger GP, Mallis MM, Pain RF, Rizzo M, Sinha E, Small DS, Stuart EA, Wegman DH.

Accid Anal Prev. 2018 Mar 9. pii: S0001-4575(18)30083-6. doi: 10.1016/j.aap.2018.02.021. [Epub ahead of print]


Micelle-templated, poly(lactic-co-glycolic acid) nanoparticles for hydrophobic drug delivery.

Nabar GM, Mahajan KD, Calhoun MA, Duong AD, Souva MS, Xu J, Czeisler C, Puduvalli VK, Otero JJ, Wyslouzil BE, Winter JO.

Int J Nanomedicine. 2018 Jan 10;13:351-366. doi: 10.2147/IJN.S142079. eCollection 2018.


Self-reported drowsiness and safety outcomes while driving after an extended duration work shift in trainee physicians.

Anderson C, Ftouni S, Ronda JM, Rajaratnam SMW, Czeisler CA, Lockley SW.

Sleep. 2017 Dec 22. doi: 10.1093/sleep/zsx195. [Epub ahead of print]


Prediction of drowsiness events in night shift workers during morning driving.

Liang Y, Horrey WJ, Howard ME, Lee ML, Anderson C, Shreeve MS, O'Brien CS, Czeisler CA.

Accid Anal Prev. 2017 Nov 7. pii: S0001-4575(17)30391-3. doi: 10.1016/j.aap.2017.11.004. [Epub ahead of print]


Short Sleep Duration, Obstructive Sleep Apnea, Shiftwork, and the Risk of Adverse Cardiovascular Events in Patients After an Acute Coronary Syndrome.

Barger LK, Rajaratnam SMW, Cannon CP, Lukas MA, Im K, Goodrich EL, Czeisler CA, O'Donoghue ML.

J Am Heart Assoc. 2017 Oct 10;6(10). pii: e006959. doi: 10.1161/JAHA.117.006959.


Bone Turnover Markers After Sleep Restriction and Circadian Disruption: A Mechanism for Sleep-Related Bone Loss in Humans.

Swanson CM, Shea SA, Wolfe P, Cain SW, Munch M, Vujovic N, Czeisler CA, Buxton OM, Orwoll ES.

J Clin Endocrinol Metab. 2017 Oct 1;102(10):3722-3730. doi: 10.1210/jc.2017-01147.


Impaired cognitive flexibility during sleep deprivation among carriers of the Brain Derived Neurotrophic Factor (BDNF) Val66Met allele.

Grant LK, Cain SW, Chang AM, Saxena R, Czeisler CA, Anderson C.

Behav Brain Res. 2018 Feb 15;338:51-55. doi: 10.1016/j.bbr.2017.09.025. Epub 2017 Sep 22.


Later circadian timing of food intake is associated with increased body fat.

McHill AW, Phillips AJ, Czeisler CA, Keating L, Yee K, Barger LK, Garaulet M, Scheer FA, Klerman EB.

Am J Clin Nutr. 2017 Nov;106(5):1213-1219. doi: 10.3945/ajcn.117.161588. Epub 2017 Sep 6.


Soluble interleukin-13rα1: a circulating regulator of glucose.

Rachmin I, O'Meara CC, Ricci-Blair EM, Feng Y, Christensen EM, Duffy JF, Zitting KM, Czeisler CA, Pancoast JR, Cannon CP, O'Donoghue ML, Morrow DA, Lee RT.

Am J Physiol Endocrinol Metab. 2017 Dec 1;313(6):E663-E671. doi: 10.1152/ajpendo.00168.2017. Epub 2017 Sep 5.


24-hour profile of serum sclerostin and its association with bone biomarkers in men.

Swanson C, Shea SA, Wolfe P, Markwardt S, Cain SW, Munch M, Czeisler CA, Orwoll ES, Buxton OM.

Osteoporos Int. 2017 Nov;28(11):3205-3213. doi: 10.1007/s00198-017-4162-5. Epub 2017 Jul 26.


Irregular sleep/wake patterns are associated with poorer academic performance and delayed circadian and sleep/wake timing.

Phillips AJK, Clerx WM, O'Brien CS, Sano A, Barger LK, Picard RW, Lockley SW, Klerman EB, Czeisler CA.

Sci Rep. 2017 Jun 12;7(1):3216. doi: 10.1038/s41598-017-03171-4.


Circadian phase resetting by a single short-duration light exposure.

Rahman SA, St Hilaire MA, Chang AM, Santhi N, Duffy JF, Kronauer RE, Czeisler CA, Lockley SW, Klerman EB.

JCI Insight. 2017 Apr 6;2(7):e89494. doi: 10.1172/jci.insight.89494.


Asleep at the Wheel-The Road to Addressing Drowsy Driving.

Higgins JS, Michael J, Austin R, Åkerstedt T, Van Dongen HP, Watson N, Czeisler C, Pack AI, Rosekind MR.

Sleep. 2017 Feb 1;40(2). doi: 10.1093/sleep/zsx001.


Randomized, Prospective Study of the Impact of a Sleep Health Program on Firefighter Injury and Disability.

Sullivan JP, O'Brien CS, Barger LK, Rajaratnam SM, Czeisler CA, Lockley SW; Harvard Work Hours, Health and Safety Group.

Sleep. 2017 Jan 1;40(1). doi: 10.1093/sleep/zsw001.


Circadian Rhythms in Plasma Brain-derived Neurotrophic Factor Differ in Men and Women.

Cain SW, Chang AM, Vlasac I, Tare A, Anderson C, Czeisler CA, Saxena R.

J Biol Rhythms. 2017 Feb;32(1):75-82. doi: 10.1177/0748730417693124. Epub 2017 Feb 20.


Imaging Cell-Matrix Interactions in 3D Collagen Hydrogel Culture Systems.

Short AR, Czeisler C, Stocker B, Cole S, Otero JJ, Winter JO.

Macromol Biosci. 2017 Jun;17(6). doi: 10.1002/mabi.201600478. Epub 2017 Feb 21.


Noncontact Pressure-Based Sleep/Wake Discrimination.

Walsh L, McLoone S, Ronda J, Duffy JF, Czeisler CA.

IEEE Trans Biomed Eng. 2017 Aug;64(8):1750-1760. doi: 10.1109/TBME.2016.2621066. Epub 2016 Oct 25.


Problems Associated With Use of Mobile Devices in the Sleep Environment-Streaming Instead of Dreaming.

Czeisler CA, Shanahan TL.

JAMA Pediatr. 2016 Dec 1;170(12):1146-1147. doi: 10.1001/jamapediatrics.2016.2986. No abstract available.


SLEEP. Measuring the passage of brain time.

Czeisler CA.

Science. 2016 Aug 12;353(6300):648-9. doi: 10.1126/science.aah5402. No abstract available.


Pineal Gland Volume Assessed by MRI and Its Correlation with 6-Sulfatoxymelatonin Levels among Older Men.

Sigurdardottir LG, Markt SC, Sigurdsson S, Aspelund T, Fall K, Schernhammer E, Rider JR, Launer L, Harris T, Stampfer MJ, Gudnason V, Czeisler CA, Lockley SW, Valdimarsdottir UA, Mucci LA.

J Biol Rhythms. 2016 Oct;31(5):461-9. doi: 10.1177/0748730416656948. Epub 2016 Jul 22.


Cyclin A2 promotes DNA repair in the brain during both development and aging.

Gygli PE, Chang JC, Gokozan HN, Catacutan FP, Schmidt TA, Kaya B, Goksel M, Baig FS, Chen S, Griveau A, Michowski W, Wong M, Palanichamy K, Sicinski P, Nelson RJ, Czeisler C, Otero JJ.

Aging (Albany NY). 2016 Jul;8(7):1540-70. doi: 10.18632/aging.100990.


Surface topography during neural stem cell differentiation regulates cell migration and cell morphology.

Czeisler C, Short A, Nelson T, Gygli P, Ortiz C, Catacutan FP, Stocker B, Cronin J, Lannutti J, Winter J, Otero JJ.

J Comp Neurol. 2016 Dec 1;524(17):3485-3502. doi: 10.1002/cne.24078. Epub 2016 Aug 18.


Sleep-deprived motor vehicle operators are unfit to drive: a multidisciplinary expert consensus statement on drowsy driving.

Czeisler CA, Wickwire EM, Barger LK, Dement WC, Gamble K, Hartenbaum N, Ohayon MM, Pelayo R, Phillips B, Strohl K, Tefft B, Rajaratnam SMW, Malhotra R, Whiton K, Hirshkowitz M.

Sleep Health. 2016 Jun;2(2):94-99. doi: 10.1016/j.sleh.2016.04.003. Epub 2016 May 10.


Respiratory and autonomic dysfunction in congenital central hypoventilation syndrome.

Moreira TS, Takakura AC, Czeisler C, Otero JJ.

J Neurophysiol. 2016 Aug 1;116(2):742-52. doi: 10.1152/jn.00026.2016. Epub 2016 May 25. Review.


Obstructive Sleep Apnea and Work Accidents: Time for Action.

Kales SN, Czeisler CA.

Sleep. 2016 Jun 1;39(6):1171-3. doi: 10.5665/sleep.5822. No abstract available.


Circadian gene variants influence sleep and the sleep electroencephalogram in humans.

Chang AM, Bjonnes AC, Aeschbach D, Buxton OM, Gooley JJ, Anderson C, Van Reen E, Cain SW, Czeisler CA, Duffy JF, Lockley SW, Shea SA, Scheer FA, Saxena R.

Chronobiol Int. 2016;33(5):561-73. doi: 10.3109/07420528.2016.1167078. Epub 2016 Apr 18.


Nonadherence with Employer-Mandated Sleep Apnea Treatment and Increased Risk of Serious Truck Crashes.

Burks SV, Anderson JE, Bombyk M, Haider R, Ganzhorn D, Jiao X, Lewis C, Lexvold A, Liu H, Ning J, Toll A, Hickman JS, Mabry E, Berger M, Malhotra A, Czeisler CA, Kales SN.

Sleep. 2016 May 1;39(5):967-75. doi: 10.5665/sleep.5734.


Ancestral sleep.

de la Iglesia HO, Moreno C, Lowden A, Louzada F, Marqueze E, Levandovski R, Pilz LK, Valeggia C, Fernandez-Duque E, Golombek DA, Czeisler CA, Skene DJ, Duffy JF, Roenneberg T.

Curr Biol. 2016 Apr 4;26(7):R271-2. doi: 10.1016/j.cub.2016.01.071.


Implementing a Sleep Health Education and Sleep Disorders Screening Program in Fire Departments: A Comparison of Methodology.

Barger LK, O'Brien CS, Rajaratnam SM, Qadri S, Sullivan JP, Wang W, Czeisler CA, Lockley SW.

J Occup Environ Med. 2016 Jun;58(6):601-9. doi: 10.1097/JOM.0000000000000709.


Prediction of Vigilant Attention and Cognitive Performance Using Self-Reported Alertness, Circadian Phase, Hours since Awakening, and Accumulated Sleep Loss.

Bermudez EB, Klerman EB, Czeisler CA, Cohen DA, Wyatt JK, Phillips AJ.

PLoS One. 2016 Mar 28;11(3):e0151770. doi: 10.1371/journal.pone.0151770. eCollection 2016.


Impact of Common Diabetes Risk Variant in MTNR1B on Sleep, Circadian, and Melatonin Physiology.

Lane JM, Chang AM, Bjonnes AC, Aeschbach D, Anderson C, Cade BE, Cain SW, Czeisler CA, Gharib SA, Gooley JJ, Gottlieb DJ, Grant SF, Klerman EB, Lauderdale DS, Lockley SW, Munch M, Patel S, Punjabi NM, Rajaratnam SM, Rueger M, St Hilaire MA, Santhi N, Scheuermaier K, Van Reen E, Zee PC, Shea SA, Duffy JF, Buxton OM, Redline S, Scheer FA, Saxena R.

Diabetes. 2016 Jun;65(6):1741-51. doi: 10.2337/db15-0999. Epub 2016 Feb 11.


Circadian misalignment affects sleep and medication use before and during spaceflight.

Flynn-Evans EE, Barger LK, Kubey AA, Sullivan JP, Czeisler CA.

NPJ Microgravity. 2016 Jan 7;2:15019. doi: 10.1038/npjmgrav.2015.19. eCollection 2016.


Deterministic transfection drives efficient nonviral reprogramming and uncovers reprogramming barriers.

Gallego-Perez D, Otero JJ, Czeisler C, Ma J, Ortiz C, Gygli P, Catacutan FP, Gokozan HN, Cowgill A, Sherwood T, Ghatak S, Malkoc V, Zhao X, Liao WC, Gnyawali S, Wang X, Adler AF, Leong K, Wulff B, Wilgus TA, Askwith C, Khanna S, Rink C, Sen CK, Lee LJ.

Nanomedicine. 2016 Feb;12(2):399-409. doi: 10.1016/j.nano.2015.11.015. Epub 2015 Dec 19.


High risk of near-crash driving events following night-shift work.

Lee ML, Howard ME, Horrey WJ, Liang Y, Anderson C, Shreeve MS, O'Brien CS, Czeisler CA.

Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):176-81. doi: 10.1073/pnas.1510383112. Epub 2015 Dec 22.


Sleep Duration and Disruption and Prostate Cancer Risk: a 23-Year Prospective Study.

Markt SC, Flynn-Evans EE, Valdimarsdottir UA, Sigurdardottir LG, Tamimi RM, Batista JL, Haneuse S, Lockley SW, Stampfer M, Wilson KM, Czeisler CA, Rider JR, Mucci LA.

Cancer Epidemiol Biomarkers Prev. 2016 Feb;25(2):302-8. doi: 10.1158/1055-9965.EPI-14-1274. Epub 2015 Dec 16.


Impact of Sleep and Circadian Disruption on Energy Balance and Diabetes: A Summary of Workshop Discussions.

Arble DM, Bass J, Behn CD, Butler MP, Challet E, Czeisler C, Depner CM, Elmquist J, Franken P, Grandner MA, Hanlon EC, Keene AC, Joyner MJ, Karatsoreos I, Kern PA, Klein S, Morris CJ, Pack AI, Panda S, Ptacek LJ, Punjabi NM, Sassone-Corsi P, Scheer FA, Saxena R, Seaquest ER, Thimgan MS, Van Cauter E, Wright KP.

Sleep. 2015 Dec 1;38(12):1849-60. doi: 10.5665/sleep.5226.

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