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Items: 26


Genomic Landscape Survey Identifies SRSF1 as a Key Oncodriver in Small Cell Lung Cancer.

Jiang L, Huang J, Higgs BW, Hu Z, Xiao Z, Yao X, Conley S, Zhong H, Liu Z, Brohawn P, Shen D, Wu S, Ge X, Jiang Y, Zhao Y, Lou Y, Morehouse C, Zhu W, Sebastian Y, Czapiga M, Oganesyan V, Fu H, Niu Y, Zhang W, Streicher K, Tice D, Zhao H, Zhu M, Xu L, Herbst R, Su X, Gu Y, Li S, Huang L, Gu J, Han B, Jallal B, Shen H, Yao Y.

PLoS Genet. 2016 Apr 19;12(4):e1005895. doi: 10.1371/journal.pgen.1005895. eCollection 2016 Apr.


Resolution of Skin Fibrosis by Neutralization of the Antifibrinolytic Function of Plasminogen Activator Inhibitor 1.

Lemaire R, Burwell T, Sun H, Delaney T, Bakken J, Cheng L, Rebelatto MC, Czapiga M, de-Mendez I, Coyle AJ, Herbst R, Lafyatis R, Connor J.

Arthritis Rheumatol. 2016 Feb;68(2):473-83. doi: 10.1002/art.39443.


S100A9 induced inflammatory responses are mediated by distinct damage associated molecular patterns (DAMP) receptors in vitro and in vivo.

Chen B, Miller AL, Rebelatto M, Brewah Y, Rowe DC, Clarke L, Czapiga M, Rosenthal K, Imamichi T, Chen Y, Chang CS, Chowdhury PS, Naiman B, Wang Y, Yang D, Humbles AA, Herbst R, Sims GP.

PLoS One. 2015 Feb 23;10(2):e0115828. doi: 10.1371/journal.pone.0115828. eCollection 2015.


Inhibition of myogenic microRNAs 1, 133, and 206 by inflammatory cytokines links inflammation and muscle degeneration in adult inflammatory myopathies.

Georgantas RW, Streicher K, Greenberg SA, Greenlees LM, Zhu W, Brohawn PZ, Higgs BW, Czapiga M, Morehouse CA, Amato A, Richman L, Jallal B, Yao Y, Ranade K.

Arthritis Rheumatol. 2014 Apr;66(4):1022-33. doi: 10.1002/art.38292.


Low frequency KRAS mutations in colorectal cancer patients and the presence of multiple mutations in oncogenic drivers in non-small cell lung cancer patients.

Jiang L, Huang J, Morehouse C, Zhu W, Korolevich S, Sui D, Ge X, Lehmann K, Liu Z, Kiefer C, Czapiga M, Su X, Brohawn P, Gu Y, Higgs BW, Yao Y.

Cancer Genet. 2013 Sep-Oct;206(9-10):330-9. doi: 10.1016/j.cancergen.2013.09.004. Epub 2013 Oct 2.


MEDI3617, a human anti-angiopoietin 2 monoclonal antibody, inhibits angiogenesis and tumor growth in human tumor xenograft models.

Leow CC, Coffman K, Inigo I, Breen S, Czapiga M, Soukharev S, Gingles N, Peterson N, Fazenbaker C, Woods R, Jallal B, Ricketts SA, Lavallee T, Coats S, Chang Y.

Int J Oncol. 2012 May;40(5):1321-30. doi: 10.3892/ijo.2012.1366. Epub 2012 Feb 10.


Innate immunity against Granulibacter bethesdensis, an emerging gram-negative bacterial pathogen.

Zarember KA, Marshall-Batty KR, Cruz AR, Chu J, Fenster ME, Shoffner AR, Rogge LS, Whitney AR, Czapiga M, Song HH, Shaw PA, Nagashima K, Malech HL, DeLeo FR, Holland SM, Gallin JI, Greenberg DE.

Infect Immun. 2012 Mar;80(3):975-81. doi: 10.1128/IAI.05557-11. Epub 2011 Dec 19.


Altered expression of insulin receptor isoforms in breast cancer.

Huang J, Morehouse C, Streicher K, Higgs BW, Gao J, Czapiga M, Boutrin A, Zhu W, Brohawn P, Chang Y, Viner J, LaVallee T, Richman L, Jallal B, Yao Y.

PLoS One. 2011;6(10):e26177. doi: 10.1371/journal.pone.0026177. Epub 2011 Oct 26.


Virulence and cellular interactions of Burkholderia multivorans in chronic granulomatous disease.

Zelazny AM, Ding L, Elloumi HZ, Brinster LR, Benedetti F, Czapiga M, Ulrich RL, Ballentine SJ, Goldberg JB, Sampaio EP, Holland SM.

Infect Immun. 2009 Oct;77(10):4337-44. doi: 10.1128/IAI.00259-09. Epub 2009 Jul 27.


Functionally competent eosinophils differentiated ex vivo in high purity from normal mouse bone marrow.

Dyer KD, Moser JM, Czapiga M, Siegel SJ, Percopo CM, Rosenberg HF.

J Immunol. 2008 Sep 15;181(6):4004-9.


Detection and imaging of non-contractile inclusions and sarcomeric anomalies in skeletal muscle by second harmonic generation combined with two-photon excited fluorescence.

Ralston E, Swaim B, Czapiga M, Hwu WL, Chien YH, Pittis MG, Bembi B, Schwartz O, Plotz P, Raben N.

J Struct Biol. 2008 Jun;162(3):500-8. doi: 10.1016/j.jsb.2008.03.010. Epub 2008 Apr 8.


Pneumocystis encodes a functional S-adenosylmethionine synthetase gene.

Kutty G, Hernandez-Novoa B, Czapiga M, Kovacs JA.

Eukaryot Cell. 2008 Feb;7(2):258-67. Epub 2007 Dec 7.


Photoconversion of Lysotracker Red to a green fluorescent molecule.

Freundt EC, Czapiga M, Lenardo MJ.

Cell Res. 2007 Nov;17(11):956-8. No abstract available.


Eosinophils from lineage-ablated Delta dblGATA bone marrow progenitors: the dblGATA enhancer in the promoter of GATA-1 is not essential for differentiation ex vivo.

Dyer KD, Czapiga M, Foster B, Foster PS, Kang EM, Lappas CM, Moser JM, Naumann N, Percopo CM, Siegel SJ, Swartz JM, Ting-De Ravin S, Rosenberg HF.

J Immunol. 2007 Aug 1;179(3):1693-9.


Unique pathology in simian immunodeficiency virus-infected rapid progressor macaques is consistent with a pathogenesis distinct from that of classical AIDS.

Brown CR, Czapiga M, Kabat J, Dang Q, Ourmanov I, Nishimura Y, Martin MA, Hirsch VM.

J Virol. 2007 Jun;81(11):5594-606. Epub 2007 Mar 21.


Evolution and function of leukocyte RNase A ribonucleases of the avian species, Gallus gallus.

Nitto T, Dyer KD, Czapiga M, Rosenberg HF.

J Biol Chem. 2006 Sep 1;281(35):25622-34. Epub 2006 Jun 27.


Human platelets exhibit chemotaxis using functional N-formyl peptide receptors.

Czapiga M, Gao JL, Kirk A, Lekstrom-Himes J.

Exp Hematol. 2005 Jan;33(1):73-84.


Microglial function in human APOE3 and APOE4 transgenic mice: altered arginine transport.

Czapiga M, Colton CA.

J Neuroimmunol. 2003 Jan;134(1-2):44-51.


APOE and the regulation of microglial nitric oxide production: a link between genetic risk and oxidative stress.

Colton CA, Brown CM, Cook D, Needham LK, Xu Q, Czapiga M, Saunders AM, Schmechel DE, Rasheed K, Vitek MP.

Neurobiol Aging. 2002 Sep-Oct;23(5):777-85.


Apolipoprotein-E allele-specific regulation of nitric oxide production.

Colton CA, Brown CM, Czapiga M, Vitek MP.

Ann N Y Acad Sci. 2002 May;962:212-25. Review.


Apolipoprotein E acts to increase nitric oxide production in macrophages by stimulating arginine transport.

Colton CA, Czapiga M, Snell-Callanan J, Chernyshev ON, Vitek MP.

Biochim Biophys Acta. 2001 Feb 14;1535(2):134-44.


Function of microglia in organotypic slice cultures.

Czapiga M, Colton CA.

J Neurosci Res. 1999 Jun 15;56(6):644-51.


The effects of the naltrexone implant on rodent social interactions and cocaine-induced conditioned place preference.

Mitchem LD, Kruschel CK, Dallman E, Anders KA, Czapiga M, Panos JJ, Steinpreis RE.

Pharmacol Biochem Behav. 1999 Jan;62(1):97-102.


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