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Items: 1 to 50 of 68


Interplay between the bacterial protein deacetylase CobB and the second messenger c-di-GMP.

Xu Z, Zhang H, Zhang X, Jiang H, Liu C, Wu F, Qian L, Hao B, Czajkowsky DM, Guo S, Xu Z, Bi L, Wang S, Li H, Tan M, Yan W, Feng L, Hou J, Tao SC.

EMBO J. 2019 Aug 16:e100948. doi: 10.15252/embj.2018100948. [Epub ahead of print]


Evidence for heightened genetic instability in precancerous spasmolytic polypeptide expressing gastric glands.

Chen J, Zhu C, Wang C, Hu C, Czajkowsky DM, Guo Y, Liu B, Shao Z.

J Med Genet. 2019 Mar 15. pii: jmedgenet-2018-105752. doi: 10.1136/jmedgenet-2018-105752. [Epub ahead of print]


Discovery and genetic characterization of intestinal metaplasia in the Helicobacter felis-infected mouse model of gastric cancer.

Chen J, Zhu C, Wang C, Zhang X, Ni J, Czajkowsky DM, Liu B, Guo Y.

Acta Biochim Biophys Sin (Shanghai). 2019 Feb 1;51(2):219-222. doi: 10.1093/abbs/gmy160. No abstract available.


abLIM1 constructs non-erythroid cortical actin networks to prevent mechanical tension-induced blebbing.

Li G, Huang S, Yang S, Wang J, Cao J, Czajkowsky DM, Shao Z, Zhu X.

Cell Discov. 2018 Jul 24;4:42. doi: 10.1038/s41421-018-0040-3. eCollection 2018.


Helix α-3 inter-molecular salt bridges and conformational changes are essential for toxicity of Bacillus thuringiensis 3D-Cry toxin family.

Pacheco S, Gómez I, Sánchez J, García-Gómez BI, Czajkowsky DM, Zhang J, Soberón M, Bravo A.

Sci Rep. 2018 Jul 9;8(1):10331. doi: 10.1038/s41598-018-28753-8.


Cell Lysate Microarray for Mapping the Network of Genetic Regulators for Histone Marks.

Cheng L, Liu CX, Jiang S, Hou S, Huang JG, Chen ZQ, Sun YY, Qi H, Jiang HW, Wang JF, Zhou YM, Czajkowsky DM, Dai J, Tao SC.

Mol Cell Proteomics. 2018 Sep;17(9):1720-1736. doi: 10.1074/mcp.RA117.000550. Epub 2018 Jun 5.


Super-resolution Imaging of Individual Human Subchromosomal Regions in Situ Reveals Nanoscopic Building Blocks of Higher-Order Structure.

Fang K, Chen X, Li X, Shen Y, Sun J, Czajkowsky DM, Shao Z.

ACS Nano. 2018 May 22;12(5):4909-4918. doi: 10.1021/acsnano.8b01963. Epub 2018 May 4.


Identification of Serine 119 as an Effective Inhibitor Binding Site of M. tuberculosis Ubiquitin-like Protein Ligase PafA Using Purified Proteins and M. smegmatis.

Jiang HW, Czajkowsky DM, Wang T, Wang XD, Wang JB, Zhang HN, Liu CX, Wu FL, He X, Xu ZW, Chen H, Guo SJ, Li Y, Bi LJ, Deng JY, Xie J, Pei JF, Zhang XE, Tao SC.

EBioMedicine. 2018 Apr;30:225-236. doi: 10.1016/j.ebiom.2018.03.025. Epub 2018 Mar 27.


Compressive Force Spectroscopy: From Living Cells to Single Proteins.

Wang J, Liu M, Shen Y, Sun J, Shao Z, Czajkowsky DM.

Int J Mol Sci. 2018 Mar 23;19(4). pii: E960. doi: 10.3390/ijms19040960. Review.


Sub-kb Hi-C in D. melanogaster reveals conserved characteristics of TADs between insect and mammalian cells.

Wang Q, Sun Q, Czajkowsky DM, Shao Z.

Nat Commun. 2018 Jan 15;9(1):188. doi: 10.1038/s41467-017-02526-9.


The Ser/Thr Protein Kinase Protein-Protein Interaction Map of M. tuberculosis.

Wu FL, Liu Y, Jiang HW, Luan YZ, Zhang HN, He X, Xu ZW, Hou JL, Ji LY, Xie Z, Czajkowsky DM, Yan W, Deng JY, Bi LJ, Zhang XE, Tao SC.

Mol Cell Proteomics. 2017 Aug;16(8):1491-1506. doi: 10.1074/mcp.M116.065771. Epub 2017 Jun 1.


Toward the development of magnetic tweezers for high-throughput measurement of protein-protein interactions.

Cao H, Shen Y, Sun Y, Tao SC, Czajkowsky DM, Shao Z.

Acta Biochim Biophys Sin (Shanghai). 2017 May 1;49(5):468-470. doi: 10.1093/abbs/gmx027. No abstract available.


Improved clearing of lipid droplet-rich tissues for three-dimensional structural elucidation.

Lai M, Li X, Li J, Hu Y, Czajkowsky DM, Shao Z.

Acta Biochim Biophys Sin (Shanghai). 2017 May 1;49(5):465-467. doi: 10.1093/abbs/gmx018. No abstract available.


Glycan-independent binding and internalization of human IgM to FCMR, its cognate cellular receptor.

Lloyd KA, Wang J, Urban BC, Czajkowsky DM, Pleass RJ.

Sci Rep. 2017 Feb 23;7:42989. doi: 10.1038/srep42989.


Rapid Production of Virus Protein Microarray Using Protein Microarray Fabrication through Gene Synthesis (PAGES).

Qi H, Zhou H, Czajkowsky DM, Guo S, Li Y, Wang N, Shi Y, Lin L, Wang J, Wu, Tao SC.

Mol Cell Proteomics. 2017 Feb;16(2):288-299. doi: 10.1074/mcp.M116.064873. Epub 2016 Dec 13.


Ultra-deep sequencing of ribosome-associated poly-adenylated RNA in early Drosophila embryos reveals hundreds of conserved translated sORFs.

Li H, Hu C, Bai L, Li H, Li M, Zhao X, Czajkowsky DM, Shao Z.

DNA Res. 2016 Dec;23(6):571-580. Epub 2016 Aug 24.


Nanoscopic characterization of the water vapor-salt interfacial layer reveals a unique biphasic adsorption process.

Yang L, He J, Shen Y, Li X, Sun J, Czajkowsky DM, Shao Z.

Sci Rep. 2016 Aug 16;6:31688. doi: 10.1038/srep31688.


Development of a low-noise cryogenic atomic force microscope for high resolution imaging of large biological complexes.

Qin L, Zhang J, Sun J, Czajkowsky DM, Shao Z.

Acta Biochim Biophys Sin (Shanghai). 2016 Sep;48(9):859-61. doi: 10.1093/abbs/gmw074. Epub 2016 Aug 12. No abstract available.


Complex clonal mosaicism within microdissected intestinal metaplastic glands without concurrent gastric cancer.

Guo Y, Huang A, Hu C, Zhou Y, Zhang X, Czajkowsky DM, Li J, Cheng S, Shen R, Gu J, Liu B, Shao Z.

J Med Genet. 2016 Sep;53(9):643-6. doi: 10.1136/jmedgenet-2016-103872. Epub 2016 Jun 9.


The non-coding RNA composition of the mitotic chromosome by 5'-tag sequencing.

Meng Y, Yi X, Li X, Hu C, Wang J, Bai L, Czajkowsky DM, Shao Z.

Nucleic Acids Res. 2016 Jun 2;44(10):4934-46. doi: 10.1093/nar/gkw195. Epub 2016 Mar 25.


YcgC represents a new protein deacetylase family in prokaryotes.

Tu S, Guo SJ, Chen CS, Liu CX, Jiang HW, Ge F, Deng JY, Zhou YM, Czajkowsky DM, Li Y, Qi BR, Ahn YH, Cole PA, Zhu H, Tao SC.

Elife. 2015 Dec 30;4. pii: e05322. doi: 10.7554/eLife.05322.


Single molecule compression reveals intra-protein forces drive cytotoxin pore formation.

Czajkowsky DM, Sun J, Shao Z.

Elife. 2015 Dec 10;4:e08421. doi: 10.7554/eLife.08421.


Systematic identification of arsenic-binding proteins reveals that hexokinase-2 is inhibited by arsenic.

Zhang HN, Yang L, Ling JY, Czajkowsky DM, Wang JF, Zhang XW, Zhou YM, Ge F, Yang MK, Xiong Q, Guo SJ, Le HY, Wu SF, Yan W, Liu B, Zhu H, Chen Z, Tao SC.

Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15084-9. doi: 10.1073/pnas.1521316112. Epub 2015 Nov 23.


Single molecule atomic force microscopy of aerolysin pore complexes reveals unexpected star-shaped topography.

He J, Wang J, Hu J, Sun J, Czajkowsky DM, Shao Z.

J Mol Recognit. 2016 Apr;29(4):174-81. doi: 10.1002/jmr.2517. Epub 2015 Nov 5.


Single-cell codetection of metabolic activity, intracellular functional proteins, and genetic mutations from rare circulating tumor cells.

Zhang Y, Tang Y, Sun S, Wang Z, Wu W, Zhao X, Czajkowsky DM, Li Y, Tian J, Xu L, Wei W, Deng Y, Shi Q.

Anal Chem. 2015 Oct 6;87(19):9761-8. doi: 10.1021/acs.analchem.5b01901.


Identification of the minimal binding region of a Plasmodium falciparum IgM binding PfEMP1 domain.

Semblat JP, Ghumra A, Czajkowsky DM, Wallis R, Mitchell DA, Raza A, Rowe JA.

Mol Biochem Parasitol. 2015 May;201(1):76-82. doi: 10.1016/j.molbiopara.2015.06.001. Epub 2015 Jun 18.


Fast immuno-labeling by electrophoretically driven infiltration for intact tissue imaging.

Li J, Czajkowsky DM, Li X, Shao Z.

Sci Rep. 2015 May 27;5:10640. doi: 10.1038/srep10640.


Developing the IVIG biomimetic, hexa-Fc, for drug and vaccine applications.

Czajkowsky DM, Andersen JT, Fuchs A, Wilson TJ, Mekhaiel D, Colonna M, He J, Shao Z, Mitchell DA, Wu G, Dell A, Haslam S, Lloyd KA, Moore SC, Sandlie I, Blundell PA, Pleass RJ.

Sci Rep. 2015 Apr 27;5:9526. doi: 10.1038/srep09526.


Lectin RCA-I specifically binds to metastasis-associated cell surface glycans in triple-negative breast cancer.

Zhou SM, Cheng L, Guo SJ, Wang Y, Czajkowsky DM, Gao H, Hu XF, Tao SC.

Breast Cancer Res. 2015 Mar 11;17:36. doi: 10.1186/s13058-015-0544-9.


An integrated microfluidic chip system for single-cell secretion profiling of rare circulating tumor cells.

Deng Y, Zhang Y, Sun S, Wang Z, Wang M, Yu B, Czajkowsky DM, Liu B, Li Y, Wei W, Shi Q.

Sci Rep. 2014 Dec 16;4:7499. doi: 10.1038/srep07499.


Illuminated up close: near-field optical microscopy of cell surfaces.

Czajkowsky DM, Sun J, Shao Z.

Nanomedicine. 2015 Jan;11(1):119-25. doi: 10.1016/j.nano.2014.08.002. Epub 2014 Aug 23.


Genome-wide profiling of untranslated regions by paired-end ditag sequencing reveals unexpected transcriptome complexity in yeast.

Kang YN, Lai DP, Ooi HS, Shen TT, Kou Y, Tian J, Czajkowsky DM, Shao Z, Zhao X.

Mol Genet Genomics. 2015 Feb;290(1):217-24. doi: 10.1007/s00438-014-0913-6. Epub 2014 Sep 12.


Anomalous surface fatigue in a nano-layered material.

Yang L, Czajkowsky DM, Sun J, Hu J, Shao Z.

Adv Mater. 2014 Oct 8;26(37):6478-82. doi: 10.1002/adma.201401906. Epub 2014 Aug 28.


Molecular threading and tunable molecular recognition on DNA origami nanostructures.

Wu N, Czajkowsky DM, Zhang J, Qu J, Ye M, Zeng D, Zhou X, Hu J, Shao Z, Li B, Fan C.

J Am Chem Soc. 2013 Aug 21;135(33):12172-5. doi: 10.1021/ja403863a. Epub 2013 Aug 7.


A novel electromagnetic apparatus for rapid multiplex single molecule force spectroscopy.

Shen Y, Czajkowsky DM, Li X, Sun J, Hu J, Shao Z.

J Nanosci Nanotechnol. 2013 Feb;13(2):1232-6.


Fc-fusion proteins: new developments and future perspectives.

Czajkowsky DM, Hu J, Shao Z, Pleass RJ.

EMBO Mol Med. 2012 Oct;4(10):1015-28. doi: 10.1002/emmm.201201379. Epub 2012 Jul 26. Review.


Self-assembling subnanometer pores with unusual mass-transport properties.

Zhou X, Liu G, Yamato K, Shen Y, Cheng R, Wei X, Bai W, Gao Y, Li H, Liu Y, Liu F, Czajkowsky DM, Wang J, Dabney MJ, Cai Z, Hu J, Bright FV, He L, Zeng XC, Shao Z, Gong B.

Nat Commun. 2012 Jul 17;3:949. doi: 10.1038/ncomms1949.


Microdissection of spatially identified single nuclei in a solid tumor for single cell whole genome sequencing.

Guo Y, Yang Y, Zhou J, Czajkowsky DM, Liu B, Shao Z.

Biotechniques. 2012 Apr 1;52(4). doi: 10.2144/000113860.


Polymeric human Fc-fusion proteins with modified effector functions.

Mekhaiel DN, Czajkowsky DM, Andersen JT, Shi J, El-Faham M, Doenhoff M, McIntosh RS, Sandlie I, He J, Hu J, Shao Z, Pleass RJ.

Sci Rep. 2011;1:124. doi: 10.1038/srep00124. Epub 2011 Oct 19.


Heteroepitaxial streptavidin nanocrystals reveal critical role of proton "fingers" and subsurface atoms in determining adsorbed protein orientation.

Czajkowsky DM, Li L, Sun J, Hu J, Shao Z.

ACS Nano. 2012 Jan 24;6(1):190-8. doi: 10.1021/nn203356p. Epub 2011 Dec 21.


In situ monitoring of single molecule binding reactions with time-lapse atomic force microscopy on functionalized DNA origami.

Wu N, Zhou X, Czajkowsky DM, Ye M, Zeng D, Fu Y, Fan C, Hu J, Li B.

Nanoscale. 2011 Jun;3(6):2481-4. doi: 10.1039/c1nr10181a. Epub 2011 Apr 28.


IgM, Fc mu Rs, and malarial immune evasion.

Czajkowsky DM, Salanti A, Ditlev SB, Shao Z, Ghumra A, Rowe JA, Pleass RJ.

J Immunol. 2010 May 1;184(9):4597-603. doi: 10.4049/jimmunol.1000203. Review.


The human IgM pentamer is a mushroom-shaped molecule with a flexural bias.

Czajkowsky DM, Shao Z.

Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14960-5. doi: 10.1073/pnas.0903805106. Epub 2009 Aug 17.


Measurement of the electron-phonon coupling factor dependence on film thickness and grain size in Au, Cr, and Al.

Hostetler JL, Smith AN, Czajkowsky DM, Norris PM.

Appl Opt. 1999 Jun 1;38(16):3614-20.


Cell cycle-dependent nucleosome occupancy at cohesin binding sites in yeast chromosomes.

Liu J, Czajkowsky DM, Liang S, Shao Z.

Genomics. 2008 Mar;91(3):274-80. doi: 10.1016/j.ygeno.2007.11.006.


DNA combing reveals intrinsic temporal disorder in the replication of yeast chromosome VI.

Czajkowsky DM, Liu J, Hamlin JL, Shao Z.

J Mol Biol. 2008 Jan 4;375(1):12-9. Epub 2007 Oct 23. Review.


Random mutagenesis of Helicobacter pylori vacA to identify amino acids essential for vacuolating cytotoxic activity.

McClain MS, Czajkowsky DM, Torres VJ, Szabo G, Shao Z, Cover TL.

Infect Immun. 2006 Nov;74(11):6188-95. Epub 2006 Sep 5.


Localization of linker histone in chromatosomes by cryo-atomic force microscopy.

Sheng S, Czajkowsky DM, Shao Z.

Biophys J. 2006 Aug 15;91(4):L35-7. Epub 2006 Jun 16.


Mimicry of a host anion channel by a Helicobacter pylori pore-forming toxin.

Czajkowsky DM, Iwamoto H, Szabo G, Cover TL, Shao Z.

Biophys J. 2005 Nov;89(5):3093-101. Epub 2005 Aug 12.


Vertical collapse of a cytolysin prepore moves its transmembrane beta-hairpins to the membrane.

Czajkowsky DM, Hotze EM, Shao Z, Tweten RK.

EMBO J. 2004 Aug 18;23(16):3206-15. Epub 2004 Aug 5.

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