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Items: 1 to 50 of 74

1.

Reaction of geldanamycin and C17-substituted analogues with glutathione: product identifications and pharmacological implications.

Cysyk RL, Parker RJ, Barchi JJ Jr, Steeg PS, Hartman NR, Strong JM.

Chem Res Toxicol. 2006 Mar;19(3):376-81.

PMID:
16544941
2.

Zebularine metabolism by aldehyde oxidase in hepatic cytosol from humans, monkeys, dogs, rats, and mice: influence of sex and inhibitors.

Klecker RW, Cysyk RL, Collins JM.

Bioorg Med Chem. 2006 Jan 1;14(1):62-6. Epub 2005 Sep 6.

PMID:
16143537
3.

Production of intracellular 35S-glutathione by rat and human hepatocytes for the quantification of xenobiotic reactive intermediates.

Hartman NR, Cysyk RL, Bruneau-Wack C, Thénot JP, Parker RJ, Strong JM.

Chem Biol Interact. 2002 Nov 10;142(1-2):43-55.

PMID:
12399154
5.

Tiazofurin enhances the anabolism and toxicity of 5-fluorouracil.

Cysyk RL, Chisena CA, Hyman R, Monks A.

Cancer Lett. 1996 Dec 3;109(1-2):49-55.

PMID:
9020902
6.

Synthesis and release of hyaluronic acid by Swiss 3T3 fibroblasts.

Kitchen JR, Cysyk RL.

Biochem J. 1995 Jul 15;309 ( Pt 2):649-56.

7.

A filter paper assay for hyaluronic acid synthetase: application to the enzyme from Swiss 3T3 fibroblasts.

Malinowski NM, Cysyk RL, August EM.

Biochem Mol Biol Int. 1995 Apr;35(5):1123-32.

PMID:
7549931
8.

Cyclopentenyl uracil: an effective inhibitor of uridine salvage in vivo.

Cysyk RL, Malinowski N, Marquez V, Zaharevitz D, August EM, Moyer JD.

Biochem Pharmacol. 1995 Jan 18;49(2):203-7.

PMID:
7840797
9.
10.

Vanadate inhibition of hyaluronic acid synthesis in Swiss 3T3 fibroblasts.

Zaharevitz DW, Chisena CA, Duncan KL, August EM, Cysyk RL.

Biochem Mol Biol Int. 1993 Nov;31(4):627-33.

PMID:
7507761
11.

Serum stimulation of UDP-glucose dehydrogenase activity in Swiss 3T3 fibroblasts.

Grubb MF, Kasofsky J, Strong J, Anderson LW, Cysyk RL.

Biochem Mol Biol Int. 1993 Aug;30(5):819-27.

PMID:
8220234
12.

Effect of high-protein diet on pyrimidine synthesis and response to PALA in mouse tissues.

Zaharevitz DW, Grubb MF, Hyman R, Chisena C, Cysyk RL.

J Natl Cancer Inst. 1993 Apr 21;85(8):662-6.

PMID:
8468725
13.

Inhibition of fibroblast hyaluronic acid production by suramin.

August EM, Duncan KL, Malinowski NM, Cysyk RL.

Oncol Res. 1993;5(10-11):415-22.

PMID:
8054702
14.

Contribution of de-novo and salvage synthesis to the uracil nucleotide pool in mouse tissues and tumors in vivo.

Zaharevitz DW, Anderson LW, Malinowski NM, Hyman R, Strong JM, Cysyk RL.

Eur J Biochem. 1992 Nov 15;210(1):293-6.

15.

De novo synthesis of uracil nucleotides in mouse liver and intestine studied using [15N]alanine.

Zaharevitz DW, Anderson LW, Strong JM, Hyman R, Cysyk RL.

Eur J Biochem. 1990 Apr 30;189(2):437-40.

16.

Rapid increase of cellular UDP-glucuronide after mitogen stimulation of quiescent 3T3 mouse fibroblasts.

Zaharevitz DW, Chisena CA, Cysyk RL.

Biochem Int. 1990;20(6):1067-76.

PMID:
2196057
17.

Cellular pharmacology of DUP-785, a new anticancer agent.

Anderson LW, Strong JM, Cysyk RL.

Cancer Commun. 1989;1(6):381-7.

PMID:
2562006
18.

Stimulation of uracil nucleotide synthesis in mouse liver, intestine and kidney by ammonium chloride infusion.

Zaharevitz DW, Napier EA, Anderson LW, Strong JM, Cysyk RL.

Eur J Biochem. 1988 Jul 15;175(1):193-8.

19.

Attempts to increase intratumoral blood flow in the rat solid Walker 256 tumor by the use of the perfluorocarbon emulsion fluosol-DA.

Klubes P, Hiraga S, Cysyk RL, Owens ES, Blasberg RG.

Eur J Cancer Clin Oncol. 1987 Dec;23(12):1859-67.

PMID:
3436350
20.

Increases in brain tumor and cerebral blood flow by blood-perfluorochemical emulsion (Fluosol-DA) exchange.

Hiraga S, Klubes P, Owens ES, Cysyk RL, Blasberg RG.

Cancer Res. 1987 Jun 15;47(12):3296-302.

22.

Adenosine export from the liver: oxygen dependency.

Arnold ST, Cysyk RL.

Am J Physiol. 1986 Jul;251(1 Pt 1):G34-9.

PMID:
3728675
23.

The effect of 3-deazauridine and dipyridamole on uridine utilization by mice.

Moyer JD, Malinowski N, Cysyk RL.

Eur J Cancer Clin Oncol. 1986 Mar;22(3):323-7.

PMID:
2423341
24.

Comparison of the bioavailability of uridine in mice after either oral or parenteral administration.

Klubes P, Geffen DB, Cysyk RL.

Cancer Chemother Pharmacol. 1986;17(3):236-40.

PMID:
3742709
25.

Inhibition of uridine kinase and the salvage of uridine by modified pyrimidine nucleosides.

Moyer JD, Karle JM, Malinowski N, Marquez VE, Salam MA, Malspeis L, Cysyk RL.

Mol Pharmacol. 1985 Nov;28(5):454-60.

PMID:
2997596
26.
27.

A novel approach to the analysis of mass spectrally assayed stable isotope-labeling experiments.

Strong JM, Upton DK, Anderson LW, Monks A, Chisena CA, Cysyk RL.

J Biol Chem. 1985 Apr 10;260(7):4276-81.

28.

Influence of ammonium ions on hepatic de novo pyrimidine biosynthesis.

Monks A, Chisena CA, Cysyk RL.

Arch Biochem Biophys. 1985 Jan;236(1):1-10.

PMID:
2981502
29.

Regulation of pyrimidine biosynthesis in cultured L1210 cells by 3-deazauridine.

Karle JM, Cysyk RL.

Biochem Pharmacol. 1984 Dec 1;33(23):3739-42.

PMID:
6095859
30.

Effect of 2-beta-D-ribofuranosylthiazole-4-carboxamide on uptake of nucleosides by cultured L1210 cells.

Karle JM, Monks A, Wolfe RM, Cysyk RL.

Cancer Lett. 1984 Aug;24(1):11-8.

PMID:
6498794
31.

Metabolism of 4'-(9-acridinylamino)methanesulfon-m-anisidide by rat liver microsomes.

Shoemaker DD, Cysyk RL, Gormley PE, DeSouza JJ, Malspeis L.

Cancer Res. 1984 May;44(5):1939-45.

32.

Effect of plasma concentrations of uridine on pyrimidine biosynthesis in cultured L1210 cells.

Karle JM, Anderson LW, Cysyk RL.

J Biol Chem. 1984 Jan 10;259(1):67-72.

33.
34.

A 13C tracer method for quantitating de novo pyrimidine biosynthesis in vitro and in vivo.

Strong JM, Anderson LW, Monks A, Chisena CA, Cysyk RL.

Anal Biochem. 1983 Jul 15;132(2):243-53.

PMID:
6414331
35.
36.
37.

Uridine regulation by the isolated rat liver: perfusion with an artificial oxygen carrier.

Monks A, Cysyk RL.

Am J Physiol. 1982 May;242(5):R465-70.

PMID:
7081472
38.

Identification of the principal biliary metabolite of 4'-(9-acridinylamino)methanesulfon-m-anisidide in rats.

Shoemaker DD, Cysyk RL, Padmanabhan S, Bhat HB, Malspeis L.

Drug Metab Dispos. 1982 Jan-Feb;10(1):35-9.

PMID:
6124380
39.

Effect of inhibitors of the de novo pyrimidine biosynthetic pathway on serum uridine levels in mice.

Karle JM, Anderson LW, Dietrick DD, Cysyk RL.

Cancer Res. 1981 Dec;41(12 Pt 1):4952-5.

40.

Absorption of m-AMSA and its biliary metabolites from the rat small intestine.

Gormley PE, Shoemaker D, Rozencweig M, Ayers OC, Cysyk RL.

Eur J Cancer Clin Oncol. 1981 Oct;17(10):1143-6. No abstract available.

PMID:
6896029
41.
42.

Induction and development of mouse liver glutathione S-transferase activity.

Shoemaker DD, Dietrick DD, Cysyk RL.

Experientia. 1981 May 15;37(5):445-6.

PMID:
7250306
43.

Studies on the disposition of 2,3-dihydro-1 H-imidazo[1,2-b] pyrazole in rodents.

Shoemaker DD, Ayers OC, D'Anna ME, Cysyk RL.

Eur J Cancer. 1981 Apr;17(4):391-6. No abstract available.

PMID:
7308252
44.

Mechanism of action of N2-substituted spin labeled actinomycin D: binding to nucleic acids and erythrocyte ghost membranes.

Sinha BK, Cysyk RL.

Chem Biol Interact. 1981 Mar 15;34(3):367-72. No abstract available.

PMID:
6257409
45.

Mechanism of resistance of variants of the Lewis lung carcinoma to N-(phosphonacetyl)-L-aspartic acid.

Kensler TW, Mutter G, Hankerson JG, Reck LJ, Harley C, Han N, Ardalan B, Cysyk RL, Johnson RK, Jayaram HN, Cooney DA.

Cancer Res. 1981 Mar;41(3):894-904.

46.

Determination of serum and plasma uridine levels in mice, rats, and humans by high-pressure liquid chromatography.

Karle JM, Anderson LW, Dietrick DD, Cysyk RL.

Anal Biochem. 1980 Nov 15;109(1):41-6. No abstract available.

PMID:
7469017
47.
48.

Serum uridine levels in patients receiving N-(phosphonacetyl)-L-aspartate.

Karle JM, Anderson LW, Erlichman C, Cysyk RL.

Cancer Res. 1980 Aug;40(8 Pt 1):2938-40.

49.

Treatment of solid L1210 murine tumors with local hyperthermia and temperature-sensitive liposomes containing methotrexate.

Weinstein JN, Magin RL, Cysyk RL, Zaharko DS.

Cancer Res. 1980 May;40(5):1388-95. No abstract available.

50.

Distribution of adriamycin in mice under conditions of local hyperthermia which improve systemic drug therapy.

Magin RL, Cysyk RL, Litterst CL.

Cancer Treat Rep. 1980 Feb-Mar;64(2-3):203-10.

PMID:
7407753

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