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Items: 1 to 50 of 501

1.

Versatile and robust genome editing with Streptococcus thermophilus CRISPR1-Cas9.

Agudelo D, Carter S, Velimirovic M, Duringer A, Rivest JF, Levesque S, Loehr J, Mouchiroud M, Cyr D, Waters PJ, Laplante M, Moineau S, Goulet A, Doyon Y.

Genome Res. 2020 Jan;30(1):107-117. doi: 10.1101/gr.255414.119. Epub 2020 Jan 3.

PMID:
31900288
2.

Biological Characterization of F508delCFTR Protein Processing by the CFTR Corrector ABBV-2222/GLPG2222.

Singh AK, Fan Y, Balut C, Alani S, Manelli AM, Swensen AM, Jia Y, Neelands TR, Vortherms TA, Liu B, Searle XB, Wang X, Gao W, Hwang TC, Ren HY, Cyr D, Kym PR, Conrath K, Tse C.

J Pharmacol Exp Ther. 2020 Jan;372(1):107-118. doi: 10.1124/jpet.119.261800. Epub 2019 Nov 15.

PMID:
31732698
3.

HSD10 mitochondrial disease: p.Leu122Val variant, mild clinical phenotype, and founder effect in French-Canadian patients from Quebec.

Waters PJ, Lace B, Buhas D, Gravel S, Cyr D, Boucher RM, Bernard G, Lévesque S, Maranda B.

Mol Genet Genomic Med. 2019 Dec;7(12):e1000. doi: 10.1002/mgg3.1000. Epub 2019 Oct 26.

4.

Occupational exposure to wood dust and risk of lung cancer: the ICARE study.

Matrat M, Radoï L, Févotte J, Guida F, Cénée S, Cyr D, Sanchez M, Menvielle G, Schmaus A, Marrer E, Luce D, Stücker I; ICARE Study Group.

Occup Environ Med. 2019 Dec;76(12):901-907. doi: 10.1136/oemed-2019-105802. Epub 2019 Sep 19.

PMID:
31537717
5.

BETA-DEFENSIN126 IS CORRELATED WITH SPERM MOTILITY IN FERTILE AND INFERTILE MEN.

Aram R, Chan PTK, Cyr DG.

Biol Reprod. 2019 Aug 28. pii: ioz171. doi: 10.1093/biolre/ioz171. [Epub ahead of print]

PMID:
31504198
6.

Poor Perceived Health is Associated with Current use of Electronic Cigarette among Current and Former Smokers: Findings from the CONSTANCES Cohort.

Lequy E, Wiernik E, Cyr D, Nadif R, Lemogne C, Gomajee R, Goldberg M, Zins M, Airagnes G.

Eur Addict Res. 2019;25(6):310-319. doi: 10.1159/000502517. Epub 2019 Sep 4.

PMID:
31484193
7.

Evaluation of Corneal Damage After Lacrimal Gland Excision in Male and Female Mice.

Mecum NE, Cyr D, Malon J, Demers D, Cao L, Meng ID.

Invest Ophthalmol Vis Sci. 2019 Aug 1;60(10):3264-3274. doi: 10.1167/iovs.18-26457.

8.

Prenatal exposure to betamethasone causes intergenerational impairment of epididymal development in the rat.

Kempinas WG, Borges CS, Leite GAA, Figueiredo TM, Gregory M, Cyr DG.

Andrology. 2019 Sep;7(5):719-729. doi: 10.1111/andr.12657. Epub 2019 Jun 27.

PMID:
31250541
9.

Tissue regeneration and the epididymal stem cell.

Pinel L, Mandon M, Cyr DG.

Andrology. 2019 Sep;7(5):618-630. doi: 10.1111/andr.12635. Epub 2019 Apr 29. Review.

PMID:
31033244
10.

A pathway to value-based care of chronic rhinosinusitis using a claims database.

Denneny JC 3rd, Cyr DD, Witsell DL, Brereton J, Schulz K.

Laryngoscope Investig Otolaryngol. 2018 Dec 28;4(1):193-206. doi: 10.1002/lio2.232. eCollection 2019 Feb.

11.

Baseline Characteristics and Risk Profiles of Participants in the ISCHEMIA Randomized Clinical Trial.

Hochman JS, Reynolds HR, Bangalore S, O'Brien SM, Alexander KP, Senior R, Boden WE, Stone GW, Goodman SG, Lopes RD, Lopez-Sendon J, White HD, Maggioni AP, Shaw LJ, Min JK, Picard MH, Berman DS, Chaitman BR, Mark DB, Spertus JA, Cyr DD, Bhargava B, Ruzyllo W, Wander GS, Chernyavskiy AM, Rosenberg YD, Maron DJ; ISCHEMIA Research Group.

JAMA Cardiol. 2019 Mar 1;4(3):273-286. doi: 10.1001/jamacardio.2019.0014.

PMID:
30810700
12.

Preoperative Management of Chronic Rhinosinusitis Prior to Office Balloon Sinus Dilation: A 2011-2014 MarketScan® Analysis.

Jang DW, Abraham C, Cyr DD, Schulz K, Abi Hachem R, Witsell DL.

Am J Rhinol Allergy. 2019 Jul;33(4):347-353. doi: 10.1177/1945892419829335. Epub 2019 Feb 7. No abstract available.

PMID:
30732455
13.

Days Alive and Out of Hospital: Exploring a Patient-Centered, Pragmatic Outcome in a Clinical Trial of Patients With Acute Coronary Syndromes.

Fanaroff AC, Cyr D, Neely ML, Bakal J, White HD, Fox KAA, Armstrong PW, Lopes RD, Ohman EM, Roe MT.

Circ Cardiovasc Qual Outcomes. 2018 Dec;11(12):e004755. doi: 10.1161/CIRCOUTCOMES.118.004755.

14.

Operational modifications for the development of nitrifying bacteria in a large-scale biological aerated filter and its impact on wastewater treatment.

Bourgeois FR, Monette F, Cyr DG.

Water Sci Technol. 2018 Nov;78(8):1704-1714. doi: 10.2166/wst.2018.447.

PMID:
30500794
15.

Function, evolution, and structure of J-domain proteins.

Kampinga HH, Andreasson C, Barducci A, Cheetham ME, Cyr D, Emanuelsson C, Genevaux P, Gestwicki JE, Goloubinoff P, Huerta-Cepas J, Kirstein J, Liberek K, Mayer MP, Nagata K, Nillegoda NB, Pulido P, Ramos C, De Los Rios P, Rospert S, Rosenzweig R, Sahi C, Taipale M, Tomiczek B, Ushioda R, Young JC, Zimmermann R, Zylicz A, Zylicz M, Craig EA, Marszalek J.

Cell Stress Chaperones. 2019 Jan;24(1):7-15. doi: 10.1007/s12192-018-0948-4. Epub 2018 Nov 26.

16.

Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia.

Scott WK, Medie FM, Ruffin F, Sharma-Kuinkel BK, Cyr DD, Guo S, Dykxhoorn DM, Skov RL, Bruun NE, Dahl A, Lerche CJ, Petersen A, Larsen AR, Lauridsen TK, Johansen HK, Ullum H, Sørensen E, Hassager C, Bundgaard H, Schønheyder HC, Torp-Pedersen C, Østergaard LB, Arpi M, Rosenvinge F, Erikstrup LT, Chehri M, Søgaard P, Andersen PS, Fowler VG Jr.

PLoS Genet. 2018 Oct 5;14(10):e1007667. doi: 10.1371/journal.pgen.1007667. eCollection 2018 Oct.

17.

A special issue on the effects of toxicants on cellular junctions in development and reproduction.

Cyr DG, Gregory M.

Reprod Toxicol. 2019 Jan;83:80-81. doi: 10.1016/j.reprotox.2018.08.019. Epub 2018 Aug 30. No abstract available.

PMID:
30172850
18.

Cellular junctions in the epididymis, a critical parameter for understanding male reproductive toxicology.

Cyr DG, Dufresne J, Gregory M.

Reprod Toxicol. 2018 Oct;81:207-219. doi: 10.1016/j.reprotox.2018.08.013. Epub 2018 Aug 18. Review.

PMID:
30130578
19.

Occupational exposure to flour dust and the risk of head and neck cancer.

Carton M, Menvielle G, Cyr D, Sanchez M, Pilorget C, Guizard AV, Stücker I, Luce D; Icare Study Group.

Am J Ind Med. 2018 Oct;61(10):869-873. doi: 10.1002/ajim.22899. Epub 2018 Aug 19.

PMID:
30124232
20.

Balloon Catheter Dilation of the Sinuses: A 2011-2014 MarketScan Analysis.

Jang DW, Abraham C, Cyr DD, Schulz K, Abi Hachem R, Witsell DL.

Otolaryngol Head Neck Surg. 2018 Aug 7:194599818791811. doi: 10.1177/0194599818791811. [Epub ahead of print]

PMID:
30084308
21.

Effects of prostaglandin E2 on gap junction protein alpha 1 in the rat epididymis.

Gregory M, Cyr DG.

Biol Reprod. 2019 Jan 1;100(1):123-132. doi: 10.1093/biolre/ioy171.

PMID:
30060123
22.

Idiopathic Sudden Sensorineural Hearing Loss Is Not a Sentinel Event for Acute Myocardial Infarction.

Crowson MG, Mulder H, Cyr DD, Langman AW, Lee WT, Parham K, Pynnonen MA, Schulz K, Shin JJ, Witsell D, Vambutas A.

Otol Neurotol. 2018 Aug;39(7):e518-e523. doi: 10.1097/MAO.0000000000001868.

23.

Early discontinuation of prasugrel or clopidogrel in acute coronary syndromes: insights from the TRILOGY ACS trial.

Yan AT, Roe MT, Neely M, Cyr DD, White H, Fox KAA, Prabhakaran D, Armstrong PW, Ohman EM, Goodman SG.

Coron Artery Dis. 2018 Sep;29(6):469-476. doi: 10.1097/MCA.0000000000000623.

PMID:
29652672
24.

Net clinical benefit of rivaroxaban compared with warfarin in atrial fibrillation: Results from ROCKET AF.

Barnett AS, Cyr DD, Goodman SG, Levitan BS, Yuan Z, Hankey GJ, Singer DE, Becker RC, Breithardt G, Berkowitz SD, Halperin JL, Hacke W, Mahaffey KW, Nessel CC, Fox KAA, Patel MR, Piccini JP.

Int J Cardiol. 2018 Apr 15;257:78-83. doi: 10.1016/j.ijcard.2017.06.110.

PMID:
29506743
25.

Harvesting interacts with climate change to affect future habitat quality of a focal species in eastern Canada's boreal forest.

Tremblay JA, Boulanger Y, Cyr D, Taylor AR, Price DT, St-Laurent MH.

PLoS One. 2018 Feb 7;13(2):e0191645. doi: 10.1371/journal.pone.0191645. eCollection 2018.

26.

Occupational exposure to organic solvents and risk of male breast cancer: a European multicenter case-control study.

Laouali N, Pilorget C, Cyr D, Neri M, Kaerlev L, Sabroe S, Gorini G, Richiardi L, Morales-Suárez-Varela M, Llopis-Gonzalez A, Ahrens W, Jöckel KH, Afonso N, Eriksson M, Merletti E, Olsen J, Lynge E, Guénel P.

Scand J Work Environ Health. 2018 May 1;44(3):310-322. doi: 10.5271/sjweh.3717. Epub 2018 Feb 6.

PMID:
29405242
27.

Mildly elevated succinylacetone and normal liver function in compound heterozygotes with pathogenic and pseudodeficient FAH alleles.

Yang H, Rossignol F, Cyr D, Laframboise R, Wang SP, Soucy JF, Berthier MT, Giguère Y, Waters PJ, Mitchell GA; Québec NTBC Study Group.

Mol Genet Metab Rep. 2017 Dec 27;14:55-58. doi: 10.1016/j.ymgmr.2017.12.002. eCollection 2018 Mar.

28.

Determinants of Variation in Pneumonia Rates After Coronary Artery Bypass Grafting.

Brescia AA, Rankin JS, Cyr DD, Jacobs JP, Prager RL, Zhang M, Matsouaka RA, Harrington SD, Dokholyan RS, Bolling SF, Fishstrom A, Pasquali SK, Shahian DM, Likosky DS; Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative.

Ann Thorac Surg. 2018 Feb;105(2):513-520. doi: 10.1016/j.athoracsur.2017.08.012. Epub 2017 Nov 23.

29.

The Risk of Cardiac Device-Related Infection in Bacteremic Patients Is Species Specific: Results of a 12-Year Prospective Cohort.

Maskarinec SA, Thaden JT, Cyr DD, Ruffin F, Souli M, Fowler VG.

Open Forum Infect Dis. 2017 Jun 21;4(3):ofx132. doi: 10.1093/ofid/ofx132. eCollection 2017 Summer.

30.

Conversion From Off-Pump Coronary Artery Bypass Grafting to On-Pump Coronary Artery Bypass Grafting.

Keeling B, Thourani V, Aliawadi G, Kim S, Cyr D, Badhwar V, Jacobs JP, Brennan JM, Meza J, Matsouaka R, Halkos ME.

Ann Thorac Surg. 2017 Oct;104(4):1267-1274. doi: 10.1016/j.athoracsur.2017.03.032. Epub 2017 Jun 11.

PMID:
28610886
31.

Candidate genes on murine chromosome 8 are associated with susceptibility to Staphylococcus aureus infection in mice and are involved with Staphylococcus aureus septicemia in humans.

Yan Q, Ahn SH, Medie FM, Sharma-Kuinkel BK, Park LP, Scott WK, Deshmukh H, Tsalik EL, Cyr DD, Woods CW, Yu CA, Adams C, Qi R, Hansen B, Fowler VG Jr.

PLoS One. 2017 Jun 8;12(6):e0179033. doi: 10.1371/journal.pone.0179033. eCollection 2017.

32.

Dual antiplatelet therapy in patients with diabetes and acute coronary syndromes managed without revascularization.

Dalby AJ, Gottlieb S, Cyr DD, Magnus Ohman E, McGuire DK, Ruzyllo W, Bhatt DL, Wiviott SD, Winters KJ, Fox KAA, Armstrong PW, White HD, Prabhakaran D, Roe MT; TRILOGY ACS Investigators.

Am Heart J. 2017 Jun;188:156-166. doi: 10.1016/j.ahj.2017.03.015. Epub 2017 Mar 27.

PMID:
28577671
33.

Endoplasmic reticulum stress-induced degradation of DNAJB12 stimulates BOK accumulation and primes cancer cells for apoptosis.

Sopha P, Ren HY, Grove DE, Cyr DM.

J Biol Chem. 2017 Jul 14;292(28):11792-11803. doi: 10.1074/jbc.M117.785113. Epub 2017 May 23.

34.

Betamethasone causes intergenerational reproductive impairment in male rats.

Borges CDS, Pacheco TL, da Silva KP, Fernandes FH, Gregory M, Pupo AS, Salvadori DMF, Cyr DG, Kempinas WG.

Reprod Toxicol. 2017 Aug;71:108-117. doi: 10.1016/j.reprotox.2017.04.012. Epub 2017 May 10.

PMID:
28501545
35.

Relation of Risk of Stroke in Patients With Atrial Fibrillation to Body Mass Index (from Patients Treated With Rivaroxaban and Warfarin in the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation Trial).

Balla SR, Cyr DD, Lokhnygina Y, Becker RC, Berkowitz SD, Breithardt G, Fox KAA, Hacke W, Halperin JL, Hankey GJ, Mahaffey KW, Nessel CC, Piccini JP, Singer DE, Patel MR.

Am J Cardiol. 2017 Jun 15;119(12):1989-1996. doi: 10.1016/j.amjcard.2017.03.028. Epub 2017 Mar 29.

PMID:
28477860
36.

Relationship Between Peak Troponin Values and Long-Term Ischemic Events Among Medically Managed Patients With Acute Coronary Syndromes.

Goldstein SA, Newby LK, Cyr DD, Neely M, Lüscher TF, Brown EB, White HD, Ohman EM, Roe MT, Hamm CW.

J Am Heart Assoc. 2017 Apr 11;6(4). pii: e005334. doi: 10.1161/JAHA.116.005334.

37.

Evaluating genetic susceptibility to Staphylococcus aureus bacteremia in African Americans using admixture mapping.

Cyr DD, Allen AS, Du GJ, Ruffin F, Adams C, Thaden JT, Maskarinec SA, Souli M, Guo S, Dykxhoorn DM, Scott WK, Fowler VG Jr.

Genes Immun. 2017 Mar;18(2):95-99. doi: 10.1038/gene.2017.6. Epub 2017 Mar 23.

38.

National Database Analysis of Single-Level versus Multilevel Sleep Surgery.

Brietzke SE, Ishman SL, Cohen S, Cyr DD, Shin JJ, Kezirian EJ.

Otolaryngol Head Neck Surg. 2017 May;156(5):955-961. doi: 10.1177/0194599817696503. Epub 2017 Mar 21.

PMID:
28322112
39.

Self-Reevaluation and Anticipated Regret Did Not Change Attitude, Nor Perceived Distance in an Online Context.

Crutzen R, Cyr D, Taylor SE, Lim E, Ruiter RA.

Front Psychol. 2017 Jan 11;7:2038. doi: 10.3389/fpsyg.2016.02038. eCollection 2016.

40.

Occupational exposure to solvents and risk of head and neck cancer in women: a population-based case-control study in France.

Carton M, Barul C, Menvielle G, Cyr D, Sanchez M, Pilorget C, Trétarre B, Stücker I, Luce D; ICARE Study Group.

BMJ Open. 2017 Jan 9;7(1):e012833. doi: 10.1136/bmjopen-2016-012833.

41.

Focal Adhesion Kinase-mediated Phosphorylation of Beclin1 Protein Suppresses Cardiomyocyte Autophagy and Initiates Hypertrophic Growth.

Cheng Z, Zhu Q, Dee R, Opheim Z, Mack CP, Cyr DM, Taylor JM.

J Biol Chem. 2017 Feb 10;292(6):2065-2079. doi: 10.1074/jbc.M116.758268. Epub 2016 Dec 19.

42.

Hypersuccinylacetonaemia and normal liver function in maleylacetoacetate isomerase deficiency.

Yang H, Al-Hertani W, Cyr D, Laframboise R, Parizeault G, Wang SP, Rossignol F, Berthier MT, Giguère Y, Waters PJ, Mitchell GA; Québec NTBC Study Group.

J Med Genet. 2017 Apr;54(4):241-247. doi: 10.1136/jmedgenet-2016-104289. Epub 2016 Nov 22.

PMID:
27876694
43.

Musculoskeletal pain at various anatomical sites and socioeconomic position: Results of a national survey.

Leclerc A, Chastang JF, Taiba R, Pascal P, Cyr D, Plouvier S, Descatha A.

Rev Epidemiol Sante Publique. 2016 Oct;64(5):331-339. doi: 10.1016/j.respe.2016.04.035. Epub 2016 Oct 24.

PMID:
27789068
44.

Nonadherence to Guideline Recommendations for Tympanostomy Tube Insertion in Children Based on Mega-database Claims Analysis.

Sajisevi M, Schulz K, Cyr DD, Wojdyla D, Rosenfeld RM, Tucci D, Witsell DL.

Otolaryngol Head Neck Surg. 2017 Jan;156(1):87-95. doi: 10.1177/0194599816669499. Epub 2016 Oct 3.

45.

Use of Dual Antiplatelet Therapy and Patient Outcomes in Those Undergoing Percutaneous Coronary Intervention: The ROCKET AF Trial.

Sherwood MW, Cyr DD, Jones WS, Becker RC, Berkowitz SD, Washam JB, Breithardt G, Fox KA, Halperin JL, Hankey GJ, Singer DE, Piccini JP, Nessel CC, Mahaffey KW, Patel MR.

JACC Cardiovasc Interv. 2016 Aug 22;9(16):1694-702. doi: 10.1016/j.jcin.2016.05.039.

46.

1-Year Outcomes of FFRCT-Guided Care in Patients With Suspected Coronary Disease: The PLATFORM Study.

Douglas PS, De Bruyne B, Pontone G, Patel MR, Norgaard BL, Byrne RA, Curzen N, Purcell I, Gutberlet M, Rioufol G, Hink U, Schuchlenz HW, Feuchtner G, Gilard M, Andreini D, Jensen JM, Hadamitzky M, Chiswell K, Cyr D, Wilk A, Wang F, Rogers C, Hlatky MA; PLATFORM Investigators.

J Am Coll Cardiol. 2016 Aug 2;68(5):435-445. doi: 10.1016/j.jacc.2016.05.057.

47.

Dual Antiplatelet Therapy and Outcomes in Patients With Atrial Fibrillation and Acute Coronary Syndromes Managed Medically Without Revascularization: Insights From the TRILOGY ACS Trial.

Jackson LR 2nd, Piccini JP, Cyr DD, Roe MT, Neely ML, Martinez F, Lüscher TF, Lopes RD, Winters KJ, White HD, Armstrong PW, Fox KA, Prabhakaran D, Bhatt DL, Magnus Ohman E, Corbalán R.

Clin Cardiol. 2016 Sep;39(9):497-506. doi: 10.1002/clc.22562. Epub 2016 Jul 28.

48.

Contaminants of Emerging Concern: From the Detection to Their Effects on Human Health.

Barbosa Junior F, Campiglia A, Rocha B, Cyr D.

Biomed Res Int. 2016;2016:3159385. doi: 10.1155/2016/3159385. Epub 2016 Jun 20. No abstract available.

49.

Restoration of R117H CFTR folding and function in human airway cells through combination treatment with VX-809 and VX-770.

Gentzsch M, Ren HY, Houck SA, Quinney NL, Cholon DM, Sopha P, Chaudhry IG, Das J, Dokholyan NV, Randell SH, Cyr DM.

Am J Physiol Lung Cell Mol Physiol. 2016 Sep 1;311(3):L550-9. doi: 10.1152/ajplung.00186.2016. Epub 2016 Jul 8.

50.

Subversion of Autophagy by Kaposi's Sarcoma-Associated Herpesvirus Impairs Oncogene-Induced Senescence.

Leidal AM, Cyr DP, Hill RJ, Lee PW, McCormick C.

Cell Host Microbe. 2016 Jun 8;19(6):901. doi: 10.1016/j.chom.2016.05.006. No abstract available.

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