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Items: 1 to 50 of 76

1.

Human endothelial cells size-select their secretory granules for exocytosis to modulate their functional output.

McCormack JJ, Harrison-Lavoie KJ, Cutler DF.

J Thromb Haemost. 2019 Sep 13. doi: 10.1111/jth.14634. [Epub ahead of print]

PMID:
31519030
2.

A GBF1-Dependent Mechanism for Environmentally Responsive Regulation of ER-Golgi Transport.

Lopes-da-Silva M, McCormack JJ, Burden JJ, Harrison-Lavoie KJ, Ferraro F, Cutler DF.

Dev Cell. 2019 Jun 3;49(5):786-801.e6. doi: 10.1016/j.devcel.2019.04.006. Epub 2019 May 2.

3.

Tuning the endothelial response: differential release of exocytic cargos from Weibel-Palade bodies.

Nightingale TD, McCormack JJ, Grimes W, Robinson C, Lopes da Silva M, White IJ, Vaughan A, Cramer LP, Cutler DF.

J Thromb Haemost. 2018 Sep;16(9):1873-1886. doi: 10.1111/jth.14218. Epub 2018 Aug 12.

4.

Weibel-Palade bodies at a glance.

McCormack JJ, Lopes da Silva M, Ferraro F, Patella F, Cutler DF.

J Cell Sci. 2017 Nov 1;130(21):3611-3617. doi: 10.1242/jcs.208033. Epub 2017 Nov 1. Review.

5.

Clathrin-mediated post-fusion membrane retrieval influences the exocytic mode of endothelial Weibel-Palade bodies.

Stevenson NL, White IJ, McCormack JJ, Robinson C, Cutler DF, Nightingale TD.

J Cell Sci. 2017 Aug 1;130(15):2591-2605. doi: 10.1242/jcs.200840. Epub 2017 Jul 3.

6.

Corrigendum: Image-based siRNA screen to identify kinases regulating Weibel-Palade body size control using electroporation.

Ketteler R, Freeman J, Stevenson N, Ferraro F, Bata N, Cutler DF, Kriston-Vizi J.

Sci Data. 2017 Jun 27;4:170086. doi: 10.1038/sdata.2017.86.

7.

Super-resolution microscopy in the diagnosis of platelet granule disorders.

Knight AE, Gomez K, Cutler DF.

Expert Rev Hematol. 2017 May;10(5):375-381. doi: 10.1080/17474086.2017.1315302. Epub 2017 Apr 13. Review.

8.

Image-based siRNA screen to identify kinases regulating Weibel-Palade body size control using electroporation.

Ketteler R, Freeman J, Ferraro F, Bata N, Cutler DF, Kriston-Vizi J, Stevenson N.

Sci Data. 2017 Mar 1;4:170022. doi: 10.1038/sdata.2017.22. Erratum in: Sci Data. 2017 Jun 27;4:170086.

9.

BLOC-2 subunit HPS6 deficiency affects the tubulation and secretion of von Willebrand factor from mouse endothelial cells.

Ma J, Zhang Z, Yang L, Kriston-Vizi J, Cutler DF, Li W.

J Genet Genomics. 2016 Dec 20;43(12):686-693. doi: 10.1016/j.jgg.2016.09.007. Epub 2016 Oct 21.

10.

Erratum: Weibel-Palade body size modulates the adhesive activity of its von Willebrand Factor cargo in cultured endothelial cells.

Ferraro F, da Silva ML, Grimes W, Lee HK, Ketteler R, Kriston-Vizi J, Cutler DF.

Sci Rep. 2016 Sep 26;6:33938. doi: 10.1038/srep33938. No abstract available.

11.

Weibel-Palade body size modulates the adhesive activity of its von Willebrand Factor cargo in cultured endothelial cells.

Ferraro F, Mafalda Lopes da S, Grimes W, Lee HK, Ketteler R, Kriston-Vizi J, Cutler DF.

Sci Rep. 2016 Aug 31;6:32473. doi: 10.1038/srep32473.

12.

Coming or going? Un-BLOC-ing delivery and recycling pathways during melanosome maturation.

Futter CE, Cutler DF.

J Cell Biol. 2016 Aug 1;214(3):245-7. doi: 10.1083/jcb.201607023.

13.

von Willebrand factor multimerization and the polarity of secretory pathways in endothelial cells.

Lopes da Silva M, Cutler DF.

Blood. 2016 Jul 14;128(2):277-85. doi: 10.1182/blood-2015-10-677054. Epub 2016 Apr 22.

14.

Type II PI4-kinases control Weibel-Palade body biogenesis and von Willebrand factor structure in human endothelial cells.

Lopes da Silva M, O'Connor MN, Kriston-Vizi J, White IJ, Al-Shawi R, Simons JP, Mössinger J, Haucke V, Cutler DF.

J Cell Sci. 2016 May 15;129(10):2096-105. doi: 10.1242/jcs.187864. Epub 2016 Apr 11.

15.

Super-resolution microscopy as a potential approach to diagnosis of platelet granule disorders.

Westmoreland D, Shaw M, Grimes W, Metcalf DJ, Burden JJ, Gomez K, Knight AE, Cutler DF.

J Thromb Haemost. 2016 Apr;14(4):839-49. doi: 10.1111/jth.13269. Epub 2016 Mar 17.

16.

Photoreceptor phagosome processing defects and disturbed autophagy in retinal pigment epithelium of Cln3Δex1-6 mice modelling juvenile neuronal ceroid lipofuscinosis (Batten disease).

Wavre-Shapton ST, Calvi AA, Turmaine M, Seabra MC, Cutler DF, Futter CE, Mitchison HM.

Hum Mol Genet. 2015 Dec 15;24(24):7060-74. doi: 10.1093/hmg/ddv406. Epub 2015 Oct 8.

17.

Regulation of melanosome number, shape and movement in the zebrafish retinal pigment epithelium by OA1 and PMEL.

Burgoyne T, O'Connor MN, Seabra MC, Cutler DF, Futter CE.

J Cell Sci. 2015 Apr 1;128(7):1400-7. doi: 10.1242/jcs.164400. Epub 2015 Feb 17.

18.

A two-tier Golgi-based control of organelle size underpins the functional plasticity of endothelial cells.

Ferraro F, Kriston-Vizi J, Metcalf DJ, Martin-Martin B, Freeman J, Burden JJ, Westmoreland D, Dyer CE, Knight AE, Ketteler R, Cutler DF.

Dev Cell. 2014 May 12;29(3):292-304. doi: 10.1016/j.devcel.2014.03.021. Epub 2014 May 1.

19.

G protein-coupled receptor kinase 2 moderates recruitment of THP-1 cells to the endothelium by limiting histamine-invoked Weibel-Palade body exocytosis.

Stevenson NL, Martin-Martin B, Freeman J, Kriston-Vizi J, Ketteler R, Cutler DF.

J Thromb Haemost. 2014 Feb;12(2):261-72.

PMID:
24738138
20.

G protein-coupled receptor kinase 2 moderates recruitment of THP-1 cells to the endothelium by limiting histamine-invoked Weibel-Palade body exocytosis.

Stevenson NL, Martin-Martin B, Freeman J, Kriston-Vizi J, Ketteler R, Cutler DF.

J Thromb Haemost. 2014 Feb;12(2):261-272. doi: 10.1111/jth.12470.

21.

Cellular and molecular basis of von Willebrand disease: studies on blood outgrowth endothelial cells.

Starke RD, Paschalaki KE, Dyer CE, Harrison-Lavoie KJ, Cutler JA, McKinnon TA, Millar CM, Cutler DF, Laffan MA, Randi AM.

Blood. 2013 Apr 4;121(14):2773-84. doi: 10.1182/blood-2012-06-435727. Epub 2013 Jan 25.

22.

Meeting the Housing and Care Needs of Older Homeless Adults: A Permanent Supportive Housing Program Targeting Homeless Elders.

Brown RT, Thomas ML, Cutler DF, Hinderlie M.

Seniors Hous Care J. 2013 Jan 1;21(1):126-135.

23.

Actin coats and rings promote regulated exocytosis.

Nightingale TD, Cutler DF, Cramer LP.

Trends Cell Biol. 2012 Jun;22(6):329-37. doi: 10.1016/j.tcb.2012.03.003. Epub 2012 Apr 28. Review.

PMID:
22543050
24.

Actomyosin II contractility expels von Willebrand factor from Weibel-Palade bodies during exocytosis.

Nightingale TD, White IJ, Doyle EL, Turmaine M, Harrison-Lavoie KJ, Webb KF, Cramer LP, Cutler DF.

J Cell Biol. 2011 Aug 22;194(4):613-29. doi: 10.1083/jcb.201011119. Epub 2011 Aug 15.

25.

CD63 is an essential cofactor to leukocyte recruitment by endothelial P-selectin.

Doyle EL, Ridger V, Ferraro F, Turmaine M, Saftig P, Cutler DF.

Blood. 2011 Oct 13;118(15):4265-73. doi: 10.1182/blood-2010-11-321489. Epub 2011 Jul 29.

PMID:
21803846
26.

Myosin Va acts in concert with Rab27a and MyRIP to regulate acute von-Willebrand factor release from endothelial cells.

Rojo Pulido I, Nightingale TD, Darchen F, Seabra MC, Cutler DF, Gerke V.

Traffic. 2011 Oct;12(10):1371-82. doi: 10.1111/j.1600-0854.2011.01248.x. Epub 2011 Aug 5.

27.

A role for Rab10 in von Willebrand factor release discovered by an AP-1 interactor screen in C. elegans.

Michaux G, Dyer CE, Nightingale TD, Gallaud E, Nurrish S, Cutler DF.

J Thromb Haemost. 2011 Feb;9(2):392-401. doi: 10.1111/j.1538-7836.2010.04138.x.

28.

Endothelial von Willebrand factor regulates angiogenesis.

Starke RD, Ferraro F, Paschalaki KE, Dryden NH, McKinnon TA, Sutton RE, Payne EM, Haskard DO, Hughes AD, Cutler DF, Laffan MA, Randi AM.

Blood. 2011 Jan 20;117(3):1071-80. doi: 10.1182/blood-2010-01-264507. Epub 2010 Nov 3.

29.

Rab27a and MyRIP regulate the amount and multimeric state of VWF released from endothelial cells.

Nightingale TD, Pattni K, Hume AN, Seabra MC, Cutler DF.

Blood. 2009 May 14;113(20):5010-8. doi: 10.1182/blood-2008-09-181206. Epub 2009 Mar 6. Erratum in: Blood. 2011 Mar 24;117(12):3476.

30.

Fishing for platelets.

Cutler DF.

Blood. 2009 Feb 12;113(7):1397-8. doi: 10.1182/blood-2008-11-188524.

PMID:
19221043
31.

Loss of the Batten disease gene CLN3 prevents exit from the TGN of the mannose 6-phosphate receptor.

Metcalf DJ, Calvi AA, Seaman MNj, Mitchison HM, Cutler DF.

Traffic. 2008 Nov;9(11):1905-14. doi: 10.1111/j.1600-0854.2008.00807.x. Epub 2008 Aug 4.

32.

Aftiphilin and gamma-synergin are required for secretagogue sensitivity of Weibel-Palade bodies in endothelial cells.

Lui-Roberts WW, Ferraro F, Nightingale TD, Cutler DF.

Mol Biol Cell. 2008 Dec;19(12):5072-81. doi: 10.1091/mbc.E08-03-0301. Epub 2008 Sep 24.

33.

Formation and function of Weibel-Palade bodies.

Metcalf DJ, Nightingale TD, Zenner HL, Lui-Roberts WW, Cutler DF.

J Cell Sci. 2008 Jan 1;121(Pt 1):19-27.

34.

A function retained by the common mutant CLN3 protein is responsible for the late onset of juvenile neuronal ceroid lipofuscinosis.

Kitzmüller C, Haines RL, Codlin S, Cutler DF, Mole SE.

Hum Mol Genet. 2008 Jan 15;17(2):303-12. Epub 2007 Oct 18.

PMID:
17947292
35.

Lysosome-related organelles: driving post-Golgi compartments into specialisation.

Raposo G, Marks MS, Cutler DF.

Curr Opin Cell Biol. 2007 Aug;19(4):394-401. Epub 2007 Jul 12. Review.

36.

High-pressure freezing provides insights into Weibel-Palade body biogenesis.

Zenner HL, Collinson LM, Michaux G, Cutler DF.

J Cell Sci. 2007 Jun 15;120(Pt 12):2117-25. Epub 2007 May 29.

37.

P-selectin and CD63 use different mechanisms for delivery to Weibel-Palade bodies.

Harrison-Lavoie KJ, Michaux G, Hewlett L, Kaur J, Hannah MJ, Lui-Roberts WW, Norman KE, Cutler DF.

Traffic. 2006 Jun;7(6):647-62.

38.

The physiological function of von Willebrand's factor depends on its tubular storage in endothelial Weibel-Palade bodies.

Michaux G, Abbitt KB, Collinson LM, Haberichter SL, Norman KE, Cutler DF.

Dev Cell. 2006 Feb;10(2):223-32.

39.

P-selectin binds to the D'-D3 domains of von Willebrand factor in Weibel-Palade bodies.

Michaux G, Pullen TJ, Haberichter SL, Cutler DF.

Blood. 2006 May 15;107(10):3922-4. Epub 2006 Jan 17.

PMID:
16418330
40.

Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes.

Theos AC, Tenza D, Martina JA, Hurbain I, Peden AA, Sviderskaya EV, Stewart A, Robinson MS, Bennett DC, Cutler DF, Bonifacino JS, Marks MS, Raposo G.

Mol Biol Cell. 2005 Nov;16(11):5356-72. Epub 2005 Sep 14.

41.

An AP-1/clathrin coat plays a novel and essential role in forming the Weibel-Palade bodies of endothelial cells.

Lui-Roberts WW, Collinson LM, Hewlett LJ, Michaux G, Cutler DF.

J Cell Biol. 2005 Aug 15;170(4):627-36. Epub 2005 Aug 8.

42.

CLN6, which is associated with a lysosomal storage disease, is an endoplasmic reticulum protein.

Mole SE, Michaux G, Codlin S, Wheeler RB, Sharp JD, Cutler DF.

Exp Cell Res. 2004 Aug 15;298(2):399-406.

PMID:
15265688
43.

Sorting nexin 17 accelerates internalization yet retards degradation of P-selectin.

Williams R, Schlüter T, Roberts MS, Knauth P, Bohnensack R, Cutler DF.

Mol Biol Cell. 2004 Jul;15(7):3095-105. Epub 2004 Apr 30.

44.

How to roll an endothelial cigar: the biogenesis of Weibel-Palade bodies.

Michaux G, Cutler DF.

Traffic. 2004 Feb;5(2):69-78. Review.

45.

Weibel-Palade bodies recruit Rab27 by a content-driven, maturation-dependent mechanism that is independent of cell type.

Hannah MJ, Hume AN, Arribas M, Williams R, Hewlett LJ, Seabra MC, Cutler DF.

J Cell Sci. 2003 Oct 1;116(Pt 19):3939-48. Epub 2003 Aug 19.

46.

Analysis of intracellular storage and regulated secretion of 3 von Willebrand disease-causing variants of von Willebrand factor.

Michaux G, Hewlett LJ, Messenger SL, Goodeve AC, Peake IR, Daly ME, Cutler DF.

Blood. 2003 Oct 1;102(7):2452-8. Epub 2003 Jun 5.

PMID:
12791651
47.

Biogenesis of Weibel-Palade bodies.

Hannah MJ, Williams R, Kaur J, Hewlett LJ, Cutler DF.

Semin Cell Dev Biol. 2002 Aug;13(4):313-24. Review.

PMID:
12243731
48.

Introduction: lysosome-related organelles.

Cutler DF.

Semin Cell Dev Biol. 2002 Aug;13(4):261-2. Review. No abstract available.

PMID:
12243724
49.
50.

Synaptotagmin I-DeltaC2B. A novel synaptotagmin isoform with a single C2 domain in the bovine adrenal medulla.

Hewitt EW, Tao JX, Strasser JE, Cutler DF, Dean GE.

Biochim Biophys Acta. 2002 Mar 19;1561(1):76-90.

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