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Items: 10


Unconventional protein secretion triggered by nutrient starvation.

Cruz-Garcia D, Malhotra V, Curwin AJ.

Semin Cell Dev Biol. 2018 Nov;83:22-28. doi: 10.1016/j.semcdb.2018.02.021. Epub 2018 Feb 28. Review.


A diacidic motif determines unconventional secretion of wild-type and ALS-linked mutant SOD1.

Cruz-Garcia D, Brouwers N, Duran JM, Mora G, Curwin AJ, Malhotra V.

J Cell Biol. 2017 Aug 9. pii: jcb.201704056. doi: 10.1083/jcb.201704056. [Epub ahead of print]


ESCRT-III drives the final stages of CUPS maturation for unconventional protein secretion.

Curwin AJ, Brouwers N, Alonso Y Adell M, Teis D, Turacchio G, Parashuraman S, Ronchi P, Malhotra V.

Elife. 2016 Apr 26;5. pii: e16299. doi: 10.7554/eLife.16299.


Remodeling of secretory compartments creates CUPS during nutrient starvation.

Cruz-Garcia D, Curwin AJ, Popoff JF, Bruns C, Duran JM, Malhotra V.

J Cell Biol. 2014 Dec 22;207(6):695-703. doi: 10.1083/jcb.201407119. Epub 2014 Dec 15.


Localization of lipid raft proteins to the plasma membrane is a major function of the phospholipid transfer protein Sec14.

Curwin AJ, Leblanc MA, Fairn GD, McMaster CR.

PLoS One. 2013;8(1):e55388. doi: 10.1371/journal.pone.0055388. Epub 2013 Jan 30.


Cofilin-mediated sorting and export of specific cargo from the Golgi apparatus in yeast.

Curwin AJ, von Blume J, Malhotra V.

Mol Biol Cell. 2012 Jun;23(12):2327-38. doi: 10.1091/mbc.E11-09-0826. Epub 2012 May 2.


Biogenesis of a novel compartment for autophagosome-mediated unconventional protein secretion.

Bruns C, McCaffery JM, Curwin AJ, Duran JM, Malhotra V.

J Cell Biol. 2011 Dec 12;195(6):979-92. doi: 10.1083/jcb.201106098. Epub 2011 Dec 5.


The Kap60-Kap95 karyopherin complex directly regulates phosphatidylcholine synthesis.

MacKinnon MA, Curwin AJ, Gaspard GJ, Suraci AB, Fernández-Murray JP, McMaster CR.

J Biol Chem. 2009 Mar 13;284(11):7376-84. doi: 10.1074/jbc.M809117200. Epub 2009 Jan 13.


Phospholipid transfer protein Sec14 is required for trafficking from endosomes and regulates distinct trans-Golgi export pathways.

Curwin AJ, Fairn GD, McMaster CR.

J Biol Chem. 2009 Mar 13;284(11):7364-75. doi: 10.1074/jbc.M808732200. Epub 2009 Jan 6.


The oxysterol binding protein Kes1p regulates Golgi apparatus phosphatidylinositol-4-phosphate function.

Fairn GD, Curwin AJ, Stefan CJ, McMaster CR.

Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15352-7. Epub 2007 Sep 19.

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