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Items: 12


From Colitis to Cancer: An Evolutionary Trajectory That Merges Maths and Biology.

Al Bakir I, Curtius K, Graham TA.

Front Immunol. 2018 Oct 16;9:2368. doi: 10.3389/fimmu.2018.02368. eCollection 2018. Review.


Implications of Epigenetic Drift in Colorectal Neoplasia.

Luebeck GE, Hazelton WD, Curtius K, Maden SK, Yu M, Carter KT, Burke W, Lampe PD, Li CI, Ulrich CM, Newcomb PA, Westerhoff M, Kaz AM, Luo Y, Inadomi JM, Grady WM.

Cancer Res. 2019 Feb 1;79(3):495-504. doi: 10.1158/0008-5472.CAN-18-1682. Epub 2018 Oct 5.


Evolutionary history of human colitis-associated colorectal cancer.

Baker AM, Cross W, Curtius K, Al Bakir I, Choi CR, Davis HL, Temko D, Biswas S, Martinez P, Williams MJ, Lindsay JO, Feakins R, Vega R, Hayes SJ, Tomlinson IPM, McDonald SAC, Moorghen M, Silver A, East JE, Wright NA, Wang LM, Rodriguez-Justo M, Jansen M, Hart AL, Leedham SJ, Graham TA.

Gut. 2018 Jul 10. pii: gutjnl-2018-316191. doi: 10.1136/gutjnl-2018-316191. [Epub ahead of print]


An evolutionary perspective on field cancerization.

Curtius K, Wright NA, Graham TA.

Nat Rev Cancer. 2018 Jan;18(1):19-32. doi: 10.1038/nrc.2017.102. Epub 2017 Dec 8. Review.


Identification of a key role of widespread epigenetic drift in Barrett's esophagus and esophageal adenocarcinoma.

Luebeck EG, Curtius K, Hazelton WD, Maden S, Yu M, Thota PN, Patil DT, Chak A, Willis JE, Grady WM.

Clin Epigenetics. 2017 Oct 16;9:113. doi: 10.1186/s13148-017-0409-4. eCollection 2017.


Evolution of Premalignant Disease.

Curtius K, Wright NA, Graham TA.

Cold Spring Harb Perspect Med. 2017 Dec 1;7(12). pii: a026542. doi: 10.1101/cshperspect.a026542. Review.


Radiofrequency Ablation of Barrett's Esophagus Reduces Esophageal Adenocarcinoma Incidence and Mortality in a Comparative Modeling Analysis.

Kroep S, Heberle CR, Curtius K, Kong CY, Lansdorp-Vogelaar I, Ali A, Wolf WA, Shaheen NJ, Spechler SJ, Rubenstein JH, Nishioka NS, Meltzer SJ, Hazelton WD, van Ballegooijen M, Tramontano AC, Gazelle GS, Luebeck EG, Inadomi JM, Hur C.

Clin Gastroenterol Hepatol. 2017 Sep;15(9):1471-1474. doi: 10.1016/j.cgh.2016.12.034. Epub 2017 Jan 12. No abstract available.


A Molecular Clock Infers Heterogeneous Tissue Age Among Patients with Barrett's Esophagus.

Curtius K, Wong CJ, Hazelton WD, Kaz AM, Chak A, Willis JE, Grady WM, Luebeck EG.

PLoS Comput Biol. 2016 May 11;12(5):e1004919. doi: 10.1371/journal.pcbi.1004919. eCollection 2016 May. Erratum in: PLoS Comput Biol. 2017 Mar 17;13(3):e1005439.


A Multiscale Model Evaluates Screening for Neoplasia in Barrett's Esophagus.

Curtius K, Hazelton WD, Jeon J, Luebeck EG.

PLoS Comput Biol. 2015 May 22;11(5):e1004272. doi: 10.1371/journal.pcbi.1004272. eCollection 2015 May.


The Role of Gastroesophageal Reflux and Other Factors during Progression to Esophageal Adenocarcinoma.

Hazelton WD, Curtius K, Inadomi JM, Vaughan TL, Meza R, Rubenstein JH, Hur C, Luebeck EG.

Cancer Epidemiol Biomarkers Prev. 2015 Jul;24(7):1012-23. doi: 10.1158/1055-9965.EPI-15-0323-T. Epub 2015 Apr 30.


Exploring the recent trend in esophageal adenocarcinoma incidence and mortality using comparative simulation modeling.

Kong CY, Kroep S, Curtius K, Hazelton WD, Jeon J, Meza R, Heberle CR, Miller MC, Choi SE, Lansdorp-Vogelaar I, van Ballegooijen M, Feuer EJ, Inadomi JM, Hur C, Luebeck EG.

Cancer Epidemiol Biomarkers Prev. 2014 Jun;23(6):997-1006. doi: 10.1158/1055-9965.EPI-13-1233. Epub 2014 Apr 1.


Impact of tumor progression on cancer incidence curves.

Luebeck EG, Curtius K, Jeon J, Hazelton WD.

Cancer Res. 2013 Feb 1;73(3):1086-96. doi: 10.1158/0008-5472.CAN-12-2198. Epub 2012 Oct 10.

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