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Dysregulated claudin-5 cycling in the inner retina causes retinal pigment epithelial cell atrophy.

Hudson N, Celkova L, Hopkins A, Greene C, Storti F, Ozaki E, Fahey E, Theodoropoulou S, Kenna PF, Humphries MM, Curtis AM, Demmons E, Browne A, Liddie S, Lawrence MS, Grimm C, Cahill MT, Humphries P, Doyle SL, Campbell M.

JCI Insight. 2019 Aug 8;4(15). pii: 130273. doi: 10.1172/jci.insight.130273. eCollection 2019 Aug 8.


Immunometabolism around the Clock.

Carroll RG, Timmons GA, Cervantes-Silva MP, Kennedy OD, Curtis AM.

Trends Mol Med. 2019 Jul;25(7):612-625. doi: 10.1016/j.molmed.2019.04.013. Epub 2019 May 29. Review.


Daily variation in macrophage phagocytosis is clock-independent and dispensable for cytokine production.

Geiger SS, Curtis AM, O'Neill LAJ, Siegel RM.

Immunology. 2019 Jun;157(2):122-136. doi: 10.1111/imm.13053. Epub 2019 Apr 16.


Child and Adolescent Sugar-Sweetened Beverage Intakes Are Longitudinally Associated with Higher Body Mass Index z Scores in a Birth Cohort Followed 17 Years.

Marshall TA, Curtis AM, Cavanaugh JE, Warren JJ, Levy SM.

J Acad Nutr Diet. 2019 Mar;119(3):425-434. doi: 10.1016/j.jand.2018.11.003. Epub 2019 Jan 9.


Bone Microdamage in Acute Knee Injury.

Selvarajah L, Curtis AM, Kennedy OD.

Curr Rheumatol Rep. 2018 Nov 21;20(12):89. doi: 10.1007/s11926-018-0791-8. Review.


Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2.

Early JO, Menon D, Wyse CA, Cervantes-Silva MP, Zaslona Z, Carroll RG, Palsson-McDermott EM, Angiari S, Ryan DG, Corcoran SE, Timmons G, Geiger SS, Fitzpatrick DJ, O'Connell D, Xavier RJ, Hokamp K, O'Neill LAJ, Curtis AM.

Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8460-E8468. doi: 10.1073/pnas.1800431115. Epub 2018 Aug 20.


Description of Child and Adolescent Beverage and Anthropometric Measures According to Adolescent Beverage Patterns.

Marshall TA, Curtis AM, Cavanaugh JE, VanBuren JM, Warren JJ, Levy SM.

Nutrients. 2018 Jul 25;10(8). pii: E958. doi: 10.3390/nu10080958.


Higher Longitudinal Milk Intakes Are Associated with Increased Height in a Birth Cohort Followed for 17 Years.

Marshall TA, Curtis AM, Cavanaugh JE, Warren JJ, Levy SM.

J Nutr. 2018 Jul 1;148(7):1144-1149. doi: 10.1093/jn/nxy071.


Circadian rhythms of melatonin and behaviour in juvenile sheep in field conditions: Effects of photoperiod, environment and weaning.

Wyse CA, Zhang X, McLaughlin M, Biello SM, Hough D, Bellingham M, Curtis AM, Robinson JE, Evans NP.

Physiol Behav. 2018 Oct 1;194:362-370. doi: 10.1016/j.physbeh.2018.06.001. Epub 2018 Jun 15.


Longitudinal associations between dental caries increment and risk factors in late childhood and adolescence.

Curtis AM, VanBuren J, Cavanaugh JE, Warren JJ, Marshall TA, Levy SM.

J Public Health Dent. 2018 Sep;78(4):321-328. doi: 10.1111/jphd.12275. Epub 2018 May 12.


Population-level seasonality in cardiovascular mortality, blood pressure, BMI and inflammatory cells in UK biobank.

Wyse CA, Celis Morales CA, Ward J, Lyall D, Smith DJ, Mackay D, Curtis AM, Bailey MES, Biello S, Gill JMR, Pell JP.

Ann Med. 2018 Aug;50(5):410-419. doi: 10.1080/07853890.2018.1472389. Epub 2018 May 18.


Impaired Production and Diurnal Regulation of Vascular RvDn-3 DPA Increase Systemic Inflammation and Cardiovascular Disease.

Colas RA, Souza PR, Walker ME, Burton M, Zasłona Z, Curtis AM, Marques RM, Dalli J.

Circ Res. 2018 Mar 16;122(6):855-863. doi: 10.1161/CIRCRESAHA.117.312472. Epub 2018 Feb 5.


Seasonality of depressive symptoms in women but not in men: A cross-sectional study in the UK Biobank cohort.

Lyall LM, Wyse CA, Celis-Morales CA, Lyall DM, Cullen B, Mackay D, Ward J, Graham N, Strawbridge RJ, Gill JMR, Ferguson A, Bailey MES, Pell JP, Curtis AM, Smith DJ.

J Affect Disord. 2018 Mar 15;229:296-305. doi: 10.1016/j.jad.2017.12.106. Epub 2018 Jan 4.


Examining caries aetiology in adolescence with structural equation modelling.

Curtis AM, Cavanaugh JE, Levy SM, VanBuren J, Marshall TA, Warren JJ.

Community Dent Oral Epidemiol. 2018 Jun;46(3):258-264. doi: 10.1111/cdoe.12359. Epub 2017 Dec 21.


Loss of the molecular clock in myeloid cells exacerbates T cell-mediated CNS autoimmune disease.

Sutton CE, Finlay CM, Raverdeau M, Early JO, DeCourcey J, Zaslona Z, O'Neill LAJ, Mills KHG, Curtis AM.

Nat Commun. 2017 Dec 12;8(1):1923. doi: 10.1038/s41467-017-02111-0.


Dental caries clusters among adolescents.

Warren JJ, Van Buren JM, Levy SM, Marshall TA, Cavanaugh JE, Curtis AM, Kolker JL, Weber-Gasparoni K.

Community Dent Oral Epidemiol. 2017 Dec;45(6):538-544. doi: 10.1111/cdoe.12317. Epub 2017 Jul 3.


The circadian protein BMAL1 in myeloid cells is a negative regulator of allergic asthma.

Zasłona Z, Case S, Early JO, Lalor SJ, McLoughlin RM, Curtis AM, O'Neill LAJ.

Am J Physiol Lung Cell Mol Physiol. 2017 Jun 1;312(6):L855-L860. doi: 10.1152/ajplung.00072.2017. Epub 2017 Mar 23.


Adverse metabolic and mental health outcomes associated with shiftwork in a population-based study of 277,168 workers in UK biobank<sup/>.

Wyse CA, Celis Morales CA, Graham N, Fan Y, Ward J, Curtis AM, Mackay D, Smith DJ, Bailey MES, Biello S, Gill JMR, Pell JP.

Ann Med. 2017 Aug;49(5):411-420. doi: 10.1080/07853890.2017.1292045. Epub 2017 Feb 26.


Immunometabolism: Is it under the eye of the clock?

Early JO, Curtis AM.

Semin Immunol. 2016 Oct;28(5):478-490. doi: 10.1016/j.smim.2016.10.006. Epub 2016 Nov 21. Review.


Trypanosoma brucei metabolite indolepyruvate decreases HIF-1α and glycolysis in macrophages as a mechanism of innate immune evasion.

McGettrick AF, Corcoran SE, Barry PJ, McFarland J, Crès C, Curtis AM, Franklin E, Corr SC, Mok KH, Cummins EP, Taylor CT, O'Neill LA, Nolan DP.

Proc Natl Acad Sci U S A. 2016 Nov 29;113(48):E7778-E7787. Epub 2016 Nov 15.


Understanding the Role of Cellular Molecular Clocks in Controlling the Innate Immune Response.

Curtis AM, Fagundes CT.

Methods Mol Biol. 2016;1390:301-16. doi: 10.1007/978-1-4939-3335-8_19.


Using Simulation to Promote Professional Development of Clinical Instructors.

Hunt CW, Curtis AM, Gore T.

J Nurs Educ. 2015 Aug;54(8):468-71. doi: 10.3928/01484834-20150717-09.


Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1.

Curtis AM, Fagundes CT, Yang G, Palsson-McDermott EM, Wochal P, McGettrick AF, Foley NH, Early JO, Chen L, Zhang H, Xue C, Geiger SS, Hokamp K, Reilly MP, Coogan AN, Vigorito E, FitzGerald GA, O'Neill LA.

Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7231-6. doi: 10.1073/pnas.1501327112. Epub 2015 May 20.


Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages.

Palsson-McDermott EM, Curtis AM, Goel G, Lauterbach MAR, Sheedy FJ, Gleeson LE, van den Bosch MWM, Quinn SR, Domingo-Fernandez R, Johnston DGW, Jiang JK, Israelsen WJ, Keane J, Thomas C, Clish C, Vander Heiden M, Xavier RJ, O'Neill LAJ.

Cell Metab. 2015 Feb 3;21(2):347. doi: 10.1016/j.cmet.2015.01.017. Epub 2015 Feb 3. No abstract available.


Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages.

Palsson-McDermott EM, Curtis AM, Goel G, Lauterbach MA, Sheedy FJ, Gleeson LE, van den Bosch MW, Quinn SR, Domingo-Fernandez R, Johnston DG, Jiang JK, Israelsen WJ, Keane J, Thomas C, Clish C, Vander Heiden M, Xavier RJ, O'Neill LA.

Cell Metab. 2015 Jan 6;21(1):65-80. doi: 10.1016/j.cmet.2014.12.005. Erratum in: Cell Metab. 2015 Feb 3;21(2):347. Jiang, Jain-Kang [corrected to Jiang, Jian-Kang]; Vanden Heiden, Matthew [corrected to Vander Heiden, Matthew]. Cell Metab. 2015 Feb 3;21(2):347.


Circadian clock proteins and immunity.

Curtis AM, Bellet MM, Sassone-Corsi P, O'Neill LA.

Immunity. 2014 Feb 20;40(2):178-86. doi: 10.1016/j.immuni.2014.02.002. Review.


Knitting up the raveled sleave of care.

Yang G, Paschos G, Curtis AM, Musiek ES, McLoughlin SC, FitzGerald GA.

Sci Transl Med. 2013 Nov 20;5(212):212rv3. doi: 10.1126/scitranslmed.3007225. Review.


Endothelial microparticles: sophisticated vesicles modulating vascular function.

Curtis AM, Edelberg J, Jonas R, Rogers WT, Moore JS, Syed W, Mohler ER 3rd.

Vasc Med. 2013 Aug;18(4):204-14. doi: 10.1177/1358863X13499773. Epub 2013 Jul 26. Review.


Use of genetic tests among neurologists and psychiatrists: knowledge, attitudes, behaviors, and needs for training.

Salm M, Abbate K, Appelbaum P, Ottman R, Chung W, Marder K, Leu CS, Alcalay R, Goldman J, Curtis AM, Leech C, Taber KJ, Klitzman R.

J Genet Couns. 2014 Apr;23(2):156-63. doi: 10.1007/s10897-013-9624-0. Epub 2013 Jun 21.


A program to provide resources and support for clinical associates.

Hunt CW, Curtis AM, Sanderson BK.

J Contin Educ Nurs. 2013 Jun;44(6):269-73. doi: 10.3928/00220124-20130402-27. Epub 2013 Apr 9.


Succinate is an inflammatory signal that induces IL-1β through HIF-1α.

Tannahill GM, Curtis AM, Adamik J, Palsson-McDermott EM, McGettrick AF, Goel G, Frezza C, Bernard NJ, Kelly B, Foley NH, Zheng L, Gardet A, Tong Z, Jany SS, Corr SC, Haneklaus M, Caffrey BE, Pierce K, Walmsley S, Beasley FC, Cummins E, Nizet V, Whyte M, Taylor CT, Lin H, Masters SL, Gottlieb E, Kelly VP, Clish C, Auron PE, Xavier RJ, O'Neill LA.

Nature. 2013 Apr 11;496(7444):238-42. doi: 10.1038/nature11986. Epub 2013 Mar 24.


Platelet microRNAs: Novy Mir* or mired in human complexity?

Curtis AM, FitzGerald GA.

Circ Res. 2013 Feb 15;112(4):576-8. doi: 10.1161/CIRCRESAHA.113.300859. No abstract available.


Recognizing nurse stakeholder dissonance as a critical determinant of patient safety in new healthcare information technologies.

Samaras EA, Real SD, Curtis AM, Meunier TS.

Work. 2012;41 Suppl 1:1904-10. doi: 10.3233/WOR-2012-0406-1904.


Relationship of microparticles to progenitor cells as a measure of vascular health in a diabetic population.

Curtis AM, Zhang L, Medenilla E, Gui M, Wilkinson PF, Hu E, Giri J, Doraiswamy V, Gunda S, Burgert ME, Moore JS, Edelberg JM, Mohler ER 3rd.

Cytometry B Clin Cytom. 2010 Sep;78(5):329-37. doi: 10.1002/cyto.b.20528. Epub 2010 Jun 11.


Long-term follow-up of beryllium sensitized workers from a single employer.

Duggal M, Deubner DC, Curtis AM, Cullen MR.

BMC Public Health. 2010 Jan 4;10:5. doi: 10.1186/1471-2458-10-5.


p38 mitogen-activated protein kinase targets the production of proinflammatory endothelial microparticles.

Curtis AM, Wilkinson PF, Gui M, Gales TL, Hu E, Edelberg JM.

J Thromb Haemost. 2009 Apr;7(4):701-9. doi: 10.1111/j.1538-7836.2009.03304.x. Epub 2009 Jan 22.


WAVECLOCK: wavelet analysis of circadian oscillation.

Price TS, Baggs JE, Curtis AM, Fitzgerald GA, Hogenesch JB.

Bioinformatics. 2008 Dec 1;24(23):2794-5. doi: 10.1093/bioinformatics/btn521. Epub 2008 Oct 17.


Peripheral circadian clock rhythmicity is retained in the absence of adrenergic signaling.

Reilly DF, Curtis AM, Cheng Y, Westgate EJ, Rudic RD, Paschos G, Morris J, Ouyang M, Thomas SA, FitzGerald GA.

Arterioscler Thromb Vasc Biol. 2008 Jan;28(1):121-6. Epub 2007 Nov 1.


Central and peripheral clocks in cardiovascular and metabolic function.

Curtis AM, Fitzgerald GA.

Ann Med. 2006;38(8):552-9. Review.


Circadian variation of blood pressure and the vascular response to asynchronous stress.

Curtis AM, Cheng Y, Kapoor S, Reilly D, Price TS, Fitzgerald GA.

Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3450-5. Epub 2007 Feb 20.


Genomic organization of the rat Clock gene and sequence analysis in inbred rat strains.

Woon PY, Curtis AM, Kaisaki PJ, Argoud K, Wallace KJ, Bihoreau MT, FitzGerald GA, Gauguier D.

Genomics. 2006 Feb;87(2):208-17. Epub 2006 Jan 11.


Bioinformatic analysis of circadian gene oscillation in mouse aorta.

Rudic RD, McNamara P, Reilly D, Grosser T, Curtis AM, Price TS, Panda S, Hogenesch JB, FitzGerald GA.

Circulation. 2005 Oct 25;112(17):2716-24. Epub 2005 Oct 17.


Peripheral clocks and the regulation of cardiovascular and metabolic function.

Rudic RD, Curtis AM, Cheng Y, FitzGerald G.

Methods Enzymol. 2005;393:524-39.


BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis.

Rudic RD, McNamara P, Curtis AM, Boston RC, Panda S, Hogenesch JB, Fitzgerald GA.

PLoS Biol. 2004 Nov;2(11):e377. Epub 2004 Nov 2.


Histone acetyltransferase-dependent chromatin remodeling and the vascular clock.

Curtis AM, Seo SB, Westgate EJ, Rudic RD, Smyth EM, Chakravarti D, FitzGerald GA, McNamara P.

J Biol Chem. 2004 Feb 20;279(8):7091-7. Epub 2003 Nov 26.


Association of NOD2 with Crohn's disease in a homogenous Irish population.

Bairead E, Harmon DL, Curtis AM, Kelly Y, O'Leary C, Gardner M, Leahy DT, Vaughan P, Keegan D, O'Morain C, O'Donoghue D, Shanahan F, Parfrey NA, Quane KA.

Eur J Hum Genet. 2003 Mar;11(3):237-44.


Pulmonary disease from nontuberculous mycobacteria in patients with human immunodeficiency virus.

Rigsby MO, Curtis AM.

Chest. 1994 Sep;106(3):913-9. Review. No abstract available.


Role of computed tomography in the staging of primary melanoma.

Buzaid AC, Sandler AB, Mani S, Curtis AM, Poo WJ, Bolognia JL, Ariyan S.

J Clin Oncol. 1993 Apr;11(4):638-43.


Metastatic disease to the chest in patients with extrathoracic malignancy.

Coppage L, Shaw C, Curtis AM.

J Thorac Imaging. 1987 Oct;2(4):24-37. Review.


Adult-onset pulmonary tuberculosis.

Choyke PL, Sostman HD, Curtis AM, Ravin CE, Chen JT, Godwin JD, Putman CE.

Radiology. 1983 Aug;148(2):357-62.


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