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Items: 36


Adrenal serotonin derives from accumulation by the antidepressant-sensitive serotonin transporter.

Brindley RL, Bauer MB, Walker LA, Quinlan MA, Carneiro AMD, Sze JY, Blakely RD, Currie KPM.

Pharmacol Res. 2019 Feb;140:56-66. doi: 10.1016/j.phrs.2018.06.008. Epub 2018 Jun 9.


Sigma-1 receptor ligands inhibit catecholamine secretion from adrenal chromaffin cells due to block of nicotinic acetylcholine receptors.

Brindley RL, Bauer MB, Hartley ND, Horning KJ, Currie KPM.

J Neurochem. 2017 Oct;143(2):171-182. doi: 10.1111/jnc.14149. Epub 2017 Sep 19.


Gβγ directly modulates vesicle fusion by competing with synaptotagmin for binding to neuronal SNARE proteins embedded in membranes.

Zurawski Z, Page B, Chicka MC, Brindley RL, Wells CA, Preininger AM, Hyde K, Gilbert JA, Cruz-Rodriguez O, Currie KPM, Chapman ER, Alford S, Hamm HE.

J Biol Chem. 2017 Jul 21;292(29):12165-12177. doi: 10.1074/jbc.M116.773523. Epub 2017 May 17.


Serotonin and Serotonin Transporters in the Adrenal Medulla: A Potential Hub for Modulation of the Sympathetic Stress Response.

Brindley RL, Bauer MB, Blakely RD, Currie KPM.

ACS Chem Neurosci. 2017 May 17;8(5):943-954. doi: 10.1021/acschemneuro.7b00026. Epub 2017 Apr 13. Review.


NaV-igating the MAP from PACAP to excitement. Focus on "Activation of MEK/ERK signaling contributes to the PACAP-induced increase in guinea pig cardiac neuron excitability".

Currie KP.

Am J Physiol Cell Physiol. 2016 Oct 1;311(4):C641-C642. doi: 10.1152/ajpcell.00270.2016. Epub 2016 Sep 21. No abstract available.


An interplay between the serotonin transporter (SERT) and 5-HT receptors controls stimulus-secretion coupling in sympathoadrenal chromaffin cells.

Brindley RL, Bauer MB, Blakely RD, Currie KPM.

Neuropharmacology. 2016 Nov;110(Pt A):438-448. doi: 10.1016/j.neuropharm.2016.08.015. Epub 2016 Aug 18.


"Slow" Voltage-Dependent Inactivation of CaV2.2 Calcium Channels Is Modulated by the PKC Activator Phorbol 12-Myristate 13-Acetate (PMA).

Zhu L, McDavid S, Currie KP.

PLoS One. 2015 Jul 29;10(7):e0134117. doi: 10.1371/journal.pone.0134117. eCollection 2015.


Butanol isomers exert distinct effects on voltage-gated calcium channel currents and thus catecholamine secretion in adrenal chromaffin cells.

McDavid S, Bauer MB, Brindley RL, Jewell ML, Currie KP.

PLoS One. 2014 Oct 2;9(10):e109203. doi: 10.1371/journal.pone.0109203. eCollection 2014.


A microfluidic platform for chemical stimulation and real time analysis of catecholamine secretion from neuroendocrine cells.

Ges IA, Brindley RL, Currie KP, Baudenbacher FJ.

Lab Chip. 2013 Dec 7;13(23):4663-73. doi: 10.1039/c3lc50779c.


Regulation of Ca(V)2 calcium channels by G protein coupled receptors.

Zamponi GW, Currie KP.

Biochim Biophys Acta. 2013 Jul;1828(7):1629-43. doi: 10.1016/j.bbamem.2012.10.004. Epub 2012 Oct 12. Review.


Gabapentin inhibits catecholamine release from adrenal chromaffin cells.

Todd RD, McDavid SM, Brindley RL, Jewell ML, Currie KP.

Anesthesiology. 2012 May;116(5):1013-24. doi: 10.1097/ALN.0b013e31825153ea.


Electrochemical detection of catecholamine release using planar iridium oxide electrodes in nanoliter microfluidic cell culture volumes.

Ges IA, Currie KP, Baudenbacher F.

Biosens Bioelectron. 2012 Apr 15;34(1):30-6. doi: 10.1016/j.bios.2011.11.050. Epub 2011 Dec 22.


Regulation of calcium channels and exocytosis in mouse adrenal chromaffin cells by prostaglandin EP3 receptors.

Jewell ML, Breyer RM, Currie KP.

Mol Pharmacol. 2011 Jun;79(6):987-96. doi: 10.1124/mol.110.068569. Epub 2011 Mar 7.


G protein modulation of CaV2 voltage-gated calcium channels.

Currie KP.

Channels (Austin). 2010 Nov-Dec;4(6):497-509. Epub 2010 Nov 1. Review.


Inhibition of Ca2+ channels and adrenal catecholamine release by G protein coupled receptors.

Currie KP.

Cell Mol Neurobiol. 2010 Nov;30(8):1201-8. doi: 10.1007/s10571-010-9596-7. Review.


G protein betagamma subunits modulate the number and nature of exocytotic fusion events in adrenal chromaffin cells independent of calcium entry.

Yoon EJ, Hamm HE, Currie KP.

J Neurophysiol. 2008 Nov;100(5):2929-39. doi: 10.1152/jn.90839.2008. Epub 2008 Sep 24.


N- and P/Q-type Ca2+ channels in adrenal chromaffin cells.

Fox AP, Cahill AL, Currie KP, Grabner C, Harkins AB, Herring B, Hurley JH, Xie Z.

Acta Physiol (Oxf). 2008 Feb;192(2):247-61. Epub 2007 Nov 16. Review.


G-proteins modulate cumulative inactivation of N-type (Cav2.2) calcium channels.

McDavid S, Currie KP.

J Neurosci. 2006 Dec 20;26(51):13373-83.


Etomidate elevates intracellular calcium levels and promotes catecholamine secretion in bovine chromaffin cells.

Xie Z, Currie KP, Fox AP.

J Physiol. 2004 Nov 1;560(Pt 3):677-90. Epub 2004 Aug 26.


Role of Cl- co-transporters in the excitation produced by GABAA receptors in juvenile bovine adrenal chromaffin cells.

Xie Z, Currie KP, Cahill AL, Fox AP.

J Neurophysiol. 2003 Dec;90(6):3828-37. Epub 2003 Sep 10.


A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin.

Zhou YP, Sreenan S, Pan CY, Currie KP, Bindokas VP, Horikawa Y, Lee JP, Ostrega D, Ahmed N, Baldwin AC, Cox NJ, Fox AP, Miller RJ, Bell GI, Polonsky KS.

Metabolism. 2003 May;52(5):528-34.


Cause for excite-M-ent in adrenal chromaffin cells.

Currie KP, Fox AP.

J Physiol. 2002 May 1;540(Pt 3):729. No abstract available.


Calpains play a role in insulin secretion and action.

Sreenan SK, Zhou YP, Otani K, Hansen PA, Currie KP, Pan CY, Lee JP, Ostrega DM, Pugh W, Horikawa Y, Cox NJ, Hanis CL, Burant CF, Fox AP, Bell GI, Polonsky KS.

Diabetes. 2001 Sep;50(9):2013-20.


The role of dynamic palmitoylation in Ca2+ channel inactivation.

Hurley JH, Cahill AL, Currie KP, Fox AP.

Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):9293-8.


Aspects of calcium-activated chloride currents: a neuronal perspective.

Scott RH, Sutton KG, Griffin A, Stapleton SR, Currie KP.

Pharmacol Ther. 1995 Jun;66(3):535-65. Review.


Palmitoyl-DL-carnitine has calcium-dependent effects on cultured neurones from rat dorsal root ganglia.

Stapleton SR, Currie KP, Scott RH, Bell BA.

Br J Pharmacol. 1992 Dec;107(4):1192-7.


Calcium-activated currents in cultured neurones from rat dorsal root ganglia.

Currie KP, Scott RH.

Br J Pharmacol. 1992 Jul;106(3):593-602.


Modulation of neuronal Ca(2+)-dependent currents by neurotransmitters, G-proteins and toxins.

Scott RH, Currie KP, Sutton KG, Dolphin AC.

Biochem Soc Trans. 1992 May;20(2):443-9. No abstract available.


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