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Items: 43


Cyclic AMP in human preterm infant blood is associated with increased TLR-mediated production of acute-phase and anti-inflammatory cytokines in vitro.

Strunk T, van Haren SD, Hibbert J, Pettengill M, Ozonoff A, Jans J, Schüller SS, Burgner D, Levy O, Currie AJ.

Pediatr Res. 2019 Oct 2. doi: 10.1038/s41390-019-0586-2. [Epub ahead of print]


Exposure to the antimicrobial peptide LL-37 produces dendritic cells optimized for immunotherapy.

Findlay EG, Currie AJ, Zhang A, Ovciarikova J, Young L, Stevens H, McHugh BJ, Canel M, Gray M, Milling SWF, Campbell JDM, Savill J, Serrels A, Davidson DJ.

Oncoimmunology. 2019 May 1;8(8):1608106. doi: 10.1080/2162402X.2019.1608106. eCollection 2019.


Effect of exercise on acute postprandial glucose concentrations and interleukin-6 responses in sedentary and overweight males.

Raman A, Peiffer JJ, Hoyne GF, Lawler NG, Currie AJ, Fairchild TJ.

Appl Physiol Nutr Metab. 2018 Dec;43(12):1298-1306. doi: 10.1139/apnm-2018-0160. Epub 2018 Jun 1.


Evidence of functional cell-mediated immune responses to nontypeable Haemophilus influenzae in otitis-prone children.

Seppanen E, Tan D, Corscadden KJ, Currie AJ, Richmond PC, Thornton RB, Kirkham LS.

PLoS One. 2018 Apr 5;13(4):e0193962. doi: 10.1371/journal.pone.0193962. eCollection 2018.


Exposure to chorioamnionitis alters the monocyte transcriptional response to the neonatal pathogen Staphylococcus epidermidis.

de Jong E, Hancock DG, Wells C, Richmond P, Simmer K, Burgner D, Strunk T, Currie AJ.

Immunol Cell Biol. 2018 Sep;96(8):792-804. doi: 10.1111/imcb.12037. Epub 2018 Apr 23.


The Western environment reduces innate immune cytokine production in Chinese immigrants.

Saiganesh A, Hales BJ, Chen S, Filipovska-Naumovska E, Pereira G, Garand M, Kollmann TR, Currie AJ, Le Souëf PN, Zhang G.

J Allergy Clin Immunol. 2018 Apr;141(4):1504-1507.e3. doi: 10.1016/j.jaci.2017.11.031. Epub 2017 Dec 21. No abstract available.


Identification of generic and pathogen-specific cord blood monocyte transcriptomes reveals a largely conserved response in preterm and term newborn infants.

de Jong E, Hancock DG, Hibbert J, Wells C, Richmond P, Simmer K, Burgner D, Strunk T, Currie AJ.

J Mol Med (Berl). 2018 Feb;96(2):147-157. doi: 10.1007/s00109-017-1609-2. Epub 2017 Nov 13.


T-cell responses against rhinovirus species A and C in asthmatic and healthy children.

Gaido CM, Granland C, Laing IA, Souëf PNL, Thomas WR, Currie AJ, Hales BJ.

Immun Inflamm Dis. 2018 Mar;6(1):143-153. doi: 10.1002/iid3.206. Epub 2017 Nov 10.


Human Infant Memory B Cell and CD4+ T Cell Responses to HibMenCY-TT Glyco-Conjugate Vaccine.

Fuery A, Richmond PC, Currie AJ.

PLoS One. 2015 Jul 20;10(7):e0133126. doi: 10.1371/journal.pone.0133126. eCollection 2015.


Restoration of defective cross-presentation in tumors by gemcitabine.

McDonnell AM, Joost Lesterhuis W, Khong A, Nowak AK, Lake RA, Currie AJ, Robinson BW.

Oncoimmunology. 2015 Feb 25;4(5):e1005501. eCollection 2015 May.


Antimicrobial protein and Peptide concentrations and activity in human breast milk consumed by preterm infants at risk of late-onset neonatal sepsis.

Trend S, Strunk T, Hibbert J, Kok CH, Zhang G, Doherty DA, Richmond P, Burgner D, Simmer K, Davidson DJ, Currie AJ.

PLoS One. 2015 Feb 2;10(2):e0117038. doi: 10.1371/journal.pone.0117038. eCollection 2015.


The efficacy of tumor debulking surgery is improved by adjuvant immunotherapy using imiquimod and anti-CD40.

Khong A, Cleaver AL, Fahmi Alatas M, Wylie BC, Connor T, Fisher SA, Broomfield S, Lesterhuis WJ, Currie AJ, Lake RA, Robinson BW.

BMC Cancer. 2014 Dec 17;14:969. doi: 10.1186/1471-2407-14-969.


Tumor-infiltrating dendritic cells exhibit defective cross-presentation of tumor antigens, but is reversed by chemotherapy.

McDonnell AM, Lesterhuis WJ, Khong A, Nowak AK, Lake RA, Currie AJ, Robinson BW.

Eur J Immunol. 2015 Jan;45(1):49-59. doi: 10.1002/eji.201444722. Epub 2014 Dec 15.


NOD1 and NOD2 expression and function in very preterm infant mononuclear cells.

Granland C, Strunk T, Hibbert J, Prosser A, Simmer K, Burgner D, Richmond P, Currie AJ.

Acta Paediatr. 2014 May;103(5):e212-8. doi: 10.1111/apa.12559. Epub 2014 Feb 7.


A practical method for preparation of pneumococcal and nontypeable Haemophilus influenzae inocula that preserves viability and immunostimulatory activity.

Kirkham LA, Corscadden KJ, Wiertsema SP, Currie AJ, Richmond PC.

BMC Res Notes. 2013 Dec 9;6:522. doi: 10.1186/1756-0500-6-522.


Agonistic anti-CD40 antibody therapy is effective against postoperative cancer recurrence and metastasis in a murine tumor model.

Khong A, Brown MD, Vivian JB, Robinson BW, Currie AJ.

J Immunother. 2013 Sep;36(7):365-72. doi: 10.1097/CJI.0b013e31829fb856.


Loss of antigen cross-presentation after complete tumor resection is associated with the generation of protective tumor-specific CD8(+) T-cell immunity.

Brown MD, van der Most R, Vivian JB, Lake RA, Larma I, Robinson BW, Currie AJ.

Oncoimmunology. 2012 Oct 1;1(7):1084-1094.


Tumor cells, rather than dendritic cells, deliver antigen to the lymph node for cross-presentation.

McDonnell AM, Currie AJ, Brown M, Kania K, Wylie B, Cleaver A, Lake R, Robinson BW.

Oncoimmunology. 2012 Sep 1;1(6):840-846.


Trivalent influenza vaccine and febrile adverse events in Australia, 2010: clinical features and potential mechanisms.

Blyth CC, Currie AJ, Wiertsema SP, Conway N, Kirkham LA, Fuery A, Mascaro F, Geelhoed GC, Richmond PC.

Vaccine. 2011 Jul 18;29(32):5107-13. doi: 10.1016/j.vaccine.2011.05.054. Epub 2011 Jun 1.


Preterm infants have deficient monocyte and lymphocyte cytokine responses to group B streptococcus.

Currie AJ, Curtis S, Strunk T, Riley K, Liyanage K, Prescott S, Doherty D, Simmer K, Richmond P, Burgner D.

Infect Immun. 2011 Apr;79(4):1588-96. doi: 10.1128/IAI.00535-10. Epub 2011 Feb 7.


Tumor antigen cross-presentation and the dendritic cell: where it all begins?

McDonnell AM, Robinson BW, Currie AJ.

Clin Dev Immunol. 2010;2010:539519. doi: 10.1155/2010/539519. Epub 2010 Oct 13.


TLR2 mediates recognition of live Staphylococcus epidermidis and clearance of bacteremia.

Strunk T, Power Coombs MR, Currie AJ, Richmond P, Golenbock DT, Stoler-Barak L, Gallington LC, Otto M, Burgner D, Levy O.

PLoS One. 2010 Apr 9;5(4):e10111. doi: 10.1371/journal.pone.0010111.


CD8alpha+ DC are not the sole subset cross-presenting cell-associated tumor antigens from a solid tumor.

McDonnell AM, Prosser AC, van Bruggen I, Robinson BW, Currie AJ.

Eur J Immunol. 2010 Jun;40(6):1617-27. doi: 10.1002/eji.200940153.


Dual control of antitumor CD8 T cells through the programmed death-1/programmed death-ligand 1 pathway and immunosuppressive CD4 T cells: regulation and counterregulation.

Currie AJ, Prosser A, McDonnell A, Cleaver AL, Robinson BW, Freeman GJ, van der Most RG.

J Immunol. 2009 Dec 15;183(12):7898-908. doi: 10.4049/jimmunol.0901060.


Cyclophosphamide chemotherapy sensitizes tumor cells to TRAIL-dependent CD8 T cell-mediated immune attack resulting in suppression of tumor growth.

van der Most RG, Currie AJ, Cleaver AL, Salmons J, Nowak AK, Mahendran S, Larma I, Prosser A, Robinson BW, Smyth MJ, Scalzo AA, Degli-Esposti MA, Lake RA.

PLoS One. 2009 Sep 10;4(9):e6982. doi: 10.1371/journal.pone.0006982.


Locally administered TLR7 agonists drive systemic antitumor immune responses that are enhanced by anti-CD40 immunotherapy.

Broomfield SA, van der Most RG, Prosser AC, Mahendran S, Tovey MG, Smyth MJ, Robinson BW, Currie AJ.

J Immunol. 2009 May 1;182(9):5217-24. doi: 10.4049/jimmunol.0803826.


Tumor eradication after cyclophosphamide depends on concurrent depletion of regulatory T cells: a role for cycling TNFR2-expressing effector-suppressor T cells in limiting effective chemotherapy.

van der Most RG, Currie AJ, Mahendran S, Prosser A, Darabi A, Robinson BW, Nowak AK, Lake RA.

Cancer Immunol Immunother. 2009 Aug;58(8):1219-28. doi: 10.1007/s00262-008-0628-9. Epub 2008 Dec 4.


Targeting the effector site with IFN-alphabeta-inducing TLR ligands reactivates tumor-resident CD8 T cell responses to eradicate established solid tumors.

Currie AJ, van der Most RG, Broomfield SA, Prosser AC, Tovey MG, Robinson BW.

J Immunol. 2008 Feb 1;180(3):1535-44.


Decoding dangerous death: how cytotoxic chemotherapy invokes inflammation, immunity or nothing at all.

van der Most RG, Currie AJ, Robinson BW, Lake RA.

Cell Death Differ. 2008 Jan;15(1):13-20. Epub 2007 Nov 16. Review.


Prevalence of Toll-like receptor signalling defects in apparently healthy children who developed invasive pneumococcal infection.

Hirschfeld AF, Bettinger JA, Victor RE, Davidson DJ, Currie AJ, Ansermino JM, Scheifele DW, Orange JS, Turvey SE.

Clin Immunol. 2007 Mar;122(3):271-8. Epub 2006 Dec 6.


IRAK-4 mutation (Q293X): rapid detection and characterization of defective post-transcriptional TLR/IL-1R responses in human myeloid and non-myeloid cells.

Davidson DJ, Currie AJ, Bowdish DM, Brown KL, Rosenberger CM, Ma RC, Bylund J, Campsall PA, Puel A, Picard C, Casanova JL, Turvey SE, Hancock RE, Devon RS, Speert DP.

J Immunol. 2006 Dec 1;177(11):8202-11.


Pseudomonas aeruginosa: role in the pathogenesis of the CF lung lesion.

Currie AJ, Speert DP, Davidson DJ.

Semin Respir Crit Care Med. 2003 Dec;24(6):671-80.


Letting the CAThelicidin out of the bag, as a therapeutic modulator of the adaptive immune system.

Davidson DJ, Currie AJ.

Leuk Res. 2005 May;29(5):477-9. Epub 2005 Jan 23. No abstract available.


Primary immunodeficiency to pneumococcal infection due to a defect in Toll-like receptor signaling.

Currie AJ, Davidson DJ, Reid GS, Bharya S, MacDonald KL, Devon RS, Speert DP.

J Pediatr. 2004 Apr;144(4):512-8.


AICA riboside both activates AMP-activated protein kinase and competes with adenosine for the nucleoside transporter in the CA1 region of the rat hippocampus.

Gadalla AE, Pearson T, Currie AJ, Dale N, Hawley SA, Sheehan M, Hirst W, Michel AD, Randall A, Hardie DG, Frenguelli BG.

J Neurochem. 2004 Mar;88(5):1272-82.


Plasticity of purine release during cerebral ischemia: clinical implications?

Pearson T, Currie AJ, Etherington LA, Gadalla AE, Damian K, Llaudet E, Dale N, Frenguelli BG.

J Cell Mol Med. 2003 Oct-Dec;7(4):362-75. Review.


The cationic antimicrobial peptide LL-37 modulates dendritic cell differentiation and dendritic cell-induced T cell polarization.

Davidson DJ, Currie AJ, Reid GS, Bowdish DM, MacDonald KL, Ma RC, Hancock RE, Speert DP.

J Immunol. 2004 Jan 15;172(2):1146-56. Erratum in: J Immunol. 2004 Feb 15;172(4):following 2703.


Crossing the pain barrier: P2 receptors as targets for novel analgesics.

Kennedy C, Assis TS, Currie AJ, Rowan EG.

J Physiol. 2003 Dec 15;553(Pt 3):683-94. Epub 2003 Sep 26. Review.


Nitric oxide production by alveolar macrophages in response to house dust mite fecal pellets and the mite allergens, Der p 1 and Der p 2.

Peake HL, Currie AJ, Stewart GA, McWilliam AS.

J Allergy Clin Immunol. 2003 Sep;112(3):531-7.


Neonatal screening for congenital adrenal hyperplasia: a programme based on a novel direct radioimmunoassay for 17-hydroxyprogesterone in blood spots.

Wallace AM, Beastall GH, Cook B, Currie AJ, Ross AM, Kennedy R, Girdwood RW.

J Endocrinol. 1986 Feb;108(2):299-308.


Human placental receptors for luteinizing hormone releasing hormone.

Currie AJ, Fraser HM, Sharpe RM.

Biochem Biophys Res Commun. 1981 Mar 16;99(1):332-8. No abstract available.


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