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Items: 37

1.

Effects of immunomodulatory drugs on depressive symptoms: A mega-analysis of randomized, placebo-controlled clinical trials in inflammatory disorders.

Wittenberg GM, Stylianou A, Zhang Y, Sun Y, Gupta A, Jagannatha PS, Wang D, Hsu B, Curran ME, Khan S; MRC ImmunoPsychiatry Consortium, Chen G, Bullmore ET, Drevets WC.

Mol Psychiatry. 2019 Aug 19. doi: 10.1038/s41380-019-0471-8. [Epub ahead of print]

PMID:
31427751
2.

Comprehensive analysis of treatment response phenotypes in rheumatoid arthritis for pharmacogenetic studies.

Standish KA, Huang CC, Curran ME, Schork NJ.

Arthritis Res Ther. 2017 May 12;19(1):90. doi: 10.1186/s13075-017-1299-8.

3.

Integrative genomic deconvolution of rheumatoid arthritis GWAS loci into gene and cell type associations.

Walsh AM, Whitaker JW, Huang CC, Cherkas Y, Lamberth SL, Brodmerkel C, Curran ME, Dobrin R.

Genome Biol. 2016 Apr 30;17:79. doi: 10.1186/s13059-016-0948-6.

4.

Group-based variant calling leveraging next-generation supercomputing for large-scale whole-genome sequencing studies.

Standish KA, Carland TM, Lockwood GK, Pfeiffer W, Tatineni M, Huang CC, Lamberth S, Cherkas Y, Brodmerkel C, Jaeger E, Smith L, Rajagopal G, Curran ME, Schork NJ.

BMC Bioinformatics. 2015 Sep 22;16:304. doi: 10.1186/s12859-015-0736-4.

5.

Modular analysis of peripheral blood gene expression in rheumatoid arthritis captures reproducible gene expression changes in tumor necrosis factor responders.

Oswald M, Curran ME, Lamberth SL, Townsend RM, Hamilton JD, Chernoff DN, Carulli J, Townsend MJ, Weinblatt ME, Kern M, Pond CM, Lee A, Gregersen PK.

Arthritis Rheumatol. 2015 Feb;67(2):344-51. doi: 10.1002/art.38947.

6.

Diagnostics and personalized medicine: observations from the World Companion Diagnostics Summit.

Curran ME, Platero S.

Pharmacogenomics. 2011 Apr;12(4):465-70. doi: 10.2217/pgs.11.9.

7.

Spectrum and prevalence of cardiac sodium channel variants among black, white, Asian, and Hispanic individuals: implications for arrhythmogenic susceptibility and Brugada/long QT syndrome genetic testing.

Ackerman MJ, Splawski I, Makielski JC, Tester DJ, Will ML, Timothy KW, Keating MT, Jones G, Chadha M, Burrow CR, Stephens JC, Xu C, Judson R, Curran ME.

Heart Rhythm. 2004 Nov;1(5):600-7.

PMID:
15851227
8.

Sudden infant death syndrome: case-control frequency differences at genes pertinent to early autonomic nervous system embryologic development.

Weese-Mayer DE, Berry-Kravis EM, Zhou L, Maher BS, Curran ME, Silvestri JM, Marazita ML.

Pediatr Res. 2004 Sep;56(3):391-5. Epub 2004 Jul 7.

PMID:
15240857
9.
10.

Idiopathic congenital central hypoventilation syndrome: analysis of genes pertinent to early autonomic nervous system embryologic development and identification of mutations in PHOX2b.

Weese-Mayer DE, Berry-Kravis EM, Zhou L, Maher BS, Silvestri JM, Curran ME, Marazita ML.

Am J Med Genet A. 2003 Dec 15;123A(3):267-78.

PMID:
14608649
11.

Stratification by CARD15 variant genotype in a genome-wide search for inflammatory bowel disease susceptibility loci.

Shaw SH, Hampe J, White R, Mathew CG, Curran ME, Schreiber S.

Hum Genet. 2003 Nov;113(6):514-21. Epub 2003 Sep 13.

PMID:
13680363
12.

Sudden infant death syndrome: association with a promoter polymorphism of the serotonin transporter gene.

Weese-Mayer DE, Berry-Kravis EM, Maher BS, Silvestri JM, Curran ME, Marazita ML.

Am J Med Genet A. 2003 Mar 15;117A(3):268-74.

PMID:
12599191
13.

Sex stratification of an inflammatory bowel disease genome search shows male-specific linkage to the HLA region of chromosome 6.

Fisher SA, Hampe J, Macpherson AJ, Forbes A, Lennard-Jones JE, Schreiber S, Curran ME, Mathew CG, Lewis CM.

Eur J Hum Genet. 2002 Apr;10(4):259-65.

14.

Direct activation of an inwardly rectifying potassium channel by arachidonic acid.

Liu Y, Liu D, Heath L, Meyers DM, Krafte DS, Wagoner PK, Silvia CP, Yu W, Curran ME.

Mol Pharmacol. 2001 May;59(5):1061-8.

PMID:
11306688
15.

Fine mapping of the chromosome 3p susceptibility locus in inflammatory bowel disease.

Hampe J, Lynch NJ, Daniels S, Bridger S, Macpherson AJ, Stokkers P, Forbes A, Lennard-Jones JE, Mathew CG, Curran ME, Schreiber S.

Gut. 2001 Feb;48(2):191-7.

16.

Genome screen for QTLs contributing to normal variation in bone mineral density and osteoporosis.

Koller DL, Econs MJ, Morin PA, Christian JC, Hui SL, Parry P, Curran ME, Rodriguez LA, Conneally PM, Joslyn G, Peacock M, Johnston CC, Foroud T.

J Clin Endocrinol Metab. 2000 Sep;85(9):3116-20.

PMID:
10999795
17.

Analysis of single-nucleotide polymorphisms in the interleukin-4 receptor gene for association with inflammatory bowel disease.

Olavesen MG, Hampe J, Mirza MM, Saiz R, Lewis CM, Bridger S, Teare D, Easton DF, Herrmann T, Scott G, Hirst J, Sanderson J, Hodgson SV, Lee J, MacPherson A, Schreiber S, Lennard-Jones JE, Curran ME, Mathew CG.

Immunogenetics. 2000 Jan;51(1):1-7.

PMID:
10663555
18.

Linkage of inflammatory bowel disease to human chromosome 6p.

Hampe J, Shaw SH, Saiz R, Leysens N, Lantermann A, Mascheretti S, Lynch NJ, MacPherson AJ, Bridger S, van Deventer S, Stokkers P, Morin P, Mirza MM, Forbes A, Lennard-Jones JE, Mathew CG, Curran ME, Schreiber S.

Am J Hum Genet. 1999 Dec;65(6):1647-55.

19.

A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort.

Hampe J, Schreiber S, Shaw SH, Lau KF, Bridger S, Macpherson AJ, Cardon LR, Sakul H, Harris TJ, Buckler A, Hall J, Stokkers P, van Deventer SJ, N├╝rnberg P, Mirza MM, Lee JC, Lennard-Jones JE, Mathew CG, Curran ME.

Am J Hum Genet. 1999 Mar;64(3):808-16.

20.

Potassium ion channels and human disease: phenotypes to drug targets?

Curran ME.

Curr Opin Biotechnol. 1998 Dec;9(6):565-72. Review.

PMID:
9889143
21.

Linkage of a QTL contributing to normal variation in bone mineral density to chromosome 11q12-13.

Koller DL, Rodriguez LA, Christian JC, Slemenda CW, Econs MJ, Hui SL, Morin P, Conneally PM, Joslyn G, Curran ME, Peacock M, Johnston CC, Foroud T.

J Bone Miner Res. 1998 Dec;13(12):1903-8.

22.

Genetic analysis of inflammatory bowel disease in a large European cohort supports linkage to chromosomes 12 and 16.

Curran ME, Lau KF, Hampe J, Schreiber S, Bridger S, Macpherson AJ, Cardon LR, Sakul H, Harris TJ, Stokkers P, Van Deventer SJ, Mirza M, Raedler A, Kruis W, Meckler U, Theuer D, Herrmann T, Gionchetti P, Lee J, Mathew C, Lennard-Jones J.

Gastroenterology. 1998 Nov;115(5):1066-71.

PMID:
9797359
23.

Genomic localization of the human gene for KCNA10, a cGMP-activated K channel.

Orias M, Bray-Ward P, Curran ME, Keating MT, Desir GV.

Genomics. 1997 May 15;42(1):33-7.

PMID:
9177773
24.

Single HERG delayed rectifier K+ channels expressed in Xenopus oocytes.

Zou A, Curran ME, Keating MT, Sanguinetti MC.

Am J Physiol. 1997 Mar;272(3 Pt 2):H1309-14.

PMID:
9087606
25.

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel.

Sanguinetti MC, Curran ME, Zou A, Shen J, Spector PS, Atkinson DL, Keating MT.

Nature. 1996 Nov 7;384(6604):80-3.

PMID:
8900283
26.

Fast inactivation causes rectification of the IKr channel.

Spector PS, Curran ME, Zou A, Keating MT, Sanguinetti MC.

J Gen Physiol. 1996 May;107(5):611-9.

27.

Spectrum of HERG K+-channel dysfunction in an inherited cardiac arrhythmia.

Sanguinetti MC, Curran ME, Spector PS, Keating MT.

Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):2208-12. Erratum in: Proc Natl Acad Sci U S A 1996 Aug 6;93(16):8796.

28.
29.

Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias.

Wang Q, Curran ME, Splawski I, Burn TC, Millholland JM, VanRaay TJ, Shen J, Timothy KW, Vincent GM, de Jager T, Schwartz PJ, Toubin JA, Moss AJ, Atkinson DL, Landes GM, Connors TD, Keating MT.

Nat Genet. 1996 Jan;12(1):17-23.

PMID:
8528244
30.
31.

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome.

Curran ME, Splawski I, Timothy KW, Vincent GM, Green ED, Keating MT.

Cell. 1995 Mar 10;80(5):795-803.

32.

Molecular characterization and refined genomic localization of three human potassium ion channel genes.

Landes GM, Curran ME, Keating MT.

Cytogenet Cell Genet. 1995;70(3-4):280-4.

PMID:
7789190
33.

Dinucleotide repeat polymorphism at the KCNA5 locus.

Phromchotikul T, Browne DL, Curran ME, Keating MT, Litt M.

Hum Mol Genet. 1993 Sep;2(9):1512. No abstract available.

PMID:
8242092
34.

The elastin gene is disrupted by a translocation associated with supravalvular aortic stenosis.

Curran ME, Atkinson DL, Ewart AK, Morris CA, Leppert MF, Keating MT.

Cell. 1993 Apr 9;73(1):159-68.

PMID:
8096434
35.

Molecular cloning, characterization, and genomic localization of a human potassium channel gene.

Curran ME, Landes GM, Keating MT.

Genomics. 1992 Apr;12(4):729-37.

PMID:
1349297
36.

Sequence analysis of the D7S8 locus.

Curran ME, Landes GM, Leverone B, White GA, Lerner TJ.

Nucleic Acids Res. 1989 Sep 25;17(18):7534. No abstract available.

37.

Sequence of a transcribed Physarum genomic DNA fragment containing a cluster of different U-RNA sequences.

Curran ME, Sullivan DS, Arn EA, Skinner HB, Retter MW, Adams DS.

Nucleic Acids Res. 1988 Oct 25;16(20):9867. No abstract available.

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