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Items: 1 to 50 of 74

1.

Monte Carlo Simulations of Heat Deposition During Photothermal Skin Cancer Therapy Using Nanoparticles.

Jeynes JCG, Wordingham F, Moran LJ, Curnow A, Harries TJ.

Biomolecules. 2019 Aug 5;9(8). pii: E343. doi: 10.3390/biom9080343.

2.

Regression Analysis of Protoporphyrin IX Measurements Obtained During Dermatological Photodynamic Therapy.

Tyrrell J, Paterson C, Curnow A.

Cancers (Basel). 2019 Jan 10;11(1). pii: E72. doi: 10.3390/cancers11010072.

3.

Improving in vitro photodynamic therapy through the development of a novel iron chelating aminolaevulinic acid prodrug.

Curnow A, Perry A, Wood M.

Photodiagnosis Photodyn Ther. 2019 Mar;25:157-165. doi: 10.1016/j.pdpdt.2018.12.005. Epub 2018 Dec 13.

4.

Altered cellular redox homeostasis and redox responses under standard oxygen cell culture conditions versus physioxia.

Ferguson DCJ, Smerdon GR, Harries LW, Dodd NJF, Murphy MP, Curnow A, Winyard PG.

Free Radic Biol Med. 2018 Oct;126:322-333. doi: 10.1016/j.freeradbiomed.2018.08.025. Epub 2018 Aug 22.

5.

An experimental investigation of a novel iron chelating protoporphyrin IX prodrug for the enhancement of photodynamic therapy.

Anayo L, Magnussen A, Perry A, Wood M, Curnow A.

Lasers Surg Med. 2018 Jul;50(5):552-565. doi: 10.1002/lsm.22809. Epub 2018 Mar 31.

6.

Stress and Unusual Events Exacerbate Symptoms in Menière's Disease: A Longitudinal Study.

Yeo NL, White MP, Ronan N, Whinney DJ, Curnow A, Tyrrell J.

Otol Neurotol. 2018 Jan;39(1):73-81. doi: 10.1097/MAO.0000000000001592.

PMID:
29065087
7.

Diagnosis of Chronic Intestinal Pseudo-obstruction and Megacystis by Sequencing the ACTG2 Gene.

Milunsky A, Baldwin C, Zhang X, Primack D, Curnow A, Milunsky J.

J Pediatr Gastroenterol Nutr. 2017 Oct;65(4):384-387. doi: 10.1097/MPG.0000000000001608.

8.

The hydroxypyridinone iron chelator CP94 increases methyl-aminolevulinate-based photodynamic cell killing by increasing the generation of reactive oxygen species.

Dogra Y, Ferguson DCJ, Dodd NJF, Smerdon GR, Curnow A, Winyard PG.

Redox Biol. 2016 Oct;9:90-99. doi: 10.1016/j.redox.2016.07.002. Epub 2016 Jul 7.

10.

The effects of protoporphyrin IX-induced photodynamic therapy with and without iron chelation on human squamous carcinoma cells cultured under normoxic, hypoxic and hyperoxic conditions.

Blake E, Allen J, Curnow A.

Photodiagnosis Photodyn Ther. 2013 Dec;10(4):575-82. doi: 10.1016/j.pdpdt.2013.06.006. Epub 2013 Aug 8.

PMID:
24284114
11.

The cellular and molecular carcinogenic effects of radon exposure: a review.

Robertson A, Allen J, Laney R, Curnow A.

Int J Mol Sci. 2013 Jul 5;14(7):14024-63. doi: 10.3390/ijms140714024. Review.

12.

Mutations in PDYN are not responsible for multiple system atrophy.

Fogel BL, Baker C, Curnow A, Perlman SL, Geschwind DH, Coppola G.

J Neurol. 2013 Mar;260(3):927-8. doi: 10.1007/s00415-012-6830-x. Epub 2013 Jan 25. No abstract available.

13.

The time-dependent accumulation of protoporphyrin IX fluorescence in nodular basal cell carcinoma following application of methyl aminolevulinate with an oxygen pressure injection device.

Blake E, Campbell S, Allen J, Mathew J, Helliwell P, Curnow A.

J Photochem Photobiol B. 2012 Dec 5;117:97-103. doi: 10.1016/j.jphotobiol.2012.09.002. Epub 2012 Sep 18.

PMID:
23092624
14.

Effect of an oxygen pressure injection (OPI) device on the oxygen saturation of patients during dermatological methyl aminolevulinate photodynamic therapy.

Blake E, Allen J, Thorn C, Shore A, Curnow A.

Lasers Med Sci. 2013 May;28(3):997-1005. doi: 10.1007/s10103-012-1188-y. Epub 2012 Aug 28.

PMID:
22926533
15.

Radon and skin cancer in southwest England: an ecologic study.

Wheeler BW, Allen J, Depledge MH, Curnow A.

Epidemiology. 2012 Jan;23(1):44-52. doi: 10.1097/EDE.0b013e31823b6139.

PMID:
22081061
16.

An in vitro comparison of the effects of the iron-chelating agents, CP94 and dexrazoxane, on protoporphyrin IX accumulation for photodynamic therapy and/or fluorescence guided resection.

Blake E, Allen J, Curnow A.

Photochem Photobiol. 2011 Nov-Dec;87(6):1419-26. doi: 10.1111/j.1751-1097.2011.00985.x. Epub 2011 Sep 16.

PMID:
21834866
17.

Oxygen saturation and perfusion changes during dermatological methylaminolaevulinate photodynamic therapy.

Tyrrell J, Thorn C, Shore A, Campbell S, Curnow A.

Br J Dermatol. 2011 Dec;165(6):1323-31. doi: 10.1111/j.1365-2133.2011.10554.x. Epub 2011 Nov 17.

PMID:
21801159
18.

Comparison of protoporphyrin IX accumulation and destruction during methylaminolevulinate photodynamic therapy of skin tumours located at acral and nonacral sites.

Tyrrell JS, Morton C, Campbell SM, Curnow A.

Br J Dermatol. 2011 Jun;164(6):1362-8. doi: 10.1111/j.1365-2133.2011.10265.x. Epub 2011 May 13.

PMID:
21564050
19.
20.

The effect of air cooling pain relief on protoporphyrin IX photobleaching and clinical efficacy during dermatological photodynamic therapy.

Tyrrell J, Campbell SM, Curnow A.

J Photochem Photobiol B. 2011 Apr 4;103(1):1-7. doi: 10.1016/j.jphotobiol.2010.12.011. Epub 2010 Dec 28.

PMID:
21277787
21.

Protoporphyrin IX photobleaching during the light irradiation phase of standard dermatological methyl-aminolevulinate photodynamic therapy.

Tyrrell J, Campbell S, Curnow A.

Photodiagnosis Photodyn Ther. 2010 Dec;7(4):232-8. doi: 10.1016/j.pdpdt.2010.09.005. Epub 2010 Nov 5.

PMID:
21112545
22.

An investigation into the awareness and understanding of the ultraviolet index forecasts in the South West of England.

Morris J, Laing-Morton T, Marno P, Curnow A.

Photochem Photobiol Sci. 2011 Jan;10(1):103-8. doi: 10.1039/c0pp00232a. Epub 2010 Nov 3.

PMID:
21046048
23.
24.

Effect of MAL-photodynamic therapy on hypertrophic scarring.

Campbell SM, Tyrrell J, Marshall R, Curnow A.

Photodiagnosis Photodyn Ther. 2010 Sep;7(3):183-8. doi: 10.1016/j.pdpdt.2010.07.003. Epub 2010 Aug 6.

PMID:
20728843
25.

The hydroxypyridinone iron chelator CP94 can enhance PpIX-induced PDT of cultured human glioma cells.

Blake E, Curnow A.

Photochem Photobiol. 2010 Sep-Oct;86(5):1154-60. doi: 10.1111/j.1751-1097.2010.00770.x.

PMID:
20573043
26.

Validation of a non-invasive fluorescence imaging system to monitor dermatological PDT.

Tyrrell J, Campbell S, Curnow A.

Photodiagnosis Photodyn Ther. 2010 Jun;7(2):86-97. doi: 10.1016/j.pdpdt.2010.03.002. Epub 2010 Apr 24.

PMID:
20510303
27.

Using natural dietary sources of antioxidants to protect against ultraviolet and visible radiation-induced DNA damage: an investigation of human green tea ingestion.

Malhomme de la Roche H, Seagrove S, Mehta A, Divekar P, Campbell S, Curnow A.

J Photochem Photobiol B. 2010 Nov 3;101(2):169-73. doi: 10.1016/j.jphotobiol.2010.04.006. Epub 2010 Apr 20.

PMID:
20452781
29.

12th World Congress of the International Photodynamic Association (IPA), 11-15th June 2009, Seattle, USA.

Curnow A.

Photodiagnosis Photodyn Ther. 2009 Jun;6(2):150-1. doi: 10.1016/j.pdpdt.2009.07.005. Epub 2009 Aug 7. No abstract available.

PMID:
19683217
30.

Clinical investigation of the novel iron-chelating agent, CP94, to enhance topical photodynamic therapy of nodular basal cell carcinoma.

Campbell SM, Morton CA, Alyahya R, Horton S, Pye A, Curnow A.

Br J Dermatol. 2008 Aug;159(2):387-93. doi: 10.1111/j.1365-2133.2008.08668.x. Epub 2008 Jun 9.

PMID:
18544077
31.

Extensive vulval intraepithelial neoplasia treated with a new regime of systemic photodynamic therapy using meta-tetrahydroxychlorin (Foscan).

Campbell SM, Curnow A.

J Eur Acad Dermatol Venereol. 2008 Apr;22(4):502-3. doi: 10.1111/j.1468-3083.2007.02365.x. No abstract available.

PMID:
18363917
32.
33.

A clinical investigation to determine the effect of pressure injection on the penetration of topical methyl aminolevulinate into nodular basal cell carcinoma of the skin.

Campbell SM, Pye A, Horton S, Matthew J, Helliwell P, Curnow A.

J Environ Pathol Toxicol Oncol. 2007;26(4):295-303.

PMID:
18197827
34.

Biochemical manipulation via iron chelation to enhance porphyrin production from porphyrin precursors.

Curnow A, Pye A.

J Environ Pathol Toxicol Oncol. 2007;26(2):89-103.

PMID:
17725535
36.

Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.

Evdokimov AG, Pokross M, Walter RL, Mekel M, Barnett BL, Amburgey J, Seibel WL, Soper SJ, Djung JF, Fairweather N, Diven C, Rastogi V, Grinius L, Klanke C, Siehnel R, Twinem T, Andrews R, Curnow A.

Proteins. 2007 Feb 15;66(3):538-46.

PMID:
17120228
37.
38.

UVA-induced apoptosis studied by the new apo/necro-Comet-assay which distinguishes viable, apoptotic and necrotic cells.

Morley N, Rapp A, Dittmar H, Salter L, Gould D, Greulich KO, Curnow A.

Mutagenesis. 2006 Mar;21(2):105-14. Epub 2006 Feb 24.

PMID:
16500949
39.

Hg(II) exposure exacerbates UV-induced DNA damage in MRC5 fibroblasts: a comet assay study.

Bradfield W, Pye A, Clifford T, Salter L, Gould D, Campbell S, Curnow A.

J Environ Sci Health A Tox Hazard Subst Environ Eng. 2006;41(2):143-8.

PMID:
16423720
40.

Development and validation of a whole-cell inhibition assay for bacterial methionine aminopeptidase by surface-enhanced laser desorption ionization-time of flight mass spectrometry.

Greis KD, Zhou S, Siehnel R, Klanke C, Curnow A, Howard J, Layh-Schmitt G.

Antimicrob Agents Chemother. 2005 Aug;49(8):3428-34.

41.

The green tea polyphenol (-)-epigallocatechin gallate and green tea can protect human cellular DNA from ultraviolet and visible radiation-induced damage.

Morley N, Clifford T, Salter L, Campbell S, Gould D, Curnow A.

Photodermatol Photoimmunol Photomed. 2005 Feb;21(1):15-22.

PMID:
15634219
42.

Photodynamic therapy using meta-tetrahydroxyphenylchlorin (Foscan) for the treatment of vulval intraepithelial neoplasia.

Campbell SM, Gould DJ, Salter L, Clifford T, Curnow A.

Br J Dermatol. 2004 Nov;151(5):1076-80.

PMID:
15541088
44.

N-acetyl-L-cysteine prevents DNA damage induced by UVA, UVB and visible radiation in human fibroblasts.

Morley N, Curnow A, Salter L, Campbell S, Gould D.

J Photochem Photobiol B. 2003 Dec 5;72(1-3):55-60.

PMID:
14644566
45.

Laparoscopic distal pancreatectomy for traumatic pancreatic transection.

Reynolds EM, Curnow AJ.

J Pediatr Surg. 2003 Oct;38(10):E7-9.

PMID:
14577094
46.

Optimisation of illumination for photodynamic therapy with mTHPC on normal colon and a transplantable tumour in rats.

Tsutsui H, MacRobert AJ, Curnow A, Rogowska A, Buonaccorsi G, Kato H, Bown SG.

Lasers Med Sci. 2002;17(2):101-9.

PMID:
12111593
47.

Fluorescence biodistribution and photosensitising activity of toluidine blue o on rat buccal mucosa.

Kömerik N, Curnow A, MacRobert AJ, Hopper C, Speight PM, Wilson M.

Lasers Med Sci. 2002;17(2):86-92.

PMID:
12111591
49.

Profiling of drugs for membrane activity using liposomes as an in vitro model system.

Grinius L, Stanton DT, Morris CM, Howard JM, Curnow AW.

Drug Dev Ind Pharm. 2002;28(2):193-202.

PMID:
11926363
50.

Paracetamol can exacerbate irradiation-induced DNA damage.

Curnow A, Salter L, Morley N, Campbell S, Gould D.

Br J Clin Pharmacol. 2002 Mar;53(3):338-40. No abstract available.

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