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Items: 1 to 50 of 188

1.

Calcified nodules in retinal drusen are associated with disease progression in age-related macular degeneration.

Tan ACS, Pilgrim MG, Fearn S, Bertazzo S, Tsolaki E, Morrell AP, Li M, Messinger JD, Dolz-Marco R, Lei J, Nittala MG, Sadda SR, Lengyel I, Freund KB, Curcio CA.

Sci Transl Med. 2018 Nov 7;10(466). pii: eaat4544. doi: 10.1126/scitranslmed.aat4544.

PMID:
30404862
2.

The ARMS2 A69S Polymorphism Is Associated with Delayed Rod-Mediated Dark Adaptation in Eyes at Risk for Incident Age-Related Macular Degeneration.

Mullins RF, McGwin G Jr, Searcey K, Clark ME, Kennedy EL, Curcio CA, Stone EM, Owsley C.

Ophthalmology. 2018 Oct 30. pii: S0161-6420(18)32050-5. doi: 10.1016/j.ophtha.2018.10.037. [Epub ahead of print]

PMID:
30389424
3.

Antecedents of Soft Drusen, the Specific Deposits of Age-Related Macular Degeneration, in the Biology of Human Macula.

Curcio CA.

Invest Ophthalmol Vis Sci. 2018 Mar 20;59(4):AMD182-AMD194. doi: 10.1167/iovs.18-24883. Review.

PMID:
30357337
4.

Soft Drusen in Age-Related Macular Degeneration: Biology and Targeting Via the Oil Spill Strategies.

Curcio CA.

Invest Ophthalmol Vis Sci. 2018 Mar 20;59(4):AMD160-AMD181. doi: 10.1167/iovs.18-24882. Review.

PMID:
30357336
5.

SPECKLED HYPOAUTOFLUORESCENCE AS A SIGN OF RESOLVED SUBRETINAL HEMORRHAGE IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION.

Hussnain SA, Dolz-Marco R, Dunaief JL, Curcio CA, Freund KB.

Retina. 2018 Oct 22. doi: 10.1097/IAE.0000000000002367. [Epub ahead of print]

PMID:
30355956
6.

Viewing Retinal Vasculature in Alzheimer Disease.

Curcio CA.

JAMA Ophthalmol. 2018 Nov 1;136(11):1249-1250. doi: 10.1001/jamaophthalmol.2018.3569. No abstract available.

PMID:
30352117
7.

The clinical relevance of visualising the peripheral retina.

Quinn N, Csincsik L, Flynn E, Curcio CA, Kiss S, Sadda SR, Hogg R, Peto T, Lengyel I.

Prog Retin Eye Res. 2018 Oct 10. pii: S1350-9462(18)30039-9. doi: 10.1016/j.preteyeres.2018.10.001. [Epub ahead of print] Review.

8.

A New Online Portal Will Match Eye Banks With Researchers Seeking Human Ocular Tissues.

Curcio CA.

Invest Ophthalmol Vis Sci. 2018 Oct 1;59(12):4796-4797. doi: 10.1167/iovs.18-25632. No abstract available.

9.

PRESUMED FOVEAL BACILLARY LAYER DETACHMENT IN A PATIENT WITH TOXOPLASMOSIS CHORIORETINITIS AND PACHYCHOROID DISEASE.

Mehta N, Chong J, Tsui E, Duncan JL, Curcio CA, Freund KB, Modi Y.

Retin Cases Brief Rep. 2018 Aug 23. doi: 10.1097/ICB.0000000000000817. [Epub ahead of print]

PMID:
30142112
10.

The Border of Macular Atrophy in Age-Related Macular Degeneration: A Clinicopathologic Correlation.

Dolz-Marco R, Balaratnasingam C, Messinger JD, Li M, Ferrara D, Freund KB, Curcio CA.

Am J Ophthalmol. 2018 Sep;193:166-177. doi: 10.1016/j.ajo.2018.06.020. Epub 2018 Jul 5.

PMID:
29981740
11.

Re: Cuenca et al.: Cellular characterization of OCT and outer retinal bands using specific immunohistochemistry markers and clinical implications (Ophthalmology. 2018;125;407-422).

Curcio CA, Sparrow JR, Bonilha VL, Pollreisz A, Lujan BJ.

Ophthalmology. 2018 Jul;125(7):e47-e48. doi: 10.1016/j.ophtha.2018.02.031. No abstract available.

PMID:
29935676
12.

Subretinal drusenoid deposits AKA pseudodrusen.

Spaide RF, Ooto S, Curcio CA.

Surv Ophthalmol. 2018 Nov - Dec;63(6):782-815. doi: 10.1016/j.survophthal.2018.05.005. Epub 2018 May 31. Review.

PMID:
29859199
13.

HISTOLOGY OF GEOGRAPHIC ATROPHY SECONDARY TO AGE-RELATED MACULAR DEGENERATION: A Multilayer Approach.

Li M, Huisingh C, Messinger J, Dolz-Marco R, Ferrara D, Freund KB, Curcio CA.

Retina. 2018 Oct;38(10):1937-1953. doi: 10.1097/IAE.0000000000002182.

14.

Rod-Mediated Dark Adaptation and Macular Pigment Optical Density in Older Adults with Normal Maculas.

Zarubina AV, Huisingh CE, Clark ME, Sloan KR, McGwin G Jr, Crosson JN, Curcio CA, Owsley C.

Curr Eye Res. 2018 Jul;43(7):913-920. doi: 10.1080/02713683.2018.1460380. Epub 2018 May 1.

PMID:
29634370
15.

Choroidal and Sub-Retinal Pigment Epithelium Caverns: Multimodal Imaging and Correspondence with Friedman Lipid Globules.

Dolz-Marco R, Glover JP, Gal-Or O, Litts KM, Messinger JD, Zhang Y, Cozzi M, Pellegrini M, Freund KB, Staurenghi G, Curcio CA.

Ophthalmology. 2018 Aug;125(8):1287-1301. doi: 10.1016/j.ophtha.2018.02.036. Epub 2018 Apr 4.

PMID:
29625839
16.

Author Response: The Evolution of the Plateau, an Optical Coherence Tomography Signature Seen in Geographic Atrophy.

Tan ACS, Dansingani KK, Curcio CA, Freund KB.

Invest Ophthalmol Vis Sci. 2017 Dec 1;58(14):6196. doi: 10.1167/iovs.17-23339. No abstract available.

17.

OPTICAL COHERENCE TOMOGRAPHY AND HISTOLOGY OF AGE-RELATED MACULAR DEGENERATION SUPPORT MITOCHONDRIA AS REFLECTIVITY SOURCES.

Litts KM, Zhang Y, Freund KB, Curcio CA.

Retina. 2018 Mar;38(3):445-461. doi: 10.1097/IAE.0000000000001946. Review.

PMID:
29210936
18.

Tractional Abnormalities of the Central Foveal Bouquet in Epiretinal Membranes: Clinical Spectrum and Pathophysiological Perspectives.

Govetto A, Bhavsar KV, Virgili G, Gerber MJ, Freund KB, Curcio CA, Burgoyne CF, Hubschman JP, Sarraf D.

Am J Ophthalmol. 2017 Dec;184:167-180. doi: 10.1016/j.ajo.2017.10.011. Epub 2017 Oct 26.

PMID:
29106913
19.

Consensus Definition for Atrophy Associated with Age-Related Macular Degeneration on OCT: Classification of Atrophy Report 3.

Sadda SR, Guymer R, Holz FG, Schmitz-Valckenberg S, Curcio CA, Bird AC, Blodi BA, Bottoni F, Chakravarthy U, Chew EY, Csaky K, Danis RP, Fleckenstein M, Freund KB, Grunwald J, Hoyng CB, Jaffe GJ, Liakopoulos S, Monés JM, Pauleikhoff D, Rosenfeld PJ, Sarraf D, Spaide RF, Tadayoni R, Tufail A, Wolf S, Staurenghi G.

Ophthalmology. 2018 Apr;125(4):537-548. doi: 10.1016/j.ophtha.2017.09.028. Epub 2017 Nov 2.

PMID:
29103793
20.

Visualizing melanosomes, lipofuscin, and melanolipofuscin in human retinal pigment epithelium using serial block face scanning electron microscopy.

Pollreisz A, Messinger JD, Sloan KR, Mittermueller TJ, Weinhandl AS, Benson EK, Kidd GJ, Schmidt-Erfurth U, Curcio CA.

Exp Eye Res. 2018 Jan;166:131-139. doi: 10.1016/j.exer.2017.10.018. Epub 2017 Oct 21.

PMID:
29066281
21.

ApoA-I Mimetic Peptide 4F Reduces Age-Related Lipid Deposition in Murine Bruch's Membrane and Causes Its Structural Remodeling.

Rudolf M, Mir Mohi Sefat A, Miura Y, Tura A, Raasch W, Ranjbar M, Grisanti S, Aherrahrou Z, Wagner A, Messinger JD, Garber DW, Anantharamaiah GM, Curcio CA.

Curr Eye Res. 2018 Jan;43(1):135-146. doi: 10.1080/02713683.2017.1370118. Epub 2017 Oct 3.

PMID:
28972410
22.

Cuticular Drusen: Clinical Phenotypes and Natural History Defined Using Multimodal Imaging.

Balaratnasingam C, Cherepanoff S, Dolz-Marco R, Killingsworth M, Chen FK, Mendis R, Mrejen S, Too LK, Gal-Or O, Curcio CA, Freund KB, Yannuzzi LA.

Ophthalmology. 2018 Jan;125(1):100-118. doi: 10.1016/j.ophtha.2017.08.033. Epub 2017 Sep 28.

PMID:
28964580
23.

Clinicopathologic Correlation of Anti-Vascular Endothelial Growth Factor-Treated Type 3 Neovascularization in Age-Related Macular Degeneration.

Li M, Dolz-Marco R, Messinger JD, Wang L, Feist RM, Girkin CA, Gattoussi S, Ferrara D, Curcio CA, Freund KB.

Ophthalmology. 2018 Feb;125(2):276-287. doi: 10.1016/j.ophtha.2017.08.019. Epub 2017 Sep 28.

PMID:
28964579
24.

RNA expression in human retina.

Li M, Zauhar RJ, Grazal C, Curcio CA, DeAngelis MM, Stambolian D.

Hum Mol Genet. 2017 Aug 1;26(R1):R68-R74. doi: 10.1093/hmg/ddx219. Review.

25.

Activated Retinal Pigment Epithelium, an Optical Coherence Tomography Biomarker for Progression in Age-Related Macular Degeneration.

Curcio CA, Zanzottera EC, Ach T, Balaratnasingam C, Freund KB.

Invest Ophthalmol Vis Sci. 2017 May 1;58(6):BIO211-BIO226. doi: 10.1167/iovs.17-21872.

26.

Probing the Role of Inflammation in Age-Related Macular Degeneration.

Curcio CA, Huisingh C.

JAMA Ophthalmol. 2017 Aug 1;135(8):843-844. doi: 10.1001/jamaophthalmol.2017.2008. No abstract available.

PMID:
28654970
27.

ASSOCIATION BETWEEN VISUAL FUNCTION AND SUBRETINAL DRUSENOID DEPOSITS IN NORMAL AND EARLY AGE-RELATED MACULAR DEGENERATION EYES.

Neely D, Zarubina AV, Clark ME, Huisingh CE, Jackson GR, Zhang Y, McGwin G Jr, Curcio CA, Owsley C.

Retina. 2017 Jul;37(7):1329-1336. doi: 10.1097/IAE.0000000000001454.

28.

The Evolution of Outer Retinal Tubulation, a Neurodegeneration and Gliosis Prominent in Macular Diseases.

Dolz-Marco R, Litts KM, Tan ACS, Freund KB, Curcio CA.

Ophthalmology. 2017 Sep;124(9):1353-1367. doi: 10.1016/j.ophtha.2017.03.043. Epub 2017 Apr 26.

PMID:
28456420
29.

The Evolution of the Plateau, an Optical Coherence Tomography Signature Seen in Geographic Atrophy.

Tan ACS, Astroz P, Dansingani KK, Slakter JS, Yannuzzi LA, Curcio CA, Freund KB.

Invest Ophthalmol Vis Sci. 2017 Apr 1;58(4):2349-2358. doi: 10.1167/iovs.16-21237.

30.

DYNAMISM OF DOT SUBRETINAL DRUSENOID DEPOSITS IN AGE-RELATED MACULAR DEGENERATION DEMONSTRATED WITH ADAPTIVE OPTICS IMAGING.

Zhang Y, Wang X, Godara P, Zhang T, Clark ME, Witherspoon CD, Spaide RF, Owsley C, Curcio CA.

Retina. 2018 Jan;38(1):29-38. doi: 10.1097/IAE.0000000000001504.

PMID:
28196054
31.

Histologic and Optical Coherence Tomographic Correlates in Drusenoid Pigment Epithelium Detachment in Age-Related Macular Degeneration.

Balaratnasingam C, Messinger JD, Sloan KR, Yannuzzi LA, Freund KB, Curcio CA.

Ophthalmology. 2017 May;124(5):644-656. doi: 10.1016/j.ophtha.2016.12.034. Epub 2017 Jan 30.

32.

Subretinal Pigment Epithelial Deposition of Drusen Components Including Hydroxyapatite in a Primary Cell Culture Model.

Pilgrim MG, Lengyel I, Lanzirotti A, Newville M, Fearn S, Emri E, Knowles JC, Messinger JD, Read RW, Guidry C, Curcio CA.

Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):708-719. doi: 10.1167/iovs.16-21060.

33.

Reply.

Zarubina AV, Neely DC, Clark ME, Huisingh CE, Samuels BC, Zhang Y, McGwin G Jr, Owsley C, Curcio CA.

Ophthalmology. 2017 Feb;124(2):e20-e21. doi: 10.1016/j.ophtha.2016.05.013. No abstract available.

34.

Imaging Protocols in Clinical Studies in Advanced Age-Related Macular Degeneration: Recommendations from Classification of Atrophy Consensus Meetings.

Holz FG, Sadda SR, Staurenghi G, Lindner M, Bird AC, Blodi BA, Bottoni F, Chakravarthy U, Chew EY, Csaky K, Curcio CA, Danis R, Fleckenstein M, Freund KB, Grunwald J, Guymer R, Hoyng CB, Jaffe GJ, Liakopoulos S, Monés JM, Oishi A, Pauleikhoff D, Rosenfeld PJ, Sarraf D, Spaide RF, Tadayoni R, Tufail A, Wolf S, Schmitz-Valckenberg S; CAM group.

Ophthalmology. 2017 Apr;124(4):464-478. doi: 10.1016/j.ophtha.2016.12.002. Epub 2017 Jan 18.

PMID:
28109563
35.

Evaluation of Segmentation of the Superficial and Deep Vascular Layers of the Retina by Optical Coherence Tomography Angiography Instruments in Normal Eyes.

Spaide RF, Curcio CA.

JAMA Ophthalmol. 2017 Mar 1;135(3):259-262. doi: 10.1001/jamaophthalmol.2016.5327.

PMID:
28097291
36.

HYPERSPECTRAL AUTOFLUORESCENCE IMAGING OF DRUSEN AND RETINAL PIGMENT EPITHELIUM IN DONOR EYES WITH AGE-RELATED MACULAR DEGENERATION.

Tong Y, Ben Ami T, Hong S, Heintzmann R, Gerig G, Ablonczy Z, Curcio CA, Ach T, Smith RT.

Retina. 2016 Dec;36 Suppl 1:S127-S136. doi: 10.1097/IAE.0000000000001325.

37.

VISUALIZING RETINAL PIGMENT EPITHELIUM PHENOTYPES IN THE TRANSITION TO ATROPHY IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION.

Zanzottera EC, Ach T, Huisingh C, Messinger JD, Freund KB, Curcio CA.

Retina. 2016 Dec;36 Suppl 1:S26-S39. doi: 10.1097/IAE.0000000000001330.

38.

VISUALIZING RETINAL PIGMENT EPITHELIUM PHENOTYPES IN THE TRANSITION TO GEOGRAPHIC ATROPHY IN AGE-RELATED MACULAR DEGENERATION.

Zanzottera EC, Ach T, Huisingh C, Messinger JD, Spaide RF, Curcio CA.

Retina. 2016 Dec;36 Suppl 1:S12-S25. doi: 10.1097/IAE.0000000000001276.

39.

Retinal Pigment Epithelium Degeneration Associated With Subretinal Drusenoid Deposits in Age-Related Macular Degeneration.

Xu X, Liu X, Wang X, Clark ME, McGwin G Jr, Owsley C, Curcio CA, Zhang Y.

Am J Ophthalmol. 2017 Mar;175:87-98. doi: 10.1016/j.ajo.2016.11.021. Epub 2016 Dec 14.

40.

Clinical and Histopathologic Ocular Findings in Disseminated Mycobacterium chimaera Infection after Cardiothoracic Surgery.

Zweifel SA, Mihic-Probst D, Curcio CA, Barthelmes D, Thielken A, Keller PM, Hasse B, Böni C.

Ophthalmology. 2017 Feb;124(2):178-188. doi: 10.1016/j.ophtha.2016.09.032. Epub 2016 Nov 18.

PMID:
27871762
41.

Associations Between Retinal Pigment Epithelium and Drusen Volume Changes During the Lifecycle of Large Drusenoid Pigment Epithelial Detachments.

Balaratnasingam C, Yannuzzi LA, Curcio CA, Morgan WH, Querques G, Capuano V, Souied E, Jung J, Freund KB.

Invest Ophthalmol Vis Sci. 2016 Oct 1;57(13):5479-5489. doi: 10.1167/iovs.16-19816.

42.

Clinical Characteristics, Choroidal Neovascularization, and Predictors of Visual Outcomes in Acquired Vitelliform Lesions.

Balaratnasingam C, Hoang QV, Inoue M, Curcio CA, Dolz-Marco R, Yannuzzi NA, Dhrami-Gavazi E, Yannuzzi LA, Freund KB.

Am J Ophthalmol. 2016 Dec;172:28-38. doi: 10.1016/j.ajo.2016.09.008. Epub 2016 Sep 14.

PMID:
27640006
43.

EXPLORING PHOTORECEPTOR REFLECTIVITY THROUGH MULTIMODAL IMAGING OF OUTER RETINAL TUBULATION IN ADVANCED AGE-RELATED MACULAR DEGENERATION.

Litts KM, Wang X, Clark ME, Owsley C, Freund KB, Curcio CA, Zhang Y.

Retina. 2017 May;37(5):978-988. doi: 10.1097/IAE.0000000000001265.

44.

Spatial and Spectral Characterization of Human Retinal Pigment Epithelium Fluorophore Families by Ex Vivo Hyperspectral Autofluorescence Imaging.

Ben Ami T, Tong Y, Bhuiyan A, Huisingh C, Ablonczy Z, Ach T, Curcio CA, Smith RT.

Transl Vis Sci Technol. 2016 May 17;5(3):5. eCollection 2016 May.

45.

Sequence and Expression of Complement Factor H Gene Cluster Variants and Their Roles in Age-Related Macular Degeneration Risk.

Hughes AE, Bridgett S, Meng W, Li M, Curcio CA, Stambolian D, Bradley DT.

Invest Ophthalmol Vis Sci. 2016 May 1;57(6):2763-9. doi: 10.1167/iovs.15-18744.

46.

Quantitative Analysis of Outer Retinal Tubulation in Age-Related Macular Degeneration From Spectral-Domain Optical Coherence Tomography and Histology.

Litts KM, Ach T, Hammack KM, Sloan KR, Zhang Y, Freund KB, Curcio CA.

Invest Ophthalmol Vis Sci. 2016 May 1;57(6):2647-56. doi: 10.1167/iovs.16-19262.

47.

Coronary Artery Disease and Reticular Macular Disease, a Subphenotype of Early Age-Related Macular Degeneration.

Cymerman RM, Skolnick AH, Cole WJ, Nabati C, Curcio CA, Smith RT.

Curr Eye Res. 2016 Nov;41(11):1482-1488. Epub 2016 May 9.

48.

Visual Function in Older Eyes in Normal Macular Health: Association with Incident Early Age-Related Macular Degeneration 3 Years Later.

Owsley C, Clark ME, Huisingh CE, Curcio CA, McGwin G Jr.

Invest Ophthalmol Vis Sci. 2016 Apr;57(4):1782-9. doi: 10.1167/iovs.15-18962.

49.

Relating Retinal Morphology and Function in Aging and Early to Intermediate Age-related Macular Degeneration Subjects.

Sevilla MB, McGwin G Jr, Lad EM, Clark M, Yuan EL, Farsiu S, Curcio CA, Owsley C, Toth CA.

Am J Ophthalmol. 2016 May;165:65-77. doi: 10.1016/j.ajo.2016.02.021. Epub 2016 Mar 3.

50.

Multi-nucleate retinal pigment epithelium cells of the human macula exhibit a characteristic and highly specific distribution.

Starnes AC, Huisingh C, McGwin G Jr, Sloan KR, Ablonczy Z, Smith RT, Curcio CA, Ach T.

Vis Neurosci. 2016;33:e001. doi: 10.1017/S0952523815000310.

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