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Items: 37

1.

The P450 side chain cleavage enzyme Cyp11a2 facilitates steroidogenesis in zebrafish.

Li N, Oakes JA, Storbeck K, Cunliffe VT, Krone N.

J Endocrinol. 2019 Nov 1. pii: JOE-19-0384.R1. doi: 10.1530/JOE-19-0384. [Epub ahead of print]

PMID:
31693487
2.

Ferredoxin 1b Deficiency Leads to Testis Disorganization, Impaired Spermatogenesis, and Feminization in Zebrafish.

Oakes JA, Li N, Wistow BRC, Griffin A, Barnard L, Storbeck KH, Cunliffe VT, Krone NP.

Endocrinology. 2019 Oct 1;160(10):2401-2416. doi: 10.1210/en.2019-00068.

PMID:
31322700
3.

Increased EZH2 expression in prostate cancer is associated with metastatic recurrence following external beam radiotherapy.

Wu X, Scott H, Carlsson SV, Sjoberg DD, Cerundolo L, Lilja H, Prevo R, Rieunier G, Macaulay V, Higgins GS, Verrill CL, Lamb AD, Cunliffe VT, Bountra C, Hamdy FC, Bryant RJ.

Prostate. 2019 Jul;79(10):1079-1089. doi: 10.1002/pros.23817. Epub 2019 May 18.

4.

The effect of hyperglycemia on neurovascular coupling and cerebrovascular patterning in zebrafish.

Chhabria K, Plant K, Bandmann O, Wilkinson RN, Martin C, Kugler E, Armitage PA, Santoscoy PL, Cunliffe VT, Huisken J, McGown A, Ramesh T, Chico TJ, Howarth C.

J Cereb Blood Flow Metab. 2020 Feb;40(2):298-313. doi: 10.1177/0271678X18810615. Epub 2018 Nov 6.

5.

A Caenorhabditis elegans assay of seizure-like activity optimised for identifying antiepileptic drugs and their mechanisms of action.

Wong SQ, Jones A, Dodd S, Grimes D, Barclay JW, Marson AG, Cunliffe VT, Burgoyne RD, Sills GJ, Morgan A.

J Neurosci Methods. 2018 Nov 1;309:132-142. doi: 10.1016/j.jneumeth.2018.09.004. Epub 2018 Sep 3.

6.

Imaging Neuronal Activity in the Optic Tectum of Late Stage Larval Zebrafish.

Bergmann K, Meza Santoscoy P, Lygdas K, Nikolaeva Y, MacDonald RB, Cunliffe VT, Nikolaev A.

J Dev Biol. 2018 Mar 9;6(1). pii: E6. doi: 10.3390/jdb6010006.

7.

Epigenetics and primary care.

Lehane DB, Cunliffe VT, Mitchell C, Burton C.

Br J Gen Pract. 2018 Jan;68(666):8-9. doi: 10.3399/bjgp17X693977. No abstract available.

8.

Genetic Disruption of 21-Hydroxylase in Zebrafish Causes Interrenal Hyperplasia.

Eachus H, Zaucker A, Oakes JA, Griffin A, Weger M, Güran T, Taylor A, Harris A, Greenfield A, Quanson JL, Storbeck KH, Cunliffe VT, Müller F, Krone N.

Endocrinology. 2017 Dec 1;158(12):4165-4173. doi: 10.1210/en.2017-00549.

9.

Disrupted-in-Schizophrenia-1 is essential for normal hypothalamic-pituitary-interrenal (HPI) axis function.

Eachus H, Bright C, Cunliffe VT, Placzek M, Wood JD, Watt PJ.

Hum Mol Genet. 2017 Jun 1;26(11):1992-2005. doi: 10.1093/hmg/ddx076.

10.

Epigenetic memory in response to environmental stressors.

Vineis P, Chatziioannou A, Cunliffe VT, Flanagan JM, Hanson M, Kirsch-Volders M, Kyrtopoulos S.

FASEB J. 2017 Jun;31(6):2241-2251. doi: 10.1096/fj.201601059RR. Epub 2017 Mar 9.

11.

The epigenetic impacts of social stress: how does social adversity become biologically embedded?

Cunliffe VT.

Epigenomics. 2016 Dec;8(12):1653-1669. Epub 2016 Nov 21. Review.

12.

Hedgehog signalling acts upstream of Laminin alpha1 transcription in the zebrafish paraxial mesoderm.

Pickering J, Cunliffe VT, Van Eeden F, Borycki AG.

Matrix Biol. 2017 Oct;62:58-74. doi: 10.1016/j.matbio.2016.11.004. Epub 2016 Nov 14.

13.

Histone modifications in zebrafish development.

Cunliffe VT.

Methods Cell Biol. 2016;135:361-85. doi: 10.1016/bs.mcb.2016.05.005. Epub 2016 Jun 20.

PMID:
27443936
14.

Sonic hedgehog functions upstream of disrupted-in-schizophrenia 1 (disc1): implications for mental illness.

Boyd PJ, Cunliffe VT, Roy S, Wood JD.

Biol Open. 2015 Sep 24;4(10):1336-43. doi: 10.1242/bio.012005.

15.

Building a zebrafish toolkit for investigating the pathobiology of epilepsy and identifying new treatments for epileptic seizures.

Cunliffe VT.

J Neurosci Methods. 2016 Feb 15;260:91-5. doi: 10.1016/j.jneumeth.2015.07.015. Epub 2015 Jul 26. Review.

PMID:
26219659
16.

Experience-sensitive epigenetic mechanisms, developmental plasticity, and the biological embedding of chronic disease risk.

Cunliffe VT.

Wiley Interdiscip Rev Syst Biol Med. 2015 Mar-Apr;7(2):53-71. doi: 10.1002/wsbm.1291. Epub 2015 Feb 20. Review.

PMID:
25704729
17.

The role of Sox6 in zebrafish muscle fiber type specification.

Jackson HE, Ono Y, Wang X, Elworthy S, Cunliffe VT, Ingham PW.

Skelet Muscle. 2015 Jan 27;5(1):2. doi: 10.1186/s13395-014-0026-2. eCollection 2015.

18.

Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus.

Johnson MR, Behmoaras J, Bottolo L, Krishnan ML, Pernhorst K, Santoscoy PLM, Rossetti T, Speed D, Srivastava PK, Chadeau-Hyam M, Hajji N, Dabrowska A, Rotival M, Razzaghi B, Kovac S, Wanisch K, Grillo FW, Slaviero A, Langley SR, Shkura K, Roncon P, De T, Mattheisen M, Niehusmann P, O'Brien TJ, Petrovski S, von Lehe M, Hoffmann P, Eriksson J, Coffey AJ, Cichon S, Walker M, Simonato M, Danis B, Mazzuferi M, Foerch P, Schoch S, De Paola V, Kaminski RM, Cunliffe VT, Becker AJ, Petretto E.

Nat Commun. 2015 Jan 23;6:6031. doi: 10.1038/ncomms7031.

19.

Epilepsy research methods update: Understanding the causes of epileptic seizures and identifying new treatments using non-mammalian model organisms.

Cunliffe VT, Baines RA, Giachello CN, Lin WH, Morgan A, Reuber M, Russell C, Walker MC, Williams RS.

Seizure. 2015 Jan;24:44-51. doi: 10.1016/j.seizure.2014.09.018. Epub 2014 Oct 13. Review.

20.

Identification of compounds with anti-convulsant properties in a zebrafish model of epileptic seizures.

Baxendale S, Holdsworth CJ, Meza Santoscoy PL, Harrison MR, Fox J, Parkin CA, Ingham PW, Cunliffe VT.

Dis Model Mech. 2012 Nov;5(6):773-84. doi: 10.1242/dmm.010090. Epub 2012 Jun 21.

21.
22.

The epigenetic regulator Histone Deacetylase 1 promotes transcription of a core neurogenic programme in zebrafish embryos.

Harrison MR, Georgiou AS, Spaink HP, Cunliffe VT.

BMC Genomics. 2011 Jan 12;12:24. doi: 10.1186/1471-2164-12-24.

23.

Genetic and chemical modulation of spastin-dependent axon outgrowth in zebrafish embryos indicates a role for impaired microtubule dynamics in hereditary spastic paraplegia.

Butler R, Wood JD, Landers JA, Cunliffe VT.

Dis Model Mech. 2010 Nov-Dec;3(11-12):743-51. doi: 10.1242/dmm.004002. Epub 2010 Sep 9.

24.

Submillimeter-scale surface gradients of immobilized protein ligands.

Walker RA, Cunliffe VT, Whittle JD, Steele DA, Short RD.

Langmuir. 2009 Apr 21;25(8):4243-6. doi: 10.1021/la803775m.

PMID:
19301839
25.

Disrupted-in-schizophrenia 1 and neuregulin 1 are required for the specification of oligodendrocytes and neurones in the zebrafish brain.

Wood JD, Bonath F, Kumar S, Ross CA, Cunliffe VT.

Hum Mol Genet. 2009 Feb 1;18(3):391-404. doi: 10.1093/hmg/ddn361. Epub 2008 Nov 7.

PMID:
18996920
26.

Eloquent silence: developmental functions of Class I histone deacetylases.

Cunliffe VT.

Curr Opin Genet Dev. 2008 Oct;18(5):404-10. doi: 10.1016/j.gde.2008.10.001. Epub 2008 Oct 16. Review.

27.

A novel vertebrate model of Staphylococcus aureus infection reveals phagocyte-dependent resistance of zebrafish to non-host specialized pathogens.

Prajsnar TK, Cunliffe VT, Foster SJ, Renshaw SA.

Cell Microbiol. 2008 Nov;10(11):2312-25. doi: 10.1111/j.1462-5822.2008.01213.x. Epub 2008 Aug 18.

PMID:
18715285
28.

The Polycomb Group protein EZH2 regulates actin polymerization in human prostate cancer cells.

Bryant RJ, Winder SJ, Cross SS, Hamdy FC, Cunliffe VT.

Prostate. 2008 Feb 15;68(3):255-63.

PMID:
18095286
29.

EZH2 promotes proliferation and invasiveness of prostate cancer cells.

Bryant RJ, Cross NA, Eaton CL, Hamdy FC, Cunliffe VT.

Prostate. 2007 Apr 1;67(5):547-56.

PMID:
17252556
30.

The microtubule-severing protein Spastin is essential for axon outgrowth in the zebrafish embryo.

Wood JD, Landers JA, Bingley M, McDermott CJ, Thomas-McArthur V, Gleadall LJ, Shaw PJ, Cunliffe VT.

Hum Mol Genet. 2006 Sep 15;15(18):2763-71. Epub 2006 Aug 7.

PMID:
16893913
31.

Histone deacetylase 1 is essential for oligodendrocyte specification in the zebrafish CNS.

Cunliffe VT, Casaccia-Bonnefil P.

Mech Dev. 2006 Jan;123(1):24-30. Epub 2005 Dec 1.

32.

Foxn1 is required for tissue assembly and desmosomal cadherin expression in the hair shaft.

Johns SA, Soullier S, Rashbass P, Cunliffe VT.

Dev Dyn. 2005 Apr;232(4):1062-8.

34.
35.

Identification of putative interaction partners for the Xenopus Polycomb-group protein Xeed.

Showell C, Cunliffe VT.

Gene. 2002 May 29;291(1-2):95-104.

PMID:
12095683
36.

Complete rescue of the nude mutant phenotype by a wild-type Foxn1 transgene.

Cunliffe VT, Furley AJ, Keenan D.

Mamm Genome. 2002 May;13(5):245-52.

PMID:
12016512
37.

Switching on the notochord.

Cunliffe VT, Ingham PW.

Genes Dev. 1999 Jul 1;13(13):1643-6. No abstract available.

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