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Items: 28


LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance.

Cunha LD, Yang M, Carter R, Guy C, Harris L, Crawford JC, Quarato G, Boada-Romero E, Kalkavan H, Johnson MDL, Natarajan S, Turnis ME, Finkelstein D, Opferman JT, Gawad C, Green DR.

Cell. 2018 Oct 4;175(2):429-441.e16. doi: 10.1016/j.cell.2018.08.061. Epub 2018 Sep 20.


Effect of a single-tufted toothbrush on the control of dental biofilm in orthodontic patients: A randomized clinical trial.

Cunha LDD, Peruzzo DC, Costa LA, Pereira ALP, Benatti BB.

Int J Dent Hyg. 2018 Nov;16(4):512-518. doi: 10.1111/idh.12360. Epub 2018 Aug 20.


Theoretical and experimental study for the biomimetic recognition of levothyroxine hormone on magnetic molecularly imprinted polymer.

Moura SL, Fajardo LM, Cunha LDA, Sotomayor MDPT, Machado FBC, Ferrão LFA, Pividori MI.

Biosens Bioelectron. 2018 Jun 1;107:203-210. doi: 10.1016/j.bios.2018.01.028. Epub 2018 Jan 31.


LC3-Associated Phagocytosis and Inflammation.

Heckmann BL, Boada-Romero E, Cunha LD, Magne J, Green DR.

J Mol Biol. 2017 Nov 24;429(23):3561-3576. doi: 10.1016/j.jmb.2017.08.012. Epub 2017 Aug 25. Review.


Inhibition of caspase-1 or gasdermin-D enable caspase-8 activation in the Naip5/NLRC4/ASC inflammasome.

Mascarenhas DPA, Cerqueira DM, Pereira MSF, Castanheira FVS, Fernandes TD, Manin GZ, Cunha LD, Zamboni DS.

PLoS Pathog. 2017 Aug 3;13(8):e1006502. doi: 10.1371/journal.ppat.1006502. eCollection 2017 Aug.


AIM2 Engages Active but Unprocessed Caspase-1 to Induce Noncanonical Activation of the NLRP3 Inflammasome.

Cunha LD, Silva ALN, Ribeiro JM, Mascarenhas DPA, Quirino GFS, Santos LL, Flavell RA, Zamboni DS.

Cell Rep. 2017 Jul 25;20(4):794-805. doi: 10.1016/j.celrep.2017.06.086.


Corrigendum: Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells.

Martinez J, Cunha LD, Park S, Yang M, Lu Q, Orchard R, Li QZ, Yan M, Janke L, Guy C, Linkermann A, Virgin HW, Green DR.

Nature. 2016 Nov 3;539(7627):124. doi: 10.1038/nature19837. Epub 2016 Sep 28. No abstract available.


Murine Alveolar Macrophages Are Highly Susceptible to Replication of Coxiella burnetii Phase II In Vitro.

Fernandes TD, Cunha LD, Ribeiro JM, Massis LM, Lima-Junior DS, Newton HJ, Zamboni DS.

Infect Immun. 2016 Aug 19;84(9):2439-48. doi: 10.1128/IAI.00411-16. Print 2016 Sep.


Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease.

Chu H, Khosravi A, Kusumawardhani IP, Kwon AH, Vasconcelos AC, Cunha LD, Mayer AE, Shen Y, Wu WL, Kambal A, Targan SR, Xavier RJ, Ernst PB, Green DR, McGovern DP, Virgin HW, Mazmanian SK.

Science. 2016 May 27;352(6289):1116-20. doi: 10.1126/science.aad9948. Epub 2016 May 5.


Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells.

Martinez J, Cunha LD, Park S, Yang M, Lu Q, Orchard R, Li QZ, Yan M, Janke L, Guy C, Linkermann A, Virgin HW, Green DR.

Nature. 2016 May 5;533(7601):115-9. doi: 10.1038/nature17950. Epub 2016 Apr 20. Erratum in: Nature. 2016 Nov 3;539(7627):124.


Inhibition of inflammasome activation by Coxiella burnetii type IV secretion system effector IcaA.

Cunha LD, Ribeiro JM, Fernandes TD, Massis LM, Khoo CA, Moffatt JH, Newton HJ, Roy CR, Zamboni DS.

Nat Commun. 2015 Dec 21;6:10205. doi: 10.1038/ncomms10205.


Relationship between periodontal status and degree of visual impairment in institutionalized individuals.

da Cunha LD, Melo Proença MA, Rodrigues VP, Vasconcelos Pereira AF, Benatti BB.

Eur J Dent. 2015 Jul-Sep;9(3):324-8. doi: 10.4103/1305-7456.163322.


Caspase-1 but Not Caspase-11 Is Required for NLRC4-Mediated Pyroptosis and Restriction of Infection by Flagellated Legionella Species in Mouse Macrophages and In Vivo.

Cerqueira DM, Pereira MS, Silva AL, Cunha LD, Zamboni DS.

J Immunol. 2015 Sep 1;195(5):2303-11. doi: 10.4049/jimmunol.1501223. Epub 2015 Jul 31.


Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins.

Martinez J, Malireddi RK, Lu Q, Cunha LD, Pelletier S, Gingras S, Orchard R, Guan JL, Tan H, Peng J, Kanneganti TD, Virgin HW, Green DR.

Nat Cell Biol. 2015 Jul;17(7):893-906. doi: 10.1038/ncb3192. Epub 2015 Jun 22.


Recognition of Legionella pneumophila nucleic acids by innate immune receptors.

Cunha LD, Zamboni DS.

Microbes Infect. 2014 Dec;16(12):985-90. doi: 10.1016/j.micinf.2014.08.008. Epub 2014 Aug 27. Review.


MyD88-, but not Nod1- and/or Nod2-deficient mice, show increased susceptibility to polymicrobial sepsis due to impaired local inflammatory response.

Sônego F, Castanheira FV, Czaikoski PG, Kanashiro A, Souto FO, França RO, Nascimento DC, Freitas A, Spiller F, Cunha LD, Zamboni DS, Alves-Filho JC, Cunha FQ.

PLoS One. 2014 Aug 1;9(8):e103734. doi: 10.1371/journal.pone.0103734. eCollection 2014.


The use of a heterogeneously controlled mouse population reveals a significant correlation of acute phase parasitemia with mortality in Chagas disease.

Sanches TL, Cunha LD, Silva GK, Guedes PM, Silva JS, Zamboni DS.

PLoS One. 2014 Mar 20;9(3):e91640. doi: 10.1371/journal.pone.0091640. eCollection 2014.


Subversion of inflammasome activation and pyroptosis by pathogenic bacteria.

Cunha LD, Zamboni DS.

Front Cell Infect Microbiol. 2013 Nov 26;3:76. doi: 10.3389/fcimb.2013.00076. eCollection 2013. Review.


Inflammasome-derived IL-1β production induces nitric oxide-mediated resistance to Leishmania.

Lima-Junior DS, Costa DL, Carregaro V, Cunha LD, Silva AL, Mineo TW, Gutierrez FR, Bellio M, Bortoluci KR, Flavell RA, Bozza MT, Silva JS, Zamboni DS.

Nat Med. 2013 Jul;19(7):909-15. doi: 10.1038/nm.3221. Epub 2013 Jun 9.


Critical role of ASC inflammasomes and bacterial type IV secretion system in caspase-1 activation and host innate resistance to Brucella abortus infection.

Gomes MT, Campos PC, Oliveira FS, Corsetti PP, Bortoluci KR, Cunha LD, Zamboni DS, Oliveira SC.

J Immunol. 2013 Apr 1;190(7):3629-38. doi: 10.4049/jimmunol.1202817. Epub 2013 Mar 4.


A parent-of-origin effect determines the susceptibility of a non-informative F1 population to Trypanosoma cruzi infection in vivo.

Silva GK, Cunha LD, Horta CV, Silva AL, Gutierrez FR, Silva JS, Zamboni DS.

PLoS One. 2013;8(2):e56347. doi: 10.1371/journal.pone.0056347. Epub 2013 Feb 11.


NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B(4) in a murine model of gout.

Amaral FA, Costa VV, Tavares LD, Sachs D, Coelho FM, Fagundes CT, Soriani FM, Silveira TN, Cunha LD, Zamboni DS, Quesniaux V, Peres RS, Cunha TM, Cunha FQ, Ryffel B, Souza DG, Teixeira MM.

Arthritis Rheum. 2012 Feb;64(2):474-84. doi: 10.1002/art.33355.


Influence of ridge inclination and implant localization on the association of mandibular Kennedy class I removable partial denture.

Cunha LD, Pellizzer EP, Verri FR, Falcón-Antenucci RM, Goiato MC.

J Craniofac Surg. 2011 May;22(3):871-5. doi: 10.1097/SCS.0b013e31820f7d6a.


A novel pathway for inducible nitric-oxide synthase activation through inflammasomes.

Buzzo CL, Campopiano JC, Massis LM, Lage SL, Cassado AA, Leme-Souza R, Cunha LD, Russo M, Zamboni DS, Amarante-Mendes GP, Bortoluci KR.

J Biol Chem. 2010 Oct 15;285(42):32087-95. doi: 10.1074/jbc.M110.124297. Epub 2010 Aug 11.


Cutting edge: nucleotide-binding oligomerization domain 1-dependent responses account for murine resistance against Trypanosoma cruzi infection.

Silva GK, Gutierrez FR, Guedes PM, Horta CV, Cunha LD, Mineo TW, Santiago-Silva J, Kobayashi KS, Flavell RA, Silva JS, Zamboni DS.

J Immunol. 2010 Feb 1;184(3):1148-52. doi: 10.4049/jimmunol.0902254. Epub 2009 Dec 30.


Interaction between estradiol and follicle-stimulating hormone promotes in vitro survival and development of caprine preantral follicles.

Lima-Verde IB, Matos MH, Saraiva MV, Bruno JB, Tenório SB, Martins FS, Rossetto R, Cunha LD, Name KP, Báo SN, Campello CC, Figueiredo JR.

Cells Tissues Organs. 2010;191(3):240-7. doi: 10.1159/000231484. Epub 2009 Jul 28.


Evaluation of the influence of location of osseointegrated implants associated with mandibular removable partial dentures.

Cunha LD, Pellizzer EP, Verri FR, Pereira JA.

Implant Dent. 2008 Sep;17(3):278-87. doi: 10.1097/ID.0b013e31818363b2.


Ultrastructural description and cytochemical study of the spermatozoon of Crotallus durissus (Squamata, Serpentes).

Cunha LD, Tavares-Bastos L, Báo SN.

Micron. 2008 Oct;39(7):915-25. doi: 10.1016/j.micron.2007.11.012. Epub 2007 Dec 7.


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