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Items: 39

1.

Neutron and X-ray analysis of the Fenna-Matthews-Olson photosynthetic antenna complex from Prosthecochloris aestuarii.

Lu X, Selvaraj B, Ghimire-Rijal S, Orf GS, Meilleur F, Blankenship RE, Cuneo MJ, Myles DAA.

Acta Crystallogr F Struct Biol Commun. 2019 Mar 1;75(Pt 3):171-175. doi: 10.1107/S2053230X19000724. Epub 2019 Feb 20.

PMID:
30839291
2.

Encoding of Promiscuity in an Aminoglycoside Acetyltransferase.

Kumar P, Selvaraj B, Serpersu EH, Cuneo MJ.

J Med Chem. 2018 Nov 21;61(22):10218-10227. doi: 10.1021/acs.jmedchem.8b01393. Epub 2018 Oct 31.

PMID:
30347146
3.

Differential Substrate Recognition by Maltose Binding Proteins Influenced by Structure and Dynamics.

Shukla S, Bafna K, Gullett C, Myles DAA, Agarwal PK, Cuneo MJ.

Biochemistry. 2018 Oct 9;57(40):5864-5876. doi: 10.1021/acs.biochem.8b00783. Epub 2018 Sep 25.

PMID:
30204415
4.

Modulating Enzyme Activity by Altering Protein Dynamics with Solvent.

Duff MR Jr, Borreguero JM, Cuneo MJ, Ramanathan A, He J, Kamath G, Chennubhotla SC, Meilleur F, Howell EE, Herwig KW, Myles DAA, Agarwal PK.

Biochemistry. 2018 Jul 24;57(29):4263-4275. doi: 10.1021/acs.biochem.8b00424. Epub 2018 Jul 6.

PMID:
29901984
5.

A low-barrier hydrogen bond mediates antibiotic resistance in a noncanonical catalytic triad.

Kumar P, Serpersu EH, Cuneo MJ.

Sci Adv. 2018 Apr 4;4(4):eaas8667. doi: 10.1126/sciadv.aas8667. eCollection 2018 Apr.

6.

"To Be or Not to Be" Protonated: Atomic Details of Human Carbonic Anhydrase-Clinical Drug Complexes by Neutron Crystallography and Simulation.

Kovalevsky A, Aggarwal M, Velazquez H, Cuneo MJ, Blakeley MP, Weiss KL, Smith JC, Fisher SZ, McKenna R.

Structure. 2018 Mar 6;26(3):383-390.e3. doi: 10.1016/j.str.2018.01.006. Epub 2018 Feb 8.

7.

Protein extraction into the bicontinuous microemulsion phase of a Water/SDS/pentanol/dodecane winsor-III system: Effect on nanostructure and protein conformation.

Hayes DG, Ye R, Dunlap RN, Cuneo MJ, Pingali SV, O'Neill HM, Urban VS.

Colloids Surf B Biointerfaces. 2017 Dec 1;160:144-153. doi: 10.1016/j.colsurfb.2017.09.005. Epub 2017 Sep 7.

PMID:
28922633
8.

Unencumbered Pol β lyase activity in nucleosome core particles.

Rodriguez Y, Howard MJ, Cuneo MJ, Prasad R, Wilson SH.

Nucleic Acids Res. 2017 Sep 6;45(15):8901-8915. doi: 10.1093/nar/gkx593.

9.

Periplasmic Binding Protein Dimer Has a Second Allosteric Event Tied to Ligand Binding.

Li L, Ghimire-Rijal S, Lucas SL, Stanley CB, Wright E, Agarwal PK, Myles DA, Cuneo MJ.

Biochemistry. 2017 Oct 10;56(40):5328-5337. doi: 10.1021/acs.biochem.7b00657. Epub 2017 Sep 22.

PMID:
28876049
10.

Neutron crystallographic studies of T4 lysozyme at cryogenic temperature.

Li L, Shukla S, Meilleur F, Standaert RF, Pierce J, Myles DAA, Cuneo MJ.

Protein Sci. 2017 Oct;26(10):2098-2104. doi: 10.1002/pro.3231. Epub 2017 Sep 6.

11.

Neutron and Atomic Resolution X-ray Structures of a Lytic Polysaccharide Monooxygenase Reveal Copper-Mediated Dioxygen Binding and Evidence for N-Terminal Deprotonation.

Bacik JP, Mekasha S, Forsberg Z, Kovalevsky AY, Vaaje-Kolstad G, Eijsink VGH, Nix JC, Coates L, Cuneo MJ, Unkefer CJ, Chen JC.

Biochemistry. 2017 May 23;56(20):2529-2532. doi: 10.1021/acs.biochem.7b00019. Epub 2017 May 11.

PMID:
28481095
12.

Perturbation of bacteriochlorophyll molecules in Fenna-Matthews-Olson protein complexes through mutagenesis of cysteine residues.

Saer R, Orf GS, Lu X, Zhang H, Cuneo MJ, Myles DAA, Blankenship RE.

Biochim Biophys Acta. 2016 Sep;1857(9):1455-1463. doi: 10.1016/j.bbabio.2016.04.007. Epub 2016 Apr 22.

13.

Structural characterization of the virulence factor Sda1 nuclease from Streptococcus pyogenes.

Moon AF, Krahn JM, Lu X, Cuneo MJ, Pedersen LC.

Nucleic Acids Res. 2016 May 5;44(8):3946-57. doi: 10.1093/nar/gkw143. Epub 2016 Mar 11.

14.

Neutron and high-resolution room-temperature X-ray data collection from crystallized lytic polysaccharide monooxygenase.

Bacik JP, Mekasha S, Forsberg Z, Kovalevsky A, Nix JC, Cuneo MJ, Coates L, Vaaje-Kolstad G, Chen JC, Eijsink VG, Unkefer CJ.

Acta Crystallogr F Struct Biol Commun. 2015 Nov;71(Pt 11):1448-52. doi: 10.1107/S2053230X15019743. Epub 2015 Oct 30.

15.

Capturing snapshots of APE1 processing DNA damage.

Freudenthal BD, Beard WA, Cuneo MJ, Dyrkheeva NS, Wilson SH.

Nat Struct Mol Biol. 2015 Nov;22(11):924-31. doi: 10.1038/nsmb.3105. Epub 2015 Oct 12.

16.

Oligomerization state and pigment binding strength of the peridinin-Chl a-protein.

Jiang J, Zhang H, Lu X, Lu Y, Cuneo MJ, O'Neill HM, Urban V, Lo CS, Blankenship RE.

FEBS Lett. 2015 Sep 14;589(19 Pt B):2713-9. doi: 10.1016/j.febslet.2015.07.039. Epub 2015 Aug 1.

17.

Characterization of the redox transition of the XRCC1 N-terminal domain.

Gabel SA, Smith CE, Cuneo MJ, Mueller GA, Kirby TW, DeRose EF, Krahn JM, London RE.

Structure. 2014 Dec 2;22(12):1754-1763. doi: 10.1016/j.str.2014.09.012. Epub 2014 Nov 13.

18.

Duplication of genes in an ATP-binding cassette transport system increases dynamic range while maintaining ligand specificity.

Ghimire-Rijal S, Lu X, Myles DA, Cuneo MJ.

J Biol Chem. 2014 Oct 24;289(43):30090-100. doi: 10.1074/jbc.M114.590992. Epub 2014 Sep 10.

19.

Crystallization and preliminary X-ray diffraction analysis of Hypocrea jecorina Cel7A in two new crystal forms.

Bodenheimer AM, Cuneo MJ, Swartz PD, He J, O'Neill HM, Myles DA, Evans BR, Meilleur F.

Acta Crystallogr F Struct Biol Commun. 2014 Jun;70(Pt 6):773-6. doi: 10.1107/S2053230X14008851. Epub 2014 May 10.

20.

Selective unfolding of one Ribonuclease H domain of HIV reverse transcriptase is linked to homodimer formation.

Zheng X, Pedersen LC, Gabel SA, Mueller GA, Cuneo MJ, DeRose EF, Krahn JM, London RE.

Nucleic Acids Res. 2014 Apr;42(8):5361-77. doi: 10.1093/nar/gku143. Epub 2014 Feb 25.

21.

Molecular details of ligand selectivity determinants in a promiscuous β-glucan periplasmic binding protein.

Munshi P, Stanley CB, Ghimire-Rijal S, Lu X, Myles DA, Cuneo MJ.

BMC Struct Biol. 2013 Oct 4;13:18. doi: 10.1186/1472-6807-13-18.

22.

Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses.

Horton JK, Stefanick DF, Gassman NR, Williams JG, Gabel SA, Cuneo MJ, Prasad R, Kedar PS, Derose EF, Hou EW, London RE, Wilson SH.

DNA Repair (Amst). 2013 Sep;12(9):774-85. doi: 10.1016/j.dnarep.2013.06.004. Epub 2013 Jul 18.

23.

Structural studies of the PARP-1 BRCT domain.

Loeffler PA, Cuneo MJ, Mueller GA, DeRose EF, Gabel SA, London RE.

BMC Struct Biol. 2011 Oct 3;11:37. doi: 10.1186/1472-6807-11-37.

24.

The structural basis for partitioning of the XRCC1/DNA ligase III-α BRCT-mediated dimer complexes.

Cuneo MJ, Gabel SA, Krahn JM, Ricker MA, London RE.

Nucleic Acids Res. 2011 Sep 1;39(17):7816-27. doi: 10.1093/nar/gkr419. Epub 2011 Jun 7.

25.

Programmable ligand detection system in plants through a synthetic signal transduction pathway.

Antunes MS, Morey KJ, Smith JJ, Albrecht KD, Bowen TA, Zdunek JK, Troupe JF, Cuneo MJ, Webb CT, Hellinga HW, Medford JI.

PLoS One. 2011 Jan 25;6(1):e16292. doi: 10.1371/journal.pone.0016292.

26.

Mutational and biochemical analysis of the DNA-entry nuclease EndA from Streptococcus pneumoniae.

Midon M, Schäfer P, Pingoud A, Ghosh M, Moon AF, Cuneo MJ, London RE, Meiss G.

Nucleic Acids Res. 2011 Jan;39(2):623-34. doi: 10.1093/nar/gkq802. Epub 2010 Sep 15.

27.

Der p 5 crystal structure provides insight into the group 5 dust mite allergens.

Mueller GA, Gosavi RA, Krahn JM, Edwards LL, Cuneo MJ, Glesner J, Pomés A, Chapman MD, London RE, Pedersen LC.

J Biol Chem. 2010 Aug 13;285(33):25394-401. doi: 10.1074/jbc.M110.128306. Epub 2010 Jun 9.

28.

Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity.

Cuneo MJ, London RE.

Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6805-10. doi: 10.1073/pnas.0914077107. Epub 2010 Mar 29.

29.

Homodimerization of the p51 subunit of HIV-1 reverse transcriptase.

Zheng X, Mueller GA, Cuneo MJ, Derose EF, London RE.

Biochemistry. 2010 Apr 6;49(13):2821-33. doi: 10.1021/bi902116z.

30.

Identification and functional characterization of a novel acetylcholine-binding protein from the marine annelid Capitella teleta.

McCormack T, Petrovich RM, Mercier KA, DeRose EF, Cuneo MJ, Williams J, Johnson KL, Lamb PW, London RE, Yakel JL.

Biochemistry. 2010 Mar 16;49(10):2279-87. doi: 10.1021/bi902023y.

32.

Structural adaptations that modulate monosaccharide, disaccharide, and trisaccharide specificities in periplasmic maltose-binding proteins.

Cuneo MJ, Changela A, Beese LS, Hellinga HW.

J Mol Biol. 2009 May 29;389(1):157-66. doi: 10.1016/j.jmb.2009.04.008. Epub 2009 Apr 8.

PMID:
19361522
33.

Ligand-induced conformational changes in a thermophilic ribose-binding protein.

Cuneo MJ, Beese LS, Hellinga HW.

BMC Struct Biol. 2008 Nov 19;8:50. doi: 10.1186/1472-6807-8-50.

34.

Structural analysis of a periplasmic binding protein in the tripartite ATP-independent transporter family reveals a tetrameric assembly that may have a role in ligand transport.

Cuneo MJ, Changela A, Miklos AE, Beese LS, Krueger JK, Hellinga HW.

J Biol Chem. 2008 Nov 21;283(47):32812-20. doi: 10.1074/jbc.M803595200. Epub 2008 Aug 22.

35.
36.

Structure-based design of robust glucose biosensors using a Thermotoga maritima periplasmic glucose-binding protein.

Tian Y, Cuneo MJ, Changela A, Höcker B, Beese LS, Hellinga HW.

Protein Sci. 2007 Oct;16(10):2240-50. Epub 2007 Aug 31.

37.

The crystal structure of a thermophilic glucose binding protein reveals adaptations that interconvert mono and di-saccharide binding sites.

Cuneo MJ, Changela A, Warren JJ, Beese LS, Hellinga HW.

J Mol Biol. 2006 Sep 15;362(2):259-70. Epub 2006 Aug 10.

PMID:
16904687
38.
39.

Orthogonal site-specific protein modification by engineering reversible thiol protection mechanisms.

Smith JJ, Conrad DW, Cuneo MJ, Hellinga HW.

Protein Sci. 2005 Jan;14(1):64-73. Epub 2004 Dec 2.

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