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Cardiac-specific overexpression of aldehyde dehydrogenase 2 exacerbates cardiac remodeling in response to pressure overload.

Dassanayaka S, Zheng Y, Gibb AA, Cummins TD, McNally LA, Brittian KR, Jagatheesan G, Audam TN, Long BW, Brainard RE, Jones SP, Hill BG.

Redox Biol. 2018 Jul;17:440-449. doi: 10.1016/j.redox.2018.05.016. Epub 2018 Jun 1.


The DUF1669 domain of FAM83 family proteins anchor casein kinase 1 isoforms.

Fulcher LJ, Bozatzi P, Tachie-Menson T, Wu KZL, Cummins TD, Bufton JC, Pinkas DM, Dunbar K, Shrestha S, Wood NT, Weidlich S, Macartney TJ, Varghese J, Gourlay R, Campbell DG, Dingwell KS, Smith JC, Bullock AN, Sapkota GP.

Sci Signal. 2018 May 22;11(531). pii: eaao2341. doi: 10.1126/scisignal.aao2341.


PAWS1 controls Wnt signalling through association with casein kinase 1α.

Bozatzi P, Dingwell KS, Wu KZ, Cooper F, Cummins TD, Hutchinson LD, Vogt J, Wood NT, Macartney TJ, Varghese J, Gourlay R, Campbell DG, Smith JC, Sapkota GP.

EMBO Rep. 2018 Apr;19(4). pii: e44807. doi: 10.15252/embr.201744807. Epub 2018 Mar 7.


PAWS1 controls cytoskeletal dynamics and cell migration through association with the SH3 adaptor CD2AP.

Cummins TD, Wu KZL, Bozatzi P, Dingwell KS, Macartney TJ, Wood NT, Varghese J, Gourlay R, Campbell DG, Prescott A, Griffis E, Smith JC, Sapkota GP.

J Cell Sci. 2018 Jan 10;131(1). pii: jcs202390. doi: 10.1242/jcs.202390.


Characterization of Protein Complexes Using Chemical Cross-Linking Coupled Electrospray Mass Spectrometry.

Cummins TD, Sapkota GP.

Methods Mol Biol. 2018;1788:43-61. doi: 10.1007/7651_2017_85.


Allelic variation in dopamine D2 receptor gene is associated with attentional impulsiveness on the Barratt Impulsiveness Scale (BIS-11).

Taylor JB, Cummins TDR, Fox AM, Johnson BP, Tong JH, Visser TAW, Hawi Z, Bellgrove MA.

World J Biol Psychiatry. 2018;19(sup2):S75-S83. doi: 10.1080/15622975.2016.1273549. Epub 2017 Jan 20.


Separating the wheat from the chaff: systematic identification of functionally relevant noncoding variants in ADHD.

Tong JH, Hawi Z, Dark C, Cummins TD, Johnson BP, Newman DP, Lau R, Vance A, Heussler HS, Matthews N, Bellgrove MA, Pang KC.

Mol Psychiatry. 2016 Nov;21(11):1589-1598. doi: 10.1038/mp.2016.2. Epub 2016 Apr 26.


Cortical inhibitory deficits in Huntington's disease are not influenced by gender.

Philpott AL, Cummins TD, Bailey NW, Churchyard A, Fitzgerald PB, Georgiou-Karistianis N.

Psychiatry Res Neuroimaging. 2016 Nov 30;257:1-4. doi: 10.1016/j.pscychresns.2016.04.018. Epub 2016 Sep 22.


Rare DNA variants in the brain-derived neurotrophic factor gene increase risk for attention-deficit hyperactivity disorder: a next-generation sequencing study.

Hawi Z, Cummins TD, Tong J, Arcos-Burgos M, Zhao Q, Matthews N, Newman DP, Johnson B, Vance A, Heussler HS, Levy F, Easteal S, Wray NR, Kenny E, Morris D, Kent L, Gill M, Bellgrove MA.

Mol Psychiatry. 2017 Apr;22(4):580-584. doi: 10.1038/mp.2016.117. Epub 2016 Jul 26.


A GABBR2 gene variant modifies pathophysiology in Huntington's disease.

Philpott AL, Fitzgerald PB, Bailey NW, Churchyard A, Georgiou-Karistianis N, Cummins TD.

Neurosci Lett. 2016 May 4;620:8-13. doi: 10.1016/j.neulet.2016.03.038. Epub 2016 Mar 23.


Cortical inhibitory deficits in premanifest and early Huntington's disease.

Philpott AL, Cummins TDR, Bailey NW, Churchyard A, Fitzgerald PB, Georgiou-Karistianis N.

Behav Brain Res. 2016 Jan 1;296:311-317. doi: 10.1016/j.bbr.2015.09.030. Epub 2015 Sep 28.


A Population Based Study of the Genetic Association between Catecholamine Gene Variants and Spontaneous Low-Frequency Fluctuations in Reaction Time.

Bastiaansen JA, Cummins TD, Riese H, van Roon AM, Nolte IM, Oldehinkel AJ, Bellgrove MA.

PLoS One. 2015 May 15;10(5):e0126461. doi: 10.1371/journal.pone.0126461. eCollection 2015.


Identification and functional characterisation of a novel dopamine beta hydroxylase gene variant associated with attention deficit hyperactivity disorder.

Tong J, McKinley LA, Cummins TD, Johnson B, Matthews N, Vance A, Heussler H, Gill M, Kent L, Bellgrove MA, Hawi Z.

World J Biol Psychiatry. 2015;16(8):610-8. doi: 10.3109/15622975.2015.1036771. Epub 2015 May 15.


An association between a dopamine transporter gene (SLC6A3) haplotype and ADHD symptom measures in nonclinical adults.

Tong JH, Cummins TD, Johnson BP, McKinley LA, Pickering HE, Fanning P, Stefanac NR, Newman DP, Hawi Z, Bellgrove MA.

Am J Med Genet B Neuropsychiatr Genet. 2015 Mar;168B(2):89-96. doi: 10.1002/ajmg.b.32283. Epub 2015 Feb 5.


The molecular genetic architecture of attention deficit hyperactivity disorder.

Hawi Z, Cummins TD, Tong J, Johnson B, Lau R, Samarrai W, Bellgrove MA.

Mol Psychiatry. 2015 Mar;20(3):289-97. doi: 10.1038/mp.2014.183. Epub 2015 Jan 20. Review.


Dopamine transporter genotype is associated with a lateralized resistance to distraction during attention selection.

Newman DP, Cummins TD, Tong JH, Johnson BP, Pickering H, Fanning P, Wagner J, Goodrich JT, Hawi Z, Chambers CD, Bellgrove MA.

J Neurosci. 2014 Nov 19;34(47):15743-50. doi: 10.1523/JNEUROSCI.2327-14.2014.


Metabolic remodeling of white adipose tissue in obesity.

Cummins TD, Holden CR, Sansbury BE, Gibb AA, Shah J, Zafar N, Tang Y, Hellmann J, Rai SN, Spite M, Bhatnagar A, Hill BG.

Am J Physiol Endocrinol Metab. 2014 Aug 1;307(3):E262-77. doi: 10.1152/ajpendo.00271.2013. Epub 2014 Jun 10.


USP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling.

Herhaus L, Al-Salihi MA, Dingwell KS, Cummins TD, Wasmus L, Vogt J, Ewan R, Bruce D, Macartney T, Weidlich S, Smith JC, Sapkota GP.

Open Biol. 2014 May;4(5):140065. doi: 10.1098/rsob.140065.


Metabolomic analysis of pressure-overloaded and infarcted mouse hearts.

Sansbury BE, DeMartino AM, Xie Z, Brooks AC, Brainard RE, Watson LJ, DeFilippis AP, Cummins TD, Harbeson MA, Brittian KR, Prabhu SD, Bhatnagar A, Jones SP, Hill BG.

Circ Heart Fail. 2014 Jul;7(4):634-42. doi: 10.1161/CIRCHEARTFAILURE.114.001151. Epub 2014 Apr 24.


Cardiomyocyte Ogt is essential for postnatal viability.

Watson LJ, Long BW, DeMartino AM, Brittian KR, Readnower RD, Brainard RE, Cummins TD, Annamalai L, Hill BG, Jones SP.

Am J Physiol Heart Circ Physiol. 2014 Jan 1;306(1):H142-53. doi: 10.1152/ajpheart.00438.2013. Epub 2013 Nov 1.


Alpha-2A adrenergic receptor gene variants are associated with increased intra-individual variability in response time.

Cummins TD, Jacoby O, Hawi Z, Nandam LS, Byrne MA, Kim BN, Wagner J, Chambers CD, Bellgrove MA.

Mol Psychiatry. 2014 Sep;19(9):1031-6. doi: 10.1038/mp.2013.140. Epub 2013 Oct 29.


Characterization of estrogen response element binding proteins as biomarkers of breast cancer behavior.

Kruer TL, Cummins TD, Powell DW, Wittliff JL.

Clin Biochem. 2013 Nov;46(16-17):1739-46. doi: 10.1016/j.clinbiochem.2013.07.005. Epub 2013 Jul 16.


Transcranial magnetic stimulation as a tool for understanding neurophysiology in Huntington's disease: a review.

Philpott AL, Fitzgerald PB, Cummins TD, Georgiou-Karistianis N.

Neurosci Biobehav Rev. 2013 Sep;37(8):1420-33. doi: 10.1016/j.neubiorev.2013.05.009. Epub 2013 May 29. Review.


Norepinephrine genes predict response time variability and methylphenidate-induced changes in neuropsychological function in attention deficit hyperactivity disorder.

Kim BN, Kim JW, Cummins TD, Bellgrove MA, Hawi Z, Hong SB, Yang YH, Kim HJ, Shin MS, Cho SC, Kim JH, Son JW, Shin YM, Chung US, Han DH.

J Clin Psychopharmacol. 2013 Jun;33(3):356-62. doi: 10.1097/JCP.0b013e31828f9fc3.


PDGF-mediated autophagy regulates vascular smooth muscle cell phenotype and resistance to oxidative stress.

Salabei JK, Cummins TD, Singh M, Jones SP, Bhatnagar A, Hill BG.

Biochem J. 2013 May 1;451(3):375-88. doi: 10.1042/BJ20121344.


Protein O-GlcNAcylation is a novel cytoprotective signal in cardiac stem cells.

Zafir A, Readnower R, Long BW, McCracken J, Aird A, Alvarez A, Cummins TD, Li Q, Hill BG, Bhatnagar A, Prabhu SD, Bolli R, Jones SP.

Stem Cells. 2013 Apr;31(4):765-75. doi: 10.1002/stem.1325.


Utilization of fluorescent probes for the quantification and identification of subcellular proteomes and biological processes regulated by lipid peroxidation products.

Cummins TD, Higdon AN, Kramer PA, Chacko BK, Riggs DW, Salabei JK, Dell'Italia LJ, Zhang J, Darley-Usmar VM, Hill BG.

Free Radic Biol Med. 2013 Jun;59:56-68. doi: 10.1016/j.freeradbiomed.2012.08.014. Epub 2012 Aug 23.


Overexpression of endothelial nitric oxide synthase prevents diet-induced obesity and regulates adipocyte phenotype.

Sansbury BE, Cummins TD, Tang Y, Hellmann J, Holden CR, Harbeson MA, Chen Y, Patel RP, Spite M, Bhatnagar A, Hill BG.

Circ Res. 2012 Oct 12;111(9):1176-89. doi: 10.1161/CIRCRESAHA.112.266395. Epub 2012 Aug 14.


Attentional asymmetries in a visual orienting task are related to temperament.

Garner KG, Dux PE, Wagner J, Cummins TD, Chambers CD, Bellgrove MA.

Cogn Emot. 2012;26(8):1508-15. doi: 10.1080/02699931.2012.666205. Epub 2012 May 31.


The COMT Val158 allele is associated with impaired delayed-match-to-sample performance in ADHD.

Matthews N, Vance A, Cummins TD, Wagner J, Connolly A, Yamada J, Lockhart PJ, Panwar A, Wallace RH, Bellgrove MA.

Behav Brain Funct. 2012 May 28;8:25. doi: 10.1186/1744-9081-8-25.


Adolescent impulsivity phenotypes characterized by distinct brain networks.

Whelan R, Conrod PJ, Poline JB, Lourdusamy A, Banaschewski T, Barker GJ, Bellgrove MA, Büchel C, Byrne M, Cummins TD, Fauth-Bühler M, Flor H, Gallinat J, Heinz A, Ittermann B, Mann K, Martinot JL, Lalor EC, Lathrop M, Loth E, Nees F, Paus T, Rietschel M, Smolka MN, Spanagel R, Stephens DN, Struve M, Thyreau B, Vollstaedt-Klein S, Robbins TW, Schumann G, Garavan H; IMAGEN Consortium.

Nat Neurosci. 2012 Jun;15(6):920-5. doi: 10.1038/nn.3092.


Elongin C is a mediator of Notch4 activity in human renal tubule cells.

Cummins TD, Mendenhall MD, Lowry MN, Korte EA, Barati MT, Khundmiri SJ, Salyer SA, Klein JB, Powell DW.

Biochim Biophys Acta. 2011 Dec;1814(12):1748-57. doi: 10.1016/j.bbapap.2011.09.010. Epub 2011 Oct 5.


Dopamine transporter genotype predicts behavioural and neural measures of response inhibition.

Cummins TD, Hawi Z, Hocking J, Strudwick M, Hester R, Garavan H, Wagner J, Chambers CD, Bellgrove MA.

Mol Psychiatry. 2012 Nov;17(11):1086-92. doi: 10.1038/mp.2011.104. Epub 2011 Aug 30.


Val/Val genotype of brain-derived neurotrophic factor (BDNF) Val⁶⁶Met polymorphism is associated with a better response to OROS-MPH in Korean ADHD children.

Kim BN, Cummins TD, Kim JW, Bellgrove MA, Hong SB, Song SH, Shin MS, Cho SC, Kim JH, Son JW, Shin YM, Chung US, Han DH.

Int J Neuropsychopharmacol. 2011 Nov;14(10):1399-410. doi: 10.1017/S146114571100099X. Epub 2011 Jun 28.


Norepinephrine transporter -3081(A/T) and alpha-2A-adrenergic receptor MspI polymorphisms are associated with cardiovascular side effects of OROS-methylphenidate treatment.

Cho SC, Kim BN, Cummins TD, Kim JW, Bellgrove MA.

J Psychopharmacol. 2012 Mar;26(3):380-9. doi: 10.1177/0269881111405356. Epub 2011 May 31.


Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Stewart EV, Nwosu CC, Tong Z, Roguev A, Cummins TD, Kim DU, Hayles J, Park HO, Hoe KL, Powell DW, Krogan NJ, Espenshade PJ.

Mol Cell. 2011 Apr 22;42(2):160-71. doi: 10.1016/j.molcel.2011.02.035.


Blanks, a nuclear siRNA/dsRNA-binding complex component, is required for Drosophila spermiogenesis.

Gerbasi VR, Preall JB, Golden DE, Powell DW, Cummins TD, Sontheimer EJ.

Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3204-9. doi: 10.1073/pnas.1009781108. Epub 2011 Feb 7.


Methylphenidate but not atomoxetine or citalopram modulates inhibitory control and response time variability.

Nandam LS, Hester R, Wagner J, Cummins TD, Garner K, Dean AJ, Kim BN, Nathan PJ, Mattingley JB, Bellgrove MA.

Biol Psychiatry. 2011 May 1;69(9):902-4. doi: 10.1016/j.biopsych.2010.11.014. Epub 2010 Dec 30.


RASSF1A and the rs2073498 Cancer Associated SNP.

Donninger H, Barnoud T, Nelson N, Kassler S, Clark J, Cummins TD, Powell DW, Nyante S, Millikan RC, Clark GJ.

Front Oncol. 2011 Dec 28;1:54. doi: 10.3389/fonc.2011.00054. eCollection 2011.


Microfiltration isolation of human urinary exosomes for characterization by MS.

Merchant ML, Powell DW, Wilkey DW, Cummins TD, Deegens JK, Rood IM, McAfee KJ, Fleischer C, Klein E, Klein JB.

Proteomics Clin Appl. 2010 Jan;4(1):84-96. doi: 10.1002/prca.200800093. Epub 2009 Nov 11.


Identification of phosphoproteins associated with human neutrophil granules following chemotactic peptide stimulation.

Luerman GC, Powell DW, Uriarte SM, Cummins TD, Merchant ML, Ward RA, McLeish KR.

Mol Cell Proteomics. 2011 Mar;10(3):M110.001552. doi: 10.1074/mcp.M110.001552. Epub 2010 Nov 19.


ERP measures indicate both attention and working memory encoding decrements in aging.

Finnigan S, O'Connell RG, Cummins TD, Broughton M, Robertson IH.

Psychophysiology. 2011 May;48(5):601-11. doi: 10.1111/j.1469-8986.2010.01128.x. Epub 2010 Oct 5.


Quantitative mass spectrometry of diabetic kidney tubules identifies GRAP as a novel regulator of TGF-beta signaling.

Cummins TD, Barati MT, Coventry SC, Salyer SA, Klein JB, Powell DW.

Biochim Biophys Acta. 2010 Apr;1804(4):653-61. doi: 10.1016/j.bbapap.2009.09.029. Epub 2009 Oct 22.


Proteomic and functional characterisation of platelet microparticle size classes.

Dean WL, Lee MJ, Cummins TD, Schultz DJ, Powell DW.

Thromb Haemost. 2009 Oct;102(4):711-8. doi: 10.1160/TH09-04-243.


M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy.

Beck LH Jr, Bonegio RG, Lambeau G, Beck DM, Powell DW, Cummins TD, Klein JB, Salant DJ.

N Engl J Med. 2009 Jul 2;361(1):11-21. doi: 10.1056/NEJMoa0810457.


Renal tubulointerstitial fibrosis in OVE26 type 1 diabetic mice.

Powell DW, Bertram CC, Cummins TD, Barati MT, Zheng S, Epstein PN, Klein JB.

Nephron Exp Nephrol. 2009;111(1):e11-9. doi: 10.1159/000178763. Epub 2008 Dec 2.


Proteomic analysis of renal calculi indicates an important role for inflammatory processes in calcium stone formation.

Merchant ML, Cummins TD, Wilkey DW, Salyer SA, Powell DW, Klein JB, Lederer ED.

Am J Physiol Renal Physiol. 2008 Oct;295(4):F1254-8. doi: 10.1152/ajprenal.00134.2008. Epub 2008 Aug 13.


Theta oscillations are affected by amnestic mild cognitive impairment and cognitive load.

Cummins TD, Broughton M, Finnigan S.

Int J Psychophysiol. 2008 Oct;70(1):75-81. doi: 10.1016/j.ijpsycho.2008.06.002. Epub 2008 Jun 21.


Comparison of proteins expressed on secretory vesicle membranes and plasma membranes of human neutrophils.

Uriarte SM, Powell DW, Luerman GC, Merchant ML, Cummins TD, Jog NR, Ward RA, McLeish KR.

J Immunol. 2008 Apr 15;180(8):5575-81.


Use of quantitative mass spectrometry analysis in kidney research.

Cummins TD, Powell DW.

Semin Nephrol. 2007 Nov;27(6):574-83. Review.


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