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Items: 14

1.

Investigating the Behavior of Published PAINS Alerts Using a Pharmaceutical Company Data Set.

Vidler LR, Watson IA, Margolis BJ, Cummins DJ, Brunavs M.

ACS Med Chem Lett. 2018 Jul 10;9(8):792-796. doi: 10.1021/acsmedchemlett.8b00097. eCollection 2018 Aug 9.

2.

Two-Site Evaluation of the Repeatability and Precision of an Automated Dual-Column Hydrogen/Deuterium Exchange Mass Spectrometry Platform.

Cummins DJ, Espada A, Novick SJ, Molina-Martin M, Stites RE, Espinosa JF, Broughton H, Goswami D, Pascal BD, Dodge JA, Chalmers MJ, Griffin PR.

Anal Chem. 2016 Jun 21;88(12):6607-14. doi: 10.1021/acs.analchem.6b01650. Epub 2016 Jun 13.

PMID:
27224086
3.

Integrating Everything: The Molecule Selection Toolkit, a System for Compound Prioritization in Drug Discovery.

Cummins DJ, Bell MA.

J Med Chem. 2016 Aug 11;59(15):6999-7010. doi: 10.1021/acs.jmedchem.5b01338. Epub 2016 Mar 22. Review.

PMID:
26950497
4.

Selectivity data: assessment, predictions, concordance, and implications.

Gao C, Cahya S, Nicolaou CA, Wang J, Watson IA, Cummins DJ, Iversen PW, Vieth M.

J Med Chem. 2013 Sep 12;56(17):6991-7002. doi: 10.1021/jm400798j. Epub 2013 Aug 30.

PMID:
23937569
5.

Multiplex proteomic approaches to sepsis research: case studies employing new technologies.

Heuer JG, Cummins DJ, Edmonds BT.

Expert Rev Proteomics. 2005 Oct;2(5):669-80. Review.

PMID:
16209647
6.

Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease.

DeMattos RB, Bales KR, Cummins DJ, Paul SM, Holtzman DM.

Science. 2002 Mar 22;295(5563):2264-7.

7.

Neuroinflammation-induced acceleration of amyloid deposition in the APPV717F transgenic mouse.

Qiao X, Cummins DJ, Paul SM.

Eur J Neurosci. 2001 Aug;14(3):474-82.

PMID:
11553297
8.

Statistical aspects of quantitative image analysis of beta-amyloid in the APP(V717F) transgenic mouse model of Alzheimer's disease.

Fishman CE, Cummins DJ, Bales KR, DeLong CA, Esterman MA, Hanson JC, White SL, Paul SM, Jordan WH.

J Neurosci Methods. 2001 Jul 30;108(2):145-52.

PMID:
11478973
9.

Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease.

DeMattos RB, Bales KR, Cummins DJ, Dodart JC, Paul SM, Holtzman DM.

Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8850-5. Epub 2001 Jul 3.

12.

Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease.

Bales KR, Verina T, Cummins DJ, Du Y, Dodel RC, Saura J, Fishman CE, DeLong CA, Piccardo P, Petegnief V, Ghetti B, Paul SM.

Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):15233-8.

13.

Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.

Bales KR, Verina T, Dodel RC, Du Y, Altstiel L, Bender M, Hyslop P, Johnstone EM, Little SP, Cummins DJ, Piccardo P, Ghetti B, Paul SM.

Nat Genet. 1997 Nov;17(3):263-4. No abstract available.

PMID:
9354781
14.

Molecular diversity in chemical databases: comparison of medicinal chemistry knowledge bases and databases of commercially available compounds.

Cummins DJ, Andrews CW, Bentley JA, Cory M.

J Chem Inf Comput Sci. 1996 Jul-Aug;36(4):750-63.

PMID:
8768767

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