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Items: 1 to 50 of 399

1.

Antibodies from Lamprey as Smart Anti-Glycan Reagents (SAGRs)- Perspectives on their Specificity, Structure and Glyco-genomics.

McKitrick TR, Eris D, Mondal N, Aryal RP, McCurley N, Heimburg-Molinaro J, Cummings RD.

Biochemistry. 2020 Feb 13. doi: 10.1021/acs.biochem.9b01015. [Epub ahead of print]

PMID:
32052624
2.

Xenogeneic Neu5Gc and self-glycan Neu5Ac epitopes are potential immune targets in MS.

Boligan KF, Oechtering J, Keller CW, Peschke B, Rieben R, Bovin N, Kappos L, Cummings RD, Kuhle J, von Gunten S, Lünemann JD.

Neurol Neuroimmunol Neuroinflamm. 2020 Feb 3;7(2). pii: e676. doi: 10.1212/NXI.0000000000000676. Print 2020 Mar.

3.

Correction: Human IgA bind a diverse array of commensal bacteria.

Sterlin D, Fadlallah J, Adams O, Fieschi C, Parizot C, Dorgham K, Rajkumar A, Autaa G, El-Kafsi H, Charuel JL, Juste C, Jönsson F, Candela T, Wardemann H, Aubry A, Capito C, Brisson H, Tresallet C, Cummings RD, Larsen M, Yssel H, von Gunten S, Gorochov G.

J Exp Med. 2020 Mar 2;217(3). pii: e2018163501152020c. doi: 10.1084/jem.2018163501152020c. No abstract available.

PMID:
31990288
4.

Corrigendum to "Galectin-1 modulation of neutrophil reactive oxygen species production depends on the cell activation state" [Mol. Immunol. 116 (2019) 80-89].

Rodrigues LC, Kabeya LM, Azzolini AECS, Cerri DG, Stowell SR, Cummings RD, Lucisano-Valim YM, Dias-Baruffi M.

Mol Immunol. 2020 Jan 21;119:59-63. doi: 10.1016/j.molimm.2019.12.021. [Epub ahead of print] No abstract available.

PMID:
31978708
5.

A Chimeric Signal Peptide-Galectin-3 Conjugate Induces Glycosylation-Dependent Cancer Cell-Specific Apoptosis.

Van Meir EG, Lee SH, Rehman FK, Tyler KC, Yu B, Zhang Z, Zerrouqi A, Kaluzova M, Hadjipanayis CG, Cummings RD, Olson JJ, Devi NS, Osuka S.

Clin Cancer Res. 2020 Jan 22. pii: clincanres.3280.2018. doi: 10.1158/1078-0432.CCR-18-3280. [Epub ahead of print]

PMID:
31969339
6.

Better survival is observed in cervical cancer patients positive for specific anti-glycan antibodies and receiving brachytherapy.

Purohit S, Ferris DG, Alvarez M, Tran PMH, Tran LKH, Mysona DP, Hopkins D, Zhi W, Dun B, Wallbillich JJ, Cummings RD, Wang PG, She JX.

Gynecol Oncol. 2020 Jan 16. pii: S0090-8258(20)30023-8. doi: 10.1016/j.ygyno.2020.01.014. [Epub ahead of print]

PMID:
31955861
7.

Emerging patterns of tyrosine sulfation and O-glycosylation cross-talk and co-localization.

Mehta AY, Heimburg-Molinaro J, Cummings RD, Goth CK.

Curr Opin Struct Biol. 2020 Jan 9;62:102-111. doi: 10.1016/j.sbi.2019.12.002. [Epub ahead of print] Review.

PMID:
31927217
8.

Glycan Microarrays as Chemical Tools for Identifying Glycan Recognition by Immune Proteins.

Gao C, Wei M, McKitrick TR, McQuillan AM, Heimburg-Molinaro J, Cummings RD.

Front Chem. 2019 Dec 13;7:833. doi: 10.3389/fchem.2019.00833. eCollection 2019. Review.

9.

Regulation of neutrophil function by selective targeting of glycan epitopes expressed on the integrin CD11b/CD18.

Kelm M, Lehoux S, Azcutia V, Cummings RD, Nusrat A, Parkos CA, Brazil JC.

FASEB J. 2020 Feb;34(2):2326-2343. doi: 10.1096/fj.201902542R. Epub 2019 Dec 23.

PMID:
31907993
10.

Cosmc-dependent mucin-type O-linked glycosylation is essential for podocyte function.

Stotter BR, Talbot BE, Capen DE, Artelt N, Zeng J, Matsumoto Y, Endlich N, Cummings RD, Schlondorff JS.

Am J Physiol Renal Physiol. 2020 Feb 1;318(2):F518-F530. doi: 10.1152/ajprenal.00399.2019. Epub 2020 Jan 6.

PMID:
31904283
11.

Human IgA binds a diverse array of commensal bacteria.

Sterlin D, Fadlallah J, Adams O, Fieschi C, Parizot C, Dorgham K, Rajkumar A, Autaa G, El-Kafsi H, Charuel JL, Juste C, Jönsson F, Candela T, Wardemann H, Aubry A, Capito C, Brisson H, Tresallet C, Cummings RD, Larsen M, Yssel H, von Gunten S, Gorochov G.

J Exp Med. 2020 Mar 2;217(3). pii: e20181635. doi: 10.1084/jem.20181635. Erratum in: J Exp Med. 2020 Mar 2;217(3):.

12.

GlyMDB: Glycan Microarray Database and Analysis Toolset.

Cao Y, Park SJ, Mehta AY, Cummings RD, Im W.

Bioinformatics. 2019 Dec 16. pii: btz934. doi: 10.1093/bioinformatics/btz934. [Epub ahead of print]

PMID:
31841142
13.

Identification of Tn Antigen O-GalNAc-expressing glycoproteins in human carcinomas using novel anti-Tn recombinant antibodies.

Matsumoto Y, Kudelka MR, Hanes MS, Lehoux S, Dutta S, Jones MB, Stackhouse KA, Cervoni GE, Heimburg-Molinaro J, Smith DF, Ju T, Chaikof EL, Cummings RD.

Glycobiology. 2019 Nov 19. pii: cwz095. doi: 10.1093/glycob/cwz095. [Epub ahead of print]

PMID:
31742337
14.

Glycosylation of Zika Virus is Important in Host-Virus Interaction and Pathogenic Potential.

Routhu NK, Lehoux SD, Rouse EA, Bidokhti MRM, Giron LB, Anzurez A, Reid SP, Abdel-Mohsen M, Cummings RD, Byrareddy SN.

Int J Mol Sci. 2019 Oct 21;20(20). pii: E5206. doi: 10.3390/ijms20205206.

15.

Galectin-1 modulation of neutrophil reactive oxygen species production depends on the cell activation state.

Rodrigues LC, Kabeya LM, Azzolini AECS, Cerri DG, Stowell SR, Cummings RD, Lucisano-Valim YM, Dias-Baruffi M.

Mol Immunol. 2019 Dec;116:80-89. doi: 10.1016/j.molimm.2019.10.001. Epub 2019 Oct 17. Erratum in: Mol Immunol. 2020 Jan 21;119:59-63.

PMID:
31630079
16.

GlyGen: Computational and Informatics Resources for Glycoscience.

York WS, Mazumder R, Ranzinger R, Edwards N, Kahsay R, Aoki-Kinoshita KF, Campbell MP, Cummings RD, Feizi T, Martin M, Natale DA, Packer NH, Woods RJ, Agarwal G, Arpinar S, Bhat S, Blake J, Castro LJG, Fochtman B, Gildersleeve J, Goldman R, Holmes X, Jain V, Kulkarni S, Mahadik R, Mehta A, Mousavi R, Nakarakommula S, Navelkar R, Pattabiraman N, Pierce MJ, Ross K, Vasudev P, Vora J, Williamson T, Zhang W.

Glycobiology. 2020 Jan 28;30(2):72-73. doi: 10.1093/glycob/cwz080. No abstract available.

PMID:
31616925
17.

Mucin glycans attenuate the virulence of Pseudomonas aeruginosa in infection.

Wheeler KM, Cárcamo-Oyarce G, Turner BS, Dellos-Nolan S, Co JY, Lehoux S, Cummings RD, Wozniak DJ, Ribbeck K.

Nat Microbiol. 2019 Dec;4(12):2146-2154. doi: 10.1038/s41564-019-0581-8. Epub 2019 Oct 14.

PMID:
31611643
18.

Novel Reversible Fluorescent Glycan Linker for Functional Glycomics.

Wei M, McKitrick TR, Mehta AY, Gao C, Jia N, McQuillan AM, Heimburg-Molinaro J, Sun L, Cummings RD.

Bioconjug Chem. 2019 Nov 20;30(11):2897-2908. doi: 10.1021/acs.bioconjchem.9b00613. Epub 2019 Oct 25.

PMID:
31600064
19.

Natural and Synthetic Sialylated Glycan Microarrays and Their Applications.

McQuillan AM, Byrd-Leotis L, Heimburg-Molinaro J, Cummings RD.

Front Mol Biosci. 2019 Sep 13;6:88. doi: 10.3389/fmolb.2019.00088. eCollection 2019. Review.

20.

The architecture of the IgG anti-carbohydrate repertoire in primary antibody deficiencies.

Jandus P, Boligan KF, Smith DF, de Graauw E, Grimbacher B, Jandus C, Abdelhafez MM, Despont A, Bovin N, Simon D, Rieben R, Simon HU, Cummings RD, von Gunten S.

Blood. 2019 Nov 28;134(22):1941-1950. doi: 10.1182/blood.2019001705.

21.

Antigenic Pressure on H3N2 Influenza Virus Drift Strains Imposes Constraints on Binding to Sialylated Receptors but Not Phosphorylated Glycans.

Byrd-Leotis L, Gao C, Jia N, Mehta AY, Trost J, Cummings SF, Heimburg-Molinaro J, Cummings RD, Steinhauer DA.

J Virol. 2019 Oct 29;93(22). pii: e01178-19. doi: 10.1128/JVI.01178-19. Print 2019 Nov 15.

22.

The Sweet-Side of Leukocytes: Galectins as Master Regulators of Neutrophil Function.

Robinson BS, Arthur CM, Evavold B, Roback E, Kamili NA, Stowell CS, Vallecillo-Zúniga ML, Van Ry PM, Dias-Baruffi M, Cummings RD, Stowell SR.

Front Immunol. 2019 Aug 7;10:1762. doi: 10.3389/fimmu.2019.01762. eCollection 2019. Review.

23.

Cosmc is required for T cell persistence in the periphery.

Cutler CE, Jones MB, Cutler AA, Mener A, Arthur CM, Stowell SR, Cummings RD.

Glycobiology. 2019 Oct 21;29(11):776-788. doi: 10.1093/glycob/cwz054.

PMID:
31317176
24.

"Stuck on sugars - how carbohydrates regulate cell adhesion, recognition, and signaling".

Cummings RD.

Glycoconj J. 2019 Aug;36(4):241-257. doi: 10.1007/s10719-019-09876-0. Epub 2019 Jul 2.

PMID:
31267247
25.

Publisher Correction: IFN-γ-independent immune markers of Mycobacterium tuberculosis exposure.

Lu LL, Smith MT, Yu KKQ, Luedemann C, Suscovich TJ, Grace PS, Cain A, Yu WH, McKitrick TR, Lauffenburger D, Cummings RD, Mayanja-Kizza H, Hawn TR, Boom WH, Stein CM, Fortune SM, Seshadri C, Alter G.

Nat Med. 2019 Jul;25(7):1175. doi: 10.1038/s41591-019-0519-y.

PMID:
31222179
26.

Generation of fully functional hepatocyte-like organoids from human induced pluripotent stem cells mixed with Endothelial Cells.

Pettinato G, Lehoux S, Ramanathan R, Salem MM, He LX, Muse O, Flaumenhaft R, Thompson MT, Rouse EA, Cummings RD, Wen X, Fisher RA.

Sci Rep. 2019 Jun 20;9(1):8920. doi: 10.1038/s41598-019-45514-3.

27.

IFN-γ-independent immune markers of Mycobacterium tuberculosis exposure.

Lu LL, Smith MT, Yu KKQ, Luedemann C, Suscovich TJ, Grace PS, Cain A, Yu WH, McKitrick TR, Lauffenburger D, Cummings RD, Mayanja-Kizza H, Hawn TR, Boom WH, Stein CM, Fortune SM, Seshadri C, Alter G.

Nat Med. 2019 Jun;25(6):977-987. doi: 10.1038/s41591-019-0441-3. Epub 2019 May 20. Erratum in: Nat Med. 2019 Jun 20;:.

28.

Mechanisms underlying the cardiometabolic protective effect of walnut consumption in obese people: A cross-over, randomized, double-blind, controlled inpatient physiology study.

Tuccinardi D, Farr OM, Upadhyay J, Oussaada SM, Klapa MI, Candela M, Rampelli S, Lehoux S, Lázaro I, Sala-Vila A, Brigidi P, Cummings RD, Mantzoros CS.

Diabetes Obes Metab. 2019 Sep;21(9):2086-2095. doi: 10.1111/dom.13773. Epub 2019 Jul 2.

PMID:
31087608
29.

Influenza binds phosphorylated glycans from human lung.

Byrd-Leotis L, Jia N, Dutta S, Trost JF, Gao C, Cummings SF, Braulke T, Müller-Loennies S, Heimburg-Molinaro J, Steinhauer DA, Cummings RD.

Sci Adv. 2019 Feb 13;5(2):eaav2554. doi: 10.1126/sciadv.aav2554. eCollection 2019 Feb.

30.

Unique Binding Specificities of Proteins toward Isomeric Asparagine-Linked Glycans.

Gao C, Hanes MS, Byrd-Leotis LA, Wei M, Jia N, Kardish RJ, McKitrick TR, Steinhauer DA, Cummings RD.

Cell Chem Biol. 2019 Apr 18;26(4):535-547.e4. doi: 10.1016/j.chembiol.2019.01.002. Epub 2019 Feb 7.

PMID:
30745240
31.

GLAD: GLycan Array Dashboard, a visual analytics tool for glycan microarrays.

Mehta AY, Cummings RD.

Bioinformatics. 2019 Sep 15;35(18):3536-3537. doi: 10.1093/bioinformatics/btz075.

PMID:
30715201
32.

History and future of shotgun glycomics.

Smith DF, Cummings RD, Song X.

Biochem Soc Trans. 2019 Feb 28;47(1):1-11. doi: 10.1042/BST20170487. Epub 2019 Jan 9. Review.

PMID:
30626702
33.

Human B Cell Differentiation Is Characterized by Progressive Remodeling of O-Linked Glycans.

Giovannone N, Antonopoulos A, Liang J, Geddes Sweeney J, Kudelka MR, King SL, Lee GS, Cummings RD, Dell A, Barthel SR, Widlund HR, Haslam SM, Dimitroff CJ.

Front Immunol. 2018 Dec 14;9:2857. doi: 10.3389/fimmu.2018.02857. eCollection 2018.

34.

Galectin-3 aggravates experimental polymicrobial sepsis by impairing neutrophil recruitment to the infectious focus.

Ferreira RG, Rodrigues LC, Nascimento DC, Kanashiro A, Melo PH, Borges VF, Gozzi A, da Silva Prado D, Borges MC, Ramalho FS, Stowell SR, Cummings RD, Dias-Baruffi M, Cunha FQ, Alves-Filho JC.

J Infect. 2018 Nov;77(5):391-397. doi: 10.1016/j.jinf.2018.06.010. Epub 2018 Jul 4.

PMID:
30226191
35.

Differential expression of Cosmc, T-synthase and mucins in Tn-positive colorectal cancers.

Sun X, Ju T, Cummings RD.

BMC Cancer. 2018 Aug 16;18(1):827. doi: 10.1186/s12885-018-4708-8.

36.

Convergent Synthesis of Sialyl LewisX- O-Core-1 Threonine.

Sardar MYR, Mandhapati AR, Park S, Wever WJ, Cummings RD, Chaikof EL.

J Org Chem. 2018 May 4;83(9):4963-4972. doi: 10.1021/acs.joc.7b03117. Epub 2018 Apr 23.

PMID:
29638128
37.

Molecular cloning, expression, and characterization of UDP N-acetyl-α-d-galactosamine: Polypeptide N-acetylgalactosaminyltransferase 4 from Cryptosporidium parvum.

DeCicco RePass MA, Bhat N, Heimburg-Molinaro J, Bunnell S, Cummings RD, Ward HD.

Mol Biochem Parasitol. 2018 Apr;221:56-65. doi: 10.1016/j.molbiopara.2018.03.002. Epub 2018 Mar 23.

PMID:
29581010
38.

Evidence of Alternative Modes of B Cell Activation Involving Acquired Fab Regions of N-Glycosylation in Antibody-Secreting Cells Infiltrating the Labial Salivary Glands of Patients With Sjögren's Syndrome.

Koelsch KA, Cavett J, Smith K, Moore JS, Lehoux SD, Jia N, Mather T, Quadri SMS, Rasmussen A, Kaufman CE, Lewis DM, Radfar L, Scordino TA, Lessard CJ, Kurien BT, Cummings RD, James JA, Sivils KL, Farris AD, Scofield RH.

Arthritis Rheumatol. 2018 Jul;70(7):1102-1113. doi: 10.1002/art.40458. Epub 2018 May 11.

39.

Isotopic labeling with cellular O-glycome reporter/amplification (ICORA) for comparative O-glycomics of cultured cells.

Kudelka MR, Nairn AV, Sardar MY, Sun X, Chaikof EL, Ju T, Moremen KW, Cummings RD.

Glycobiology. 2018 Apr 1;28(4):214-222. doi: 10.1093/glycob/cwy005.

40.

Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins.

Purohit S, Li T, Guan W, Song X, Song J, Tian Y, Li L, Sharma A, Dun B, Mysona D, Ghamande S, Rungruang B, Cummings RD, Wang PG, She JX.

Nat Commun. 2018 Jan 17;9(1):258. doi: 10.1038/s41467-017-02747-y.

41.

A comprehensive Caenorhabditis elegans N-glycan shotgun array.

Jankowska E, Parsons LM, Song X, Smith DF, Cummings RD, Cipollo JF.

Glycobiology. 2018 Apr 1;28(4):223-232. doi: 10.1093/glycob/cwy002.

42.

The Mannose Receptor in Regulation of Helminth-Mediated Host Immunity.

van Die I, Cummings RD.

Front Immunol. 2017 Nov 29;8:1677. doi: 10.3389/fimmu.2017.01677. eCollection 2017. Review.

43.

The Haystack Is Full of Needles: Technology Rescues Sugars!

Cummings RD.

Mol Cell. 2017 Dec 7;68(5):827-829. doi: 10.1016/j.molcel.2017.11.024.

44.

Proteomic and functional analysis identifies galectin-1 as a novel regulatory component of the cytotoxic granule machinery.

Clemente T, Vieira NJ, Cerliani JP, Adrain C, Luthi A, Dominguez MR, Yon M, Barrence FC, Riul TB, Cummings RD, Zorn TM, Amigorena S, Dias-Baruffi M, Rodrigues MM, Martin SJ, Rabinovich GA, Amarante-Mendes GP.

Cell Death Dis. 2017 Dec 7;8(12):e3176. doi: 10.1038/cddis.2017.506.

45.

A library of chemically defined human N-glycans synthesized from microbial oligosaccharide precursors.

Hamilton BS, Wilson JD, Shumakovich MA, Fisher AC, Brooks JC, Pontes A, Naran R, Heiss C, Gao C, Kardish R, Heimburg-Molinaro J, Azadi P, Cummings RD, Merritt JH, DeLisa MP.

Sci Rep. 2017 Nov 21;7(1):15907. doi: 10.1038/s41598-017-15891-8.

46.

Synthesis of LewisX-O-Core-1 threonine: A building block for O-linked LewisX glycopeptides.

Sardar MYR, Krishnamurthy VR, Park S, Mandhapati AR, Wever WJ, Park D, Cummings RD, Chaikof EL.

Carbohydr Res. 2017 Nov 27;452:47-53. doi: 10.1016/j.carres.2017.10.002. Epub 2017 Oct 10.

47.

Structural Insights into VLR Fine Specificity for Blood Group Carbohydrates.

Collins BC, Gunn RJ, McKitrick TR, Cummings RD, Cooper MD, Herrin BR, Wilson IA.

Structure. 2017 Nov 7;25(11):1667-1678.e4. doi: 10.1016/j.str.2017.09.003. Epub 2017 Oct 5.

48.

Various N-glycoforms differentially upregulate E-NTPDase activity of the NTPDase3/CD39L3 ecto-enzymatic domain.

Zhong AH, Gordon Jiang Z, Cummings RD, Robson SC.

Purinergic Signal. 2017 Dec;13(4):601-609. doi: 10.1007/s11302-017-9587-y. Epub 2017 Sep 27.

49.

GlyTouCan: an accessible glycan structure repository.

Tiemeyer M, Aoki K, Paulson J, Cummings RD, York WS, Karlsson NG, Lisacek F, Packer NH, Campbell MP, Aoki NP, Fujita A, Matsubara M, Shinmachi D, Tsuchiya S, Yamada I, Pierce M, Ranzinger R, Narimatsu H, Aoki-Kinoshita KF.

Glycobiology. 2017 Oct 1;27(10):915-919. doi: 10.1093/glycob/cwx066.

50.

Principles of Glycan Recognition.

Cummings RD, Schnaar RL, Esko JD, Drickamer K, Taylor ME.

In: Varki A, Cummings RD, Esko JD, Stanley P, Hart GW, Aebi M, Darvill AG, Kinoshita T, Packer NH, Prestegard JH, Schnaar RL, Seeberger PH, editors. Essentials of Glycobiology [Internet]. 3rd edition. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2015-2017. Chapter 29.
2017.

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