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Items: 1 to 50 of 65

1.

Nephrotoxicity and Renal Pathophysiology: A Contemporary Perspective.

Barnett LMA, Cummings BS.

Toxicol Sci. 2018 Jun 25. doi: 10.1093/toxsci/kfy159. [Epub ahead of print]

PMID:
29939355
2.

Toxicokinetics of Deltamethrin: Dosage Dependency, Vehicle Effects, and Low-Dose Age-Equivalent Dosimetry in Rats.

Mortuza T, Chen C, White CA, Cummings BS, Muralidhara S, Gullick D, Bruckner JV.

Toxicol Sci. 2018 Mar 1;162(1):327-336. doi: 10.1093/toxsci/kfx260.

PMID:
29165640
3.

Effects of high-fat diet and age on the blood lipidome and circulating endocannabinoids of female C57BL/6 mice.

Pati S, Krishna S, Lee JH, Ross MK, de La Serre CB, Harn DA Jr, Wagner JJ, Filipov NM, Cummings BS.

Biochim Biophys Acta. 2018 Jan;1863(1):26-39. doi: 10.1016/j.bbalip.2017.09.011. Epub 2017 Oct 4.

PMID:
28986283
4.

Brain uptake of deltamethrin in rats as a function of plasma protein binding and blood-brain barrier maturation.

Amaraneni M, Pang J, Mortuza TB, Muralidhara S, Cummings BS, White CA, Vorhees CV, Zastre J, Bruckner JV.

Neurotoxicology. 2017 Sep;62:24-29. doi: 10.1016/j.neuro.2017.04.009. Epub 2017 May 8.

PMID:
28495520
5.

Influence of Maturation on In Vivo Tissue to Plasma Partition Coefficients for Cis- and Trans-Permethrin.

Amaraneni M, Pang J, Bruckner JV, Muralidhara S, Mortuza TB, Gullick D, Hooshfar S, White CA, Cummings BS.

J Pharm Sci. 2017 Aug;106(8):2144-2151. doi: 10.1016/j.xphs.2017.04.024. Epub 2017 Apr 23.

PMID:
28445697
6.

Nephrotoxicity of epigenetic inhibitors used for the treatment of cancer.

Scholpa NE, Kolli RT, Moore M, Arnold RD, Glenn TC, Cummings BS.

Chem Biol Interact. 2016 Oct 25;258:21-9. doi: 10.1016/j.cbi.2016.08.010. Epub 2016 Aug 16.

7.

The immature rat as a potential model for chemical risks to children: Ontogeny of selected hepatic P450s.

McPhail BT, White CA, Cummings BS, Muralidhara S, Wilson JT, Bruckner JV.

Chem Biol Interact. 2016 Aug 25;256:167-77. doi: 10.1016/j.cbi.2016.07.005. Epub 2016 Jul 5.

PMID:
27387539
8.

Plasma protein binding limits the blood brain barrier permeation of the pyrethroid insecticide, deltamethrin.

Amaraneni M, Sharma A, Pang J, Muralidhara S, Cummings BS, White CA, Bruckner JV, Zastre J.

Toxicol Lett. 2016 May 27;250-251:21-8. doi: 10.1016/j.toxlet.2016.03.006. Epub 2016 Mar 22.

PMID:
27016408
9.

Liposome-mediated delivery of the p21 activated kinase-1 (PAK-1) inhibitor IPA-3 limits prostate tumor growth in vivo.

Al-Azayzih A, Missaoui WN, Cummings BS, Somanath PR.

Nanomedicine. 2016 Jul;12(5):1231-1239. doi: 10.1016/j.nano.2016.01.003. Epub 2016 Mar 3.

10.

Cyclin-Dependent Kinase Inhibitor 1a (p21) Modulates Response to Cocaine and Motivated Behaviors.

Scholpa NE, Briggs SB, Wagner JJ, Cummings BS.

J Pharmacol Exp Ther. 2016 Apr;357(1):56-65. doi: 10.1124/jpet.115.230888. Epub 2016 Jan 20.

11.

Extraction, chromatographic and mass spectrometric methods for lipid analysis.

Pati S, Nie B, Arnold RD, Cummings BS.

Biomed Chromatogr. 2016 May;30(5):695-709. doi: 10.1002/bmc.3683. Epub 2016 Feb 18. Review.

PMID:
26762903
12.

Ontogeny of plasma proteins, albumin and binding of diazepam, cyclosporine, and deltamethrin.

Sethi PK, White CA, Cummings BS, Hines RN, Muralidhara S, Bruckner JV.

Pediatr Res. 2016 Mar;79(3):409-15. doi: 10.1038/pr.2015.237. Epub 2015 Nov 16.

PMID:
26571224
13.

Differential effects of cocaine exposure on the abundance of phospholipid species in rat brain and blood.

Cummings BS, Pati S, Sahin S, Scholpa NE, Monian P, Trinquero PM, Clark JK, Wagner JJ.

Drug Alcohol Depend. 2015 Jul 1;152:147-56. doi: 10.1016/j.drugalcdep.2015.04.009. Epub 2015 Apr 22.

14.

Role of the phospholipase A2 receptor in liposome drug delivery in prostate cancer cells.

Quach ND, Mock JN, Scholpa NE, Eggert MW, Payré C, Lambeau G, Arnold RD, Cummings BS.

Mol Pharm. 2014 Oct 6;11(10):3443-51. doi: 10.1021/mp500174p. Epub 2014 Sep 22.

15.

ERK oscillation-dependent gene expression patterns and deregulation by stress response.

Waters KM, Cummings BS, Shankaran H, Scholpa NE, Weber TJ.

Chem Res Toxicol. 2014 Sep 15;27(9):1496-503. doi: 10.1021/tx500085u. Epub 2014 Aug 12.

16.

Epigenetic changes in p21 expression in renal cells after exposure to bromate.

Scholpa NE, Zhang X, Kolli RT, Cummings BS.

Toxicol Sci. 2014 Oct;141(2):432-40. doi: 10.1093/toxsci/kfu138. Epub 2014 Jul 11.

17.

Secretory phospholipase A2 enzymes as pharmacological targets for treatment of disease.

Quach ND, Arnold RD, Cummings BS.

Biochem Pharmacol. 2014 Aug 15;90(4):338-48. doi: 10.1016/j.bcp.2014.05.022. Epub 2014 Jun 4. Review.

18.

Determination of deltamethrin in rat plasma and brain using gas chromatography-negative chemical ionization mass spectrometry.

Gullick D, Popovici A, Young HC, Bruckner JV, Cummings BS, Li P, Bartlett MG.

J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Jun 1;960:158-65. doi: 10.1016/j.jchromb.2014.04.008. Epub 2014 Apr 13.

PMID:
24814001
19.

Ion exchange liquid chromatography method for the direct determination of small ribonucleic acids.

McGinnis AC, Cummings BS, Bartlett MG.

Anal Chim Acta. 2013 Oct 17;799:57-67. doi: 10.1016/j.aca.2013.08.040. Epub 2013 Aug 31.

PMID:
24091375
20.

Association of brominated proteins and changes in protein expression in the rat kidney with subcarcinogenic to carcinogenic doses of bromate.

Kolisetty N, Bull RJ, Muralidhara S, Costyn LJ, Delker DA, Guo Z, Cotruvo JA, Fisher JW, Cummings BS.

Toxicol Appl Pharmacol. 2013 Oct 15;272(2):391-8. doi: 10.1016/j.taap.2013.06.018. Epub 2013 Jun 26.

PMID:
23811332
21.

Changes in mRNA and protein expression in the renal cortex of male and female F344 rats treated with bromate.

Kolisetty N, Delker DA, Muralidhara S, Bull RJ, Cotruvo JA, Fisher JW, Cummings BS.

Arch Toxicol. 2013 Nov;87(11):1911-1925. doi: 10.1007/s00204-013-1052-2. Epub 2013 Apr 16.

PMID:
23588252
22.

Lead at 2.5 and 5.0 μM induced aberrant MH-II surface expression through increased MII exocytosis and increased autophagosome formation in Raw 267.4 cells.

Kerr RP, Krunkosky TM, Hurley DJ, Cummings BS, Holladay SD, Gogal RM Jr.

Toxicol In Vitro. 2013 Apr;27(3):1018-24. doi: 10.1016/j.tiv.2013.01.018. Epub 2013 Jan 31.

PMID:
23376802
23.

Evidence for distinct mechanisms of uptake and antitumor activity of secretory phospholipase A2 responsive liposome in prostate cancer.

Mock JN, Costyn LJ, Wilding SL, Arnold RD, Cummings BS.

Integr Biol (Camb). 2013 Jan;5(1):172-82. doi: 10.1039/c2ib20108a.

24.

Absorption and disposition of bromate in F344 rats.

Bull RJ, Kolisetty N, Zhang X, Muralidhara S, Quiñones O, Lim KY, Guo Z, Cotruvo JA, Fisher JW, Yang X, Delker D, Snyder SA, Cummings BS.

Toxicology. 2012 Oct 9;300(1-2):83-91. doi: 10.1016/j.tox.2012.06.002. Epub 2012 Jun 12.

PMID:
22699156
25.

Haloenol pyranones and morpholinones as antineoplastic agents of prostate cancer.

Mock JN, Taliaferro JP, Lu X, Patel SK, Cummings BS, Long TE.

Bioorg Med Chem Lett. 2012 Jul 15;22(14):4854-8. doi: 10.1016/j.bmcl.2012.05.038. Epub 2012 May 17.

26.

The role of endoplasmic reticulum Ca2+-independent phospholipase a2γ in oxidant-induced lipid peroxidation, Ca2+ release, and renal cell death.

Eaddy AC, Cummings BS, McHowat J, Schnellmann RG.

Toxicol Sci. 2012 Aug;128(2):544-52. doi: 10.1093/toxsci/kfs175. Epub 2012 May 12.

27.

Measurement of cell death in Mammalian cells.

Cummings BS, Wills LP, Schnellmann RG.

Curr Protoc Pharmacol. 2012 Mar;Chapter 12:Unit12.8. doi: 10.1002/0471141755.ph1208s56.

PMID:
22382997
28.

Synthesis of lipids for development of multifunctional lipid-based drug-carriers.

Zhu G, Alhamhoom Y, Cummings BS, Arnold RD.

Bioorg Med Chem Lett. 2011 Nov 1;21(21):6370-5. doi: 10.1016/j.bmcl.2011.08.103. Epub 2011 Sep 8.

29.

The synergistic effect of sodium chlorite and bromochloroacetic acid on BrO3(-)-induced renal cell death.

Zhang X, Bull RJ, Fisher J, Cotruvo JA, Cummings BS.

Toxicology. 2011 Nov 18;289(2-3):151-9. doi: 10.1016/j.tox.2011.08.008. Epub 2011 Aug 16.

PMID:
21864635
30.

Enhanced antitumor activity of low-dose continuous administration schedules of topotecan in prostate cancer.

Aljuffali IA, Mock JN, Costyn LJ, Nguyen H, Nagy T, Cummings BS, Arnold RD.

Cancer Biol Ther. 2011 Sep 1;12(5):407-20. Epub 2011 Sep 1.

31.

Secretory phospholipase A₂ responsive liposomes.

Zhu G, Mock JN, Aljuffali I, Cummings BS, Arnold RD.

J Pharm Sci. 2011 Aug;100(8):3146-3159. doi: 10.1002/jps.22530. Epub 2011 Mar 31.

32.

Profiling of fatty acids released during calcium-induced mitochondrial permeability transition in isolated rabbit kidney cortex mitochondria.

Blum JL, Kinsey GR, Monian P, Sun B, Cummings BS, McHowat J, Schnellmann RG.

Toxicol In Vitro. 2011 Aug;25(5):1001-6. doi: 10.1016/j.tiv.2011.03.014. Epub 2011 Apr 3.

33.

Bax regulates production of superoxide in both apoptotic and nonapoptotic neurons: role of caspases.

Kirkland RA, Saavedra GM, Cummings BS, Franklin JL.

J Neurosci. 2010 Dec 1;30(48):16114-27. doi: 10.1523/JNEUROSCI.2862-10.2010.

34.

Drug-induced hemolytic anemia and thrombocytopenia associated with alterations of cell membrane lipids and acanthocyte formation.

Poulet FM, Penraat K, Collins N, Evans E, Thackaberry E, Manfra D, Engstrom L, Geissler R, Geraci-Erck M, Frugone C, Abutarif M, Fine JS, Peterson BL, Cummings BS, Johnson RC.

Toxicol Pathol. 2010 Oct;38(6):907-22. doi: 10.1177/0192623310378865. Epub 2010 Aug 30.

PMID:
20805317
35.

Inhibition of calcium-independent phospholipase A2 activates p38 MAPK signaling pathways during cytostasis in prostate cancer cells.

Sun B, Zhang X, Yonz C, Cummings BS.

Biochem Pharmacol. 2010 Jun 15;79(12):1727-35. doi: 10.1016/j.bcp.2010.02.005. Epub 2010 Feb 18.

PMID:
20171194
36.

Cellular and molecular mechanisms of bromate-induced cytotoxicity in human and rat kidney cells.

Zhang X, De Silva D, Sun B, Fisher J, Bull RJ, Cotruvo JA, Cummings BS.

Toxicology. 2010 Feb 28;269(1):13-23. doi: 10.1016/j.tox.2010.01.002. Epub 2010 Jan 11.

PMID:
20067818
37.

Characterization of human lysophospholipid acyltransferase 3.

Jain S, Zhang X, Khandelwal PJ, Saunders AJ, Cummings BS, Oelkers P.

J Lipid Res. 2009 Aug;50(8):1563-70. doi: 10.1194/jlr.M800398-JLR200. Epub 2009 Apr 7.

38.

Role of Ca2+-independent phospholipase A2 in cell growth and signaling.

Hooks SB, Cummings BS.

Biochem Pharmacol. 2008 Oct 30;76(9):1059-67. doi: 10.1016/j.bcp.2008.07.044. Epub 2008 Aug 15. Review.

39.

Alterations in phospholipid and fatty acid lipid profiles in primary neocortical cells during oxidant-induced cell injury.

Peterson B, Stovall K, Monian P, Franklin JL, Cummings BS.

Chem Biol Interact. 2008 Aug 11;174(3):163-76. doi: 10.1016/j.cbi.2008.05.028. Epub 2008 May 29.

PMID:
18602625
40.

Inhibition of Ca2+-independent phospholipase A2 decreases prostate cancer cell growth by p53-dependent and independent mechanisms.

Sun B, Zhang X, Talathi S, Cummings BS.

J Pharmacol Exp Ther. 2008 Jul;326(1):59-68. doi: 10.1124/jpet.108.138958. Epub 2008 Apr 25.

41.

Decreased iPLA2gamma expression induces lipid peroxidation and cell death and sensitizes cells to oxidant-induced apoptosis.

Kinsey GR, Blum JL, Covington MD, Cummings BS, McHowat J, Schnellmann RG.

J Lipid Res. 2008 Jul;49(7):1477-87. doi: 10.1194/jlr.M800030-JLR200. Epub 2008 Apr 8.

42.

Identification, coassembly, and activity of gamma-aminobutyric acid receptor subunits in renal proximal tubular cells.

Sarang SS, Lukyanova SM, Brown DD, Cummings BS, Gullans SR, Schnellmann RG.

J Pharmacol Exp Ther. 2008 Jan;324(1):376-82. Epub 2007 Oct 24.

43.

Phospholipase A2 as targets for anti-cancer drugs.

Cummings BS.

Biochem Pharmacol. 2007 Oct 1;74(7):949-59. Epub 2007 Apr 27. Review.

PMID:
17531957
44.

Involvement of Ca2+-independent phospholipase A2 isoforms in oxidant-induced neural cell death.

Peterson B, Knotts T, Cummings BS.

Neurotoxicology. 2007 Jan;28(1):150-60. Epub 2006 Sep 16.

PMID:
17046062
45.

Differential roles for cytosolic and microsomal Ca2+-independent phospholipase A2 in cell growth and maintenance of phospholipids.

Saavedra G, Zhang W, Peterson B, Cummings BS.

J Pharmacol Exp Ther. 2006 Sep;318(3):1211-9. Epub 2006 Jun 8.

46.

A novel role for calcium-independent phospholipase A in alpha-amino-3-hydroxy-5-methylisoxazole-propionate receptor regulation during long-term potentiation.

Martel MA, Patenaude C, Ménard C, Alaux S, Cummings BS, Massicotte G.

Eur J Neurosci. 2006 Jan;23(2):505-13.

PMID:
16420457
47.

The effect of inhibition of Ca2+-independent phospholipase A2 on chemotherapeutic-induced death and phospholipid profiles in renal cells.

Zhang L, Peterson BL, Cummings BS.

Biochem Pharmacol. 2005 Nov 25;70(11):1697-706. Epub 2005 Oct 13.

PMID:
16226224
48.

A review of chromatographic methods for the assessment of phospholipids in biological samples.

Peterson BL, Cummings BS.

Biomed Chromatogr. 2006 Mar;20(3):227-43. Review.

PMID:
16138296
49.

Identification and distribution of endoplasmic reticulum iPLA2.

Kinsey GR, Cummings BS, Beckett CS, Saavedra G, Zhang W, McHowat J, Schnellmann RG.

Biochem Biophys Res Commun. 2005 Feb 4;327(1):287-93.

PMID:
15629460
50.

Measurement of cell death in mammalian cells.

Cummings BS, Schnellmann RG.

Curr Protoc Pharmacol. 2004 Sep 1;Chapter 12:Unit 12.8. doi: 10.1002/0471141755.ph1208s25.

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