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Items: 1 to 50 of 522

1.

Repeated Mild Closed Head Injuries Induce Long-Term White Matter Pathology and Neuronal Loss That Are Correlated With Behavioral Deficits.

Gold EM, Vasilevko V, Hasselmann J, Tiefenthaler C, Hoa D, Ranawaka K, Cribbs DH, Cummings BJ.

ASN Neuro. 2018 Jan-Dec;10:1759091418781921. doi: 10.1177/1759091418781921.

PMID:
29932344
2.

Local Immunomodulation with Anti-inflammatory Cytokine-Encoding Lentivirus Enhances Functional Recovery after Spinal Cord Injury.

Park J, Decker JT, Margul DJ, Smith DR, Cummings BJ, Anderson AJ, Shea LD.

Mol Ther. 2018 Apr 27. pii: S1525-0016(18)30200-4. doi: 10.1016/j.ymthe.2018.04.022. [Epub ahead of print]

PMID:
29778523
3.

Approaches to parental demand for non-established medical treatment: reflections on the Charlie Gard case.

Paris JJ, Cummings BM, Moreland MP, Batten JN.

J Med Ethics. 2018 May 18. pii: medethics-2018-104902. doi: 10.1136/medethics-2018-104902. [Epub ahead of print] No abstract available.

PMID:
29776977
4.

The ongoing challenge of large anal cancers: prospective long term outcomes of intensity-modulated radiation therapy with concurrent chemotherapy.

Hosni A, Han K, Le LW, Ringash J, Brierley J, Wong R, Dinniwell R, Brade A, Dawson LA, Cummings BJ, Krzyzanowska MK, Chen EX, Hedley D, Knox J, Easson AM, Lindsay P, Craig T, Kim J.

Oncotarget. 2018 Apr 17;9(29):20439-20450. doi: 10.18632/oncotarget.24926. eCollection 2018 Apr 17.

5.

β Cell GLP-1R Signaling Alters α Cell Proglucagon Processing after Vertical Sleeve Gastrectomy in Mice.

Garibay D, Lou J, Lee SA, Zaborska KE, Weissman MH, Sloma E, Donahue L, Miller AD, White AC, Michael MD, Sloop KW, Cummings BP.

Cell Rep. 2018 Apr 24;23(4):967-973. doi: 10.1016/j.celrep.2018.03.120.

6.

Congenital titinopathy: Comprehensive characterisation and pathogenic insights.

Oates EC, Jones KJ, Donkervoort S, Charlton A, Brammah S, Smith JE 3rd, Ware JS, Yau KS, Swanson LC, Whiffin N, Peduto AJ, Bournazos A, Waddell LB, Farrar MA, Sampaio HA, Teoh HL, Lamont PJ, Mowat D, Fitzsimons RB, Corbett AJ, Ryan MM, O'Grady GL, Sandaradura SA, Ghaoui R, Joshi HB, Marshall JL, Nolan MA, Kaur S, Punetha J, Töpf A, Harris E, Bakshi M, Genetti CA, Marttila M, Werlauff U, Streichenberger N, Pestronk A, Mazanti I, Pinner JR, Vuillerot C, Grosmann C, Camacho A, Mohassel P, Leach ME, Foley AR, Bharucha-Goebel D, Collins J, Connolly AM, Gilbreath HR, Iannaccone ST, Castro D, Cummings BB, Webster RI, Lazaro L, Vissing J, Coppens S, Deconinck N, Luk HM, Thomas NH, Foulds NC, Illingworth MA, Ellard S, McLean CA, Phadke R, Ravenscroft G, Witting N, Hackman P, Richard I, Cooper ST, Kamsteeg EJ, Hoffman EP, Bushby K, Straub V, Udd B, Ferreiro A, North KN, Clarke NF, Lek M, Beggs AH, Bönnemann CG, MacArthur DG, Granzier H, Davis MR, Laing NG.

Ann Neurol. 2018 Apr 25. doi: 10.1002/ana.25241. [Epub ahead of print]

PMID:
29691892
7.

Transition to a new electronic health record and pediatric medication safety: lessons learned in pediatrics within a large academic health system.

Whalen K, Lynch E, Moawad I, John T, Lozowski D, Cummings BM.

J Am Med Inform Assoc. 2018 Apr 23. doi: 10.1093/jamia/ocy034. [Epub ahead of print]

PMID:
29688461
8.

Characteristics of Volunteer Coaches in a Clinical Process Improvement Program.

Morley KE, Barysauskas CM, Carballo V, Kalibatas O, Rao SK, Jacobson JO, Cummings BM.

Qual Manag Health Care. 2018 Apr/Jun;27(2):81-86. doi: 10.1097/QMH.0000000000000163.

PMID:
29596268
9.

Corrigendum: Landscape of X chromosome inactivation across human tissues.

Tukiainen T, Villani AC, Yen A, Rivas MA, Marshall JL, Satija R, Aguirre M, Gauthier L, Fleharty M, Kirby A, Cummings BB, Castel SE, Karczewski KJ, Aguet F, Byrnes A, Consortium G, Lappalainen T, Regev A, Ardlie KG, Hacohen N, MacArthur DG.

Nature. 2018 Mar 7;555(7695):274. doi: 10.1038/nature25993.

PMID:
29517003
10.

A gastronomic delight?

Soriano LF, Cummings B, Jolliffe V.

Dermatol Online J. 2017 Oct 15;23(10). pii: 13030/qt28d5d695.

PMID:
29469797
11.

Longshot, Fantasy, and Pipedreams.

Paris JJ, Cummings BM.

Am J Bioeth. 2018 Jan;18(1):19-21. doi: 10.1080/15265161.2017.1411082. No abstract available.

PMID:
29313793
12.

A Murine Model of Vertical Sleeve Gastrectomy.

Garibay D, Cummings BP.

J Vis Exp. 2017 Dec 18;(130). doi: 10.3791/56534.

PMID:
29286478
13.

Nemaline myopathy and distal arthrogryposis associated with an autosomal recessive TNNT3 splice variant.

Sandaradura SA, Bournazos A, Mallawaarachchi A, Cummings BB, Waddell LB, Jones KJ, Troedson C, Sudarsanam A, Nash BM, Peters GB, Algar EM, MacArthur DG, North KN, Brammah S, Charlton A, Laing NG, Wilson MJ, Davis MR, Cooper ST.

Hum Mutat. 2018 Mar;39(3):383-388. doi: 10.1002/humu.23385. Epub 2018 Jan 13.

PMID:
29266598
14.

Bisexual and Bidirectional: Assessing the Potential for HIV Bridging in Mozambique.

Cummings B, Horth R, McFarland W, Lane T, Young PW, Nalá R, Rutherford G, Raymond HF.

AIDS Behav. 2017 Nov 29. doi: 10.1007/s10461-017-1994-0. [Epub ahead of print]

PMID:
29188391
15.

Toxicokinetics of Deltamethrin: Dosage Dependency, Vehicle Effects, and Low-Dose Age-Equivalent Dosimetry in Rats.

Mortuza T, Chen C, White CA, Cummings BS, Muralidhara S, Gullick D, Bruckner JV.

Toxicol Sci. 2018 Mar 1;162(1):327-336. doi: 10.1093/toxsci/kfx260.

PMID:
29165640
16.

Case 33-2017. 22-Month-Old Conjoined Twins.

Cummings BM, Gee MS, Benavidez OJ, Shank ES, Bojovic B, Raskin KA, Goldstein AM.

N Engl J Med. 2017 Oct 26;377(17):1667-1677. doi: 10.1056/NEJMcpc1706105. No abstract available.

PMID:
29069560
17.

Live-cell time-lapse imaging and single-cell tracking of in vitro cultured neural stem cells - Tools for analyzing dynamics of cell cycle, migration, and lineage selection.

Piltti KM, Cummings BJ, Carta K, Manughian-Peter A, Worne CL, Singh K, Ong D, Maksymyuk Y, Khine M, Anderson AJ.

Methods. 2018 Jan 15;133:81-90. doi: 10.1016/j.ymeth.2017.10.003. Epub 2017 Oct 16.

PMID:
29050826
18.

The Charlie Gard case: British and American approaches to court resolution of disputes over medical decisions.

Paris JJ, Ahluwalia J, Cummings BM, Moreland MP, Wilkinson DJ.

J Perinatol. 2017 Dec;37(12):1268-1271. doi: 10.1038/jp.2017.138. Epub 2017 Oct 19. No abstract available.

19.

Landscape of X chromosome inactivation across human tissues.

Tukiainen T, Villani AC, Yen A, Rivas MA, Marshall JL, Satija R, Aguirre M, Gauthier L, Fleharty M, Kirby A, Cummings BB, Castel SE, Karczewski KJ, Aguet F, Byrnes A; GTEx Consortium; Laboratory, Data Analysis &Coordinating Center (LDACC)—Analysis Working Group; Statistical Methods groups—Analysis Working Group; Enhancing GTEx (eGTEx) groups; NIH Common Fund; NIH/NCI; NIH/NHGRI; NIH/NIMH; NIH/NIDA; Biospecimen Collection Source Site—NDRI; Biospecimen Collection Source Site—RPCI; Biospecimen Core Resource—VARI; Brain Bank Repository—University of Miami Brain Endowment Bank; Leidos Biomedical—Project Management; ELSI Study; Genome Browser Data Integration &Visualization—EBI; Genome Browser Data Integration &Visualization—UCSC Genomics Institute, University of California Santa Cruz, Lappalainen T, Regev A, Ardlie KG, Hacohen N, MacArthur DG.

Nature. 2017 Oct 11;550(7675):244-248. doi: 10.1038/nature24265. Erratum in: Nature. 2018 Mar 7;555(7695):274.

20.

Effects of high-fat diet and age on the blood lipidome and circulating endocannabinoids of female C57BL/6 mice.

Pati S, Krishna S, Lee JH, Ross MK, de La Serre CB, Harn DA Jr, Wagner JJ, Filipov NM, Cummings BS.

Biochim Biophys Acta. 2018 Jan;1863(1):26-39. doi: 10.1016/j.bbalip.2017.09.011. Epub 2017 Oct 4.

PMID:
28986283
21.

Approaches to end-of-life discussions with parents of a profoundly compromised newborn.

Paris JJ, Pai V, Cummings BM, Batten J, Benitz WE.

J Perinatol. 2017 Oct;37(10):1078-1081. doi: 10.1038/jp.2017.77. No abstract available.

PMID:
28984877
22.

Effects of Human ES-Derived Neural Stem Cell Transplantation and Kindling in a Rat Model of Traumatic Brain Injury.

Beretta S, Cunningham KM, Haus DL, Gold EM, Perez H, López-Velázquez L, Cummings BJ.

Cell Transplant. 2017 Jul;26(7):1247-1261. doi: 10.1177/0963689717714107.

23.

Impact of Pediatric Intensive Care Unit Admission on Family Financial Status and Productivity: A Pilot Study.

Clark ME, Cummings BM, Kuhlthau K, Frassica N, Noviski N.

J Intensive Care Med. 2017 Jan 1:885066617723278. doi: 10.1177/0885066617723278. [Epub ahead of print]

PMID:
28797189
24.

Impact of SIGN guideline thresholds for DXA access for patients referred to direct access DXA: implications for clinical practice?

Wilson C, Loughrey PB, Cummings B, McNally C, Lindsay JR.

Osteoporos Int. 2017 Nov;28(11):3281-3282. doi: 10.1007/s00198-017-4168-z. Epub 2017 Aug 4. No abstract available.

PMID:
28776184
25.

The Steinberg Centre for Simulation and Interactive Learning at McGill University.

Mueller CL, Cyr G, Bank I, Bhanji F, Birnbaum L, Boillat M, Bolduc ME, Chankowsky J, Constantin E, Cummings BA, Fisher R, Legault P, Hugo Marchand N, Monton L, Rudkin T, Sabsabi B, Soilis N, Zigman D, Aggarwal R.

J Surg Educ. 2017 Nov - Dec;74(6):1135-1141. doi: 10.1016/j.jsurg.2017.05.022. Epub 2017 Jul 5.

PMID:
28688969
26.

Neutrophils Induce Astroglial Differentiation and Migration of Human Neural Stem Cells via C1q and C3a Synthesis.

Hooshmand MJ, Nguyen HX, Piltti KM, Benavente F, Hong S, Flanagan L, Uchida N, Cummings BJ, Anderson AJ.

J Immunol. 2017 Aug 1;199(3):1069-1085. doi: 10.4049/jimmunol.1600064. Epub 2017 Jul 7.

27.

Novel Noninvasive Method of Cerebrovascular Blood Volume Assessment Using Brain Bioimpedance.

Tiba MH, McCracken BM, Ansari S, Belle A, Cummings BC, Rajajee V, Patil PG, Alam HB, Ward KR.

J Neurotrauma. 2017 Nov 15;34(22):3089-3096. doi: 10.1089/neu.2017.5090. Epub 2017 Aug 4.

PMID:
28657491
28.

The Impact of Pediatric-Specific Vancomycin Dosing Guidelines: A Quality Improvement Initiative.

Miloslavsky M, Galler MF, Moawad I, Actis J, Cummings BM, El Saleeby CM.

Pediatrics. 2017 Jun;139(6). pii: e20162423. doi: 10.1542/peds.2016-2423. Epub 2017 May 11.

29.

Accept the Patient as a Person: With His or Her Complete Individualization.

Paris JJ, Cummings BM.

Am J Bioeth. 2017 Jun;17(6):43-44. doi: 10.1080/15265161.2017.1314705. No abstract available.

PMID:
28537839
30.

Brain uptake of deltamethrin in rats as a function of plasma protein binding and blood-brain barrier maturation.

Amaraneni M, Pang J, Mortuza TB, Muralidhara S, Cummings BS, White CA, Vorhees CV, Zastre J, Bruckner JV.

Neurotoxicology. 2017 Sep;62:24-29. doi: 10.1016/j.neuro.2017.04.009. Epub 2017 May 8.

PMID:
28495520
31.

Increasing Human Neural Stem Cell Transplantation Dose Alters Oligodendroglial and Neuronal Differentiation after Spinal Cord Injury.

Piltti KM, Funes GM, Avakian SN, Salibian AA, Huang KI, Carta K, Kamei N, Flanagan LA, Monuki ES, Uchida N, Cummings BJ, Anderson AJ.

Stem Cell Reports. 2017 Jun 6;8(6):1534-1548. doi: 10.1016/j.stemcr.2017.04.009. Epub 2017 May 4.

32.

Influence of Maturation on In Vivo Tissue to Plasma Partition Coefficients for Cis- and Trans-Permethrin.

Amaraneni M, Pang J, Bruckner JV, Muralidhara S, Mortuza TB, Gullick D, Hooshfar S, White CA, Cummings BS.

J Pharm Sci. 2017 Aug;106(8):2144-2151. doi: 10.1016/j.xphs.2017.04.024. Epub 2017 Apr 23.

PMID:
28445697
33.

iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases.

Abud EM, Ramirez RN, Martinez ES, Healy LM, Nguyen CHH, Newman SA, Yeromin AV, Scarfone VM, Marsh SE, Fimbres C, Caraway CA, Fote GM, Madany AM, Agrawal A, Kayed R, Gylys KH, Cahalan MD, Cummings BJ, Antel JP, Mortazavi A, Carson MJ, Poon WW, Blurton-Jones M.

Neuron. 2017 Apr 19;94(2):278-293.e9. doi: 10.1016/j.neuron.2017.03.042.

34.

Improving genetic diagnosis in Mendelian disease with transcriptome sequencing.

Cummings BB, Marshall JL, Tukiainen T, Lek M, Donkervoort S, Foley AR, Bolduc V, Waddell LB, Sandaradura SA, O'Grady GL, Estrella E, Reddy HM, Zhao F, Weisburd B, Karczewski KJ, O'Donnell-Luria AH, Birnbaum D, Sarkozy A, Hu Y, Gonorazky H, Claeys K, Joshi H, Bournazos A, Oates EC, Ghaoui R, Davis MR, Laing NG, Topf A; Genotype-Tissue Expression Consortium, Kang PB, Beggs AH, North KN, Straub V, Dowling JJ, Muntoni F, Clarke NF, Cooper ST, Bönnemann CG, MacArthur DG.

Sci Transl Med. 2017 Apr 19;9(386). pii: eaal5209. doi: 10.1126/scitranslmed.aal5209.

35.

Parent Participation in Pediatric Intensive Care Unit Rounds via Telemedicine: Feasibility and Impact.

Yager PH, Clark M, Cummings BM, Noviski N.

J Pediatr. 2017 Jun;185:181-186.e3. doi: 10.1016/j.jpeds.2017.02.054. Epub 2017 Mar 28.

PMID:
28363361
36.

The Practice of Radiation Oncology in Canada.

Lalani N, Cummings B, Halperin R, Rakovitch E, Brundage M, Vigneault E, Milosevic M.

Int J Radiat Oncol Biol Phys. 2017 Apr 1;97(5):876-880. doi: 10.1016/j.ijrobp.2016.11.055. Epub 2016 Dec 14. No abstract available.

PMID:
28333001
37.

Bridging Innovation and Outreach to Overcome Global Gaps in Radiation Oncology Through Information and Communication Tools, Trainee Advancement, Engaging Industry, Attention to Ethical Challenges, and Political Advocacy.

Dad L, Royce TJ, Morris Z, Moran M, Pawlicki T, Khuntia D, Hardenbergh P, Cummings B, Mayr N, Hu K.

Semin Radiat Oncol. 2017 Apr;27(2):98-108. doi: 10.1016/j.semradonc.2016.11.002. Epub 2016 Nov 9. Review.

PMID:
28325248
38.

Effect of Intensity Modulated Radiation Therapy With Concurrent Chemotherapy on Survival for Patients With Cervical Esophageal Carcinoma.

McDowell LJ, Huang SH, Xu W, Che J, Wong RKS, Brierley J, Kim J, Cummings B, Waldron J, Bayley A, Hansen A, Witterick I, Ringash J.

Int J Radiat Oncol Biol Phys. 2017 May 1;98(1):186-195. doi: 10.1016/j.ijrobp.2017.01.003. Epub 2017 Jan 9.

PMID:
28258892
39.

Pathogenic ASXL1 somatic variants in reference databases complicate germline variant interpretation for Bohring-Opitz Syndrome.

Carlston CM, O'Donnell-Luria AH, Underhill HR, Cummings BB, Weisburd B, Minikel EV, Birnbaum DP; Exome Aggregation Consortium, Tvrdik T, MacArthur DG, Mao R.

Hum Mutat. 2017 May;38(5):517-523. doi: 10.1002/humu.23203. Epub 2017 Mar 21. Review.

40.

Preclinical Efficacy Failure of Human CNS-Derived Stem Cells for Use in the Pathway Study of Cervical Spinal Cord Injury.

Anderson AJ, Piltti KM, Hooshmand MJ, Nishi RA, Cummings BJ.

Stem Cell Reports. 2017 Feb 14;8(2):249-263. doi: 10.1016/j.stemcr.2016.12.018.

41.

Response to StemCells Inc.

Monuki ES, Anderson AJ, Blurton-Jones M, Cummings BJ.

Stem Cell Reports. 2017 Feb 14;8(2):195-197. doi: 10.1016/j.stemcr.2017.02.002. No abstract available.

42.

Vertical sleeve gastrectomy reduces blood pressure and hypothalamic endoplasmic reticulum stress in mice.

McGavigan AK, Henseler ZM, Garibay D, Butler SD, Jayasinghe S, Ley RE, Davisson RL, Cummings BP.

Dis Model Mech. 2017 Mar 1;10(3):235-243. doi: 10.1242/dmm.027474. Epub 2017 Jan 12.

43.

Ensuring the quality of multiple-choice exams administered to small cohorts: A cautionary tale.

Young M, Cummings BA, St-Onge C.

Perspect Med Educ. 2017 Feb;6(1):21-28. doi: 10.1007/s40037-016-0322-0.

44.

Investigation of volumetric apparent diffusion coefficient histogram analysis for assessing complete response and clinical outcomes following pre-operative chemoradiation treatment for rectal carcinoma.

Chidambaram V, Brierley JD, Cummings B, Bhayana R, Menezes RJ, Kennedy ED, Kirsch R, Jhaveri KS.

Abdom Radiol (NY). 2017 May;42(5):1310-1318. doi: 10.1007/s00261-016-1010-6.

PMID:
28004138
45.

The ExAC browser: displaying reference data information from over 60 000 exomes.

Karczewski KJ, Weisburd B, Thomas B, Solomonson M, Ruderfer DM, Kavanagh D, Hamamsy T, Lek M, Samocha KE, Cummings BB, Birnbaum D; The Exome Aggregation Consortium, Daly MJ, MacArthur DG.

Nucleic Acids Res. 2017 Jan 4;45(D1):D840-D845. doi: 10.1093/nar/gkw971. Epub 2016 Nov 28.

46.

Diagnostic Uncertainty and Ethical Dilemmas in Medically Complex Pediatric Patients and Psychiatric Boarders.

Gardner K, Ruest S, Cummings B.

Hosp Pediatr. 2016 Nov;6(11):689-692. Epub 2016 Oct 7. No abstract available.

47.

Phase 1/2 Study of the Addition of Cisplatin to Adjuvant Chemotherapy With Image Guided High-Precision Radiation Therapy for Completely Resected Gastric Cancer.

Goody RB, MacKay H, Pitcher B, Oza A, Siu LL, Kim J, Wong RK, Chen E, Swallow C, Knox J, Kassam Z, Cummings B, Feld R, Hedley D, Liu G, Krzyzanowska MK, Dinniwell R, Brade AM, Dawson LA, Pintilie M, Ringash J.

Int J Radiat Oncol Biol Phys. 2016 Dec 1;96(5):994-1002. doi: 10.1016/j.ijrobp.2016.08.034. Epub 2016 Aug 31.

PMID:
27745984
48.

Variants in the Oxidoreductase PYROXD1 Cause Early-Onset Myopathy with Internalized Nuclei and Myofibrillar Disorganization.

O'Grady GL, Best HA, Sztal TE, Schartner V, Sanjuan-Vazquez M, Donkervoort S, Abath Neto O, Sutton RB, Ilkovski B, Romero NB, Stojkovic T, Dastgir J, Waddell LB, Boland A, Hu Y, Williams C, Ruparelia AA, Maisonobe T, Peduto AJ, Reddel SW, Lek M, Tukiainen T, Cummings BB, Joshi H, Nectoux J, Brammah S, Deleuze JF, Ing VO, Ramm G, Ardicli D, Nowak KJ, Talim B, Topaloglu H, Laing NG, North KN, MacArthur DG, Friant S, Clarke NF, Bryson-Richardson RJ, Bönnemann CG, Laporte J, Cooper ST.

Am J Hum Genet. 2016 Nov 3;99(5):1086-1105. doi: 10.1016/j.ajhg.2016.09.005. Epub 2016 Oct 13.

49.

Erratum: A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis.

Rivas MA, Graham D, Sulem P, Stevens C, Desch AN, Goyette P, Gudbjartsson D, Jonsdottir I, Thorsteinsdottir U, Degenhardt F, Mucha S, Kurki MI, Li D, D'Amato M, Annese V, Vermeire S, Weersma RK, Halfvarson J, Paavola-Sakki P, Lappalainen M, Lek M, Cummings B, Tukiainen T, Haritunians T, Halme L, Koskinen LL, Ananthakrishnan AN, Luo Y, Heap GA, Visschedijk MC; UK IBD Genetics Consortium; NIDDK IBD Genetics Consortium, MacArthur DG, Neale BM, Ahmad T, Anderson CA, Brant SR, Duerr RH, Silverberg MS, Cho JH, Palotie A, Saavalainen P, Kontula K, Färkkilä M, McGovern DP, Franke A, Stefansson K, Rioux JD, Xavier RJ, Daly MJ.

Nat Commun. 2016 Sep 13;7:12869. doi: 10.1038/ncomms12869. No abstract available.

50.

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