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Items: 1 to 50 of 134

1.

Biochemical Recurrence in Prostate Cancer: The European Association of Urology Prostate Cancer Guidelines Panel Recommendations.

Van den Broeck T, van den Bergh RCN, Briers E, Cornford P, Cumberbatch M, Tilki D, De Santis M, Fanti S, Fossati N, Gillessen S, Grummet JP, Henry AM, Lardas M, Liew M, Mason M, Moris L, Schoots IG, van der Kwast T, van der Poel H, Wiegel T, Willemse PM, Rouvière O, Lam TB, Mottet N.

Eur Urol Focus. 2019 Jun 24. pii: S2405-4569(19)30159-2. doi: 10.1016/j.euf.2019.06.004. [Epub ahead of print]

PMID:
31248850
2.

Impact of Anaesthetist Volume on Radical Cystectomy Outcomes.

Jubber I, Pang KH, Groves R, Reed O, Noon AP, Catto JWF, Cumberbatch MG.

Eur Urol Focus. 2019 May 6. pii: S2405-4569(19)30129-4. doi: 10.1016/j.euf.2019.04.013. [Epub ahead of print]

PMID:
31072807
3.

Factors associated with spontaneous stone passage in a contemporary cohort of patients presenting with acute ureteric colic: results from the Multi-centre cohort study evaluating the role of Inflammatory Markers In patients presenting with acute ureteric Colic (MIMIC) study.

Shah TT, Gao C, Peters M, Manning T, Cashman S, Nambiar A, Cumberbatch M, Lamb B, Peacock A, Van Son MJ, van Rossum PSN, Pickard R, Erotocritou P, Smith D, Kasivisvanathan V; British Urology Researchers in Surgical Training (BURST) Collaborative MIMIC Study Group.

BJU Int. 2019 Apr 18. doi: 10.1111/bju.14777. [Epub ahead of print]

PMID:
31001912
4.

Epidemiology, aetiology and screening of bladder cancer.

Cumberbatch MGK, Noon AP.

Transl Androl Urol. 2019 Feb;8(1):5-11. doi: 10.21037/tau.2018.09.11. Review.

5.

Testis-sparing surgery for testicular masses: current perspectives.

La Rocca R, Capece M, Spirito L, Cumberbatch MK, Creta M, Altieri V, Franco G, Albisinni S, Esperto F.

Minerva Urol Nefrol. 2019 Apr 5. doi: 10.23736/S0393-2249.19.03315-0. [Epub ahead of print]

PMID:
30957472
6.

Study Protocol for the DETECTIVE Study: An International Collaborative Study To Develop Consensus Statements for Deferred Treatment with Curative Intent for Localised Prostate Cancer.

Lam TBL, MacLennan S, Plass K, Willemse PM, Mason MD, Cornford P, Donaldson J, Davis NF, Dell'Oglio P, Fankhauser C, Grivas N, Ingels A, Lardas M, Liew M, Pang KH, Paterson C, Omar MI, Zattoni F, Buddingh KT, Van den Broeck T, Cumberbatch MG, Fossati N, Gross T, Moris L, Schoots IG, van den Bergh RCN, Briers E, Fanti S, De Santis M, Gillessen S, Grummet JP, Henry AM, van der Poel HG, van der Kwast TH, Rouvière O, Tilki D, Wiegel T, N'Dow J, Van Poppel H, Mottet N.

Eur Urol. 2019 Apr;75(4):699-702. doi: 10.1016/j.eururo.2018.11.009. Epub 2018 Nov 22. No abstract available.

PMID:
30473433
7.

Prognostic Value of Biochemical Recurrence Following Treatment with Curative Intent for Prostate Cancer: A Systematic Review.

Van den Broeck T, van den Bergh RCN, Arfi N, Gross T, Moris L, Briers E, Cumberbatch M, De Santis M, Tilki D, Fanti S, Fossati N, Gillessen S, Grummet JP, Henry AM, Lardas M, Liew M, Rouvière O, Pecanka J, Mason MD, Schoots IG, van Der Kwast TH, van Der Poel HG, Wiegel T, Willemse PM, Yuan Y, Lam TB, Cornford P, Mottet N.

Eur Urol. 2019 Jun;75(6):967-987. doi: 10.1016/j.eururo.2018.10.011. Epub 2018 Oct 17. Review.

PMID:
30342843
8.

Epidemiology of Bladder Cancer: A Systematic Review and Contemporary Update of Risk Factors in 2018.

Cumberbatch MGK, Jubber I, Black PC, Esperto F, Figueroa JD, Kamat AM, Kiemeney L, Lotan Y, Pang K, Silverman DT, Znaor A, Catto JWF.

Eur Urol. 2018 Dec;74(6):784-795. doi: 10.1016/j.eururo.2018.09.001. Epub 2018 Sep 26.

PMID:
30268659
9.

Combined Inhibition of PI3Kβ and mTOR Inhibits Growth of PTEN-null Tumors.

Lynch JT, Polanska UM, Hancox U, Delpuech O, Maynard J, Trigwell C, Eberlein C, Lenaghan C, Polanski R, Avivar-Valderas A, Cumberbatch M, Klinowska T, Critchlow SE, Cruzalegui F, Barry ST.

Mol Cancer Ther. 2018 Nov;17(11):2309-2319. doi: 10.1158/1535-7163.MCT-18-0183. Epub 2018 Aug 10.

PMID:
30097489
10.

Repeat Transurethral Resection in Non-muscle-invasive Bladder Cancer: A Systematic Review.

Cumberbatch MGK, Foerster B, Catto JWF, Kamat AM, Kassouf W, Jubber I, Shariat SF, Sylvester RJ, Gontero P.

Eur Urol. 2018 Jun;73(6):925-933. doi: 10.1016/j.eururo.2018.02.014. Epub 2018 Mar 6.

PMID:
29523366
11.

Re: Comprehensive Molecular Characterization of Muscle Invasive Bladder Cancer.

Cumberbatch MG, Catto JWF.

Eur Urol. 2017 Dec 5. pii: S0302-2838(17)31007-2. doi: 10.1016/j.eururo.2017.11.022. [Epub ahead of print] No abstract available.

12.

Inhibiting PI3Kβ with AZD8186 Regulates Key Metabolic Pathways in PTEN-Null Tumors.

Lynch JT, Polanska UM, Delpuech O, Hancox U, Trinidad AG, Michopoulos F, Lenaghan C, McEwen R, Bradford J, Polanski R, Ellston R, Avivar-Valderas A, Pilling J, Staniszewska A, Cumberbatch M, Critchlow SE, Cruzalegui F, Barry ST.

Clin Cancer Res. 2017 Dec 15;23(24):7584-7595. doi: 10.1158/1078-0432.CCR-17-0676. Epub 2017 Oct 2.

13.

The MEK inhibitor selumetinib complements CTLA-4 blockade by reprogramming the tumor immune microenvironment.

Poon E, Mullins S, Watkins A, Williams GS, Koopmann JO, Di Genova G, Cumberbatch M, Veldman-Jones M, Grosskurth SE, Sah V, Schuller A, Reimer C, Dovedi SJ, Smith PD, Stewart R, Wilkinson RW.

J Immunother Cancer. 2017 Aug 15;5(1):63. doi: 10.1186/s40425-017-0268-8.

14.

Quality of Life Outcomes after Primary Treatment for Clinically Localised Prostate Cancer: A Systematic Review.

Lardas M, Liew M, van den Bergh RC, De Santis M, Bellmunt J, Van den Broeck T, Cornford P, Cumberbatch MG, Fossati N, Gross T, Henry AM, Bolla M, Briers E, Joniau S, Lam TB, Mason MD, Mottet N, van der Poel HG, Rouvière O, Schoots IG, Wiegel T, Willemse PM, Yuan CY, Bourke L.

Eur Urol. 2017 Dec;72(6):869-885. doi: 10.1016/j.eururo.2017.06.035. Epub 2017 Jul 27. Review.

15.

The Use of Biomarkers to Manage Men with Metastatic Prostate Cancer: One Day, But Not Yet.

Cumberbatch MG, Catto JW.

Eur Urol Focus. 2016 Dec;2(5):467-468. doi: 10.1016/j.euf.2016.09.001. Epub 2016 Sep 15.

PMID:
28723507
16.

What Is the Negative Predictive Value of Multiparametric Magnetic Resonance Imaging in Excluding Prostate Cancer at Biopsy? A Systematic Review and Meta-analysis from the European Association of Urology Prostate Cancer Guidelines Panel.

Moldovan PC, Van den Broeck T, Sylvester R, Marconi L, Bellmunt J, van den Bergh RCN, Bolla M, Briers E, Cumberbatch MG, Fossati N, Gross T, Henry AM, Joniau S, van der Kwast TH, Matveev VB, van der Poel HG, De Santis M, Schoots IG, Wiegel T, Yuan CY, Cornford P, Mottet N, Lam TB, Rouvière O.

Eur Urol. 2017 Aug;72(2):250-266. doi: 10.1016/j.eururo.2017.02.026. Epub 2017 Mar 21. Review.

PMID:
28336078
17.

E-cigarettes and Urologic Health: A Collaborative Review of Toxicology, Epidemiology, and Potential Risks.

Bourke L, Bauld L, Bullen C, Cumberbatch M, Giovannucci E, Islami F, McRobbie H, Silverman DT, Catto JWF.

Eur Urol. 2017 Jun;71(6):915-923. doi: 10.1016/j.eururo.2016.12.022. Epub 2017 Jan 7. Review.

PMID:
28073600
18.

EAU-ESTRO-SIOG Guidelines on Prostate Cancer. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent.

Mottet N, Bellmunt J, Bolla M, Briers E, Cumberbatch MG, De Santis M, Fossati N, Gross T, Henry AM, Joniau S, Lam TB, Mason MD, Matveev VB, Moldovan PC, van den Bergh RCN, Van den Broeck T, van der Poel HG, van der Kwast TH, Rouvière O, Schoots IG, Wiegel T, Cornford P.

Eur Urol. 2017 Apr;71(4):618-629. doi: 10.1016/j.eururo.2016.08.003. Epub 2016 Aug 25.

PMID:
27568654
19.

The contemporary landscape of occupational bladder cancer within the United Kingdom: a meta-analysis of risks over the last 80 years.

Cumberbatch MG, Windsor-Shellard B, Catto JW.

BJU Int. 2017 Jan;119(1):100-109. doi: 10.1111/bju.13561. Epub 2016 Jul 26. Review.

20.

Micropapillary Variant Bladder Cancer: A Bad Apple or a New Fruit?

Cumberbatch MG, Catto JW.

Eur Urol. 2016 Oct;70(4):621-622. doi: 10.1016/j.eururo.2016.04.007. Epub 2016 Apr 29. No abstract available.

PMID:
27140723
21.

Intermittent High-Dose Scheduling of AZD8835, a Novel Selective Inhibitor of PI3Kα and PI3Kδ, Demonstrates Treatment Strategies for PIK3CA-Dependent Breast Cancers.

Hudson K, Hancox UJ, Trigwell C, McEwen R, Polanska UM, Nikolaou M, Morentin Gutierrez P, Avivar-Valderas A, Delpuech O, Dudley P, Hanson L, Ellston R, Jones A, Cumberbatch M, Cosulich SC, Ward L, Cruzalegui F, Green S.

Mol Cancer Ther. 2016 May;15(5):877-89. doi: 10.1158/1535-7163.MCT-15-0687. Epub 2016 Feb 2.

22.

Contemporary Occupational Carcinogen Exposure and Bladder Cancer: A Systematic Review and Meta-analysis.

Cumberbatch MG, Cox A, Teare D, Catto JW.

JAMA Oncol. 2015 Dec;1(9):1282-90. doi: 10.1001/jamaoncol.2015.3209. Review. Erratum in: JAMA Oncol. 2015 Dec;1(9):1224.

PMID:
26448641
24.

The Role of Tobacco Smoke in Bladder and Kidney Carcinogenesis: A Comparison of Exposures and Meta-analysis of Incidence and Mortality Risks.

Cumberbatch MG, Rota M, Catto JW, La Vecchia C.

Eur Urol. 2016 Sep;70(3):458-66. doi: 10.1016/j.eururo.2015.06.042. Epub 2015 Jul 3. Review.

25.

Luzp4 defines a new mRNA export pathway in cancer cells.

Viphakone N, Cumberbatch MG, Livingstone MJ, Heath PR, Dickman MJ, Catto JW, Wilson SA.

Nucleic Acids Res. 2015 Feb 27;43(4):2353-66. doi: 10.1093/nar/gkv070. Epub 2015 Feb 6.

26.

Inhibition of PI3Kβ signaling with AZD8186 inhibits growth of PTEN-deficient breast and prostate tumors alone and in combination with docetaxel.

Hancox U, Cosulich S, Hanson L, Trigwell C, Lenaghan C, Ellston R, Dry H, Crafter C, Barlaam B, Fitzek M, Smith PD, Ogilvie D, D'Cruz C, Castriotta L, Wedge SR, Ward L, Powell S, Lawson M, Davies BR, Harrington EA, Foster E, Cumberbatch M, Green S, Barry ST.

Mol Cancer Ther. 2015 Jan;14(1):48-58. doi: 10.1158/1535-7163.MCT-14-0406. Epub 2014 Nov 14.

27.

Identification of a subset of human non-small cell lung cancer patients with high PI3Kβ and low PTEN expression, more prevalent in squamous cell carcinoma.

Cumberbatch M, Tang X, Beran G, Eckersley S, Wang X, Ellston RP, Dearden S, Cosulich S, Smith PD, Behrens C, Kim ES, Su X, Fan S, Gray N, Blowers DP, Wistuba II, Womack C.

Clin Cancer Res. 2014 Feb 1;20(3):595-603. doi: 10.1158/1078-0432.CCR-13-1638. Epub 2013 Nov 27.

28.

Digital pattern recognition-based image analysis quantifies immune infiltrates in distinct tissue regions of colorectal cancer and identifies a metastatic phenotype.

Angell HK, Gray N, Womack C, Pritchard DI, Wilkinson RW, Cumberbatch M.

Br J Cancer. 2013 Sep 17;109(6):1618-24. doi: 10.1038/bjc.2013.487. Epub 2013 Aug 20.

29.

AZD3514: a small molecule that modulates androgen receptor signaling and function in vitro and in vivo.

Loddick SA, Ross SJ, Thomason AG, Robinson DM, Walker GE, Dunkley TP, Brave SR, Broadbent N, Stratton NC, Trueman D, Mouchet E, Shaheen FS, Jacobs VN, Cumberbatch M, Wilson J, Jones RD, Bradbury RH, Rabow A, Gaughan L, Womack C, Barry ST, Robson CN, Critchlow SE, Wedge SR, Brooks AN.

Mol Cancer Ther. 2013 Sep;12(9):1715-27. doi: 10.1158/1535-7163.MCT-12-1174. Epub 2013 Jul 16.

30.

No impairment of monocyte-derived Langerhans cell phenotype or function in early-onset psoriasis.

Shaw FL, Kimber I, Begum R, Cumberbatch M, Dearman RJ, Griffiths CE.

Clin Exp Dermatol. 2012 Jan;37(1):40-7. doi: 10.1111/j.1365-2230.2011.04172.x. Epub 2011 Sep 20.

31.

Langerhans cell mobilization distinguishes between early-onset and late-onset psoriasis.

Shaw FL, Cumberbatch M, Kleyn CE, Begum R, Dearman RJ, Kimber I, Griffiths CE.

J Invest Dermatol. 2010 Jul;130(7):1940-2. doi: 10.1038/jid.2010.57. Epub 2010 Mar 18. No abstract available.

32.

The cutaneous biochemical redox barrier: a component of the innate immune defenses against sensitization by highly reactive environmental xenobiotics.

Pickard C, Louafi F, McGuire C, Lowings K, Kumar P, Cooper H, Dearman RJ, Cumberbatch M, Kimber I, Healy E, Friedmann PS.

J Immunol. 2009 Dec 1;183(11):7576-84. doi: 10.4049/jimmunol.0901064. Epub 2009 Nov 4.

33.

Langerhans cell migration: not necessarily always at the center of the skin sensitization universe.

Kimber I, Cumberbatch M, Dearman RJ.

J Invest Dermatol. 2009 Aug;129(8):1852-3. doi: 10.1038/jid.2009.54.

34.

Synergistic effects of chemical insult and toll-like receptor ligands on dendritic cell activation.

Dearman RJ, Cumberbatch M, Portsmouth C, Maxwell G, Basketter DA, Kimber I.

Toxicol In Vitro. 2008 Dec;22(8):1927-34. doi: 10.1016/j.tiv.2008.09.012. Epub 2008 Sep 23.

PMID:
18848616
35.

Toll-like receptor ligand activation of murine bone marrow-derived dendritic cells.

Dearman RJ, Cumberbatch M, Maxwell G, Basketter DA, Kimber I.

Immunology. 2009 Apr;126(4):475-84. doi: 10.1111/j.1365-2567.2008.02922.x. Epub 2008 Sep 4.

36.

The effects of acute social stress on epidermal Langerhans' cell frequency and expression of cutaneous neuropeptides.

Kleyn CE, Schneider L, Saraceno R, Mantovani C, Richards HL, Fortune DG, Cumberbatch M, Dearman RJ, Terenghi G, Kimber I, Griffiths CE.

J Invest Dermatol. 2008 May;128(5):1273-9. Epub 2007 Nov 8.

37.

IL-18 is a key proximal mediator of contact hypersensitivity and allergen-induced Langerhans cell migration in murine epidermis.

Antonopoulos C, Cumberbatch M, Mee JB, Dearman RJ, Wei XQ, Liew FY, Kimber I, Groves RW.

J Leukoc Biol. 2008 Feb;83(2):361-7. Epub 2007 Nov 5.

PMID:
17984289
38.

Proteomic analysis of suction blister fluid isolated from human skin.

Macdonald N, Cumberbatch M, Singh M, Moggs JG, Orphanides G, Dearman RJ, Griffiths CE, Kimber I.

Clin Exp Dermatol. 2006 May;31(3):445-8.

PMID:
16681597
39.

Impaired Langerhans cell migration in psoriasis.

Cumberbatch M, Singh M, Dearman RJ, Young HS, Kimber I, Griffiths CE.

J Exp Med. 2006 Apr 17;203(4):953-60. Epub 2006 Mar 27.

40.

Cytokines and Langerhans cell mobilisation in mouse and man.

Griffiths CE, Dearman RJ, Cumberbatch M, Kimber I.

Cytokine. 2005 Oct 21;32(2):67-70. Epub 2005 Sep 8. Review.

PMID:
16153855
41.

Interactions of contact allergens with dendritic cells: opportunities and challenges for the development of novel approaches to hazard assessment.

Ryan CA, Gerberick GF, Gildea LA, Hulette BC, Betts CJ, Cumberbatch M, Dearman RJ, Kimber I.

Toxicol Sci. 2005 Nov;88(1):4-11. Epub 2005 Jul 13. Review.

PMID:
16014741
42.

Impact of cutaneous IL-10 on resident epidermal Langerhans' cells and the development of polarized immune responses.

Cumberbatch M, Clelland K, Dearman RJ, Kimber I.

J Immunol. 2005 Jul 1;175(1):43-50.

43.

Measurement of cytokine expression and Langerhans cell migration in human skin following suction blister formation.

Dearman RJ, Bhushan M, Cumberbatch M, Kimber I, Griffiths CE.

Exp Dermatol. 2004 Jul;13(7):452-60.

PMID:
15217366
44.

Exogenous interleukin-1beta restores impaired Langerhans cell migration in aged skin.

Bhushan M, Cumberbatch M, Dearman RJ, Kimber I, Griffiths CE.

Br J Dermatol. 2004 Jun;150(6):1217-8. No abstract available.

PMID:
15214919
45.

Dendritic cells and skin sensitisation hazard assessment.

Kimber I, Cumberbatch M, Betts CJ, Dearman RJ.

Toxicol In Vitro. 2004 Apr;18(2):195-202. Review.

PMID:
14757110
46.

Epidermal Langerhans cell migration and sensitisation to chemical allergens.

Cumberbatch M, Dearman RJ, Griffiths CE, Kimber I.

APMIS. 2003 Jul-Aug;111(7-8):797-804. Review.

PMID:
12974781
47.

IL-1beta-induced Langerhans' cell migration and TNF-alpha production in human skin: regulation by lactoferrin.

Cumberbatch M, Bhushan M, Dearman RJ, Kimber I, Griffiths CE.

Clin Exp Immunol. 2003 May;132(2):352-9.

48.

Assessment of glycosylation-dependent cell adhesion molecule 1 as a correlate of allergen-stimulated lymph node activation.

Betts CJ, Moggs JG, Caddick HT, Cumberbatch M, Orphanides G, Dearman RJ, Ryan CA, Hulette BC, Frank Gerberick G, Kimber I.

Toxicology. 2003 Mar 14;185(1-2):103-17.

PMID:
12505449
49.

Danger signals and skin sensitization.

Kimber I, Cumberbatch M, Dearman RJ, Griffiths CE.

Br J Dermatol. 2002 Sep;147(3):613-4. No abstract available.

PMID:
12207617
50.

Substance P (neurokinin 1) receptor antagonists enhance dorsal raphe neuronal activity.

Conley RK, Cumberbatch MJ, Mason GS, Williamson DJ, Harrison T, Locker K, Swain C, Maubach K, O'Donnell R, Rigby M, Hewson L, Smith D, Rupniak NM.

J Neurosci. 2002 Sep 1;22(17):7730-6.

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