Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 316

1.

Targeting HPV16 DNA using CRISPR/Cas inhibits anal cancer growth in vivo.

Hsu DS, Kornepati AV, Glover W, Kennedy EM, Cullen BR.

Future Virol. 2018 Jul;13(7):475-482. doi: 10.2217/fvl-2018-0010. Epub 2018 Jun 12.

2.

Influenza A virus-derived siRNAs increase in the absence of NS1 yet fail to inhibit virus replication.

Tsai K, Courtney DG, Kennedy EM, Cullen BR.

RNA. 2018 Sep;24(9):1172-1182. doi: 10.1261/rna.066332.118. Epub 2018 Jun 14.

PMID:
29903832
3.

Insights into the mechanisms underlying the inactivation of HIV-1 proviruses by CRISPR/Cas.

Mefferd AL, Bogerd HP, Irwan ID, Cullen BR.

Virology. 2018 Jul;520:116-126. doi: 10.1016/j.virol.2018.05.016. Epub 2018 May 29.

PMID:
29857168
4.

Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication.

Tsai K, Courtney DG, Cullen BR.

PLoS Pathog. 2018 Feb 15;14(2):e1006919. doi: 10.1371/journal.ppat.1006919. eCollection 2018 Feb.

5.

Posttranscriptional m6A Editing of HIV-1 mRNAs Enhances Viral Gene Expression.

Kennedy EM, Bogerd HP, Kornepati AVR, Kang D, Ghoshal D, Marshall JB, Poling BC, Tsai K, Gokhale NS, Horner SM, Cullen BR.

Cell Host Microbe. 2017 Dec 13;22(6):830. doi: 10.1016/j.chom.2017.11.010. No abstract available.

6.

Viruses hijack a long non-coding RNA.

Heaton NS, Cullen BR.

Nature. 2017 Dec 14;552(7684):184-185. doi: 10.1038/d41586-017-07692-w. No abstract available.

PMID:
29239386
7.

The Epstein-Barr virus miR-BHRF1 microRNAs regulate viral gene expression in cis.

Poling BC, Price AM, Luftig MA, Cullen BR.

Virology. 2017 Dec;512:113-123. doi: 10.1016/j.virol.2017.09.015.

PMID:
28950226
8.

Epitranscriptomic Enhancement of Influenza A Virus Gene Expression and Replication.

Courtney DG, Kennedy EM, Dumm RE, Bogerd HP, Tsai K, Heaton NS, Cullen BR.

Cell Host Microbe. 2017 Sep 13;22(3):377-386.e5. doi: 10.1016/j.chom.2017.08.004.

9.

RNA Interference in Mammals: The Virus Strikes Back.

Cullen BR.

Immunity. 2017 Jun 20;46(6):970-972. doi: 10.1016/j.immuni.2017.05.004.

10.

A lentiviral vector bearing a reverse intron demonstrates superior expression of both proteins and microRNAs.

Poling BC, Tsai K, Kang D, Ren L, Kennedy EM, Cullen BR.

RNA Biol. 2017 Nov 2;14(11):1570-1579. doi: 10.1080/15476286.2017.1334755. Epub 2017 Jul 21.

11.

Viral Epitranscriptomics.

Kennedy EM, Courtney DG, Tsai K, Cullen BR.

J Virol. 2017 Apr 13;91(9). pii: e02263-16. doi: 10.1128/JVI.02263-16. Print 2017 May 1. Review.

12.

Induced Packaging of Cellular MicroRNAs into HIV-1 Virions Can Inhibit Infectivity.

Bogerd HP, Kennedy EM, Whisnant AW, Cullen BR.

MBio. 2017 Jan 17;8(1). pii: e02125-16. doi: 10.1128/mBio.02125-16.

13.

Partial reconstitution of the RNAi response in human cells using Drosophila gene products.

Kennedy EM, Kornepati AV, Bogerd HP, Cullen BR.

RNA. 2017 Feb;23(2):153-160. doi: 10.1261/rna.059345.116. Epub 2016 Nov 11.

14.

Gene Editing: A New Tool for Viral Disease.

Kennedy EM, Cullen BR.

Annu Rev Med. 2017 Jan 14;68:401-411. doi: 10.1146/annurev-med-051215-031129. Epub 2016 Aug 26. Review.

PMID:
27576009
15.

Posttranscriptional m(6)A Editing of HIV-1 mRNAs Enhances Viral Gene Expression.

Kennedy EM, Bogerd HP, Kornepati AV, Kang D, Ghoshal D, Marshall JB, Poling BC, Tsai K, Gokhale NS, Horner SM, Cullen BR.

Cell Host Microbe. 2016 May 11;19(5):675-85. doi: 10.1016/j.chom.2016.04.002. Epub 2016 Apr 21. Erratum in: Cell Host Microbe. 2017 Dec 13;22(6):830.

16.

A model of milk production in lactating dairy cows in relation to energy and nitrogen dynamics.

Johnson IR, France J, Cullen BR.

J Dairy Sci. 2016 Feb;99(2):1605-1618. doi: 10.3168/jds.2015-10068. Epub 2015 Dec 10.

PMID:
26686718
17.

Specific induction of endogenous viral restriction factors using CRISPR/Cas-derived transcriptional activators.

Bogerd HP, Kornepati AV, Marshall JB, Kennedy EM, Cullen BR.

Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):E7249-56. doi: 10.1073/pnas.1516305112. Epub 2015 Dec 14.

18.

Production of functional small interfering RNAs by an amino-terminal deletion mutant of human Dicer.

Kennedy EM, Whisnant AW, Kornepati AV, Marshall JB, Bogerd HP, Cullen BR.

Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):E6945-54. doi: 10.1073/pnas.1513421112. Epub 2015 Nov 30. Erratum in: Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):E6547.

19.

Characterization of Staphylococcus aureus Cas9: a smaller Cas9 for all-in-one adeno-associated virus delivery and paired nickase applications.

Friedland AE, Baral R, Singhal P, Loveluck K, Shen S, Sanchez M, Marco E, Gotta GM, Maeder ML, Kennedy EM, Kornepati AV, Sousa A, Collins MA, Jayaram H, Cullen BR, Bumcrot D.

Genome Biol. 2015 Nov 24;16:257. doi: 10.1186/s13059-015-0817-8.

20.

Targeting hepatitis B virus cccDNA using CRISPR/Cas9.

Kennedy EM, Kornepati AV, Cullen BR.

Antiviral Res. 2015 Nov;123:188-92. doi: 10.1016/j.antiviral.2015.10.004. Epub 2015 Oct 22. Review.

PMID:
26476375
21.

EBV Noncoding RNAs.

Skalsky RL, Cullen BR.

Curr Top Microbiol Immunol. 2015;391:181-217. doi: 10.1007/978-3-319-22834-1_6. Review.

22.

Epstein-Barr Viruses (EBVs) Deficient in EBV-Encoded RNAs Have Higher Levels of Latent Membrane Protein 2 RNA Expression in Lymphoblastoid Cell Lines and Efficiently Establish Persistent Infections in Humanized Mice.

Gregorovic G, Boulden EA, Bosshard R, Elgueta Karstegl C, Skalsky R, Cullen BR, Gujer C, Rämer P, Münz C, Farrell PJ.

J Virol. 2015 Nov;89(22):11711-4. doi: 10.1128/JVI.01873-15. Epub 2015 Sep 2.

23.

Optimization of a multiplex CRISPR/Cas system for use as an antiviral therapeutic.

Kennedy EM, Kornepati AVR, Mefferd AL, Marshall JB, Tsai K, Bogerd HP, Cullen BR.

Methods. 2015 Dec;91:82-86. doi: 10.1016/j.ymeth.2015.08.012. Epub 2015 Aug 17.

24.

Expression of CRISPR/Cas single guide RNAs using small tRNA promoters.

Mefferd AL, Kornepati AV, Bogerd HP, Kennedy EM, Cullen BR.

RNA. 2015 Sep;21(9):1683-9. doi: 10.1261/rna.051631.115. Epub 2015 Jul 17.

25.

EBV BART MicroRNAs Target Multiple Pro-apoptotic Cellular Genes to Promote Epithelial Cell Survival.

Kang D, Skalsky RL, Cullen BR.

PLoS Pathog. 2015 Jun 12;11(6):e1004979. doi: 10.1371/journal.ppat.1004979. eCollection 2015 Jun.

26.

The virology-RNA biology connection.

Cullen BR.

RNA. 2015 Apr;21(4):592-4. doi: 10.1261/rna.049882.115. No abstract available.

27.

Bacterial CRISPR/Cas DNA endonucleases: A revolutionary technology that could dramatically impact viral research and treatment.

Kennedy EM, Cullen BR.

Virology. 2015 May;479-480:213-20. doi: 10.1016/j.virol.2015.02.024. Epub 2015 Mar 7. Review.

28.

Suppression of hepatitis B virus DNA accumulation in chronically infected cells using a bacterial CRISPR/Cas RNA-guided DNA endonuclease.

Kennedy EM, Bassit LC, Mueller H, Kornepati AVR, Bogerd HP, Nie T, Chatterjee P, Javanbakht H, Schinazi RF, Cullen BR.

Virology. 2015 Feb;476:196-205. doi: 10.1016/j.virol.2014.12.001. Epub 2014 Dec 29.

29.

HIV-1 Packing to Leave.

Cullen BR.

Cell. 2014 Nov 20;159(5):975-976. doi: 10.1016/j.cell.2014.11.008.

30.

Viruses and RNA interference: issues and controversies.

Cullen BR.

J Virol. 2014 Nov;88(22):12934-6. doi: 10.1128/JVI.01179-14. Epub 2014 Sep 10. Review.

31.

Search for microRNAs expressed by intracellular bacterial pathogens in infected mammalian cells.

Furuse Y, Finethy R, Saka HA, Xet-Mull AM, Sisk DM, Smith KL, Lee S, Coers J, Valdivia RH, Tobin DM, Cullen BR.

PLoS One. 2014 Sep 3;9(9):e106434. doi: 10.1371/journal.pone.0106434. eCollection 2014.

32.

Inactivation of the human papillomavirus E6 or E7 gene in cervical carcinoma cells by using a bacterial CRISPR/Cas RNA-guided endonuclease.

Kennedy EM, Kornepati AV, Goldstein M, Bogerd HP, Poling BC, Whisnant AW, Kastan MB, Cullen BR.

J Virol. 2014 Oct;88(20):11965-72. doi: 10.1128/JVI.01879-14. Epub 2014 Aug 6.

33.

A "microRNA-like" small RNA expressed by Dengue virus?

Skalsky RL, Olson KE, Blair CD, Garcia-Blanco MA, Cullen BR.

Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):E2359. doi: 10.1073/pnas.1406854111. Epub 2014 May 22. No abstract available.

34.

Replication of many human viruses is refractory to inhibition by endogenous cellular microRNAs.

Bogerd HP, Skalsky RL, Kennedy EM, Furuse Y, Whisnant AW, Flores O, Schultz KL, Putnam N, Barrows NJ, Sherry B, Scholle F, Garcia-Blanco MA, Griffin DE, Cullen BR.

J Virol. 2014 Jul;88(14):8065-76. doi: 10.1128/JVI.00985-14. Epub 2014 May 7.

35.

Derivation and characterization of Dicer- and microRNA-deficient human cells.

Bogerd HP, Whisnant AW, Kennedy EM, Flores O, Cullen BR.

RNA. 2014 Jun;20(6):923-37. doi: 10.1261/rna.044545.114. Epub 2014 Apr 22.

36.

Analysis of viral microRNA expression by elephant endotheliotropic herpesvirus 1.

Furuse Y, Dastjerdi A, Seilern-Moy K, Steinbach F, Cullen BR.

Virology. 2014 Apr;454-455:102-8. doi: 10.1016/j.virol.2014.02.009. Epub 2014 Feb 28.

37.

A neuron-specific host microRNA targets herpes simplex virus-1 ICP0 expression and promotes latency.

Pan D, Flores O, Umbach JL, Pesola JM, Bentley P, Rosato PC, Leib DA, Cullen BR, Coen DM.

Cell Host Microbe. 2014 Apr 9;15(4):446-56. doi: 10.1016/j.chom.2014.03.004.

38.

Identification of novel, highly expressed retroviral microRNAs in cells infected by bovine foamy virus.

Whisnant AW, Kehl T, Bao Q, Materniak M, Kuzmak J, Löchelt M, Cullen BR.

J Virol. 2014 May;88(9):4679-86. doi: 10.1128/JVI.03587-13. Epub 2014 Feb 12.

39.

Differential RISC association of endogenous human microRNAs predicts their inhibitory potential.

Flores O, Kennedy EM, Skalsky RL, Cullen BR.

Nucleic Acids Res. 2014 Apr;42(7):4629-39. doi: 10.1093/nar/gkt1393. Epub 2014 Jan 23.

40.

Analysis of the mRNA targetome of microRNAs expressed by Marek's disease virus.

Parnas O, Corcoran DL, Cullen BR.

MBio. 2014 Jan 21;5(1):e01060-13. doi: 10.1128/mBio.01060-13.

41.

Evolutionary conservation of primate lymphocryptovirus microRNA targets.

Skalsky RL, Kang D, Linnstaedt SD, Cullen BR.

J Virol. 2014 Feb;88(3):1617-35. doi: 10.1128/JVI.02071-13. Epub 2013 Nov 20.

42.

How do viruses avoid inhibition by endogenous cellular microRNAs?

Cullen BR.

PLoS Pathog. 2013;9(11):e1003694. doi: 10.1371/journal.ppat.1003694. Epub 2013 Nov 7. Review. No abstract available.

43.

Persistently adenovirus-infected lymphoid cells express microRNAs derived from the viral VAI and especially VAII RNA.

Furuse Y, Ornelles DA, Cullen BR.

Virology. 2013 Dec;447(1-2):140-5. doi: 10.1016/j.virol.2013.08.024. Epub 2013 Sep 26.

44.

Is RNA interference a physiologically relevant innate antiviral immune response in mammals?

Cullen BR, Cherry S, tenOever BR.

Cell Host Microbe. 2013 Oct 16;14(4):374-8. doi: 10.1016/j.chom.2013.09.011. Review.

45.

MicroRNA-17~92 plays a causative role in lymphomagenesis by coordinating multiple oncogenic pathways.

Jin HY, Oda H, Lai M, Skalsky RL, Bethel K, Shepherd J, Kang SG, Liu WH, Sabouri-Ghomi M, Cullen BR, Rajewsky K, Xiao C.

EMBO J. 2013 Aug 28;32(17):2377-91. doi: 10.1038/emboj.2013.178. Epub 2013 Aug 6.

46.

MicroRNA target site identification by integrating sequence and binding information.

Majoros WH, Lekprasert P, Mukherjee N, Skalsky RL, Corcoran DL, Cullen BR, Ohler U.

Nat Methods. 2013 Jul;10(7):630-3. doi: 10.1038/nmeth.2489. Epub 2013 May 26.

47.

In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms.

Whisnant AW, Bogerd HP, Flores O, Ho P, Powers JG, Sharova N, Stevenson M, Chen CH, Cullen BR.

MBio. 2013 Apr 16;4(2):e000193. doi: 10.1128/mBio.00193-13.

48.

Mutational inactivation of herpes simplex virus 1 microRNAs identifies viral mRNA targets and reveals phenotypic effects in culture.

Flores O, Nakayama S, Whisnant AW, Javanbakht H, Cullen BR, Bloom DC.

J Virol. 2013 Jun;87(12):6589-603. doi: 10.1128/JVI.00504-13. Epub 2013 Mar 27.

49.

Making a NeST for a persistent virus.

Cullen BR.

Cell Host Microbe. 2013 Mar 13;13(3):241-2. doi: 10.1016/j.chom.2013.02.016.

50.

A cluster of virus-encoded microRNAs accelerates acute systemic Epstein-Barr virus infection but does not significantly enhance virus-induced oncogenesis in vivo.

Wahl A, Linnstaedt SD, Esoda C, Krisko JF, Martinez-Torres F, Delecluse HJ, Cullen BR, Garcia JV.

J Virol. 2013 May;87(10):5437-46. doi: 10.1128/JVI.00281-13. Epub 2013 Mar 6.

Supplemental Content

Loading ...
Support Center